JP2008530988A5 - - Google Patents
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- Publication number
- JP2008530988A5 JP2008530988A5 JP2007554515A JP2007554515A JP2008530988A5 JP 2008530988 A5 JP2008530988 A5 JP 2008530988A5 JP 2007554515 A JP2007554515 A JP 2007554515A JP 2007554515 A JP2007554515 A JP 2007554515A JP 2008530988 A5 JP2008530988 A5 JP 2008530988A5
- Authority
- JP
- Japan
- Prior art keywords
- modifications
- modifications include
- amino
- label
- dichlorocarbodiimide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- WGJUFIXHTBAMBX-BYPYZUCNSA-N (2s)-2,6,6-triaminohexanoic acid Chemical group NC(N)CCC[C@H](N)C(O)=O WGJUFIXHTBAMBX-BYPYZUCNSA-N 0.000 description 1
- 238000006664 bond formation reaction Methods 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000022811 deglycosylation Effects 0.000 description 1
- 239000000539 dimer Substances 0.000 description 1
- 238000006471 dimerization reaction Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- LYIXRFRBQFWQBI-UHFFFAOYSA-N n,n'-dichloromethanediimine Chemical compound ClN=C=NCl LYIXRFRBQFWQBI-UHFFFAOYSA-N 0.000 description 1
- 238000006384 oligomerization reaction Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000004481 post-translational protein modification Effects 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000011191 terminal modification Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05003095A EP1690875A1 (en) | 2005-02-14 | 2005-02-14 | Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype |
| EP05003095.6 | 2005-02-14 | ||
| PCT/EP2006/001289 WO2006084758A1 (en) | 2005-02-14 | 2006-02-13 | Human monoclonal antibody specific for lipopolysaccharides (lps) of the pseudomonas aeruginosa iats o11 serotype |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530988A JP2008530988A (ja) | 2008-08-14 |
| JP2008530988A5 true JP2008530988A5 (https=) | 2011-10-13 |
| JP4944799B2 JP4944799B2 (ja) | 2012-06-06 |
Family
ID=34933741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007554515A Expired - Fee Related JP4944799B2 (ja) | 2005-02-14 | 2006-02-13 | 緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）ＩＡＴＳＯ１１血清型のリポ多糖類（ＬＰＳ）に対して特異的なヒトモノクローナル抗体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8197816B2 (https=) |
| EP (2) | EP1690875A1 (https=) |
| JP (1) | JP4944799B2 (https=) |
| KR (2) | KR20070107756A (https=) |
| CN (1) | CN101120018B (https=) |
| AT (1) | ATE480563T1 (https=) |
| CA (1) | CA2597701C (https=) |
| DE (1) | DE602006016736D1 (https=) |
| ES (1) | ES2348263T3 (https=) |
| IL (1) | IL184774A (https=) |
| WO (1) | WO2006084758A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2571673A1 (en) * | 2004-06-28 | 2006-01-05 | Proteome Systems Intellectual Property Pty Ltd | Novel methods of diagnosis of treatment of p. aeruginosa infection and reagents therefor |
| EP2417157A1 (en) * | 2009-04-09 | 2012-02-15 | Kenta Biotech AG | Human monoclonal antibody specific for lipolysaccarides (lps) of serotype lats 01 of pseudomonas aeruginosa |
| KR20120128686A (ko) * | 2010-02-18 | 2012-11-27 | 심포젠 에이/에스 | 녹농균의 혈청형 ａ 지질다당류에 대한 항체 |
| EP2361989A1 (en) * | 2010-02-26 | 2011-08-31 | Kenta Biotech AG | Assays and kits for serotyping Pseudomonas aeruginosa and oligonucleotide sequences useful in such methods and kits |
| CA2925897A1 (en) * | 2013-09-30 | 2015-04-02 | Daiichi Sankyo Company, Limited | Anti-lps o11 antibody |
| WO2017083515A2 (en) | 2015-11-10 | 2017-05-18 | Visterra, Inc. | Antibody molecule-drug conjugates and uses thereof |
| JP7303110B2 (ja) | 2017-01-18 | 2023-07-04 | ビステラ， インコーポレイテッド | 抗体分子－薬物コンジュゲートおよびその使用 |
| KR20240085798A (ko) | 2020-04-03 | 2024-06-17 | 비스테라, 인크. | 항체 분자-약물 접합체 및 이의 용도 |
| EP4512826A3 (en) | 2021-07-09 | 2025-04-02 | Luxembourg Institute Of Health (LIH) | Dimeric protein complexes and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ218499A (en) * | 1985-12-10 | 1990-04-26 | Genetic Systems Corp | Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods |
| JP4398620B2 (ja) | 2000-02-03 | 2010-01-13 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | ヒト化抗ｃｃｒ−２抗体およびその使用方法 |
| EP1319025A2 (en) * | 2000-09-07 | 2003-06-18 | John R. Schreiber | Human antibodies against pseudomonas aeruginosa lps derived from transgenic xenomouse |
-
2005
- 2005-02-14 EP EP05003095A patent/EP1690875A1/en not_active Withdrawn
-
2006
- 2006-02-13 WO PCT/EP2006/001289 patent/WO2006084758A1/en not_active Ceased
- 2006-02-13 KR KR1020077020669A patent/KR20070107756A/ko not_active Ceased
- 2006-02-13 AT AT06706900T patent/ATE480563T1/de active
- 2006-02-13 US US11/884,163 patent/US8197816B2/en not_active Expired - Fee Related
- 2006-02-13 EP EP06706900A patent/EP1848741B1/en not_active Expired - Lifetime
- 2006-02-13 CN CN2006800048470A patent/CN101120018B/zh not_active Expired - Fee Related
- 2006-02-13 KR KR1020137000972A patent/KR20130018991A/ko not_active Ceased
- 2006-02-13 DE DE602006016736T patent/DE602006016736D1/de not_active Expired - Lifetime
- 2006-02-13 CA CA2597701A patent/CA2597701C/en not_active Expired - Fee Related
- 2006-02-13 JP JP2007554515A patent/JP4944799B2/ja not_active Expired - Fee Related
- 2006-02-13 ES ES06706900T patent/ES2348263T3/es not_active Expired - Lifetime
-
2007
- 2007-07-23 IL IL184774A patent/IL184774A/en active IP Right Grant
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