JP2008524409A5 - - Google Patents

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Publication number

JP2008524409A5

JP2008524409A5 JP2007547247A JP2007547247A JP2008524409A5 JP 2008524409 A5 JP2008524409 A5 JP 2008524409A5 JP 2007547247 A JP2007547247 A JP 2007547247A JP 2007547247 A JP2007547247 A JP 2007547247A JP 2008524409 A5 JP2008524409 A5 JP 2008524409A5

Authority

JP

Japan

Prior art keywords

hydrogen

alkyl

independently

polycarbonate

phenyl

Prior art date

2005-12-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 229910052739 hydrogen Inorganic materials 0.000 claims 8
• 239000001257 hydrogen Substances 0.000 claims 8
• 150000002431 hydrogen Chemical class 0.000 claims 6
• 229920000515 polycarbonate Polymers 0.000 claims 5
• 239000004417 polycarbonate Substances 0.000 claims 5
• CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 4
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
• -1 trimethylcyclohexyl Chemical group 0.000 claims 4
• HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
• 229910052799 carbon Inorganic materials 0.000 claims 3
• 125000004432 carbon atom Chemical group C* 0.000 claims 3
• 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 3
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
• AKZWRTCWNXHHFR-PDIZUQLASA-N [(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(5S)-5-benzyl-3-[(2R)-2-carbamoyloxy-2,3-dihydro-1H-inden-1-yl]-4-oxo-3H-pyrrol-5-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate Chemical compound NC(=O)O[C@@H]1Cc2ccccc2C1C1C=N[C@](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)O[C@H]2CCOC2)(Cc2ccccc2)C1=O AKZWRTCWNXHHFR-PDIZUQLASA-N 0.000 claims 1
• 238000005904 alkaline hydrolysis reaction Methods 0.000 claims 1
• 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
• 230000005686 electrostatic field Effects 0.000 claims 1
• 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
• 238000004128 high performance liquid chromatography Methods 0.000 claims 1
• 238000002347 injection Methods 0.000 claims 1
• 239000007924 injection Substances 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
• 229920005668 polycarbonate resin Polymers 0.000 claims 1
• 239000004431 polycarbonate resin Substances 0.000 claims 1
• 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
• 239000000243 solution Substances 0.000 claims 1
• 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1