JP2008544248A5 - - Google Patents
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- Publication number
- JP2008544248A5 JP2008544248A5 JP2008516784A JP2008516784A JP2008544248A5 JP 2008544248 A5 JP2008544248 A5 JP 2008544248A5 JP 2008516784 A JP2008516784 A JP 2008516784A JP 2008516784 A JP2008516784 A JP 2008516784A JP 2008544248 A5 JP2008544248 A5 JP 2008544248A5
- Authority
- JP
- Japan
- Prior art keywords
- data
- binding
- interaction
- affinity
- steady state
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000027455 binding Effects 0.000 claims 33
- 230000003993 interaction Effects 0.000 claims 19
- 238000000034 method Methods 0.000 claims 14
- 238000010494 dissociation reaction Methods 0.000 claims 12
- 230000005593 dissociations Effects 0.000 claims 12
- 239000013626 chemical specie Substances 0.000 claims 7
- 238000001514 detection method Methods 0.000 claims 5
- 230000009149 molecular binding Effects 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- 238000002790 cross-validation Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 2
- 238000004458 analytical method Methods 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 238000003908 quality control method Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68981905P | 2005-06-13 | 2005-06-13 | |
| SE0501335-4 | 2005-06-13 | ||
| SE0501335 | 2005-06-13 | ||
| US60/689,819 | 2005-06-13 | ||
| PCT/SE2006/000679 WO2006135309A2 (en) | 2005-06-13 | 2006-06-12 | Method and system for affinity analysis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008544248A JP2008544248A (ja) | 2008-12-04 |
| JP2008544248A5 true JP2008544248A5 (enrdf_load_stackoverflow) | 2009-07-02 |
| JP5052509B2 JP5052509B2 (ja) | 2012-10-17 |
Family
ID=37532718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516784A Expired - Fee Related JP5052509B2 (ja) | 2005-06-13 | 2006-06-12 | アフィニティ分析法及びシステム |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1893978A4 (enrdf_load_stackoverflow) |
| JP (1) | JP5052509B2 (enrdf_load_stackoverflow) |
| WO (1) | WO2006135309A2 (enrdf_load_stackoverflow) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008088288A1 (en) | 2007-01-18 | 2008-07-24 | Ridgeview Instruments Ab | Method for the quality control of molecules or targets |
| CN101261226B (zh) * | 2007-03-08 | 2010-12-08 | 北京宏荣博曼生物科技有限责任公司 | 一种基于聚乙二醇的表面等离子共振仪芯片 |
| GB2447696A (en) | 2007-03-23 | 2008-09-24 | Univ Exeter | Photonic biosensor arrays |
| MX2011001117A (es) | 2008-08-27 | 2011-03-02 | Hoffmann La Roche | Metodo para cribado de anticuerpo de alta afinidad. |
| KR101484375B1 (ko) | 2009-08-25 | 2015-01-19 | 에프. 호프만-라 로슈 아게 | 속도 인자 |
| DK2507618T3 (en) | 2009-11-30 | 2015-07-27 | Ge Healthcare Bio Sciences Ab | Method and system for interaction analysis |
| EP2507619B1 (en) * | 2009-11-30 | 2018-04-04 | GE Healthcare Bio-Sciences AB | Method and system for binding behavior analysis |
| EP2912060B1 (en) | 2012-10-29 | 2019-12-25 | The University of North Carolina at Chapel Hill | Compositions and methods for inhibiting pathogen infection |
| US10829543B2 (en) | 2012-10-29 | 2020-11-10 | The University Of North Carolina At Chapel Hill | Compositions and methods for inhibiting pathogen infection |
| US11022609B2 (en) * | 2013-11-19 | 2021-06-01 | Ge Healthcare Bio-Sciences Ab | Method for determining interaction kinetics with rapid dissociation |
| CN106471372B (zh) * | 2014-01-29 | 2019-10-11 | 通用电气健康护理生物科学股份公司 | 用于相互作用分析的方法和系统 |
| WO2017083681A1 (en) * | 2015-11-13 | 2017-05-18 | The University Or North Carolina At Chapel Hill | Optimized crosslinkers for trapping a target on a substrate |
| GB201914063D0 (en) * | 2019-09-30 | 2019-11-13 | Ge Healthcare Bio Sciences Ab | Method for classifying monitoring results from an analytical sensor system arranged to monitor molecular interactions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE504507C2 (sv) * | 1993-05-24 | 1997-02-24 | Pharmacia Biosensor Ab | Sätt att bestämma bindningsegenskaper hos ligander med låg molekylvikt |
| WO2003056296A2 (en) * | 2001-08-30 | 2003-07-10 | Klakamp Scott L | Improved methods for determining binding affinities |
| JP4406287B2 (ja) * | 2002-03-27 | 2010-01-27 | ジーイー・ヘルスケア・バイオ−サイエンシーズ・アーベー | 応答曲線の質の制御を包含する、分子結合相互作用の検出のための方法、システムおよびコンピュータプログラム |
| WO2005029077A1 (en) * | 2003-09-24 | 2005-03-31 | Biacore Ab | Method and system for molecular interaction analysis |
-
2006
- 2006-06-12 JP JP2008516784A patent/JP5052509B2/ja not_active Expired - Fee Related
- 2006-06-12 EP EP06747872.7A patent/EP1893978A4/en not_active Withdrawn
- 2006-06-12 WO PCT/SE2006/000679 patent/WO2006135309A2/en active Application Filing
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