JP2008505190A5 - - Google Patents

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Publication number
JP2008505190A5
JP2008505190A5 JP2007527363A JP2007527363A JP2008505190A5 JP 2008505190 A5 JP2008505190 A5 JP 2008505190A5 JP 2007527363 A JP2007527363 A JP 2007527363A JP 2007527363 A JP2007527363 A JP 2007527363A JP 2008505190 A5 JP2008505190 A5 JP 2008505190A5
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JP
Japan
Prior art keywords
receptor
foreign compound
bone
administration
lrp5
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007527363A
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English (en)
Japanese (ja)
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JP2008505190A (ja
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Publication date
Priority claimed from US10/849,067 external-priority patent/US8637506B2/en
Application filed filed Critical
Publication of JP2008505190A publication Critical patent/JP2008505190A/ja
Publication of JP2008505190A5 publication Critical patent/JP2008505190A5/ja
Pending legal-status Critical Current

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JP2007527363A 2004-05-19 2005-05-18 骨の形成と再構築のための組成物および方法 Pending JP2008505190A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/849,067 US8637506B2 (en) 2003-09-22 2004-05-19 Compositions and methods for bone formation and remodeling
PCT/US2005/017199 WO2005115354A2 (en) 2004-05-19 2005-05-18 Compositions and methods for bone formation and remodeling

Publications (2)

Publication Number Publication Date
JP2008505190A JP2008505190A (ja) 2008-02-21
JP2008505190A5 true JP2008505190A5 (OSRAM) 2008-07-03

Family

ID=35451375

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007527363A Pending JP2008505190A (ja) 2004-05-19 2005-05-18 骨の形成と再構築のための組成物および方法

Country Status (7)

Country Link
US (1) US8637506B2 (OSRAM)
EP (3) EP1758562B1 (OSRAM)
JP (1) JP2008505190A (OSRAM)
CN (1) CN101316627A (OSRAM)
CA (6) CA2771951C (OSRAM)
IL (1) IL179241A (OSRAM)
WO (1) WO2005115354A2 (OSRAM)

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US20030219793A1 (en) * 2002-10-04 2003-11-27 Carulli John P. High bone mass gene of 11q13.3
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US8461155B2 (en) * 2003-09-22 2013-06-11 University Of Connecticut Sclerostin and the inhibition of WNT signaling and bone formation
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AR076668A1 (es) 2009-05-12 2011-06-29 Pfizer Anticuerpos especificos para dkk-1 y sus usos
EA201291181A1 (ru) 2010-05-06 2013-05-30 Новартис Аг Композиции и способы применения терапевтических поливалентных антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
CA2798432A1 (en) 2010-05-06 2011-11-10 Novartis Ag Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
US9493541B2 (en) 2010-06-07 2016-11-15 Joshua Rabbani Antibodies specific for sulfated sclerostin
US11167011B2 (en) 2010-06-07 2021-11-09 Enzo Biochem, Inc. Methods for treating bone loss using sclerostin peptides
US9403882B2 (en) 2010-06-07 2016-08-02 Joshua Rabbani Sulfation of Wnt pathway proteins
US9617323B2 (en) 2010-06-07 2017-04-11 Joshua Rabbani Sulfonated sclerostin, antibodies, epitopes and methods for identification and use therefor
JP5972283B2 (ja) * 2011-01-11 2016-08-17 フェイト セラピューティクス，インコーポレイテッド 新規のＷｎｔ組成物およびそのような組成物の治療的使用
KR101303941B1 (ko) 2011-03-31 2013-09-05 연세대학교 산학협력단 피마자 추출물을 유효성분으로 함유하는 골 질환 예방 및 치료용 조성물
KR20140091031A (ko) 2011-11-04 2014-07-18 노파르티스 아게 저밀도 지단백질-관련 단백질 6 (lrp6) - 반감기 연장제 구축물
CN103966229A (zh) * 2014-05-09 2014-08-06 中山大学 bbeAMP基因、其编码的蛋白质、以bbeAMP为目的基因生产的融合蛋白及其应用
EP3191526B1 (en) 2014-09-12 2023-02-22 The Board of Trustees of the Leland Stanford Junior University Wnt signaling agonist molecules
CN106367517A (zh) * 2016-09-28 2017-02-01 湖北工业大学 一种低密度脂蛋白受体相关蛋白5基因突变检测的试剂及应用
US11773171B2 (en) 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
JP7317016B2 (ja) 2017-12-19 2023-07-28 スロゼン オペレーティング， インコーポレイテッド 抗ｌｒｐ５／６抗体及び使用方法
JP7418332B2 (ja) 2017-12-19 2024-01-19 スロゼン オペレーティング， インコーポレイテッド 抗フリズルド抗体及び使用方法
CN111632147A (zh) * 2020-06-07 2020-09-08 重庆医科大学 骨细胞Wnt激活剂在制备骨折加速愈合、防治骨不连及不运动或失重骨丢失药物中的应用
EP4398990A4 (en) * 2021-09-08 2025-07-16 Baylor College Medicine METHODS AND COMPOSITIONS FOR IMMUNE REGULATION BY DICKKOPF-1
CN115309402B (zh) * 2022-07-13 2023-10-24 国网江苏省电力有限公司信息通信分公司 一种可量化差异的异构执行程序集合构成方法及装置

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US20040038860A1 (en) * 2002-05-17 2004-02-26 Allen Kristina M. Reagents and methods for modulating dkk-mediated interactions
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US20050084494A1 (en) 2003-05-21 2005-04-21 Darwin Prockop Inhibitors of Dkk-1
US8367822B2 (en) 2003-09-22 2013-02-05 Enzo Therapeutics, Inc. Compositions and methods for bone formation and remodeling
US8637506B2 (en) 2003-09-22 2014-01-28 Enzo Biochem, Inc. Compositions and methods for bone formation and remodeling
US20120178697A9 (en) 2003-09-22 2012-07-12 Jie Zheng Compositions and methods for the inhibition of dishevelled proteins
US9046537B2 (en) * 2003-09-22 2015-06-02 Enzo Biochem, Inc. Method for treating inflammation by administering a compound which binds LDL-receptor-related protein (LRP) ligand binding domain
US8461155B2 (en) 2003-09-22 2013-06-11 University Of Connecticut Sclerostin and the inhibition of WNT signaling and bone formation
US8343922B2 (en) 2004-05-19 2013-01-01 Enzo Biochem, Inc. Compositions and methods for the stimulation or enhancement of bone formation and the self-renewal of cells
CA2574881C (en) 2004-08-04 2013-01-08 Amgen Inc. Antibodies to dkk-1
US7838252B2 (en) 2005-02-17 2010-11-23 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating a subject having an anthrax toxin mediated condition

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