JP2008526893A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008526893A5 JP2008526893A5 JP2007550575A JP2007550575A JP2008526893A5 JP 2008526893 A5 JP2008526893 A5 JP 2008526893A5 JP 2007550575 A JP2007550575 A JP 2007550575A JP 2007550575 A JP2007550575 A JP 2007550575A JP 2008526893 A5 JP2008526893 A5 JP 2008526893A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- inhalable
- inhalable pharmaceutical
- patient
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64305405P | 2005-01-10 | 2005-01-10 | |
| PCT/US2006/000910 WO2006086107A2 (en) | 2005-01-10 | 2006-01-10 | Methods and compositions for minimizing accrual of inhalable insulin in the lungs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008526893A JP2008526893A (ja) | 2008-07-24 |
| JP2008526893A5 true JP2008526893A5 (https=) | 2009-03-05 |
Family
ID=36793549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007550575A Withdrawn JP2008526893A (ja) | 2005-01-10 | 2006-01-10 | 肺における吸入可能なインスリンの自然増加を最少化するための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060153778A1 (https=) |
| EP (1) | EP1858486A2 (https=) |
| JP (1) | JP2008526893A (https=) |
| AU (1) | AU2006213084A1 (https=) |
| CA (1) | CA2592776A1 (https=) |
| MX (1) | MX2007008379A (https=) |
| WO (1) | WO2006086107A2 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| ES2569916T3 (es) | 1999-06-29 | 2016-05-13 | Mannkind Corporation | Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| US20070027063A1 (en) * | 2004-01-12 | 2007-02-01 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| AU2014271222B2 (en) * | 2005-09-14 | 2016-04-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| EP2211842B1 (en) * | 2007-10-24 | 2015-08-12 | MannKind Corporation | An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration |
| US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
| US8485180B2 (en) * | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| US20190262557A1 (en) * | 2010-03-04 | 2019-08-29 | Mannkind Corporation | Dry powder drug delivery system |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| US11110151B2 (en) * | 2008-08-11 | 2021-09-07 | Mannkind Corporation | Composition and method for reducing hypoglycemia events in diabetes treatment |
| TWI532497B (zh) * | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DK2379100T3 (en) * | 2009-01-08 | 2014-12-01 | Mannkind Corp | Treatment of hyperglycemia with GLP-1 |
| AU2014200960B2 (en) * | 2009-03-04 | 2016-02-11 | Mannkind Corporation | An improved dry powder drug delivery system |
| CN102438602B (zh) * | 2009-03-04 | 2016-04-13 | 曼金德公司 | 改进的干燥粉末药物输送系统 |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| KR102584844B1 (ko) * | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| EP3556356B1 (en) * | 2009-06-12 | 2021-05-05 | MannKind Corporation | Diketopiperazine microparticles with defined isomer content |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2000301A (en) * | 1932-04-02 | 1935-05-07 | Norman Confections Inc | Progressive container |
| US5352461A (en) * | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5547929A (en) * | 1994-09-12 | 1996-08-20 | Eli Lilly And Company | Insulin analog formulations |
| US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
| ES2569916T3 (es) * | 1999-06-29 | 2016-05-13 | Mannkind Corporation | Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina |
| ES2584867T3 (es) * | 2004-01-12 | 2016-09-29 | Mannkind Corporation | Un método que reduce los niveles séricos de proinsulina en diabéticos de tipo 2 |
-
2006
- 2006-01-10 EP EP06748159A patent/EP1858486A2/en not_active Withdrawn
- 2006-01-10 US US11/330,427 patent/US20060153778A1/en not_active Abandoned
- 2006-01-10 MX MX2007008379A patent/MX2007008379A/es unknown
- 2006-01-10 JP JP2007550575A patent/JP2008526893A/ja not_active Withdrawn
- 2006-01-10 CA CA002592776A patent/CA2592776A1/en not_active Abandoned
- 2006-01-10 WO PCT/US2006/000910 patent/WO2006086107A2/en not_active Ceased
- 2006-01-10 AU AU2006213084A patent/AU2006213084A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008526893A5 (https=) | ||
| Shankar et al. | Isoflurane therapy for severe refractory status asthmaticus in children | |
| Diaz et al. | Delivery and safety of inhaled interferon-γ in idiopathic pulmonary fibrosis | |
| JP2008534622A5 (https=) | ||
| MX2023001592A (es) | Inhalador de polvo seco. | |
| JP2015110631A5 (https=) | ||
| JP2011500850A5 (https=) | ||
| JP2010522212A5 (https=) | ||
| YU36302A (sh) | Novi tiotropiumski preparati - koji sadrže prah za inhaliranje | |
| AR067639A1 (es) | Medicamentos pulverulentos que contienen tiotropio y salmetrol, asi como lactosa como excipiente | |
| WO2006059108A3 (en) | ANTI-IL-IRl SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC USES | |
| UA101653C2 (uk) | Композиція для інгаляції, що містить аклідиній для лікування астми та хронічного обструктивного захворювання легень | |
| MXPA03011861A (es) | Particulas para inhalacion que tienen rapidas propiedades de liberacion. | |
| UA101652C2 (uk) | Композиція для інгаляції, що містить аклідиній для лікування астми та хронічного обструктивного захворювання легень | |
| JP2007520506A5 (https=) | ||
| JP2007520507A5 (https=) | ||
| Eden et al. | Prolonged smoldering Douglas fir smoke inhalation augments respiratory resistances, stiffens the aorta, and curbs ejection fraction in hypercholesterolemic mice | |
| Brain | Unlocking the opportunity of tight glycaemic control: Inhaled insulin: safety | |
| CN102133319B (zh) | 一种平喘止咳的药物及其制备方法 | |
| BR0316343A (pt) | Formulações pulverulentas para inalação contendo tiotrópio | |
| Berkowitz et al. | Laryngeal foreign bodies in children revisited | |
| ATE339951T1 (de) | Pulverzubereitungen zur inhalation | |
| Trakada et al. | A case of ischemic hepatitis | |
| Araújo et al. | Transitory increased blood pressure after upper airway surgery for snoring and sleep apnea correlates with the apnea-hypopnea respiratory disturbance index | |
| Chattopadhyay et al. | Respiratory response to tobacco dust exposure among biddi binders: A follow up and bronchodilator study |