JP2008520717A - 多発性硬化症についての処置 - Google Patents

多発性硬化症についての処置 Download PDF

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Publication number
JP2008520717A
JP2008520717A JP2007543322A JP2007543322A JP2008520717A JP 2008520717 A JP2008520717 A JP 2008520717A JP 2007543322 A JP2007543322 A JP 2007543322A JP 2007543322 A JP2007543322 A JP 2007543322A JP 2008520717 A JP2008520717 A JP 2008520717A
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JP
Japan
Prior art keywords
vla
subject
antibody
agent
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007543322A
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English (en)
Japanese (ja)
Other versions
JP2008520717A5 (https=
Inventor
マイケル パンザラ，
アルフレッド サンドロック，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Biogen MA Inc
Original Assignee
Biogen Inc
Biogen Idec Inc
Biogen Idec MA Inc
Biogen MA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, Biogen Idec Inc, Biogen Idec MA Inc, Biogen MA Inc filed Critical Biogen Inc
Publication of JP2008520717A publication Critical patent/JP2008520717A/ja
Publication of JP2008520717A5 publication Critical patent/JP2008520717A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2007543322A 2004-11-19 2005-11-18 多発性硬化症についての処置 Pending JP2008520717A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62970004P 2004-11-19 2004-11-19
PCT/US2005/042052 WO2006055871A2 (en) 2004-11-19 2005-11-18 Treatment for multiple sclerosis

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2008294839A Division JP2009091360A (ja) 2004-11-19 2008-11-18 多発性硬化症についての処置
JP2012188532A Division JP2012233009A (ja) 2004-11-19 2012-08-29 多発性硬化症についての処置

Publications (2)

Publication Number Publication Date
JP2008520717A true JP2008520717A (ja) 2008-06-19
JP2008520717A5 JP2008520717A5 (https=) 2009-01-15

Family

ID=36407818

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2007543322A Pending JP2008520717A (ja) 2004-11-19 2005-11-18 多発性硬化症についての処置
JP2008294839A Pending JP2009091360A (ja) 2004-11-19 2008-11-18 多発性硬化症についての処置
JP2012188532A Pending JP2012233009A (ja) 2004-11-19 2012-08-29 多発性硬化症についての処置
JP2014247885A Pending JP2015044873A (ja) 2004-11-19 2014-12-08 多発性硬化症についての処置

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2008294839A Pending JP2009091360A (ja) 2004-11-19 2008-11-18 多発性硬化症についての処置
JP2012188532A Pending JP2012233009A (ja) 2004-11-19 2012-08-29 多発性硬化症についての処置
JP2014247885A Pending JP2015044873A (ja) 2004-11-19 2014-12-08 多発性硬化症についての処置

Country Status (8)

Country Link
US (1) US20090202527A1 (https=)
EP (2) EP2808033A1 (https=)
JP (4) JP2008520717A (https=)
CN (2) CN103169965A (https=)
AU (1) AU2005306399B2 (https=)
CA (1) CA2587597A1 (https=)
HK (1) HK1203055A1 (https=)
WO (1) WO2006055871A2 (https=)

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DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
CA2526586C (en) 2003-09-09 2010-03-16 Biogen International Gmbh The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
NZ581497A (en) * 2004-12-03 2012-07-27 Biogen Idec Inc Delaying or preventing onset of multiple sclerosis by vla-4 ginding antibody
EP2680010A1 (en) 2007-02-08 2014-01-01 Biogen Idec MA Inc. Nrf2 screening assays and related methods and compositions
NZ595526A (en) * 2007-06-14 2013-03-28 Biogen Idec Inc Pharmaceutical composition comprising a vla-4 binding antibody, a phosphate buffer and a surfactant
HRP20171045T1 (hr) * 2010-04-16 2017-10-06 Biogen Ma Inc. Protutijela anti-vla-4
AU2014285086A1 (en) * 2013-07-05 2016-01-21 Biogen Ma Inc. Compositions and methods for treatment of stroke
WO2016145389A1 (en) 2015-03-12 2016-09-15 Board Of Trustees Of Michigan State University Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
CN116769054A (zh) 2016-02-05 2023-09-19 奥里尼斯生物科学私人有限公司 双特异性信号传导剂及其用途
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
CN109982712A (zh) 2016-08-31 2019-07-05 Mapi医药公司 包含醋酸格拉替雷的储库系统
CN110573172A (zh) 2017-02-06 2019-12-13 奥里尼斯生物科学有限公司 靶向的工程化干扰素及其用途
KR102642385B1 (ko) 2017-02-06 2024-03-04 오리오니스 바이오사이언시스 엔브이 표적화된 키메라 단백질 및 이의 용도
CN110382052A (zh) 2017-03-26 2019-10-25 Mapi医药公司 用于治疗进展型形式的多发性硬化症的格拉替雷储库系统
MA49645A (fr) 2017-07-20 2021-03-31 Univ Virginia Patent Foundation Procédés de traitement ou de prévention d'un trouble neurologique du système immunitaire
EP3743448A4 (en) 2018-01-26 2021-11-03 Orionis Biosciences, Inc. XCR1 BINDING AGENTS AND USES THEREOF
CN119080931A (zh) 2018-06-04 2024-12-06 马萨诸塞州渤健公司 具有降低的效应功能的抗vla-4抗体
US12410225B2 (en) 2018-11-08 2025-09-09 Orionis Biosciences, Inc Modulation of dendritic cell lineages
MA54752A (fr) * 2019-01-14 2021-11-24 Univ Virginia Patent Foundation Utilisation d'inhibiteurs d'intégrine pour le traitement ou la prévention d'un trouble immunitaire neurologique et/ou d'une lésion du système nerveux

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Also Published As

Publication number Publication date
JP2015044873A (ja) 2015-03-12
WO2006055871A3 (en) 2006-08-03
WO2006055871A2 (en) 2006-05-26
JP2012233009A (ja) 2012-11-29
JP2009091360A (ja) 2009-04-30
HK1203055A1 (en) 2015-10-16
CA2587597A1 (en) 2006-05-26
EP2808033A1 (en) 2014-12-03
EP1827491A2 (en) 2007-09-05
CN101102792A (zh) 2008-01-09
AU2005306399A1 (en) 2006-05-26
CN103169965A (zh) 2013-06-26
AU2005306399B2 (en) 2012-02-09
US20090202527A1 (en) 2009-08-13
EP1827491A4 (en) 2010-07-14

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