JP2008504228A5 - - Google Patents

Info

Publication number

JP2008504228A5

JP2008504228A5 JP2007505165A JP2007505165A JP2008504228A5 JP 2008504228 A5 JP2008504228 A5 JP 2008504228A5 JP 2007505165 A JP2007505165 A JP 2007505165A JP 2007505165 A JP2007505165 A JP 2007505165A JP 2008504228 A5 JP2008504228 A5 JP 2008504228A5

Authority

JP

Japan

Prior art keywords

compound

composition

inhibitor

pharmaceutical composition

ampk

Prior art date

2005-03-23

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 150000001875 compounds Chemical class 0.000 claims 6
• 239000003112 inhibitor Substances 0.000 claims 6
• 239000000203 mixture Substances 0.000 claims 5
• 102100036009 5'-AMP-activated protein kinase catalytic subunit alpha-2 Human genes 0.000 claims 4
• 101000783681 Homo sapiens 5'-AMP-activated protein kinase catalytic subunit alpha-2 Proteins 0.000 claims 4
• 239000008194 pharmaceutical composition Substances 0.000 claims 4
• LVTJOONKWUXEFR-FZRMHRINSA-N protoneodioscin Natural products O(C[C@@H](CC[C@]1(O)[C@H](C)[C@@H]2[C@]3(C)[C@H]([C@H]4[C@@H]([C@]5(C)C(=CC4)C[C@@H](O[C@@H]4[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@H](CO)O4)CC5)CC3)C[C@@H]2O1)C)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1 LVTJOONKWUXEFR-FZRMHRINSA-N 0.000 claims 2
• 239000012620 biological material Substances 0.000 claims 1
• 230000003727 cerebral blood flow Effects 0.000 claims 1
• 230000004112 neuroprotection Effects 0.000 claims 1
• 108090000765 processed proteins & peptides Proteins 0.000 claims 1
• 150000003384 small molecules Chemical class 0.000 claims 1