JP2008522162A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008522162A5 JP2008522162A5 JP2007543518A JP2007543518A JP2008522162A5 JP 2008522162 A5 JP2008522162 A5 JP 2008522162A5 JP 2007543518 A JP2007543518 A JP 2007543518A JP 2007543518 A JP2007543518 A JP 2007543518A JP 2008522162 A5 JP2008522162 A5 JP 2008522162A5
- Authority
- JP
- Japan
- Prior art keywords
- mer
- molecular weight
- tyrosine kinase
- receptor tyrosine
- transmembrane receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63019204P | 2004-11-24 | 2004-11-24 | |
| PCT/US2005/042724 WO2006058202A2 (en) | 2004-11-24 | 2005-11-23 | Mer diagnostic and therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008522162A JP2008522162A (ja) | 2008-06-26 |
| JP2008522162A5 true JP2008522162A5 (https=) | 2009-01-15 |
Family
ID=36498546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543518A Pending JP2008522162A (ja) | 2004-11-24 | 2005-11-23 | Ｍｅｒの診断用および治療用の作用薬 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20080267975A1 (https=) |
| EP (1) | EP1825005B1 (https=) |
| JP (1) | JP2008522162A (https=) |
| CA (1) | CA2630475A1 (https=) |
| WO (1) | WO2006058202A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2555763A1 (en) * | 2004-01-29 | 2005-08-11 | Asahi Kasei Pharma Corporation | Therapeutic agent for vasospasm accompanying bypass operation |
| WO2008098139A2 (en) | 2007-02-07 | 2008-08-14 | The Regents Of The University Of Colorado | Axl tyrosine kinase inhibitors and methods of making and using the same |
| CA2786149C (en) * | 2010-01-22 | 2019-11-12 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of axl signaling in anti-metastatic therapy |
| WO2012149018A1 (en) * | 2011-04-25 | 2012-11-01 | The Regents Of The University Of Colorado | Mer tyrosine kinase inhibitors and methods of making and using the same |
| WO2013090776A1 (en) | 2011-12-15 | 2013-06-20 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of axl/gas6 signaling in the treatment of disease |
| PT3326622T (pt) | 2012-12-14 | 2021-04-07 | Univ Leland Stanford Junior | Péptidos axl modificados e sua utilização na inibição da sinalização de axl em terapêutica anti-metastática |
| KR20150040766A (ko) * | 2013-10-07 | 2015-04-15 | 이화여자대학교 산학협력단 | 항염증 물질을 스크리닝하는 방법 |
| US10137173B2 (en) | 2014-10-20 | 2018-11-27 | Aravive Biologics, Inc. | Antiviral activity of Gas6 inhibitor |
| JP7211703B2 (ja) | 2014-12-22 | 2023-01-24 | ザ ロックフェラー ユニバーシティー | 抗ｍｅｒｔｋアゴニスト抗体及びその使用 |
| JP2020526584A (ja) | 2017-06-28 | 2020-08-31 | ザ ロックフェラー ユニバーシティー | 抗ｍｅｒｔｋアゴニスト抗体−薬物コンジュゲートおよびその使用 |
| JP2023506465A (ja) | 2019-12-13 | 2023-02-16 | アレクトル エルエルシー | 抗ＭｅｒＴＫ抗体及びその使用方法 |
| CN111812014B (zh) * | 2020-08-05 | 2023-04-18 | 上海市血液中心 | 一种基于纳米材料的血小板抗体检测方法和血小板保存方法 |
| CA3217372A1 (en) * | 2021-05-14 | 2022-11-17 | Masoud TAVAZOIE | Mertk peptides and uses thereof |
| JP2024527493A (ja) | 2021-06-16 | 2024-07-25 | アレクトル エルエルシー | 一価の抗ＭｅｒＴＫ抗体及びその使用方法 |
| US20240279341A1 (en) | 2021-06-16 | 2024-08-22 | Alector Llc | Bispecific anti-mertk and anti-pdl1 antibodies and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US6018026A (en) * | 1988-01-22 | 2000-01-25 | Zymogenetics, Inc. | Biologically active dimerized and multimerized polypeptide fusions |
| US5554601A (en) * | 1993-11-05 | 1996-09-10 | University Of Florida | Methods for neuroprotection |
| US5585269A (en) * | 1994-06-02 | 1996-12-17 | The University Of North Carolina At Chapel Hill | Isolated DNA encoding c-mer protooncogene |
| US20030166132A1 (en) * | 1998-08-26 | 2003-09-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030144237A1 (en) * | 2000-04-13 | 2003-07-31 | Peter Carmeliet | Use of inhibition of a gas6 function or of a gas6 receptor for preventing and treating a cardiovascular disease |
| US20040018513A1 (en) * | 2002-03-22 | 2004-01-29 | Downing James R | Classification and prognosis prediction of acute lymphoblastic leukemia by gene expression profiling |
| AU2003276958A1 (en) * | 2002-09-24 | 2004-04-19 | Centocor, Inc. | Epitope-tagged recombinant growth arrest specific gene 6 protein |
-
2005
- 2005-11-23 JP JP2007543518A patent/JP2008522162A/ja active Pending
- 2005-11-23 WO PCT/US2005/042724 patent/WO2006058202A2/en not_active Ceased
- 2005-11-23 EP EP05852182.4A patent/EP1825005B1/en not_active Expired - Lifetime
- 2005-11-23 US US11/720,185 patent/US20080267975A1/en not_active Abandoned
- 2005-11-23 CA CA002630475A patent/CA2630475A1/en not_active Abandoned
-
2011
- 2011-09-12 US US13/230,005 patent/US20120135424A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008522162A5 (https=) | ||
| Landoni et al. | Modifications to the framework regions eliminate chimeric antigen receptor tonic signaling | |
| JP2022104941A (ja) | ヒト化抗ｃｄ７３抗体 | |
| Roth et al. | Soluble decoy receptor 3 is expressed by malignant gliomas and suppresses CD95 ligand-induced apoptosis and chemotaxis | |
| Wright et al. | The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans | |
| TW438809B (en) | Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation | |
| Kamihira et al. | Aberrant expression of caspase cascade regulatory genes in adult T‐cell leukaemia: survivin is an important determinant for prognosis | |
| Shisler et al. | The adenovirus E3-10.4 K/14.5 K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis | |
| Williams et al. | Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis | |
| CN103459595B (zh) | 针对人前列腺素e2受体ep4的抗体 | |
| KR20200020662A (ko) | 면역-종양학 제제와 함께 ps-표적화 항체를 사용하여 암을 치료하는 방법 | |
| PT98394B (pt) | Processo para a preparacao de formas multimericas da proteina receptora de rinovirus humano | |
| CN111148514A (zh) | 与免疫调节剂联合应用于癌症免疫治疗的rar选择性激动剂 | |
| JP2013520171A (ja) | Ｗｎｔシグナル伝達経路を阻害するモノクローナル抗体ならびにその製造方法およびその使用方法 | |
| KR20140054238A (ko) | 인테그린 알파-v 베타-8에 결합하는 항체 | |
| CN109563154B (zh) | 抗帕多瓦因子ix抗体 | |
| US11911404B2 (en) | Fucosylation and immune surveillance in melanoma | |
| Yard et al. | Decreased glomerular expression of agrin in diabetic nephropathy and podocytes, cultured in high glucose medium | |
| Horváth et al. | IgA autoantibodies in the pemphigoids and linear IgA bullous dermatosis | |
| PT1079843E (pt) | Utilização dos inibidores do receptor de integrina 1 1 e dos inibidores de fct- 1 no tratamento de doenças do rim | |
| KR20240112996A (ko) | Hpv16 e7 항원을 인식하는 결합 단백질 및 이의 용도 | |
| JP2010525795A (ja) | オステオポンチンの機能エピトープ、それと特異的に結合するモノクローナル抗体およびその抗腫瘍薬の製造のための用途 | |
| Chang | Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1 | |
| Craig et al. | Failure to block adhesion of Plasmodium falciparum-infected erythrocytes to ICAM-1 with soluble ICAM-1 | |
| Pinkert et al. | The coxsackievirus and adenovirus receptor: glycosylation and the extracellular D2 domain are not required for coxsackievirus B3 infection |