JP2008533050A - 緑内障を処置するためのフリッツルド関連蛋白質―１のｒｎａｉ媒介性阻害 - Google Patents
緑内障を処置するためのフリッツルド関連蛋白質―１のｒｎａｉ媒介性阻害 Download PDFInfo
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| US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| RU2010117178A (ru) * | 2007-10-01 | 2011-11-10 | Алькон Рисерч, Лтд. (Us) | Опосредованная самокомплементарными aav доставка молекул, интерферирующих рнк для лечения или профилактики глазных заболеваний |
| US7973019B1 (en) | 2007-10-03 | 2011-07-05 | Alcon Research, Ltd. | Transferrin/transferrin receptor-mediated siRNA delivery |
| AR069328A1 (es) | 2007-11-15 | 2010-01-13 | Alcon Mfg Ltd | Liberacion de rna interferente corto o sirna, intermediada por receptor de lipoproteina de baja densidad |
| TW200932274A (en) | 2007-12-18 | 2009-08-01 | Alcon Res Ltd | Interfering RNA delivery system and uses thereof |
| US20120271272A1 (en) | 2010-10-15 | 2012-10-25 | Iscience Interventional Corporation | Device for ocular access |
| WO2012161677A1 (en) | 2011-05-20 | 2012-11-29 | Alcon Research, Ltd. | TRANSFERRIN/TRANSFERRIN RECEPTOR-MEDIATED siRNA DELIVERY |
| US20130178421A1 (en) | 2012-01-06 | 2013-07-11 | Alcon Research, Ltd. | Interfering rna delivery system and uses thereof |
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| SG11201501385UA (en) | 2012-09-05 | 2015-03-30 | Sylentis Sau | Sirna and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| EP2916827B1 (en) | 2012-11-08 | 2020-06-10 | Clearside Biomedical Inc. | Methods for the treatment of ocular disease in human subjects |
| SG10201702674PA (en) | 2013-05-03 | 2017-06-29 | Clearside Biomedical Inc | Apparatus and methods for ocular injection |
| EP3003454B1 (en) | 2013-06-03 | 2020-01-08 | Clearside Biomedical, Inc. | Apparatus for drug delivery using multiple reservoirs |
| US10011837B2 (en) | 2014-03-04 | 2018-07-03 | Sylentis Sau | SiRNAs and their use in methods and compositions for the treatment and/or prevention of eye conditions |
| RU2710491C2 (ru) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань |
| USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
| WO2017139375A1 (en) | 2016-02-10 | 2017-08-17 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
| CA3062845A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
| EP3496680B1 (en) | 2016-08-12 | 2024-10-02 | Clearside Biomedical, Inc. | Device for adjusting the insertion depth of a needle for medicament delivery |
| WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
| JP7641902B2 (ja) * | 2019-01-29 | 2025-03-07 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ カリフォルニア | 緑内障の新規治療法 |
| US20230201371A1 (en) * | 2020-03-19 | 2023-06-29 | Clearside Biomedical, Inc. | Compositions and methods for treating ocular disorders |
| EP4536197A1 (en) | 2022-06-07 | 2025-04-16 | Generation Bio Co. | Lipid nanoparticle compositions and uses thereof |
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| EP2314700A1 (en) * | 1999-01-28 | 2011-04-27 | Medical College of Georgia Research Institute, Inc | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA |
| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| US20080166356A9 (en) * | 1999-09-13 | 2008-07-10 | Peter Bodine | Pharmaceutical compositions and methods of using secreted frizzled related protein |
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| EP1974738A3 (en) * | 2000-02-29 | 2008-12-17 | Alcon, Inc. | Diagnostics and therapeutics for glaucoma |
| DE10012340A1 (de) | 2000-03-14 | 2001-09-20 | Merck Patent Gmbh | Verfahren zur Baeyer-Villiger-Oxidation organischer Carbonylverbindungen |
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2006
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- 2006-03-10 EP EP06738105A patent/EP1856259A1/en not_active Ceased
- 2006-03-10 MX MX2007010608A patent/MX2007010608A/es active IP Right Grant
- 2006-03-10 AU AU2006223131A patent/AU2006223131A1/en not_active Abandoned
- 2006-03-10 CA CA002598234A patent/CA2598234A1/en not_active Abandoned
- 2006-03-10 US US11/373,376 patent/US7947660B2/en active Active
- 2006-03-10 JP JP2008501049A patent/JP2008533050A/ja not_active Withdrawn
- 2006-03-10 BR BRPI0609206-3A patent/BRPI0609206A2/pt not_active Application Discontinuation
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2011
- 2011-04-12 US US13/084,944 patent/US8173617B2/en not_active Expired - Lifetime
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2012
- 2012-03-26 US US13/429,913 patent/US9040494B2/en active Active
- 2012-07-10 JP JP2012154550A patent/JP2012193197A/ja active Pending
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| WO2005019453A2 (en) * | 2001-05-18 | 2005-03-03 | Sirna Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) |
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| JP2012193197A (ja) * | 2005-03-11 | 2012-10-11 | Alcon Inc | 緑内障を処置するためのフリッツルド関連蛋白質―１のｒｎａｉ媒介性阻害 |
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| US20170073681A1 (en) | 2017-03-16 |
| WO2006099353A1 (en) | 2006-09-21 |
| US8173617B2 (en) | 2012-05-08 |
| US20150307882A1 (en) | 2015-10-29 |
| US20110190381A1 (en) | 2011-08-04 |
| US20060223773A1 (en) | 2006-10-05 |
| BRPI0609206A2 (pt) | 2010-03-02 |
| KR20080018858A (ko) | 2008-02-28 |
| US7947660B2 (en) | 2011-05-24 |
| US9040494B2 (en) | 2015-05-26 |
| US20120178795A1 (en) | 2012-07-12 |
| CA2598234A1 (en) | 2006-09-21 |
| US9550994B2 (en) | 2017-01-24 |
| JP2012193197A (ja) | 2012-10-11 |
| AU2006223131A1 (en) | 2006-09-21 |
| MX2007010608A (es) | 2007-10-19 |
| EP1856259A1 (en) | 2007-11-21 |
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