JP2009068977A - 測定装置 - Google Patents
測定装置 Download PDFInfo
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- JP2009068977A JP2009068977A JP2007237320A JP2007237320A JP2009068977A JP 2009068977 A JP2009068977 A JP 2009068977A JP 2007237320 A JP2007237320 A JP 2007237320A JP 2007237320 A JP2007237320 A JP 2007237320A JP 2009068977 A JP2009068977 A JP 2009068977A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0097—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying acoustic waves and detecting light, i.e. acoustooptic measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
- G01N2021/1727—Magnetomodulation
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- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Acoustics & Sound (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Abstract
【解決手段】被検体Eの分光特性を音響光学トモグラフィを利用して測定する測定装置であって、被検体Eに照射する光を発生する光源部100と、超音波を発生する超音波発生部5aと、超音波発生部5aからの超音波を被検体Eの被検部位Xに集束する超音波集束部5bと、被検体Eの被検部位Xにおいて音響光学効果により光が変調された変調光を検出する光検出部400と、光検出部400の出力に基づいて、超音波発生部5aが発生する超音波の強度、その超音波の周波数、超音波集束部5bが集束する超音波の集束サイズ、光源部100からの光の強度の少なくとも一つを制御する制御部600と、を有する測定装置を提供する。
【選択図】図1
Description
5b 超音波集束部
100 光源部
400 光検出部
500 信号解析部
600 制御部
800 超音波検出部
900 モード切替スイッチ
950 入力部
Claims (9)
- 被検体の分光特性を音響光学トモグラフィを利用して測定する測定装置において、
前記被検体に照射する光を発生する光源部と、
超音波を発生する超音波発生部と、
前記超音波発生部からの超音波を前記被検体の被検部位に集束する超音波集束部と、
前記被検体の前記被検部位において音響光学効果により前記光が変調された変調光を検出する光検出部と、
前記光検出部の出力に基づいて、前記超音波発生部が発生する前記超音波の強度、超音波の周波数、前記超音波集束部が集束する前記超音波の集束サイズ、前記光源部からの前記光の強度の少なくとも一つを制御する制御部と、を有することを特徴とする測定装置。 - 前記変調光の信号レベルを光検出部のノイズレベルと比較し、前記制御部に比較結果を通知する信号解析部を更に有することを特徴とする請求項1に記載の測定装置。
- 前記信号解析部は、集束位置の座標データと当該座標データに対応した前記変調光の光信号から被検体内の分光特性の分布データを作成することを特徴とする請求項2に記載の測定装置。
- 前記制御部は、前記超音波集束部による前記超音波の集束位置を走査し、前記超音波の第1の集束位置において前記変調光のSN比が閾値以下である場合に前記超音波の強度及び周波数、前記超音波の集束サイズ、及び、前記光の強度の少なくとも一つを初期値から増加することによって前記第1の走査位置の測定をやり直し、前記第1の集束位置とは異なる第2の集束位置においては前記第1の集束位置のために変更された前記少なくとも一つを初期値に戻して測定を行うことを特徴とする請求項1に記載の測定装置。
- 被検体の分光特性を音響光学トモグラフィを利用して測定する測定装置において、
超音波を発生する超音波発生部と、
前記超音波発生部からの超音波を前記被検体の被検部位に集束する超音波集束部と、
ラフスキャンモードとファインスキャンモードとの間でモードを切り替えるモード切替スイッチと、
前記モード切替スイッチが前記ファインスキャンモードを設定している場合にはラフスキャンモードよりも前記超音波の集束サイズを小さく設定する前記制御部と、を有することを特徴とする測定装置。 - 前記被検体における被検部位の測定領域を設定する測定領域設定部を更に有することを特徴とする請求項5に記載の測定装置。
- 前記超音波集束部による前記集束サイズを設定する集束サイズ設定装置を更に有することを特徴とする請求項5に記載の測定装置。
- 前記測定装置は、前記超音波を検出する超音波検出部を更に有し、
前記制御部は、前記超音波検出部の検出結果に基づいて前記超音波発生部が発生する超音波の強度を制御することを特徴とする請求項1乃至7のうちいずれか一項に記載の測定装置。 - 前記超音波発生部と前記超音波検出部は一つの超音波トランスデューサで構成されることを特徴とする請求項8に記載の測定装置。
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007237320A JP5317449B2 (ja) | 2007-09-12 | 2007-09-12 | 測定装置 |
EP08164180.5A EP2036490B1 (en) | 2007-09-12 | 2008-09-11 | Measurement apparatus |
US12/209,556 US20090069676A1 (en) | 2007-09-12 | 2008-09-12 | Measurement apparatus |
Applications Claiming Priority (1)
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JP2007237320A JP5317449B2 (ja) | 2007-09-12 | 2007-09-12 | 測定装置 |
Publications (3)
Publication Number | Publication Date |
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JP2009068977A true JP2009068977A (ja) | 2009-04-02 |
JP2009068977A5 JP2009068977A5 (ja) | 2010-10-28 |
JP5317449B2 JP5317449B2 (ja) | 2013-10-16 |
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JP2007237320A Expired - Fee Related JP5317449B2 (ja) | 2007-09-12 | 2007-09-12 | 測定装置 |
Country Status (3)
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US (1) | US20090069676A1 (ja) |
EP (1) | EP2036490B1 (ja) |
JP (1) | JP5317449B2 (ja) |
Cited By (15)
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JP2010071692A (ja) * | 2008-09-16 | 2010-04-02 | Canon Inc | 測定装置及び測定方法 |
WO2011091360A2 (en) * | 2010-01-25 | 2011-07-28 | Washington University | Optical time reversal by ultrasonic encoding in biological tissue |
US8997572B2 (en) | 2011-02-11 | 2015-04-07 | Washington University | Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection |
US9086365B2 (en) | 2010-04-09 | 2015-07-21 | Lihong Wang | Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography |
US9226666B2 (en) | 2007-10-25 | 2016-01-05 | Washington University | Confocal photoacoustic microscopy with optical lateral resolution |
US9335605B2 (en) | 2010-01-25 | 2016-05-10 | Washington University | Iteration of optical time reversal by ultrasonic encoding in biological tissue |
US9351705B2 (en) | 2009-01-09 | 2016-05-31 | Washington University | Miniaturized photoacoustic imaging apparatus including a rotatable reflector |
JP2017040662A (ja) * | 2016-10-31 | 2017-02-23 | 株式会社アクロエッジ | 測定方法 |
US11020006B2 (en) | 2012-10-18 | 2021-06-01 | California Institute Of Technology | Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data |
US11137375B2 (en) | 2013-11-19 | 2021-10-05 | California Institute Of Technology | Systems and methods of grueneisen-relaxation photoacoustic microscopy and photoacoustic wavefront shaping |
US11369280B2 (en) | 2019-03-01 | 2022-06-28 | California Institute Of Technology | Velocity-matched ultrasonic tagging in photoacoustic flowgraphy |
US11530979B2 (en) | 2018-08-14 | 2022-12-20 | California Institute Of Technology | Multifocal photoacoustic microscopy through an ergodic relay |
US11592652B2 (en) | 2018-09-04 | 2023-02-28 | California Institute Of Technology | Enhanced-resolution infrared photoacoustic microscopy and spectroscopy |
US11672426B2 (en) | 2017-05-10 | 2023-06-13 | California Institute Of Technology | Snapshot photoacoustic photography using an ergodic relay |
US11986269B2 (en) | 2019-11-05 | 2024-05-21 | California Institute Of Technology | Spatiotemporal antialiasing in photoacoustic computed tomography |
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JP2009066110A (ja) * | 2007-09-12 | 2009-04-02 | Canon Inc | 測定装置 |
JP5219440B2 (ja) * | 2007-09-12 | 2013-06-26 | キヤノン株式会社 | 測定装置 |
EP2260754A1 (en) * | 2009-06-10 | 2010-12-15 | Universiteit Twente | Device and method for photon absorption coefficient measurement |
JP5641773B2 (ja) * | 2010-04-28 | 2014-12-17 | キヤノン株式会社 | 測定装置 |
JP5751769B2 (ja) | 2010-07-27 | 2015-07-22 | キヤノン株式会社 | 画像情報取得装置及びその制御方法 |
US20120127557A1 (en) * | 2010-11-19 | 2012-05-24 | Canon Kabushiki Kaisha | Apparatus and method for irradiating a medium |
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2007
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2008
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US9351705B2 (en) | 2009-01-09 | 2016-05-31 | Washington University | Miniaturized photoacoustic imaging apparatus including a rotatable reflector |
WO2011091360A2 (en) * | 2010-01-25 | 2011-07-28 | Washington University | Optical time reversal by ultrasonic encoding in biological tissue |
WO2011091360A3 (en) * | 2010-01-25 | 2011-11-24 | Washington University | Optical time reversal by ultrasonic encoding in biological tissue |
US9234841B2 (en) | 2010-01-25 | 2016-01-12 | Washington University | Optical time reversal by ultrasonic encoding in biological tissue |
US9335605B2 (en) | 2010-01-25 | 2016-05-10 | Washington University | Iteration of optical time reversal by ultrasonic encoding in biological tissue |
US9655527B2 (en) | 2010-04-09 | 2017-05-23 | Washington University | Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography |
US9086365B2 (en) | 2010-04-09 | 2015-07-21 | Lihong Wang | Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography |
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US11137375B2 (en) | 2013-11-19 | 2021-10-05 | California Institute Of Technology | Systems and methods of grueneisen-relaxation photoacoustic microscopy and photoacoustic wavefront shaping |
JP2017040662A (ja) * | 2016-10-31 | 2017-02-23 | 株式会社アクロエッジ | 測定方法 |
US11672426B2 (en) | 2017-05-10 | 2023-06-13 | California Institute Of Technology | Snapshot photoacoustic photography using an ergodic relay |
US11530979B2 (en) | 2018-08-14 | 2022-12-20 | California Institute Of Technology | Multifocal photoacoustic microscopy through an ergodic relay |
US11592652B2 (en) | 2018-09-04 | 2023-02-28 | California Institute Of Technology | Enhanced-resolution infrared photoacoustic microscopy and spectroscopy |
US11369280B2 (en) | 2019-03-01 | 2022-06-28 | California Institute Of Technology | Velocity-matched ultrasonic tagging in photoacoustic flowgraphy |
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Also Published As
Publication number | Publication date |
---|---|
EP2036490B1 (en) | 2015-02-25 |
JP5317449B2 (ja) | 2013-10-16 |
US20090069676A1 (en) | 2009-03-12 |
EP2036490A1 (en) | 2009-03-18 |
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