JP2008535826A - 高親和性ｈｉｖｔ細胞レセプター - Google Patents
高親和性ｈｉｖｔ細胞レセプター Download PDFInfo
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/70503—Immunoglobulin superfamily
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
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- Molecular Biology (AREA)
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GB0506760A GB0506760D0 (en) | 2005-04-01 | 2005-04-01 | High affinity HIV TCRS |
| GB0516487A GB0516487D0 (en) | 2005-08-10 | 2005-08-10 | High affinity HIV T cell receptors |
| PCT/GB2006/001147 WO2006103429A2 (en) | 2005-04-01 | 2006-03-29 | High affinity hiv t cell receptors |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2012049174A Division JP5612623B2 (ja) | 2005-04-01 | 2012-03-06 | 高親和性ｈｉｖｔ細胞レセプター |
| JP2014094723A Division JP5885220B2 (ja) | 2005-04-01 | 2014-05-01 | 高親和性ｈｉｖｔ細胞レセプター |
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| JP2008535826A true JP2008535826A (ja) | 2008-09-04 |
| JP2008535826A5 JP2008535826A5 (https=) | 2009-05-14 |
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| JP2008503585A Pending JP2008535826A (ja) | 2005-04-01 | 2006-03-29 | 高親和性ｈｉｖｔ細胞レセプター |
| JP2012049174A Expired - Fee Related JP5612623B2 (ja) | 2005-04-01 | 2012-03-06 | 高親和性ｈｉｖｔ細胞レセプター |
| JP2014094723A Expired - Fee Related JP5885220B2 (ja) | 2005-04-01 | 2014-05-01 | 高親和性ｈｉｖｔ細胞レセプター |
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| JP2012049174A Expired - Fee Related JP5612623B2 (ja) | 2005-04-01 | 2012-03-06 | 高親和性ｈｉｖｔ細胞レセプター |
| JP2014094723A Expired - Fee Related JP5885220B2 (ja) | 2005-04-01 | 2014-05-01 | 高親和性ｈｉｖｔ細胞レセプター |
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| EP (4) | EP2301964A1 (https=) |
| JP (3) | JP2008535826A (https=) |
| CN (2) | CN105461802A (https=) |
| AU (1) | AU2006228308B2 (https=) |
| CA (1) | CA2602463C (https=) |
| CY (1) | CY1118160T1 (https=) |
| DK (1) | DK2275441T3 (https=) |
| ES (2) | ES2599010T3 (https=) |
| HU (1) | HUE032037T2 (https=) |
| LT (1) | LT2275441T (https=) |
| NZ (2) | NZ561338A (https=) |
| PL (1) | PL2275441T3 (https=) |
| PT (1) | PT2275441T (https=) |
| SI (1) | SI2275441T1 (https=) |
| WO (1) | WO2006103429A2 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018527954A (ja) * | 2015-09-15 | 2018-09-27 | アダプティミューネ リミテッドＡｄａｐｔｉｍｍｕｎｅ Ｌｉｍｉｔｅｄ | Ｔｃｒライブラリ |
| JP2019512252A (ja) * | 2016-03-23 | 2019-05-16 | イムノコア リミテッド | Ｔ細胞レセプター |
| US12103971B2 (en) | 2022-02-20 | 2024-10-01 | Immunocore Limited | HIV specific binding molecules |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| AU2003216341A1 (en) | 2002-02-20 | 2003-09-09 | Dyax Corporation | Mhc-peptide complex binding ligands |
| US7994298B2 (en) | 2004-09-24 | 2011-08-09 | Trustees Of Dartmouth College | Chimeric NK receptor and methods for treating cancer |
| WO2008042814A2 (en) * | 2006-09-29 | 2008-04-10 | California Institute Of Technology | Mart-1 t cell receptors |
| JP5292550B2 (ja) * | 2007-03-23 | 2013-09-18 | 静岡県 | Ｔ細胞レセプターβ鎖遺伝子及びα鎖遺伝子 |
| US8747855B2 (en) | 2008-04-09 | 2014-06-10 | Technion Research & Development Foundation Limited | Anti human immunodeficiency antibodies and uses thereof |
| GB0816096D0 (en) * | 2008-09-04 | 2008-10-15 | Medigene Ltd | Diabetes t cell receptors |
| ES2625985T3 (es) | 2009-03-25 | 2017-07-21 | Altor Bioscience Corporation | Receptores de linfocitos T específicos de la vpr del VIH |
| CA2777053A1 (en) * | 2009-10-06 | 2011-04-14 | The Board Of Trustees Of The University Of Illinois | Human single-chain t cell receptors |
| US12492376B2 (en) | 2009-10-29 | 2025-12-09 | The Trustees Of Dartmouth College | T-cell receptor-deficient T cell compositions |
| WO2011059836A2 (en) | 2009-10-29 | 2011-05-19 | Trustees Of Dartmouth College | T cell receptor-deficient t cell compositions |
| US9273283B2 (en) | 2009-10-29 | 2016-03-01 | The Trustees Of Dartmouth College | Method of producing T cell receptor-deficient T cells expressing a chimeric receptor |
| GB201016672D0 (en) | 2010-10-04 | 2010-11-17 | Electronic Shipping Solutions Ltd | Secure exchange/authentication of electronic documents |
| EP2502934B1 (en) | 2011-03-24 | 2018-01-17 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | Single chain antigen recognizing constructs (scARCs) stabilized by the introduction of novel disulfide bonds |
| US9833476B2 (en) | 2011-08-31 | 2017-12-05 | The Trustees Of Dartmouth College | NKP30 receptor targeted therapeutics |
| ES2719495T5 (en) | 2012-05-07 | 2025-09-10 | Dartmouth College | Anti-b7-h6 antibody, fusion proteins, and methods of using the same |
| AU2013295652B2 (en) | 2012-07-27 | 2018-02-08 | The Board Of Trustees Of The University Of Illinois | Engineering T-cell receptors |
| IL290655B2 (en) | 2014-05-29 | 2024-05-01 | Us Health | Anti-human papillomavirus 16 E7 T-cell chelates |
| WO2016014725A1 (en) | 2014-07-22 | 2016-01-28 | The University Of Notre Dame Du Lac | Molecular constructs and uses thereof |
| NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
| GB201516277D0 (en) * | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR libraries |
| EP3211003A1 (en) * | 2016-02-24 | 2017-08-30 | Institut Pasteur | T cell receptors from the hiv-specific repertoire, means for their production and therapeutic uses thereof |
| PL3440105T3 (pl) | 2016-04-08 | 2022-08-29 | Immunocore Limited | Receptory komórek t |
| DE102017115966A1 (de) * | 2017-07-14 | 2019-01-17 | Immatics Biotechnologies Gmbh | Polypeptidmolekül mit verbesserter zweifacher Spezifität |
| SG11202000025SA (en) | 2017-07-14 | 2020-02-27 | Immatics Biotechnologies Gmbh | Improved dual specificity polypeptide molecule |
| WO2019217837A1 (en) * | 2018-05-11 | 2019-11-14 | Memorial Sloan-Kettering Cancer Center | T cell receptors targeting pik3ca mutations and uses thereof |
| US12606816B2 (en) * | 2018-07-31 | 2026-04-21 | Janux Therapeutics, Inc. | Inhibitory T cell receptor peptides and discovery methods |
| US12234473B2 (en) | 2020-12-31 | 2025-02-25 | Immatics US, Inc. | CD8 polypeptides, compositions, and methods of using thereof |
| KR20240149435A (ko) * | 2022-02-20 | 2024-10-14 | 이뮤노코어 리미티드 | Hiv 특이적 결합 분자 |
| CA3265218A1 (en) | 2022-08-18 | 2024-02-22 | Immunocore Ltd | MAGE A4 SPECIFIC T LYMPHOCYTE RECEPTOR FUSION PROTEINS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6759243B2 (en) * | 1998-01-20 | 2004-07-06 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
| WO1999060120A2 (en) * | 1998-05-19 | 1999-11-25 | Avidex Limited | Soluble t cell receptor |
| AU2002321581C1 (en) | 2001-08-31 | 2008-09-18 | Adaptimmune Limited | Soluble T cell receptor |
| US7751825B2 (en) | 2002-06-27 | 2010-07-06 | Qualcomm Incorporated | Controlling geographic location information of devices operating in wireless communication systems |
| AU2003271904B2 (en) | 2002-10-09 | 2009-03-05 | Adaptimmune Limited | Single chain recombinant T cell receptors |
| DE60327795D1 (de) * | 2002-11-09 | 2009-07-09 | Immunocore Ltd | T zell rezeptor "display" |
| NZ550815A (en) * | 2004-05-19 | 2009-04-30 | Immunocore Ltd | Method of improving T cell receptors |
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2006
- 2006-03-29 NZ NZ561338A patent/NZ561338A/en not_active IP Right Cessation
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- 2006-03-29 AU AU2006228308A patent/AU2006228308B2/en not_active Ceased
- 2006-03-29 EP EP06726555A patent/EP1863842A2/en not_active Withdrawn
- 2006-03-29 PT PT100086123T patent/PT2275441T/pt unknown
- 2006-03-29 HU HUE10008612A patent/HUE032037T2/en unknown
- 2006-03-29 EP EP15171918.4A patent/EP2985291B1/en not_active Expired - Lifetime
- 2006-03-29 LT LTEP10008612.3T patent/LT2275441T/lt unknown
- 2006-03-29 CN CN201510785932.6A patent/CN105461802A/zh active Pending
- 2006-03-29 ES ES10008612.3T patent/ES2599010T3/es not_active Expired - Lifetime
- 2006-03-29 NZ NZ584523A patent/NZ584523A/en not_active IP Right Cessation
- 2006-03-29 WO PCT/GB2006/001147 patent/WO2006103429A2/en not_active Ceased
- 2006-03-29 CA CA2602463A patent/CA2602463C/en not_active Expired - Fee Related
- 2006-03-29 PL PL10008612T patent/PL2275441T3/pl unknown
- 2006-03-29 SI SI200632107A patent/SI2275441T1/sl unknown
- 2006-03-29 ES ES15171918T patent/ES2699320T3/es not_active Expired - Lifetime
- 2006-03-29 DK DK10008612.3T patent/DK2275441T3/en active
- 2006-03-29 US US11/887,536 patent/US8378074B2/en not_active Expired - Fee Related
- 2006-03-29 EP EP10008612.3A patent/EP2275441B8/en not_active Expired - Lifetime
- 2006-03-29 CN CN201210563915.4A patent/CN103059128B/zh not_active Expired - Fee Related
-
2012
- 2012-03-06 JP JP2012049174A patent/JP5612623B2/ja not_active Expired - Fee Related
-
2013
- 2013-01-03 US US13/733,545 patent/US9255135B2/en not_active Expired - Fee Related
-
2014
- 2014-05-01 JP JP2014094723A patent/JP5885220B2/ja not_active Expired - Fee Related
-
2016
- 2016-10-26 CY CY20161101092T patent/CY1118160T1/el unknown
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018527954A (ja) * | 2015-09-15 | 2018-09-27 | アダプティミューネ リミテッドＡｄａｐｔｉｍｍｕｎｅ Ｌｉｍｉｔｅｄ | Ｔｃｒライブラリ |
| JP2019512252A (ja) * | 2016-03-23 | 2019-05-16 | イムノコア リミテッド | Ｔ細胞レセプター |
| JP7051699B2 (ja) | 2016-03-23 | 2022-04-11 | イムノコア リミテッド | Ｔ細胞レセプター |
| US11440944B2 (en) | 2016-03-23 | 2022-09-13 | Immunocore Limited | Engineered immune-mobilizing T-cell receptors with enhanced affinity for HIV-1 Gag |
| US12103971B2 (en) | 2022-02-20 | 2024-10-01 | Immunocore Limited | HIV specific binding molecules |
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