JP2008541745A5 - - Google Patents

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Publication number
JP2008541745A5
JP2008541745A5 JP2008514036A JP2008514036A JP2008541745A5 JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5 JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5
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JP
Japan
Prior art keywords
formulation
dson
transfection
cells
transfection agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008514036A
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English (en)
Japanese (ja)
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JP2008541745A (ja
JP5371424B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/006340 external-priority patent/WO2006128739A1/en
Publication of JP2008541745A publication Critical patent/JP2008541745A/ja
Publication of JP2008541745A5 publication Critical patent/JP2008541745A5/ja
Application granted granted Critical
Publication of JP5371424B2 publication Critical patent/JP5371424B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008514036A 2005-06-01 2006-06-01 Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用 Expired - Fee Related JP5371424B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68601005P 2005-06-01 2005-06-01
US60/686,010 2005-06-01
PCT/EP2006/006340 WO2006128739A1 (en) 2005-06-01 2006-06-01 Oligonucleotides for rna interference and biological applications thereof

Publications (3)

Publication Number Publication Date
JP2008541745A JP2008541745A (ja) 2008-11-27
JP2008541745A5 true JP2008541745A5 (enExample) 2009-07-09
JP5371424B2 JP5371424B2 (ja) 2013-12-18

Family

ID=37075816

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008514036A Expired - Fee Related JP5371424B2 (ja) 2005-06-01 2006-06-01 Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用

Country Status (6)

Country Link
US (2) US8802640B2 (enExample)
EP (1) EP1888749B1 (enExample)
JP (1) JP5371424B2 (enExample)
CN (1) CN101213300B (enExample)
DK (1) DK1888749T3 (enExample)
WO (1) WO2006128739A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888749B1 (en) 2005-06-01 2014-10-15 Polyplus Transfection Oligonucleotides for rna interference and biological applications thereof
EP4082551A1 (en) * 2006-08-08 2022-11-02 Rheinische Friedrich-Wilhelms-Universität Bonn Structure and use of 5' phosphate oligonucleotides
JP5744513B2 (ja) 2007-04-17 2015-07-08 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 肺送達のための核酸微小粒子
EP2297323A1 (en) 2008-05-21 2011-03-23 Hartmann, Gunther 5' triphosphate oligonucleotide with blunt end and uses thereof
EP2508530A1 (en) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Purification of triphosphorylated oligonucleotides using capture tags
EP2712870A1 (en) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Novel RIG-I ligands and methods for producing them
ES2727078T3 (es) * 2014-03-20 2019-10-14 Oommen Varghese Moléculas de ácido ribonucleico pequeño de interferencia mejoradas
WO2016110691A1 (en) * 2015-01-06 2016-07-14 The University Court Of The University Of Aberdeen Enhanced rnai mediated gene regulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US20070026394A1 (en) * 2000-02-11 2007-02-01 Lawrence Blatt Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
US20030212022A1 (en) * 2001-03-23 2003-11-13 Jean-Marie Vogel Compositions and methods for gene therapy
PT1309726E (pt) 2000-03-30 2010-03-08 Whitehead Biomedical Inst Mediadores de interferência por rna específicos de sequência de rna
KR100909681B1 (ko) 2000-12-01 2009-07-29 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. Ｒｎａ 간섭을 매개하는 작은 ｒｎａ 분자
EP1888749B1 (en) 2005-06-01 2014-10-15 Polyplus Transfection Oligonucleotides for rna interference and biological applications thereof

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