JP2008531739A - 治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用 - Google Patents

治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用 Download PDF

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JP2008531739A
JP2008531739A JP2008500016A JP2008500016A JP2008531739A JP 2008531739 A JP2008531739 A JP 2008531739A JP 2008500016 A JP2008500016 A JP 2008500016A JP 2008500016 A JP2008500016 A JP 2008500016A JP 2008531739 A JP2008531739 A JP 2008531739A
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cancer
cells
virus
myxoma virus
rapamycin
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JP2008531739A5 (enExample
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グラント マクファドゥン,
ジョン バレット,
マリアンヌ スタンフォード,
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ロバーツ リサーチ インスティテュート
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/768Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

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  • Health & Medical Sciences (AREA)
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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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JP2008500016A 2005-03-07 2006-03-06 治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用 Pending JP2008531739A (ja)

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Application Number Priority Date Filing Date Title
US65881605P 2005-03-07 2005-03-07
PCT/CA2006/000315 WO2006094385A1 (en) 2005-03-07 2006-03-06 Use of a combination of myxoma virus and rapamycin for therapeutic treatment

Related Child Applications (1)

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JP2012197457A Division JP5674210B2 (ja) 2005-03-07 2012-09-07 治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用

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JP2008531739A true JP2008531739A (ja) 2008-08-14
JP2008531739A5 JP2008531739A5 (enExample) 2009-04-16

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JP2008500016A Pending JP2008531739A (ja) 2005-03-07 2006-03-06 治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用
JP2012197457A Expired - Fee Related JP5674210B2 (ja) 2005-03-07 2012-09-07 治療的処置のための粘液腫ウイルスとラパマイシンの組み合わせの使用

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US (5) US20090035276A1 (enExample)
EP (2) EP1863906A4 (enExample)
JP (2) JP2008531739A (enExample)
KR (1) KR101479093B1 (enExample)
CN (2) CN101137748B (enExample)
AU (1) AU2006222500B2 (enExample)
CA (1) CA2600675C (enExample)
DK (1) DK2388315T3 (enExample)
IL (2) IL185376A0 (enExample)
MX (1) MX2007010962A (enExample)
NZ (2) NZ560840A (enExample)
RU (1) RU2461630C2 (enExample)
UA (1) UA96412C2 (enExample)
WO (1) WO2006094385A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022524173A (ja) * 2018-09-05 2022-04-28 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー 血液癌を処置するための腫瘍溶解性ウイルスプラットフォーム
JP2022546985A (ja) * 2019-09-02 2022-11-10 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー 非許容性の癌に対する腫瘍溶解性ウイルスの感染を改善する方法および組成物

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ560840A (en) 2005-03-07 2009-07-31 Robarts Res Inst Use of a combination of myxoma virus and rapamycin for therapeutic treatment
KR20090014364A (ko) 2006-06-01 2009-02-10 로바츠 리서치 인스티튜트 암 치료용 점액종 바이러스 변이종
CN102124335B (zh) * 2008-05-22 2014-07-30 第一药品株式会社 基于肿瘤抑制因子的过度增生细胞对溶瘤病毒疗法的敏感性
US20120100109A1 (en) * 2010-10-26 2012-04-26 Xiaoliu Zhang Method for increasing the replication of oncolytic HSVs in highly resistant tumor cells using mTOR pathway and PI3K inhibitors
DK2717887T3 (en) 2011-06-09 2018-04-09 Univ Florida Methods for treating or preventing graft-versus-host disease
RU2695136C1 (ru) * 2018-06-19 2019-07-22 Общество с ограниченной ответственностью Биотехнология (ООО Биотехнология) Онколитический способ терапии рака молочной железы.
SG11202101291VA (en) * 2018-08-08 2021-03-30 Univ Arizona State Method for improved poxvirus yields
KR20220078665A (ko) * 2019-10-10 2022-06-10 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 다중특이적 면역 세포 인게이저를 발현하는 종양용해 바이러스
AU2020361625A1 (en) * 2019-10-10 2022-05-05 Arizona Board Of Regents On Behalf Of Arizona State University Oncolytic virus comprising immunomodulatory transgenes and uses thereof
WO2022139440A1 (ko) * 2020-12-22 2022-06-30 바이로큐어 주식회사 신규한 재조합 믹소마바이러스 및 이의 용도

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JPS57159716A (en) * 1981-03-09 1982-10-01 Ayerst Mckenna & Harrison Antitumoral agent
JP2003514024A (ja) * 1999-11-12 2003-04-15 オンコリティクス バイオテク,インコーポレーテッド 細胞増殖性疾患の治療のためのウイルス
JP2004525899A (ja) * 2001-02-19 2004-08-26 ノバルティス アクチエンゲゼルシャフト 癌の処置
WO2004078206A1 (en) * 2003-03-07 2004-09-16 Robarts Research Institute Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection
WO2004093854A2 (en) * 2003-04-22 2004-11-04 Wyeth Antineoplastic combinations
WO2005002607A2 (en) * 2003-07-07 2005-01-13 Oncolytics Biotech Inc. Oncolytic reoviruses for the treatment of neoplasms having activated pp2a or rac
JP2005505549A (ja) * 2001-08-07 2005-02-24 ワイス 抗腫瘍薬組み合わせ

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JP2003514024A (ja) * 1999-11-12 2003-04-15 オンコリティクス バイオテク,インコーポレーテッド 細胞増殖性疾患の治療のためのウイルス
JP2004525899A (ja) * 2001-02-19 2004-08-26 ノバルティス アクチエンゲゼルシャフト 癌の処置
JP2005505549A (ja) * 2001-08-07 2005-02-24 ワイス 抗腫瘍薬組み合わせ
WO2004078206A1 (en) * 2003-03-07 2004-09-16 Robarts Research Institute Use of myxoma virus for the therapeutic treatment of cancer and chronic viral infection
WO2004093854A2 (en) * 2003-04-22 2004-11-04 Wyeth Antineoplastic combinations
WO2005002607A2 (en) * 2003-07-07 2005-01-13 Oncolytics Biotech Inc. Oncolytic reoviruses for the treatment of neoplasms having activated pp2a or rac

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022524173A (ja) * 2018-09-05 2022-04-28 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー 血液癌を処置するための腫瘍溶解性ウイルスプラットフォーム
JP2022546985A (ja) * 2019-09-02 2022-11-10 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー 非許容性の癌に対する腫瘍溶解性ウイルスの感染を改善する方法および組成物

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EP2388315A3 (en) 2012-05-02
EP1863906A1 (en) 2007-12-12
RU2461630C2 (ru) 2012-09-20
EP1863906A4 (en) 2009-06-03
EP2388315B1 (en) 2014-05-21
US20140134134A1 (en) 2014-05-15
AU2006222500B2 (en) 2011-09-01
JP2012236860A (ja) 2012-12-06
RU2007137008A (ru) 2009-04-20
CA2600675C (en) 2015-12-15
WO2006094385A1 (en) 2006-09-14
CN102357104A (zh) 2012-02-22
EP2388315A2 (en) 2011-11-23
IL208070A0 (en) 2010-12-30
IL185376A0 (en) 2008-02-09
JP5674210B2 (ja) 2015-02-25
HK1163175A1 (en) 2012-09-07
CN101137748B (zh) 2011-12-14
KR101479093B1 (ko) 2015-01-26
KR20070110423A (ko) 2007-11-16
IL208070A (en) 2015-06-30
CA2600675A1 (en) 2006-09-14
US20130171106A1 (en) 2013-07-04
US20090035276A1 (en) 2009-02-05
CN101137748A (zh) 2008-03-05
NZ577283A (en) 2010-11-26
DK2388315T3 (da) 2014-08-25
CN102357104B (zh) 2016-01-27
AU2006222500A1 (en) 2006-09-14
US9987315B2 (en) 2018-06-05
UA96412C2 (ru) 2011-11-10
US20180256656A1 (en) 2018-09-13
US20110195050A1 (en) 2011-08-11
MX2007010962A (es) 2008-03-10
NZ560840A (en) 2009-07-31

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