JP2008538076A - 光学活性アルコールの製造方法 - Google Patents

光学活性アルコールの製造方法 Download PDF

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Publication number
JP2008538076A
JP2008538076A JP2008500175A JP2008500175A JP2008538076A JP 2008538076 A JP2008538076 A JP 2008538076A JP 2008500175 A JP2008500175 A JP 2008500175A JP 2008500175 A JP2008500175 A JP 2008500175A JP 2008538076 A JP2008538076 A JP 2008538076A
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JP
Japan
Prior art keywords
enzyme
formula
sequence
nucleic acid
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2008500175A
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English (en)
Japanese (ja)
Inventor
スチュールマー，ライナー
ドイヴェル，ユールゲン
ケセラー，マリア
アハッツ，ブリジット
ブリュエル，ミヒャエル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JP2008538076A publication Critical patent/JP2008538076A/ja
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2008500175A 2005-03-07 2006-03-03 光学活性アルコールの製造方法 Ceased JP2008538076A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510010804 DE102005010804A1 (de) 2005-03-07 2005-03-07 Verfahren zur Herstellung optisch aktiver Alkohole
PCT/EP2006/060452 WO2006094945A2 (de) 2005-03-07 2006-03-03 Verfahren zur herstellung optisch aktiver alkohole durch enzymatische reduktion

Publications (1)

Publication Number Publication Date
JP2008538076A true JP2008538076A (ja) 2008-10-09

Family

ID=36603441

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008500175A Ceased JP2008538076A (ja) 2005-03-07 2006-03-03 光学活性アルコールの製造方法

Country Status (5)

Country Link
EP (1) EP1863918A2 (zh)
JP (1) JP2008538076A (zh)
CN (1) CN101171339A (zh)
DE (1) DE102005010804A1 (zh)
WO (1) WO2006094945A2 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2377907T3 (es) * 2007-06-20 2012-04-03 Basf Se Procedimiento para la obtención de alcoholes con actividad óptica bajo empleo de una dehidrogenasa de Azoarcus sp. EbN1
ES2663272T3 (es) 2008-09-17 2018-04-11 Siegfried Ag Procedimiento para la preparación de L-fenilefrina mediante uso de una alcoholdeshidrogenasa
MX2011006464A (es) 2008-12-17 2011-09-15 Basf Se Biocatalizadores mejorados para la fabricacion de alcohol duloxetina.
PL2445890T3 (pl) 2009-06-22 2016-02-29 Sk Biopharmaceuticals Co Ltd Sposób wytwarzania estru (R)-1-arylo-2-tetrazoliloetylowego kwasu karbaminowego
US8404461B2 (en) 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
EP2640835B1 (de) 2010-11-17 2019-05-22 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
DE102012017026A1 (de) 2012-08-28 2014-03-06 Forschungszentrum Jülich GmbH Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
WO2014086702A2 (de) 2012-12-03 2014-06-12 Basf Se Enzymatische reduktion von hydroxymethylfurfuralen
WO2017140909A1 (de) 2016-02-19 2017-08-24 Basf Se Enzymatische zyklisierung von homofarnesylsäure
EP3775220A1 (en) 2018-03-29 2021-02-17 Firmenich SA Method for producing vanillin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
DE60315958D1 (de) * 2002-03-18 2007-10-11 Biocatalytics Inc Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur
DE10315760A1 (de) * 2003-04-07 2004-10-21 Basf Ag L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen
DE10327454A1 (de) * 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata
DE10345772A1 (de) * 2003-10-01 2005-04-21 Basf Ag Verfahren zur Herstellung von 3-Methylamino-1-(thien-2-yl)-propan-1-ol
DE102004022686A1 (de) * 2004-05-05 2005-11-24 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole

Also Published As

Publication number Publication date
DE102005010804A1 (de) 2006-09-14
WO2006094945A2 (de) 2006-09-14
WO2006094945A3 (de) 2007-03-15
EP1863918A2 (de) 2007-12-12
CN101171339A (zh) 2008-04-30

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Effective date: 20090512

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Effective date: 20090609