JP2008546374A5 - - Google Patents

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Publication number
JP2008546374A5
JP2008546374A5 JP2008512576A JP2008512576A JP2008546374A5 JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5 JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5
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JP
Japan
Prior art keywords
mcp
antibody
human
cells
binding
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008512576A
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English (en)
Japanese (ja)
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JP4975020B2 (ja
JP2008546374A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/019627 external-priority patent/WO2006125202A2/en
Publication of JP2008546374A publication Critical patent/JP2008546374A/ja
Publication of JP2008546374A5 publication Critical patent/JP2008546374A5/ja
Application granted granted Critical
Publication of JP4975020B2 publication Critical patent/JP4975020B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2008512576A 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用 Expired - Fee Related JP4975020B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68265405P 2005-05-19 2005-05-19
US68262005P 2005-05-19 2005-05-19
US60/682,654 2005-05-19
US60/682,620 2005-05-19
PCT/US2006/019627 WO2006125202A2 (en) 2005-05-19 2006-05-19 Anti- mcp-1 antibodies, compositions, methods and uses

Publications (3)

Publication Number Publication Date
JP2008546374A JP2008546374A (ja) 2008-12-25
JP2008546374A5 true JP2008546374A5 (https=) 2012-04-05
JP4975020B2 JP4975020B2 (ja) 2012-07-11

Family

ID=37432201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008512576A Expired - Fee Related JP4975020B2 (ja) 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用

Country Status (20)

Country Link
EP (1) EP1888114B1 (https=)
JP (1) JP4975020B2 (https=)
KR (1) KR100977823B1 (https=)
CN (1) CN101511869B (https=)
AR (1) AR053470A1 (https=)
AU (2) AU2006247034B2 (https=)
BR (1) BRPI0613164A2 (https=)
CA (1) CA2609349C (https=)
CR (1) CR9606A (https=)
EA (1) EA014229B1 (https=)
ES (1) ES2438193T3 (https=)
IL (1) IL187459A0 (https=)
MX (1) MX2007014610A (https=)
NO (1) NO20076563L (https=)
NZ (1) NZ563516A (https=)
PA (1) PA8675801A1 (https=)
PE (2) PE20061444A1 (https=)
TW (1) TW200716174A (https=)
WO (1) WO2006125202A2 (https=)
ZA (1) ZA200711073B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2089383B1 (en) 2006-11-09 2015-09-16 Probiodrug AG 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
US9126987B2 (en) 2006-11-30 2015-09-08 Probiodrug Ag Inhibitors of glutaminyl cyclase
AU2008220785B2 (en) 2007-03-01 2013-02-21 Vivoryon Therapeutics N.V. New use of glutaminyl cyclase inhibitors
JP5667440B2 (ja) 2007-04-18 2015-02-12 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体
AU2008269954A1 (en) * 2007-06-29 2009-01-08 Centocor Ortho Biotech Inc. Anti- MCP-1 antibodies, compositions, methods and uses
ES2533493T3 (es) 2008-08-20 2015-04-10 Probiodrug Ag Anticuerpos dirigidos contra la proteína 1 quimioatrayente de monocitos (MCP-1 N1pE) de piroglutamato
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
JP5688745B2 (ja) 2010-03-10 2015-03-25 プロビオドルグ エージー グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
JP2015520768A (ja) * 2012-05-22 2015-07-23 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド 強皮症の処置用の抗−ccl2抗体
EP2727944A1 (en) * 2012-10-30 2014-05-07 Universitätsklinikum Regensburg Depletion of CCR2-positive monocytes for the treatment of inflammatory conditions in the gastrointestinal system
US10684290B2 (en) 2014-02-18 2020-06-16 Dignity Health LKB1 related diagnostics and treatments of cancer
ES2764840T3 (es) 2015-01-28 2020-06-04 Univ Bordeaux Uso de plerixafor para tratar y/o prevenir exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica
US20200306283A1 (en) 2016-06-22 2020-10-01 William Warren HARLESS Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
IL287220B2 (en) 2019-04-17 2026-03-01 Univ Hiroshima A therapeutic agent for urological cancer characterized by administering an IL-6 inhibitor in combination with a CCR2 inhibitor
MX2022007479A (es) 2019-12-18 2022-06-29 Hoffmann La Roche Anticuerpos anti-ccl2 biespecificos.
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
CA3221735A1 (en) * 2021-06-18 2022-12-22 F. Hoffmann-La Roche Ag Bispecific anti-ccl2 antibodies
CN114990073A (zh) * 2022-05-27 2022-09-02 河南农业大学 一种抗猪ccl2蛋白的单克隆抗体及其制备方法和应用

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KR20050042801A (ko) * 2002-09-12 2005-05-10 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 인간형 항인간 mcp-1 항체 및 그의 항체 단편
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