JP2008530225A - インダゾール−カルボキサミド化合物の結晶型 - Google Patents
インダゾール−カルボキサミド化合物の結晶型 Download PDFInfo
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- JP2008530225A JP2008530225A JP2007556275A JP2007556275A JP2008530225A JP 2008530225 A JP2008530225 A JP 2008530225A JP 2007556275 A JP2007556275 A JP 2007556275A JP 2007556275 A JP2007556275 A JP 2007556275A JP 2008530225 A JP2008530225 A JP 2008530225A
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- Prior art keywords
- compound
- azabicyclo
- ethyl
- indazole
- salt
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- FHUPHXAYPNYFIU-UHFFFAOYSA-N 1-propan-2-ylindazole-3-carboxylic acid Chemical compound C1=CC=C2N(C(C)C)N=C(C(O)=O)C2=C1 FHUPHXAYPNYFIU-UHFFFAOYSA-N 0.000 claims abstract description 47
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65367705P | 2005-02-17 | 2005-02-17 | |
| PCT/US2006/005399 WO2006088988A1 (en) | 2005-02-17 | 2006-02-16 | Crystalline form of an indazole-carboxamide compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008530225A true JP2008530225A (ja) | 2008-08-07 |
| JP2008530225A5 JP2008530225A5 (enExample) | 2009-03-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2007556275A Pending JP2008530225A (ja) | 2005-02-17 | 2006-02-16 | インダゾール−カルボキサミド化合物の結晶型 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20060183901A1 (enExample) |
| EP (1) | EP1848716A1 (enExample) |
| JP (1) | JP2008530225A (enExample) |
| TW (1) | TW200640921A (enExample) |
| WO (1) | WO2006088988A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI377206B (en) | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| GB0525068D0 (en) | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
| ATE509021T1 (de) * | 2006-02-16 | 2011-05-15 | Theravance Inc | Verfahren zur herstellung von zwischenverbindungen zu 5-ht4-rezeptoragonist- verbindungen |
| WO2010022052A1 (en) * | 2008-08-19 | 2010-02-25 | Scinopharm Taiwan, Ltd. | Polymorphic form of granisetron hydrochloride and methods of making the same |
| US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
| AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
| EP2531510B1 (en) | 2010-02-01 | 2014-07-23 | Novartis AG | Pyrazolo[5,1b]oxazole derivatives as crf-1 receptor antagonists |
| ES2527849T3 (es) | 2010-02-02 | 2015-01-30 | Novartis Ag | Derivados de ciclohexilamida como antagonistas del receptor de CRF |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001518504A (ja) * | 1997-10-07 | 2001-10-16 | イーライ・リリー・アンド・カンパニー | ５ｈｔ４作動薬および拮抗薬 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937247A (en) * | 1985-04-27 | 1990-06-26 | Beecham Group P.L.C. | 1-acyl indazoles |
| IT1226389B (it) * | 1988-07-12 | 1991-01-15 | Angeli Inst Spa | Nuovi derivati ammidinici e guanidinici |
| JP3829879B2 (ja) * | 1994-05-18 | 2006-10-04 | 大正製薬株式会社 | キノリンカルボン酸誘導体 |
| US5654320A (en) * | 1995-03-16 | 1997-08-05 | Eli Lilly And Company | Indazolecarboxamides |
| IT1291569B1 (it) * | 1997-04-15 | 1999-01-11 | Angelini Ricerche Spa | Indazolammidi come agenti serotoninergici |
| TW200533348A (en) * | 2004-02-18 | 2005-10-16 | Theravance Inc | Indazole-carboxamide compounds as 5-ht4 receptor agonists |
| WO2006069125A1 (en) * | 2004-12-22 | 2006-06-29 | Theravance, Inc. | Indazole-carboxamide compounds |
-
2006
- 2006-02-16 JP JP2007556275A patent/JP2008530225A/ja active Pending
- 2006-02-16 EP EP06735182A patent/EP1848716A1/en not_active Withdrawn
- 2006-02-16 WO PCT/US2006/005399 patent/WO2006088988A1/en not_active Ceased
- 2006-02-16 TW TW095105173A patent/TW200640921A/zh unknown
- 2006-02-16 US US11/355,323 patent/US20060183901A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001518504A (ja) * | 1997-10-07 | 2001-10-16 | イーライ・リリー・アンド・カンパニー | ５ｈｔ４作動薬および拮抗薬 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1848716A1 (en) | 2007-10-31 |
| TW200640921A (en) | 2006-12-01 |
| US20060183901A1 (en) | 2006-08-17 |
| WO2006088988A1 (en) | 2006-08-24 |
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