JP2008536867A5 - - Google Patents

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Publication number
JP2008536867A5
JP2008536867A5 JP2008506778A JP2008506778A JP2008536867A5 JP 2008536867 A5 JP2008536867 A5 JP 2008536867A5 JP 2008506778 A JP2008506778 A JP 2008506778A JP 2008506778 A JP2008506778 A JP 2008506778A JP 2008536867 A5 JP2008536867 A5 JP 2008536867A5
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JP
Japan
Prior art keywords
substituted
unsubstituted
methoxy
pyridin
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008506778A
Other languages
English (en)
Japanese (ja)
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JP2008536867A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/014194 external-priority patent/WO2006113498A2/en
Publication of JP2008536867A publication Critical patent/JP2008536867A/ja
Publication of JP2008536867A5 publication Critical patent/JP2008536867A5/ja
Pending legal-status Critical Current

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JP2008506778A 2005-04-14 2006-04-14 増殖疾患を処置する際に有用なｈｓｐ９０インヒビターとしての２−アミノ−キナゾリン−５−オン Pending JP2008536867A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67166205P 2005-04-14 2005-04-14
PCT/US2006/014194 WO2006113498A2 (en) 2005-04-14 2006-04-14 2-amino-quinaz0lin-5-ones as hsp90 inhibitors useful in treating proliferation diseases

Publications (2)

Publication Number Publication Date
JP2008536867A JP2008536867A (ja) 2008-09-11
JP2008536867A5 true JP2008536867A5 (https=) 2009-06-04

Family

ID=37110373

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008506778A Pending JP2008536867A (ja) 2005-04-14 2006-04-14 増殖疾患を処置する際に有用なｈｓｐ９０インヒビターとしての２−アミノ−キナゾリン−５−オン

Country Status (12)

Country Link
US (1) US20070027150A1 (https=)
EP (1) EP1885701A2 (https=)
JP (1) JP2008536867A (https=)
KR (1) KR20080006614A (https=)
CN (1) CN101198596A (https=)
AU (1) AU2006236557A1 (https=)
BR (1) BRPI0609309A2 (https=)
CA (1) CA2604942A1 (https=)
MX (1) MX2007012836A (https=)
RU (1) RU2007142007A (https=)
TW (1) TW200718689A (https=)
WO (1) WO2006113498A2 (https=)

Families Citing this family (25)

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Publication number Priority date Publication date Assignee Title
JO2783B1 (en) * 2005-09-30 2014-03-15 نوفارتيس ايه جي Compounds 2-Amino-7, 8-dihydro-6H-Bayredo (3,4-D) Pyrimidine-5-Ones
AU2007296745B2 (en) 2006-09-11 2011-12-01 Curis, Inc. Quinazoline based EGFR inhibitors
CL2007002994A1 (es) * 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
CN101225083A (zh) * 2007-01-16 2008-07-23 北京摩力克科技有限公司 四氢喹唑啉酮类化合物及其用于制备治疗和预防病毒性疾病的药物的用途
WO2008132211A1 (en) * 2007-05-01 2008-11-06 Novartis Ag Amino-quinazolinone derivatives for use as radiotracers and imaging agents
EP2155681B1 (en) * 2007-05-17 2018-05-02 Athenex, Inc. Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
GB2449293A (en) * 2007-05-17 2008-11-19 Evotec Compounds having Hsp90 inhibitory activity
EP2190287B1 (en) 2007-09-10 2014-10-29 Curis, Inc. Tartrate salts or complexes of quinazoline based egfr inhibitors containing a zinc binding moiety
TW200920357A (en) * 2007-09-10 2009-05-16 Curis Inc HSP90 inhibitors containing a zinc binding moiety
US8119616B2 (en) 2007-09-10 2012-02-21 Curis, Inc. Formulation of quinazoline based EGFR inhibitors containing a zinc binding moiety
TW200922595A (en) * 2007-10-12 2009-06-01 Novartis Ag Organic compounds
MX2010006092A (es) * 2007-12-07 2010-07-05 Celgene Corp Biomarcadores para monitorear el tratamiento mediante compuestos de quinazolinona.
ES2475206T3 (es) 2008-02-01 2014-07-10 Takeda Pharmaceutical Company Limited Derivados de oxima como inhibidores de HSP90
LT5623B (lt) 2008-04-30 2010-01-25 Biotechnologijos Institutas, , 5-aril-4-(5-pakeistieji 2,4-dihidroksifenil)-1,2,3-tiadiazolai kaip hsp90 šaperono slopikliai ir tarpiniai junginiai jiems gauti
US20110281908A1 (en) * 2008-10-06 2011-11-17 Emory University Aminoquinoline Derived Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use
DE102008061214A1 (de) * 2008-12-09 2010-06-10 Merck Patent Gmbh Chinazolinamidderivate
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
FR2949467B1 (fr) 2009-09-03 2011-11-25 Sanofi Aventis Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation
CN101735119B (zh) * 2009-12-12 2013-03-27 浙江工业大学 一种三酮类化合物的合成方法
US8481459B2 (en) * 2010-06-14 2013-07-09 Academia Sinica Chemical inhibitors of ethylene biosynthesis
ITTO20111013A1 (it) 2011-11-03 2013-05-04 Dac Srl Composti farmaceutici
US9348490B2 (en) * 2012-09-14 2016-05-24 Ca, Inc. User interface with configuration, registration, and runtime selection of views
CN103333123B (zh) * 2013-07-17 2015-03-11 温州医科大学附属第二医院 一种二氢喹唑啉酮化合物的脱卤方法
EP3628264B1 (en) * 2015-03-17 2024-10-16 Intuitive Surgical Operations, Inc. Systems and methods for rendering onscreen identification of instruments in a teleoperational medical system
EP3459939A1 (en) * 2017-09-26 2019-03-27 Pragma Therapeutics Novel heterocyclic compounds as modulators of mglur7

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4723115B2 (ja) * 2001-05-23 2011-07-13 日本化薬株式会社 アデニル酸シクラーゼ５型阻害剤
CA2524221A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
WO2004113335A2 (en) * 2003-06-20 2004-12-29 Chiron Corporation Pyridino[1,2-a]pyrimidin-4-one compounds as anticancer agents
KR20060070572A (ko) * 2003-09-18 2006-06-23 콘포마 세러퓨틱스 코포레이션 Ｈｓｐ90-저해제로서의 신규 헤테로시클릭 화합물
AU2005266494B2 (en) * 2004-07-27 2009-09-10 Novartis Ag Inhibitors of Hsp90
AR050084A1 (es) * 2004-07-27 2006-09-27 Novartis Ag Derivados de bencimidazolona como inhibidores de hsp90

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