JP2008519047A - 癌処置 - Google Patents

癌処置 Download PDF

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Publication number
JP2008519047A
JP2008519047A JP2007540086A JP2007540086A JP2008519047A JP 2008519047 A JP2008519047 A JP 2008519047A JP 2007540086 A JP2007540086 A JP 2007540086A JP 2007540086 A JP2007540086 A JP 2007540086A JP 2008519047 A JP2008519047 A JP 2008519047A
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JP
Japan
Prior art keywords
bendamustine
cancer
treatment
cells
cell
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2007540086A
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English (en)
Japanese (ja)
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JP2008519047A5 (https=
Inventor
ベンドール，ヘザー・ヘレン
エリオツト，ゲイリー・テイ
レオニ，ロレンゾ・エム
ニーマイヤー，クリステイナ・キヤロル
マルタニ，プラテイク・エス
Original Assignee
セフアロン・インコーポレーテツド
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36588320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2008519047(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by セフアロン・インコーポレーテツド filed Critical セフアロン・インコーポレーテツド
Publication of JP2008519047A publication Critical patent/JP2008519047A/ja
Publication of JP2008519047A5 publication Critical patent/JP2008519047A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007540086A 2004-11-05 2005-11-04 癌処置 Pending JP2008519047A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62519304P 2004-11-05 2004-11-05
US66022605P 2005-03-10 2005-03-10
PCT/US2005/040068 WO2006065392A2 (en) 2004-11-05 2005-11-04 Cancer treatments

Publications (2)

Publication Number Publication Date
JP2008519047A true JP2008519047A (ja) 2008-06-05
JP2008519047A5 JP2008519047A5 (https=) 2008-12-18

Family

ID=36588320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007540086A Pending JP2008519047A (ja) 2004-11-05 2005-11-04 癌処置

Country Status (12)

Country Link
US (2) US20060128777A1 (https=)
EP (1) EP1814544A4 (https=)
JP (1) JP2008519047A (https=)
CN (1) CN101933923A (https=)
AR (1) AR054094A1 (https=)
AU (1) AU2005317047A1 (https=)
CA (1) CA2585659A1 (https=)
CL (1) CL2009001721A1 (https=)
MX (1) MX2007005361A (https=)
NO (1) NO20072654L (https=)
TW (1) TW200621240A (https=)
WO (1) WO2006065392A2 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012503666A (ja) * 2008-09-25 2012-02-09 セファロン、インク． ベンダムスチン液体製剤
JP2012510483A (ja) * 2008-12-03 2012-05-10 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの固体投与剤
JP2012510484A (ja) * 2008-12-03 2012-05-10 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与剤
JP2012525387A (ja) * 2009-04-28 2012-10-22 セファロン、インク． ベンダムスチンの経口製剤
JP2013527206A (ja) * 2010-06-02 2013-06-27 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形及びその治療的使用
JP2013527207A (ja) * 2010-06-02 2013-06-27 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形
JP2014526503A (ja) * 2011-09-13 2014-10-06 ファーマサイクリックス，インク． ベンダムスチンと組み合わせたヒストンデアセチラーゼ阻害剤の製剤とその使用
US9186347B1 (en) 2003-04-07 2015-11-17 Pharmacyclics Llc Hydroxamates as therapeutic agents
US9421208B2 (en) 2013-08-02 2016-08-23 Pharmacyclics Llc Methods for the treatment of solid tumors

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US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US20090075967A1 (en) * 2007-09-15 2009-03-19 Protia, Llc Deuterium-enriched ceftriaxone
US20090082416A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched bendamustine
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
US8962614B2 (en) * 2008-04-17 2015-02-24 The Johns Hopkins University ON01910.Na enhances chemotherapeutic agent activity in drug-resistant tumors
ES2525257T3 (es) * 2009-02-25 2014-12-19 Supratek Pharma, Inc. Composiciones de ciclopolisacárido y de bendamustina
US8603521B2 (en) 2009-04-17 2013-12-10 Pharmacyclics, Inc. Formulations of histone deacetylase inhibitor and uses thereof
WO2010144675A1 (en) 2009-06-10 2010-12-16 Plus Chemicals Sa Polymorphs of bendamustine hcl and processes for preparation thereof
US8389558B2 (en) * 2009-07-20 2013-03-05 Supratek Pharma Inc. Bendamustine amphiphilic anionic compositions
SMT201700043T1 (it) 2010-01-28 2017-03-08 Eagle Pharmaceuticals Inc Formulazioni di bendamustina
US8383663B2 (en) 2010-07-19 2013-02-26 Supratek Pharma Inc. Bendamustine anionic-catioinic cyclopolysaccharide compositions
TW201306842A (zh) * 2011-06-15 2013-02-16 Exelixis Inc 使用ｐｉ３ｋ／ｍｔｏｒ吡啶並嘧啶酮抑制劑及苯達莫司汀及／或利妥昔單抗治療惡性血液疾病之組合療法
KR20140064873A (ko) 2011-08-16 2014-05-28 모르포시스 아게 항-cd19 항체 및 질소 머스타드를 사용한 조합 요법
EP2760842B1 (en) 2011-09-26 2016-11-16 Fresenius Kabi Oncology Ltd An improved process for the preparation of bendamustine hydrochloride
JP6250628B2 (ja) 2012-03-20 2017-12-20 イーグル・ファーマシューティカルズ・インコーポレーテッド ベンダムスチンの製剤
CN104271135B (zh) 2012-03-20 2017-05-17 赛多斯有限责任公司 在要求减少施用容量的患者中治疗苯达莫司汀响应性状况的方法
US10220051B2 (en) 2012-03-29 2019-03-05 Institute For Cancer Research Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
US8927516B2 (en) * 2012-03-29 2015-01-06 Institute For Cancer Research Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
US20150087681A1 (en) * 2013-09-25 2015-03-26 Pranav Patel Bendamustine HCL Stable Lyophilized Formulations
EP3052655B1 (en) 2013-09-30 2018-11-07 Institute For Cancer Research D/b/a The Research Institute of Fox Chase Cancer Center Closantel in combination with temozolomide for use in the treatment of a cancer in which is thymine dna glycosylase expressed
EP3116481A1 (en) * 2014-03-13 2017-01-18 Vasilios VOUDOURIS Bendamustine solid dispersions and continuous infusion
AU2016296905B2 (en) 2015-07-23 2018-07-05 Centre National De La Recherche Scientifique Use of a combination of Dbait molecule and parp inhibitors to treat cancer
GB201519573D0 (en) 2015-11-05 2015-12-23 King S College London Combination
WO2018162439A1 (en) 2017-03-08 2018-09-13 Onxeo New predictive biomarker for the sensitivity to a treatment of cancer with a dbait molecule
CA3092779A1 (en) 2018-03-13 2019-09-19 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
CN121398822A (zh) 2023-06-21 2026-01-23 四方生物科学有限公司 用于在治疗hr功能正常的癌症的方法中的用途的包含脱氧胞苷衍生物和parp抑制剂的组合

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186347B1 (en) 2003-04-07 2015-11-17 Pharmacyclics Llc Hydroxamates as therapeutic agents
JP2012503666A (ja) * 2008-09-25 2012-02-09 セファロン、インク． ベンダムスチン液体製剤
JP2012510483A (ja) * 2008-12-03 2012-05-10 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの固体投与剤
JP2012510484A (ja) * 2008-12-03 2012-05-10 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与剤
JP2015061864A (ja) * 2008-12-03 2015-04-02 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテルハフツング ベンダムスチンの固体投与剤
JP2017057225A (ja) * 2008-12-03 2017-03-23 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの固体投与剤
JP2012525387A (ja) * 2009-04-28 2012-10-22 セファロン、インク． ベンダムスチンの経口製剤
JP2016172763A (ja) * 2010-06-02 2016-09-29 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形及びその治療的使用
JP2013527206A (ja) * 2010-06-02 2013-06-27 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形及びその治療的使用
JP2013527207A (ja) * 2010-06-02 2013-06-27 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形
JP2016153438A (ja) * 2010-06-02 2016-08-25 アステラス ドイチュランド ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンダムスチンの経口投与形
JP2014526503A (ja) * 2011-09-13 2014-10-06 ファーマサイクリックス，インク． ベンダムスチンと組み合わせたヒストンデアセチラーゼ阻害剤の製剤とその使用
US9492423B2 (en) 2011-09-13 2016-11-15 Pharmacyclics Llc Formulations of histone deacetylase inhibitor in combination with bendamustine and uses thereof
US9421208B2 (en) 2013-08-02 2016-08-23 Pharmacyclics Llc Methods for the treatment of solid tumors

Also Published As

Publication number Publication date
AR054094A1 (es) 2007-06-06
US20090209606A1 (en) 2009-08-20
AU2005317047A1 (en) 2006-06-22
EP1814544A2 (en) 2007-08-08
WO2006065392A3 (en) 2006-12-21
CL2009001721A1 (es) 2010-02-19
WO2006065392A2 (en) 2006-06-22
EP1814544A4 (en) 2009-12-02
TW200621240A (en) 2006-07-01
WO2006065392A8 (en) 2007-03-01
CN101933923A (zh) 2011-01-05
CA2585659A1 (en) 2006-06-22
MX2007005361A (es) 2008-01-11
US20060128777A1 (en) 2006-06-15
NO20072654L (no) 2007-07-25

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