JP2008543877A - Ｌｋｋｔｅｔおよび／またはｌｋｋｔｎｔ組成物および組織の悪化、傷害または損傷を処置または予防するための方法 - Google Patents
Ｌｋｋｔｅｔおよび／またはｌｋｋｔｎｔ組成物および組織の悪化、傷害または損傷を処置または予防するための方法 Download PDFInfo
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- PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- MSXHSNHNTORCAW-GGLLEASOSA-M sodium;(2s,3s,4s,5r,6s)-3,4,5,6-tetrahydroxyoxane-2-carboxylate Chemical compound [Na+].O[C@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O MSXHSNHNTORCAW-GGLLEASOSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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- 150000005846 sugar alcohols Chemical class 0.000 description 1
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- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- PAPBSGBWRJIAAV-UHFFFAOYSA-N ε-Caprolactone Chemical compound O=C1CCCCCO1 PAPBSGBWRJIAAV-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2006/023758 WO2006138707A1 (en) | 2005-06-17 | 2006-06-19 | Lkktet and/or lkktnt compositions and methods for treating or preventing tissue deterioration, injury or damage |
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| JP2008517207A Pending JP2008543878A (ja) | 2005-06-17 | 2006-06-19 | 凍結乾燥したかまたは凍結乾燥させることができる形態であるｌｋｋｔｅｔおよび／またはｌｋｋｔｎｔペプチド組成物 |
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| JP2008517208A Withdrawn JP2008543879A (ja) | 2005-06-17 | 2006-06-19 | Ｌｋｋｔｅｔおよび／またはｌｋｋｔｎｔペプチド組成物ならびに方法 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2018531905A (ja) * | 2015-10-06 | 2018-11-01 | ジー−トゥリー・ビーエヌティ・カンパニー・リミテッドＧ−Ｔｒｅｅｂｎｔ Ｃｏ．， Ｌｔｄ． | チモシンベータ４を含む眼科用製剤の製造方法 |
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|---|---|---|---|---|
| MX2010010177A (es) * | 2008-03-17 | 2012-08-23 | Regenerx Biopharmaceuticals | Fragmentos de beta timosina mejorada. |
| CN101297965B (zh) * | 2008-06-16 | 2011-01-05 | 浙江省中医药研究院 | 胸腺肽β4在制备防治支气管哮喘药物中的应用 |
| EP2485765A2 (en) * | 2009-10-09 | 2012-08-15 | Board Of Regents The University Of Texas System | Photokinetic ocular drug delivery methods and apparatus |
| WO2012126047A1 (en) * | 2011-03-18 | 2012-09-27 | Adistem Ltd | Agent and method for treating pain and reducing inflammation |
| CN104271142B (zh) | 2012-03-01 | 2017-07-04 | 福斯特斯特林研究公司 | 含有α连接蛋白C‑末端(ACT)肽的局部凝胶 |
| EP2698162A1 (en) * | 2012-08-15 | 2014-02-19 | Credentis AG | Method for producing a composition for treating a tooth lesion |
| PL3065756T3 (pl) | 2013-11-07 | 2019-07-31 | Dr. August Wolff Gmbh & Co. Kg Arzneimittel | Stabilnie przechowywane liofilizowane formulacje tripeptydowe |
| US10302658B2 (en) | 2014-03-12 | 2019-05-28 | University Of Virginia Patent Foundation | Compositions and methods for treating eye infections and disease |
| JP6634451B2 (ja) | 2014-10-22 | 2020-01-22 | ジー−トゥリー・ビーエヌティ・カンパニー・リミテッドＧ−Ｔｒｅｅｂｎｔ Ｃｏ．， Ｌｔｄ． | チモシンβ４を含有する組成物、およびそれを含む医薬製剤 |
| MA41299A (fr) * | 2014-12-30 | 2017-11-07 | Axim Biotechnologies Inc | Solutions ophtalmiques pour le traitement du glaucome et de la conjonctivite |
| KR20170021667A (ko) | 2015-08-18 | 2017-02-28 | 주식회사 지트리비앤티 | 티모신 β4를 유효성분으로 포함하는 신경영양성각막염 치료용 조성물 |
| US9867868B2 (en) * | 2015-08-18 | 2018-01-16 | G-Treebnt Co., Ltd. | Pharmaceutical composition for treating or preventing corneal wound comprising thymosin β4 and citric acid |
| KR102488796B1 (ko) * | 2016-07-18 | 2023-01-13 | 리젠트리 엘엘씨 | 안구 건조증 치료 방법 |
| KR102115158B1 (ko) | 2016-11-29 | 2020-05-26 | 주식회사 지트리파마슈티컬 | 티모신 베타 4 를 함유하는 제형 |
| US20190381136A1 (en) * | 2017-02-21 | 2019-12-19 | Tearsolutions, Inc. | Stable peptide compositions |
| KR102340750B1 (ko) * | 2017-03-03 | 2021-12-21 | 에이치엘비테라퓨틱스 주식회사 | 티모신 베타 4를 유효성분으로 포함하는 안정화된 외용 제제 |
| KR101910908B1 (ko) * | 2017-06-14 | 2018-10-24 | (주)휴온스 | Gly-Tβ4 (Gly-티모신β4)을 함유하는 안구건조증 치료용 약학적 조성물 |
| US10342824B2 (en) | 2017-07-17 | 2019-07-09 | Dr. Marlowe's Weight Loss Institute, P.L.L.C. | Supplement for treating side effects of medications which cause metabolic acidosis |
| AU2018372396A1 (en) * | 2017-11-24 | 2020-06-25 | HLB Therapeutics Co., Ltd. | Composition for promoting goblet cell proliferation or mucin secretion comprising thymosin beta 4 or derivative thereof as active ingredient |
| JP2023546757A (ja) | 2020-10-22 | 2023-11-07 | シークエル・バイオ・インコーポレイテッド | ペプチド製剤および眼科におけるその使用 |
| WO2024006653A2 (en) * | 2022-07-01 | 2024-01-04 | Tearsolutions, Inc. | Stable peptide compositions and methods of use thereof for treatment of moderate/severe dry eye-related ocular symptoms |
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| WO2002074193A2 (en) * | 2001-03-15 | 2002-09-26 | Regenerx, Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN ss4 (Tss4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
| US20040220111A1 (en) * | 1998-07-30 | 2004-11-04 | United States Of America As Represented By The Secretary Of Health | Thymosin beta 4 compositions |
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| US4444757A (en) * | 1981-11-16 | 1984-04-24 | Research Corporation | Use of thymosin as an anti-diabetes and anti-hypertensive disease agent |
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| FR2647675B1 (fr) | 1989-06-05 | 1994-05-20 | Sanofi | Utilisation d'un derive de la statine dans le traitement des affections oculaires |
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| AU2001292881A1 (en) * | 2000-09-20 | 2002-04-02 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| EP1427432A4 (en) * | 2001-08-29 | 2008-01-23 | Regenerx Biopharmaceuticals | METHOD FOR HEALING OR PREVENTING IGNITION, DAMAGE, AND OTHER CHANGES ARISING BEFORE, DURING, OR DIRECTLY TO A MYOKARDIN FARM, WITH THYMOSINE BETA 4, ANALOGUE, ISOFORMS AND OTHER DERIVATIVES |
| WO2003073911A2 (en) * | 2002-02-28 | 2003-09-12 | Georgetown University | Method and composition for detection and treatment of breast cancer |
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2006
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- 2006-06-19 WO PCT/US2006/023758 patent/WO2006138707A1/en not_active Ceased
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- 2006-06-19 AU AU2006261155A patent/AU2006261155A1/en not_active Abandoned
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| JP2018531905A (ja) * | 2015-10-06 | 2018-11-01 | ジー−トゥリー・ビーエヌティ・カンパニー・リミテッドＧ−Ｔｒｅｅｂｎｔ Ｃｏ．， Ｌｔｄ． | チモシンベータ４を含む眼科用製剤の製造方法 |
| JP2020183391A (ja) * | 2015-10-06 | 2020-11-12 | ジー−トゥリー・ビーエヌティ・カンパニー・リミテッドＧ−Ｔｒｅｅｂｎｔ Ｃｏ．， Ｌｔｄ． | チモシンベータ４を含む眼科用製剤の製造方法 |
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