JP2008546374A5 - - Google Patents

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Publication number
JP2008546374A5
JP2008546374A5 JP2008512576A JP2008512576A JP2008546374A5 JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5 JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5
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JP
Japan
Prior art keywords
mcp
antibody
human
cells
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008512576A
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English (en)
Japanese (ja)
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JP2008546374A (ja
JP4975020B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/019627 external-priority patent/WO2006125202A2/en
Publication of JP2008546374A publication Critical patent/JP2008546374A/ja
Publication of JP2008546374A5 publication Critical patent/JP2008546374A5/ja
Application granted granted Critical
Publication of JP4975020B2 publication Critical patent/JP4975020B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008512576A 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用 Expired - Fee Related JP4975020B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68262005P 2005-05-19 2005-05-19
US68265405P 2005-05-19 2005-05-19
US60/682,654 2005-05-19
US60/682,620 2005-05-19
PCT/US2006/019627 WO2006125202A2 (en) 2005-05-19 2006-05-19 Anti- mcp-1 antibodies, compositions, methods and uses

Publications (3)

Publication Number Publication Date
JP2008546374A JP2008546374A (ja) 2008-12-25
JP2008546374A5 true JP2008546374A5 (enExample) 2012-04-05
JP4975020B2 JP4975020B2 (ja) 2012-07-11

Family

ID=37432201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008512576A Expired - Fee Related JP4975020B2 (ja) 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用

Country Status (20)

Country Link
EP (1) EP1888114B1 (enExample)
JP (1) JP4975020B2 (enExample)
KR (1) KR100977823B1 (enExample)
CN (1) CN101511869B (enExample)
AR (1) AR053470A1 (enExample)
AU (2) AU2006247034B2 (enExample)
BR (1) BRPI0613164A2 (enExample)
CA (1) CA2609349C (enExample)
CR (1) CR9606A (enExample)
EA (1) EA014229B1 (enExample)
ES (1) ES2438193T3 (enExample)
IL (1) IL187459A0 (enExample)
MX (1) MX2007014610A (enExample)
NO (1) NO20076563L (enExample)
NZ (1) NZ563516A (enExample)
PA (1) PA8675801A1 (enExample)
PE (2) PE20110071A1 (enExample)
TW (1) TW200716174A (enExample)
WO (1) WO2006125202A2 (enExample)
ZA (1) ZA200711073B (enExample)

Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
WO2008055945A1 (en) 2006-11-09 2008-05-15 Probiodrug Ag 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
EP2091948B1 (en) 2006-11-30 2012-04-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
CN101668525A (zh) 2007-03-01 2010-03-10 前体生物药物股份公司 谷氨酰胺酰环化酶抑制剂的新用途
US9656991B2 (en) 2007-04-18 2017-05-23 Probiodrug Ag Inhibitors of glutaminyl cyclase
AU2008269954A1 (en) * 2007-06-29 2009-01-08 Centocor Ortho Biotech Inc. Anti- MCP-1 antibodies, compositions, methods and uses
ES2533493T3 (es) 2008-08-20 2015-04-10 Probiodrug Ag Anticuerpos dirigidos contra la proteína 1 quimioatrayente de monocitos (MCP-1 N1pE) de piroglutamato
ES2548913T3 (es) 2009-09-11 2015-10-21 Probiodrug Ag Derivados heterocíclicos como inhibidores de glutaminil ciclasa
WO2011107530A2 (en) 2010-03-03 2011-09-09 Probiodrug Ag Novel inhibitors
CA2789440C (en) 2010-03-10 2020-03-24 Probiodrug Ag Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
JP5945532B2 (ja) 2010-04-21 2016-07-05 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
US8530670B2 (en) 2011-03-16 2013-09-10 Probiodrug Ag Inhibitors
IN2014DN09951A (enExample) * 2012-05-22 2015-08-14 Shire Human Genetic Therapies
EP2727944A1 (en) * 2012-10-30 2014-05-07 Universitätsklinikum Regensburg Depletion of CCR2-positive monocytes for the treatment of inflammatory conditions in the gastrointestinal system
WO2015126898A1 (en) 2014-02-18 2015-08-27 Dignity Health Lkb1 related diagnostics and treatments of cancer
ES2764840T3 (es) 2015-01-28 2020-06-04 Univ Bordeaux Uso de plerixafor para tratar y/o prevenir exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica
WO2018014111A1 (en) 2016-06-22 2018-01-25 Harless William Warren Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neul sialidase inhibitor or a cytokine inhibitor after primary cancer treatment
EP3461819B1 (en) 2017-09-29 2020-05-27 Probiodrug AG Inhibitors of glutaminyl cyclase
MX2021012163A (es) 2019-04-17 2022-01-31 Univ Hiroshima Agente terapeutico para cancer urologico que se caracteriza por ser administrado con un inhibidor de il-6 y un inhibidor de ccr2 en combinacion.
EP4076663A1 (en) 2019-12-18 2022-10-26 F. Hoffmann-La Roche AG Bispecific anti-ccl2 antibodies
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
CN114990073A (zh) * 2022-05-27 2022-09-02 河南农业大学 一种抗猪ccl2蛋白的单克隆抗体及其制备方法和应用

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EP0216846B2 (en) 1985-04-01 1995-04-26 Celltech Limited Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
WO1990005144A1 (en) 1988-11-11 1990-05-17 Medical Research Council Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
US5266491A (en) 1989-03-14 1993-11-30 Mochida Pharmaceutical Co., Ltd. DNA fragment and expression plasmid containing the DNA fragment
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
AU8081491A (en) 1990-06-01 1991-12-31 Cetus Corporation Compositions and methods for identifying biologically active molecules
US5723286A (en) 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
WO1992005258A1 (en) 1990-09-20 1992-04-02 La Trobe University Gene encoding barley enzyme
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE4436420C5 (de) 1994-10-12 2009-04-02 Daimler Ag Mittelkonsole für ein Kraftfahrzeug
US6019968A (en) 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
DE69814428T2 (de) 1997-09-29 2004-05-13 Nektar Therapeutics, San Carlos In verneblern verwendbare, stabilisierte zubereitungen
GB0016138D0 (en) * 2000-06-30 2000-08-23 Novartis Ag Organic compounds
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EP1461300B1 (en) * 2001-11-30 2011-07-27 Biogen Idec MA Inc. Antibodies against monocyte chemotactic proteins
EP1542724A4 (en) * 2002-08-19 2005-10-19 Abgenix Inc ANTIBODIES AGAINST THE MONOCYTE 1 CHIMIOATTRACTIVE PROTEIN (MCP-1) AND USES THEREOF
KR20050042801A (ko) * 2002-09-12 2005-05-10 자이단호진 가가쿠오요비겟세이료호겐쿠쇼 인간형 항인간 mcp-1 항체 및 그의 항체 단편
EP1716181B1 (en) 2004-02-19 2009-12-16 Genentech, Inc. Cdr-repaired antibodies
CA2572289A1 (en) * 2004-06-30 2006-08-17 Centocor, Inc. Anti-mcp-1 antibodies, compositions, methods and uses

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