JP2008546374A5 - - Google Patents

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Publication number
JP2008546374A5
JP2008546374A5 JP2008512576A JP2008512576A JP2008546374A5 JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5 JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008512576 A JP2008512576 A JP 2008512576A JP 2008546374 A5 JP2008546374 A5 JP 2008546374A5
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JP
Japan
Prior art keywords
mcp
antibody
human
cells
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008512576A
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English (en)
Japanese (ja)
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JP2008546374A (ja
JP4975020B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/019627 external-priority patent/WO2006125202A2/en
Publication of JP2008546374A publication Critical patent/JP2008546374A/ja
Publication of JP2008546374A5 publication Critical patent/JP2008546374A5/ja
Application granted granted Critical
Publication of JP4975020B2 publication Critical patent/JP4975020B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2008512576A 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用 Expired - Fee Related JP4975020B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68265405P 2005-05-19 2005-05-19
US68262005P 2005-05-19 2005-05-19
US60/682,620 2005-05-19
US60/682,654 2005-05-19
PCT/US2006/019627 WO2006125202A2 (en) 2005-05-19 2006-05-19 Anti- mcp-1 antibodies, compositions, methods and uses

Publications (3)

Publication Number Publication Date
JP2008546374A JP2008546374A (ja) 2008-12-25
JP2008546374A5 true JP2008546374A5 (enExample) 2012-04-05
JP4975020B2 JP4975020B2 (ja) 2012-07-11

Family

ID=37432201

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008512576A Expired - Fee Related JP4975020B2 (ja) 2005-05-19 2006-05-19 抗mcp−1抗体、組成物、方法および使用

Country Status (20)

Country Link
EP (1) EP1888114B1 (enExample)
JP (1) JP4975020B2 (enExample)
KR (1) KR100977823B1 (enExample)
CN (1) CN101511869B (enExample)
AR (1) AR053470A1 (enExample)
AU (2) AU2006247034B2 (enExample)
BR (1) BRPI0613164A2 (enExample)
CA (1) CA2609349C (enExample)
CR (1) CR9606A (enExample)
EA (1) EA014229B1 (enExample)
ES (1) ES2438193T3 (enExample)
IL (1) IL187459A0 (enExample)
MX (1) MX2007014610A (enExample)
NO (1) NO20076563L (enExample)
NZ (1) NZ563516A (enExample)
PA (1) PA8675801A1 (enExample)
PE (2) PE20110071A1 (enExample)
TW (1) TW200716174A (enExample)
WO (1) WO2006125202A2 (enExample)
ZA (1) ZA200711073B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
WO2008128985A1 (en) 2007-04-18 2008-10-30 Probiodrug Ag Thiourea derivatives as glutaminyl cyclase inhibitors
US20100254992A1 (en) * 2007-06-29 2010-10-07 Anuk Das Anti-mcp-1 antibodies, compositions, methods and uses
ES2533493T3 (es) 2008-08-20 2015-04-10 Probiodrug Ag Anticuerpos dirigidos contra la proteína 1 quimioatrayente de monocitos (MCP-1 N1pE) de piroglutamato
PL2475428T3 (pl) 2009-09-11 2015-12-31 Probiodrug Ag Pochodne heterocykliczne jako inhibitory cyklazy glutaminowej
ES2586231T3 (es) 2010-03-03 2016-10-13 Probiodrug Ag Inhibidores de glutaminil ciclasa
MX2012010470A (es) 2010-03-10 2012-10-09 Probiodrug Ag Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5).
US8541596B2 (en) 2010-04-21 2013-09-24 Probiodrug Ag Inhibitors
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
US20150158942A1 (en) * 2012-05-22 2015-06-11 Shire Human Genetic Therapies, Inc. Anti-ccl2 antibodies for treatment of scleroderma
EP2727944A1 (en) * 2012-10-30 2014-05-07 Universitätsklinikum Regensburg Depletion of CCR2-positive monocytes for the treatment of inflammatory conditions in the gastrointestinal system
CA2934626C (en) 2014-02-18 2023-08-01 Dignity Health Lkb1 related diagnostics and treatments of cancer
DK3050574T3 (da) 2015-01-28 2020-01-20 Univ Bordeaux Anvendelse af plerixafor til behandling og/eller forebyggelse af akutte forværringer af kronisk obstruktiv lungesygdom
US20200306283A1 (en) 2016-06-22 2020-10-01 William Warren HARLESS Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej
AU2020259884A1 (en) 2019-04-17 2021-10-07 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
BR112022012010A2 (pt) 2019-12-18 2022-08-30 Hoffmann La Roche Anticorpos, ácido nucleico isolado, célula hospedeira, formulação farmacêutica, uso do anticorpo, método de produção de um anticorpo, método de tratamento de um indivíduo que tem câncer e método de tratamento de um indivíduo que tem uma doença inflamatória ou autoimune
CN112358547A (zh) * 2020-09-30 2021-02-12 浙江大学 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用
JP2024523034A (ja) * 2021-06-18 2024-06-25 エフ. ホフマン-ラ ロシュ アーゲー 二重特異性抗ccl2抗体
CN114990073A (zh) * 2022-05-27 2022-09-02 河南农业大学 一种抗猪ccl2蛋白的单克隆抗体及其制备方法和应用

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GB2183662B (en) 1985-04-01 1989-01-25 Celltech Ltd Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
FI903489A7 (fi) 1988-11-11 1990-07-10 Medical Res Council Yhden osan sisältävät ligandit, näitä ligandeja sisältävät reseptorit, menetelmiä niiden valmistamiseksi sekä ligandien ja reseptorien käytt ö
US5266491A (en) 1989-03-14 1993-11-30 Mochida Pharmaceutical Co., Ltd. DNA fragment and expression plasmid containing the DNA fragment
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
ES2109945T3 (es) 1990-06-01 1998-02-01 Chiron Corp Composiciones y procedimientos para identificar moleculas biologicamente activas.
US5723286A (en) 1990-06-20 1998-03-03 Affymax Technologies N.V. Peptide library and screening systems
WO1992005258A1 (en) 1990-09-20 1992-04-02 La Trobe University Gene encoding barley enzyme
US5270170A (en) 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE4436420C5 (de) 1994-10-12 2009-04-02 Daimler Ag Mittelkonsole für ein Kraftfahrzeug
US6019968A (en) 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
ATE248583T1 (de) 1997-09-29 2003-09-15 Nektar Therapeutics In dosierinhalatoren verwendbare, stabilisierte zubereitungen
GB0016138D0 (en) * 2000-06-30 2000-08-23 Novartis Ag Organic compounds
WO2003002019A2 (en) 2001-06-27 2003-01-09 Salviac Limited A catheter
EP2990394A1 (en) * 2001-11-30 2016-03-02 Biogen MA Inc. Antibodies against monocyte chemotactic proteins
EP1542724A4 (en) * 2002-08-19 2005-10-19 Abgenix Inc ANTIBODIES AGAINST THE MONOCYTE 1 CHIMIOATTRACTIVE PROTEIN (MCP-1) AND USES THEREOF
CA2497804A1 (en) * 2002-09-12 2004-03-25 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Human anti-human mcp-1 antibody and fragment of said antibody
EP2168986A3 (en) 2004-02-19 2010-07-28 Genentech, Inc. CDR-repaired antibodies
US7371825B2 (en) * 2004-06-30 2008-05-13 Centocor, Inc. Anti-MCP-1 antibodies, compositions, methods and uses

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