JP2008546827A - 新規な3−アザ−スピロ[5.5]ウンデカ−8−エン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用 - Google Patents

新規な3−アザ−スピロ[5.5]ウンデカ−8−エン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用 Download PDF

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JP2008546827A
JP2008546827A JP2008518825A JP2008518825A JP2008546827A JP 2008546827 A JP2008546827 A JP 2008546827A JP 2008518825 A JP2008518825 A JP 2008518825A JP 2008518825 A JP2008518825 A JP 2008518825A JP 2008546827 A JP2008546827 A JP 2008546827A
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disorder
aza
spiro
undec
ene
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JP2008546827A5 (enExample
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エリクセン、ビルギット、エル.
ペーターズ、ダン
ニールセン、エルセベット、オステルガード
ポール レッドローブ、ジョン
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ノイロサーチ アクティーゼルスカブ
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    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Addiction (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2008518825A 2005-06-28 2006-06-28 新規な3−アザ−スピロ[5.5]ウンデカ−8−エン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用 Abandoned JP2008546827A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200500959 2005-06-28
US69467905P 2005-06-29 2005-06-29
PCT/EP2006/063633 WO2007000464A1 (en) 2005-06-28 2006-06-28 Novel 3-aza-spiro[5.5]undec-8-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

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JP2008546827A true JP2008546827A (ja) 2008-12-25
JP2008546827A5 JP2008546827A5 (enExample) 2009-08-06

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JP2008518825A Abandoned JP2008546827A (ja) 2005-06-28 2006-06-28 新規な3−アザ−スピロ[5.5]ウンデカ−8−エン誘導体及びモノアミン神経伝達物質再取り込み阻害剤としてのこれらの使用

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EP (1) EP1899301B1 (enExample)
JP (1) JP2008546827A (enExample)
WO (1) WO2007000464A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117924272A (zh) * 2022-10-26 2024-04-26 珠海联邦制药股份有限公司 一种jak抑制剂类药物中间体的合成方法及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA971525B (en) * 1996-02-22 1997-10-21 Neurosearch As Tropane derivatives, their preparation and use.

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EP1899301A1 (en) 2008-03-19
WO2007000464A1 (en) 2007-01-04
EP1899301B1 (en) 2010-09-15

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