JP2008520710A5 - - Google Patents
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- Publication number
- JP2008520710A5 JP2008520710A5 JP2007543291A JP2007543291A JP2008520710A5 JP 2008520710 A5 JP2008520710 A5 JP 2008520710A5 JP 2007543291 A JP2007543291 A JP 2007543291A JP 2007543291 A JP2007543291 A JP 2007543291A JP 2008520710 A5 JP2008520710 A5 JP 2008520710A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- lack
- effective amount
- pharmaceutical composition
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62995804P | 2004-11-22 | 2004-11-22 | |
| US60/629,958 | 2004-11-22 | ||
| PCT/US2005/041888 WO2006057915A2 (en) | 2004-11-22 | 2005-11-18 | 2-methylene-19,21-dinor-1alpha-hydroxy-bishomopregnacalciferol |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008520710A JP2008520710A (ja) | 2008-06-19 |
| JP2008520710A5 true JP2008520710A5 (https=) | 2009-01-15 |
| JP5036548B2 JP5036548B2 (ja) | 2012-09-26 |
Family
ID=36498437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543291A Expired - Fee Related JP5036548B2 (ja) | 2004-11-22 | 2005-11-18 | ２−メチレン−１９，２１−ジノル−１α−ヒドロキシ−ビスホモプレグナカルシフェロール |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8604008B2 (https=) |
| EP (1) | EP1827452B1 (https=) |
| JP (1) | JP5036548B2 (https=) |
| AT (1) | ATE499942T1 (https=) |
| AU (1) | AU2005309820B2 (https=) |
| CA (1) | CA2588063C (https=) |
| DE (1) | DE602005026694D1 (https=) |
| ES (1) | ES2358914T3 (https=) |
| MX (1) | MX2007006094A (https=) |
| NZ (1) | NZ555561A (https=) |
| WO (1) | WO2006057915A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8222235B2 (en) * | 2004-11-22 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20R)-1α-hydroxy-bishomopregnacalciferol |
| EP1827452B1 (en) | 2004-11-22 | 2011-03-02 | Wisconsin Alumni Research Foundation | 2-methylene-19,21-dinor-1alpha-hydroxy-bishomopregnacalciferol |
| AU2012271759B2 (en) * | 2011-06-14 | 2017-02-02 | Wisconsin Alumni Research Foundation | 3-desoxy-2-methylene-19-nor-vitamin D analogs and their uses |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666634A (en) * | 1984-12-05 | 1987-05-19 | Chugai Seiyaku Kabushiki Kaisha | vitamin D3 derivatives having a substituent at 2-position |
| CA2062520C (en) | 1991-03-11 | 1998-08-11 | Hector F. Deluca | Synthesis of 1-alpha-hydroxy-secosterol compounds |
| US5086191A (en) * | 1991-05-28 | 1992-02-04 | Wisconsin Alumni Research Foundation | Intermediates for the synthesis of 19-nor vitamin D compounds |
| EP0619306B1 (en) | 1993-04-05 | 1996-09-11 | Wisconsin Alumni Research Foundation | 19-Nor-vitamin D3 compounds with substituent at 2-position |
| US5552392A (en) * | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
| US5891865A (en) * | 1996-10-04 | 1999-04-06 | Wisconsin Alumni Research Foundation | Treatment of arthritic disease induced by infectious agents |
| US6392071B1 (en) * | 1997-03-17 | 2002-05-21 | Wisconsin Alumni: Research Foundation | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds |
| US5945410A (en) | 1997-03-17 | 1999-08-31 | Wisconsin Alumni Research Foundation | 2-alkyl-19-nor-vitamin D compounds |
| US5843928A (en) * | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
| US5936105A (en) * | 1997-06-13 | 1999-08-10 | Tetrionics, Inc. | 14-EPI-19-nor-vitamin D compounds and methods |
| NZ524657A (en) * | 2000-09-08 | 2004-12-24 | Wisconsin Alumni Res Found | 1 alpha-hydroxy-2-methylene-19-nor-homopregnacalciferol and its therapeutic applications |
| US6627622B2 (en) * | 2002-02-18 | 2003-09-30 | Wisconsin Alumni Research Foundation | (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses |
| NZ533424A (en) * | 2001-12-13 | 2006-08-31 | Wisconsin Alumni Res Found | Vitamin D derivative, methods of purifying and uses in treating psoriasis, cancer, autoimmune diseases, inflammatory diseases, skin conidtions and renal ostepdystrophy |
| US6835723B2 (en) * | 2001-12-13 | 2004-12-28 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-20(S)-1α-hydroxy-bis-homo-pregnacalciferol in crystalline form |
| US6566352B1 (en) * | 2002-02-18 | 2003-05-20 | Wisconsin Alumni Research Foudation | 1 α-hydroxy-2-methylene-19-nor-pregnacalciferol and its uses |
| HK1079766B (zh) * | 2002-03-29 | 2007-05-25 | 威斯康星校友研究基金会 | 合成1α-羟基-2-亚甲基-19-去甲-高孕钙化醇的方法 |
| AU2004266706B2 (en) * | 2003-08-20 | 2009-07-30 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-vitamin D2 compounds |
| MXPA06005887A (es) * | 2003-11-25 | 2006-06-27 | Wisconsin Alumni Res Found | Analogos de vitamina d para la prevencion y el tratamiento de la obesidad. |
| EP1827452B1 (en) | 2004-11-22 | 2011-03-02 | Wisconsin Alumni Research Foundation | 2-methylene-19,21-dinor-1alpha-hydroxy-bishomopregnacalciferol |
| EP1828115A4 (en) * | 2004-11-22 | 2010-05-05 | Wisconsin Alumni Res Found | 2-METHYLENE-19-NOR (20S) -1ALPHA-HYDROXYTRISHOMOPREGNACALCIFEROL |
| CA2588399A1 (en) * | 2004-11-22 | 2006-06-01 | Wisconsin Alumni Research Foundation | 2alpha-methyl-19-nor-(20s)-1alpha-hydroxy-bishomopregnacalciferol and its uses |
| US8222235B2 (en) * | 2004-11-22 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(20R)-1α-hydroxy-bishomopregnacalciferol |
| US7718638B2 (en) * | 2007-12-28 | 2010-05-18 | Wisconsin Alumni Research Foundation | (20R)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin D analogs |
| WO2009086436A1 (en) * | 2007-12-28 | 2009-07-09 | Wisconsin Alumni Research Foundation | (20s)-23,23-difluoro-2-methylene-19-nor-bishomopregnacalciferol-vitamin d analogs |
-
2005
- 2005-11-18 EP EP05849207A patent/EP1827452B1/en not_active Expired - Lifetime
- 2005-11-18 DE DE602005026694T patent/DE602005026694D1/de not_active Expired - Lifetime
- 2005-11-18 US US11/283,541 patent/US8604008B2/en not_active Expired - Fee Related
- 2005-11-18 WO PCT/US2005/041888 patent/WO2006057915A2/en not_active Ceased
- 2005-11-18 AT AT05849207T patent/ATE499942T1/de not_active IP Right Cessation
- 2005-11-18 ES ES05849207T patent/ES2358914T3/es not_active Expired - Lifetime
- 2005-11-18 AU AU2005309820A patent/AU2005309820B2/en not_active Ceased
- 2005-11-18 CA CA2588063A patent/CA2588063C/en not_active Expired - Fee Related
- 2005-11-18 MX MX2007006094A patent/MX2007006094A/es active IP Right Grant
- 2005-11-18 JP JP2007543291A patent/JP5036548B2/ja not_active Expired - Fee Related
- 2005-11-18 NZ NZ555561A patent/NZ555561A/en not_active IP Right Cessation
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