JP2008532605A - 皮膚用包帯に関する改良 - Google Patents

皮膚用包帯に関する改良 Download PDF

Info

Publication number
JP2008532605A
JP2008532605A JP2008500274A JP2008500274A JP2008532605A JP 2008532605 A JP2008532605 A JP 2008532605A JP 2008500274 A JP2008500274 A JP 2008500274A JP 2008500274 A JP2008500274 A JP 2008500274A JP 2008532605 A JP2008532605 A JP 2008532605A
Authority
JP
Japan
Prior art keywords
bandage
nitrite
nitrosothiol
dry
thiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008500274A
Other languages
English (en)
Japanese (ja)
Inventor
ジェゼク、ジャン
ワトソン、リン・パトリシア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Insense Ltd
Original Assignee
Insense Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insense Ltd filed Critical Insense Ltd
Publication of JP2008532605A publication Critical patent/JP2008532605A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114—Nitric oxide, i.e. NO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A61L2300/254—Enzymes, proenzymes
JP2008500274A 2005-03-11 2006-03-10 皮膚用包帯に関する改良 Pending JP2008532605A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0505035.6A GB0505035D0 (en) 2005-03-11 2005-03-11 Improvements relating to skin dressings
PCT/GB2006/000873 WO2006095193A2 (en) 2005-03-11 2006-03-10 Improvements relating to skin dressings

Publications (1)

Publication Number Publication Date
JP2008532605A true JP2008532605A (ja) 2008-08-21

Family

ID=34508905

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008500274A Pending JP2008532605A (ja) 2005-03-11 2006-03-10 皮膚用包帯に関する改良

Country Status (13)

Country Link
US (1) US20090081279A1 (US20090081279A1-20090326-C00002.png)
EP (1) EP1855731B1 (US20090081279A1-20090326-C00002.png)
JP (1) JP2008532605A (US20090081279A1-20090326-C00002.png)
KR (1) KR20070112158A (US20090081279A1-20090326-C00002.png)
CN (1) CN101137403A (US20090081279A1-20090326-C00002.png)
AT (1) ATE438417T1 (US20090081279A1-20090326-C00002.png)
AU (1) AU2006221794B2 (US20090081279A1-20090326-C00002.png)
CA (1) CA2599287C (US20090081279A1-20090326-C00002.png)
DE (1) DE602006008280D1 (US20090081279A1-20090326-C00002.png)
DK (1) DK1855731T3 (US20090081279A1-20090326-C00002.png)
ES (1) ES2329934T3 (US20090081279A1-20090326-C00002.png)
GB (1) GB0505035D0 (US20090081279A1-20090326-C00002.png)
WO (1) WO2006095193A2 (US20090081279A1-20090326-C00002.png)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2833997C (en) * 2001-09-05 2017-09-26 Geno Llc Method and apparatus for nitric oxide generation
ATE329628T1 (de) 2002-04-24 2006-07-15 Insense Ltd Wundauflage enthaltend ein oxidoreduktase-enzym in hydratiertem zustand
GB0313217D0 (en) 2003-06-09 2003-07-16 Insense Ltd Improvements in or relating to skin dressings
US20050181026A1 (en) * 2003-06-09 2005-08-18 Insense Limited Skin dressings
US20070148117A1 (en) * 2004-01-30 2007-06-28 Davis Paul J Skin dressings
EP3556401A1 (en) 2005-05-27 2019-10-23 The University of North Carolina at Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
AU2006287460A1 (en) 2005-09-07 2007-03-15 Tyco Healthcare Group Lp Wound dressing with vacuum reservoir
GB0614278D0 (en) * 2006-07-19 2006-08-30 Insense Ltd Hydrogen peroxide delivery system
US20090311292A1 (en) * 2006-09-14 2009-12-17 Cristalia Produtos Quimicos Farmaceuticos Ltda. Process for synthesis and incorporation of nitric oxide donors in macromolecular compositions
US7975699B2 (en) * 2007-10-30 2011-07-12 The Invention Science Fund I, Llc Condoms configured to facilitate release of nitric oxide
US20110190604A1 (en) * 2006-12-22 2011-08-04 Hyde Roderick A Nitric oxide sensors and systems
US7862598B2 (en) 2007-10-30 2011-01-04 The Invention Science Fund I, Llc Devices and systems that deliver nitric oxide
US20090110933A1 (en) * 2007-10-30 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems and devices related to nitric oxide releasing materials
US8221690B2 (en) 2007-10-30 2012-07-17 The Invention Science Fund I, Llc Systems and devices that utilize photolyzable nitric oxide donors
US8642093B2 (en) 2007-10-30 2014-02-04 The Invention Science Fund I, Llc Methods and systems for use of photolyzable nitric oxide donors
US9278157B2 (en) 2007-08-09 2016-03-08 Insense Limited Nitric oxide-generating skin dressings
GB0715554D0 (en) * 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
US9345804B2 (en) 2007-08-09 2016-05-24 Insense Limited S-nitrosothiol-generating skin dressings
CA2599082A1 (en) * 2007-08-27 2009-02-27 Ping I. Lee Supramacromolecular polymer complexes providing controlled nitric oxide release for healing wounds
US20090112055A1 (en) * 2007-10-30 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Sleeves configured to facilitate release of nitric oxide
US8980332B2 (en) 2007-10-30 2015-03-17 The Invention Science Fund I, Llc Methods and systems for use of photolyzable nitric oxide donors
US7846400B2 (en) 2007-10-30 2010-12-07 The Invention Science Fund I, Llc Substrates for nitric oxide releasing devices
US8877508B2 (en) * 2007-10-30 2014-11-04 The Invention Science Fund I, Llc Devices and systems that deliver nitric oxide
US7897399B2 (en) 2007-10-30 2011-03-01 The Invention Science Fund I, Llc Nitric oxide sensors and systems
US20090112193A1 (en) * 2007-10-30 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems and devices that utilize photolyzable nitric oxide donors
US10080823B2 (en) 2007-10-30 2018-09-25 Gearbox Llc Substrates for nitric oxide releasing devices
US20090177133A1 (en) * 2008-01-04 2009-07-09 Kristine Kieswetter Reduced pressure dressing coated with biomolecules
WO2010048724A1 (en) * 2008-10-30 2010-05-06 Chris Miller Nitric oxide-releasing dressings
US20100179646A1 (en) * 2009-01-09 2010-07-15 Rainbow Medical Ltd. Glucose oxidase techniques
GB0901456D0 (en) * 2009-01-29 2009-03-11 Insense Ltd Treatment of psoriasis
BR112012003804B1 (pt) 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
WO2011022652A1 (en) 2009-08-21 2011-02-24 Novan, Inc. Topical gels
US9999702B2 (en) 2010-04-09 2018-06-19 Kci Licensing Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
US9034355B2 (en) * 2011-02-24 2015-05-19 Colorado State University Research Foundation Materials for modulating biological responses and methods of making
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
US8597264B2 (en) 2011-03-24 2013-12-03 Kci Licensing, Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
WO2013130687A1 (en) 2012-03-01 2013-09-06 3M Innovative Properties Company Method of promoting wound healing
CN104284695A (zh) 2012-03-23 2015-01-14 微阵列有限公司 带有电极和有生理学活性的前体物质的皮肤敷料
EP2976095B1 (en) 2013-03-15 2020-12-23 3M Innovative Properties Company Wound healing compositions
GB201506236D0 (en) * 2015-04-13 2015-05-27 Jellagen Pty Ltd Modified collagen, methods of manufacture thereof
CA3014762A1 (en) * 2016-02-16 2017-08-24 Avent, Inc. System and method for preserving and delivering a therapeutic gas to a wound
EP3246050A1 (de) * 2016-05-17 2017-11-22 BSN medical GmbH Wund- oder hautauflage
GB201614961D0 (en) 2016-09-02 2016-10-19 Relaxsol Ltd Compounds and compositions for use
KR101960585B1 (ko) * 2017-01-19 2019-03-21 전자부품연구원 하이드로젤을 포함하는 부착형 화학 센서 및 그 제조방법
US11883807B2 (en) 2017-04-11 2024-01-30 Colorado State University Research Foundation Functionalization of metal-organic frameworks
US20190365797A1 (en) * 2018-06-05 2019-12-05 Zylo Therapeutics, Inc. Systems and Methods for Delivery of Nitric Oxide
CN110639052B (zh) * 2019-09-30 2021-06-29 新乡医学院 一种促进创面愈合的复合凝胶体系及其制备方法和应用
WO2021069875A1 (en) * 2019-10-07 2021-04-15 Insense Limited Composition for delivering nitric oxide to skin
GB2589549A (en) * 2019-10-07 2021-06-09 Insense Ltd Composition for delivering nitric oxide to skin
CN112618158A (zh) * 2019-10-09 2021-04-09 咏达生医材料股份有限公司 一种供给一氧化氮的多层装置
CN110680952B (zh) * 2019-10-29 2021-12-14 无锡贝迪生物工程股份有限公司 一种可注射型具有抑菌功能的医用创面敷料
US20210228765A1 (en) * 2020-01-28 2021-07-29 Becton, Dickinson And Company Self-activating catheter insertion site dressing
GB2608775A (en) * 2020-04-02 2023-01-11 Smith & Nephew Wound dressing control and activation
CN111481737A (zh) * 2020-05-07 2020-08-04 华东理工大学 近红外光控释放一氧化氮的磁性温敏性水凝胶及其制备和应用
CN113101053A (zh) * 2021-03-30 2021-07-13 上海健康医学院 一种可释放一氧化氮的创伤敷料

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003090800A1 (en) * 2002-04-24 2003-11-06 Insense Limited Wound dressings comprising hydrated hydrogels and enzymes
JP2005505321A (ja) * 2001-08-23 2005-02-24 ボストン サイエンティフィック リミテッド 再狭窄の局所的治療のための構成体及び技術

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1543323A1 (de) * 1965-11-02 1969-08-07 Ajinomoto Kk Verfahren zur Herstellung von L-Serin
NO753778L (US20090081279A1-20090326-C00002.png) * 1974-11-14 1976-05-18 Smith & Nephew Pharma
US4010259A (en) * 1975-07-17 1977-03-01 Johansson J A Olof Disinfectants containing iodine complexed to a hydrophilic organic carrier
US4278548A (en) * 1979-08-20 1981-07-14 E. I. Du Pont De Nemours And Company Control of biological growth in reverse osmosis permeators
US4391799A (en) * 1980-02-15 1983-07-05 The United States Of America As Represented By The Secretary Of The Army Protective gel composition for treating white phosphorus burn wounds
US4327731A (en) * 1980-07-07 1982-05-04 Powell Nelson B Moisture indicator
GB2083827B (en) * 1980-09-11 1984-03-28 Atomic Energy Authority Uk Biologically active composites
US4476108A (en) * 1981-01-16 1984-10-09 Kessler Jack H Bactericidal method
US4581336A (en) * 1982-04-26 1986-04-08 Uop Inc. Surface-modified electrodes
IT1163947B (it) * 1982-10-06 1987-04-08 Novo Industri As Metodo per la produzione di un preparato di enzima immobilizzato per mezzo di un agente di reticolazione
US4783448A (en) * 1983-06-07 1988-11-08 Perstorp Ab Method for cleansing an infected sore
US4576817A (en) * 1984-06-07 1986-03-18 Laclede Professional Products, Inc. Enzymatic bandages and pads
GB8422950D0 (en) * 1984-09-11 1984-10-17 Warne K J Hydrogel
US4657864A (en) * 1985-06-18 1987-04-14 Westvaco Corporation Method for stabilizing peroxidase solutions
US4775626A (en) * 1986-05-23 1988-10-04 Syntex (U.S.A.) Inc. Method and compositions for protecting anerobic microorganisms
DE3620685A1 (de) * 1986-06-20 1987-12-23 Henkel Kgaa Neue mittel zur abdeckung unverletzter und/oder verletzter bereiche menschlicher oder tierischer haut
US5232914A (en) * 1988-04-11 1993-08-03 Epitope, Inc. Solid, storage-stable, germicidal, pre-iodine composition
US4900719A (en) * 1988-08-05 1990-02-13 The Ohio State University Nitrosothiols as hypotensive agents
US5483697A (en) * 1989-05-22 1996-01-16 Board Of Regents The University Of Texas Multilayer protective coverings with a sealing solution
GB9002422D0 (en) * 1990-02-03 1990-04-04 Boots Co Plc Anti-microbial compositions
JP3046346B2 (ja) * 1990-03-12 2000-05-29 昭和電工株式会社 外用剤基剤又は補助剤とそれを含有する人又は動物の外用剤
US5196190A (en) * 1990-10-03 1993-03-23 Zenith Technology Corporation, Limited Synthetic skin substitutes
US5762638A (en) * 1991-02-27 1998-06-09 Shikani; Alain H. Anti-infective and anti-inflammatory releasing systems for medical devices
US5652274A (en) * 1991-03-01 1997-07-29 Martin; Alain Therapeutic-wound healing compositions and methods for preparing and using same
US5804213A (en) * 1991-10-09 1998-09-08 Lectec Corporation Biologically active aqueous gel wound dressing
US5552316A (en) * 1993-06-04 1996-09-03 Environmental Marketing Services, Ltd. Clarifying E. coli fermentation broths with a combination of anionic and cationic flocculants
US5372802A (en) * 1993-09-02 1994-12-13 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Stabilized peroxide gels containing fluoride
US5648075A (en) * 1994-10-17 1997-07-15 Symbollon Corporation Iodine based germicidal composition
US5792090A (en) * 1995-06-15 1998-08-11 Ladin; Daniel Oxygen generating wound dressing
US5696456A (en) * 1996-02-29 1997-12-09 Micron Technology, Inc. Enhanced low voltage TTL interface
GB9622997D0 (en) * 1996-11-05 1997-01-08 Univ St Andrews Nitric oxide donor drugs
US5849241A (en) * 1996-12-20 1998-12-15 Colgate-Palmolive Company Multichamber container with expanded interior walls
US6103275A (en) * 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
EP1100557B1 (en) * 1998-07-31 2006-12-06 First Water Limited Bioadhesive compositions comprising hydrophobic polymers
US6858403B2 (en) * 1999-05-11 2005-02-22 M-Biotech, Inc. Polymer matrix containing catalase co-immobilized with analytic enzyme that generates hydrogen peroxide
ATE327779T1 (de) * 1999-12-30 2006-06-15 Acrymed Methode und zusammensetzungen für verbesserte abgabevorrichtungen
US20030082225A1 (en) * 2001-10-19 2003-05-01 Mason Paul Arthur Sterile, breathable patch for treating wound pain
US7217853B2 (en) * 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
GB0313217D0 (en) * 2003-06-09 2003-07-16 Insense Ltd Improvements in or relating to skin dressings
US20050181026A1 (en) * 2003-06-09 2005-08-18 Insense Limited Skin dressings
JP2006526995A (ja) * 2003-06-09 2006-11-30 インセンス・リミテッド 殺菌放射線への曝露時に酵素を安定化させる方法
GB0427444D0 (en) * 2004-01-30 2005-01-19 Insense Ltd Improvements relating to skin dressings
US20070148117A1 (en) * 2004-01-30 2007-06-28 Davis Paul J Skin dressings
GB0614278D0 (en) * 2006-07-19 2006-08-30 Insense Ltd Hydrogen peroxide delivery system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005505321A (ja) * 2001-08-23 2005-02-24 ボストン サイエンティフィック リミテッド 再狭窄の局所的治療のための構成体及び技術
WO2003090800A1 (en) * 2002-04-24 2003-11-06 Insense Limited Wound dressings comprising hydrated hydrogels and enzymes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012014258; Ｂｒｉｔｉｓｈ　Ｊｏｕｒｎａｌ　ｏｆ　Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１５１，Ｎｏ．５, 2004, ｐ９７７-９８３ *
JPN6012014260; ＦＡＳＥＢ　Ｊｏｕｒｎａｌ Ｖｏｌ．１３，Ｎｏ．１４, 1999, ｐ２００２-２０１４ *
JPN6012014261; Ｗｏｕｎｄ　Ｒｅｐａｉｒ　ａｎｄ　Ｒｅｇｅｎｅｒａｔｉｏｎ Ｖｏｌ．１０，Ｎｏ．５, 2002, ｐ２８６-２９４ *

Also Published As

Publication number Publication date
ATE438417T1 (de) 2009-08-15
DE602006008280D1 (de) 2009-09-17
EP1855731B1 (en) 2009-08-05
WO2006095193A2 (en) 2006-09-14
EP1855731A2 (en) 2007-11-21
KR20070112158A (ko) 2007-11-22
GB0505035D0 (en) 2005-04-20
AU2006221794B2 (en) 2011-06-16
AU2006221794A1 (en) 2006-09-14
ES2329934T3 (es) 2009-12-02
WO2006095193A3 (en) 2006-12-21
CA2599287C (en) 2013-04-23
US20090081279A1 (en) 2009-03-26
CN101137403A (zh) 2008-03-05
DK1855731T3 (da) 2009-11-09
CA2599287A1 (en) 2006-09-14

Similar Documents

Publication Publication Date Title
JP2008532605A (ja) 皮膚用包帯に関する改良
EP2173391B1 (en) Improvements relating to skin dressings
JP5489171B2 (ja) 皮膚包帯材に関する改良
EP1496951B1 (en) Wound dressings comprising an oxidoreductase enzyme in hydrated condition
US9345804B2 (en) S-nitrosothiol-generating skin dressings
US20110287113A1 (en) Treatment of psoriasis
JP2022550990A (ja) 皮膚に一酸化窒素を送達する組成物

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090304

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120321

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120619

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130115