JP2008542219A5 - - Google Patents

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Publication number
JP2008542219A5
JP2008542219A5 JP2008512757A JP2008512757A JP2008542219A5 JP 2008542219 A5 JP2008542219 A5 JP 2008542219A5 JP 2008512757 A JP2008512757 A JP 2008512757A JP 2008512757 A JP2008512757 A JP 2008512757A JP 2008542219 A5 JP2008542219 A5 JP 2008542219A5
Authority
JP
Japan
Prior art keywords
phenyl
pyrimidin
compound
ylamino
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008512757A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008542219A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/004924 external-priority patent/WO2006125616A2/en
Publication of JP2008542219A publication Critical patent/JP2008542219A/ja
Publication of JP2008542219A5 publication Critical patent/JP2008542219A5/ja
Pending legal-status Critical Current

Links

JP2008512757A 2005-05-25 2006-05-24 疼痛処置法 Pending JP2008542219A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68434505P 2005-05-25 2005-05-25
PCT/EP2006/004924 WO2006125616A2 (en) 2005-05-25 2006-05-24 Pyrimidine-based cdk inhibitors for treating pain

Publications (2)

Publication Number Publication Date
JP2008542219A JP2008542219A (ja) 2008-11-27
JP2008542219A5 true JP2008542219A5 (https=) 2009-07-09

Family

ID=36940712

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008512757A Pending JP2008542219A (ja) 2005-05-25 2006-05-24 疼痛処置法

Country Status (4)

Country Link
US (1) US20090221581A1 (https=)
EP (1) EP1901747A2 (https=)
JP (1) JP2008542219A (https=)
WO (1) WO2006125616A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1763526B1 (en) * 2004-06-28 2009-06-24 Bayer Schering Pharma AG 4,6-disubstituted pyrimidines and their use as protein kinase inhibitors
US20080188524A1 (en) * 2006-10-25 2008-08-07 Martin Augustin Methods of treating pain
WO2008065155A1 (en) * 2006-11-30 2008-06-05 Ingenium Pharmaceuticals Gmbh Cdk inhibitors for treating pain
JP5566880B2 (ja) * 2007-04-24 2014-08-06 インゲニウム ファーマシューティカルズ ジーエムビーエイチ プロテインキナーゼの阻害剤としての４，６−二置換アミノピリミジン誘導体
WO2008129070A1 (en) * 2007-04-24 2008-10-30 Ingenium Pharmaceuticals Gmbh Inhibitors of protein kinases
US8389521B2 (en) * 2007-04-24 2013-03-05 Ingenium Pharmaceuticals Gmbh Inhibitors of protein kinases
WO2008132138A1 (en) * 2007-04-25 2008-11-06 Ingenium Pharmaceuticals Gmbh Derivatives of 4,6-disubstituted aminopyrimidines
CA2693588C (en) * 2007-07-13 2015-11-17 Icagen, Inc. Sodium channel inhibitors
AU2008309517B2 (en) * 2007-10-12 2013-03-14 Astrazeneca Ab Inhibitors of protein kinases
HU0900798D0 (en) 2009-12-21 2010-03-01 Vichem Chemie Kutato Kft 4-phenylamino-pyrimidine derivatives having protein kinase inhibitor activity
EP2681193B1 (en) * 2011-03-02 2016-01-06 Lead Discovery Center GmbH Pharmaceutically active disubstituted pyridine derivatives
JP6378171B2 (ja) 2012-04-24 2018-08-22 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｄｎａ−ｐｋ阻害剤
BR112015003655A2 (pt) 2012-08-23 2017-07-04 Virostatics Srl composto; uso de um composto; e composição farmacêutica
SI3527563T1 (sl) 2013-03-12 2022-01-31 Vertex Pharmaceuticals Incorporated Inhibitorji DNA-PK
RU2675270C2 (ru) 2013-10-17 2018-12-18 Вертекс Фармасьютикалз Инкорпорейтед Сокристаллы и содержащие их фармацевтические композиции
PT3057959T (pt) * 2013-10-17 2018-06-04 Vertex Pharma Inibidores de adn-pk
ES2821962T3 (es) * 2015-11-13 2021-04-28 Dae Woong Pharma Bloqueador de canales de sodio
RU2758669C2 (ru) 2016-09-27 2021-11-01 Вертекс Фармасьютикалз Инкорпорейтед Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк
BR112020007549A2 (pt) * 2017-10-17 2020-09-24 Merck Patent Gmbh compostos inibidores de pirimidina tbk/ikképsilon e uso dos mesmos
US12157730B2 (en) 2019-03-19 2024-12-03 Voronoi Inc. Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component
AU2020240382B2 (en) 2019-03-19 2022-08-25 Voronoi Inc. Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component
EP4194450A4 (en) * 2020-08-07 2024-10-30 Pharmablock Sciences (Nanjing), Inc. CDK9 INHIBITOR AND USE THEREOF

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9319568D0 (en) * 1993-09-22 1993-11-10 Euro Celtique Sa Pharmaceutical compositions and usages
EP1373257B9 (en) * 2001-03-29 2008-10-15 Vertex Pharmaceuticals Incorporated Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases
US20040106647A1 (en) * 2002-06-28 2004-06-03 Schneider Michael D. Modulators of Cdk9 as a therapeutic target in cardiac hypertrophy
US7576085B2 (en) * 2002-09-23 2009-08-18 Schering Corporation Imidazopyrazines as cyclin dependent kinase inhibitors
CA2503715A1 (en) * 2002-10-30 2004-05-21 Merck & Co., Inc. Kinase inhibitors
AU2004259346A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
WO2005026129A1 (en) * 2003-09-15 2005-03-24 Gpc Biotech Ag Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases
TW200614993A (en) * 2004-06-11 2006-05-16 Akzo Nobel Nv 4-phenyl-pyrimidine-2-carbonitrile derivatives

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