JP2008502699A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008502699A5 JP2008502699A5 JP2007516702A JP2007516702A JP2008502699A5 JP 2008502699 A5 JP2008502699 A5 JP 2008502699A5 JP 2007516702 A JP2007516702 A JP 2007516702A JP 2007516702 A JP2007516702 A JP 2007516702A JP 2008502699 A5 JP2008502699 A5 JP 2008502699A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- formoterol
- composition according
- dosage form
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 18
- 239000002552 dosage form Substances 0.000 claims 12
- BPZSYCZIITTYBL-UHFFFAOYSA-N formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-UHFFFAOYSA-N 0.000 claims 11
- 229960002848 formoterol Drugs 0.000 claims 11
- 102000005702 Calcium-Activated Potassium Channels Human genes 0.000 claims 10
- 108010045489 Calcium-Activated Potassium Channels Proteins 0.000 claims 10
- 239000004036 potassium channel stimulating agent Substances 0.000 claims 10
- 150000003839 salts Chemical class 0.000 claims 10
- 239000012453 solvate Substances 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 208000035475 disorder Diseases 0.000 claims 8
- 208000019693 Lung disease Diseases 0.000 claims 7
- 208000023504 respiratory system disease Diseases 0.000 claims 7
- 210000004072 lung Anatomy 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 230000000414 obstructive effect Effects 0.000 claims 4
- 206010006482 Bronchospasm Diseases 0.000 claims 3
- CTQURVKMWHDOKO-UHFFFAOYSA-N Dehydrosoyasaponin I Natural products CC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(OC3OC4CCC5(C)C(CCC6(C)C5CC=C7C8CC(C)(C)CC(=O)C8(C)CCC67C)C4(C)C=O)C(=O)O)C(O)C(O)C1O CTQURVKMWHDOKO-UHFFFAOYSA-N 0.000 claims 3
- CROUPKILZUPLQA-ITVSDQETSA-N Dehydrosoyasaponin I Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@@H](O[C@@H]([C@@H](O)[C@@H]2O)C(O)=O)O[C@@H]2[C@]([C@H]3[C@]([C@@H]4[C@@]([C@@]5(CC[C@@]6(C)C(=O)CC(C)(C)C[C@H]6C5=CC4)C)(C)CC3)(C)CC2)(C)CO)O[C@H](CO)[C@H](O)[C@@H]1O CROUPKILZUPLQA-ITVSDQETSA-N 0.000 claims 3
- 208000006673 asthma Diseases 0.000 claims 3
- 206010006451 bronchitis Diseases 0.000 claims 3
- 230000001684 chronic effect Effects 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 206010006458 Bronchitis chronic Diseases 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 2
- 206010014561 Emphysema Diseases 0.000 claims 2
- 208000004657 Exercise-Induced Asthma Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 206010035664 Pneumonia Diseases 0.000 claims 2
- BPZSYCZIITTYBL-YJYMSZOUSA-N R-Formoterol Chemical compound C1=CC(OC)=CC=C1C[C@@H](C)NC[C@H](O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-YJYMSZOUSA-N 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 208000007451 chronic bronchitis Diseases 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- 229940071648 metered dose inhaler Drugs 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- ZSUFQZNGDIXQAD-CABCVRRESA-N 1-[(3s,4r)-3-hydroxy-2,2-dimethyl-6-(1,1,2,2,2-pentafluoroethyl)-3,4-dihydrochromen-4-yl]piperidin-2-one Chemical compound N1([C@@H]2C3=CC(=CC=C3OC([C@H]2O)(C)C)C(F)(F)C(F)(F)F)CCCCC1=O ZSUFQZNGDIXQAD-CABCVRRESA-N 0.000 claims 1
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 206010003598 Atelectasis Diseases 0.000 claims 1
- KFFJPIQLAPHYBF-UHFFFAOYSA-N Azukisaponin V Natural products COC(=O)C1OC(OC2CCC3(C)C(CCC4(C)C3CC=C5C6CC(C)(C)CC(O)C6(O)CCC45C)C2(C)CO)C(OC7OC(CO)C(O)C(O)C7OC8OC(C)C(O)C(O)C8O)C(O)C1O KFFJPIQLAPHYBF-UHFFFAOYSA-N 0.000 claims 1
- 208000009079 Bronchial Spasm Diseases 0.000 claims 1
- 208000014181 Bronchial disease Diseases 0.000 claims 1
- 206010006448 Bronchiolitis Diseases 0.000 claims 1
- 206010006474 Bronchopulmonary aspergillosis allergic Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- -1 NS 004 Chemical compound 0.000 claims 1
- 208000007123 Pulmonary Atelectasis Diseases 0.000 claims 1
- 208000010378 Pulmonary Embolism Diseases 0.000 claims 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 claims 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 claims 1
- JFHRJMPZZYINAI-UHFFFAOYSA-N Soyasaponin I Natural products CC1OC(OC2C(O)C(O)C(CO)OC2OC3C(O)C(O)C(CO)OC3OC4CCC5(C)C(CCC6(C)C5CC=C7C8CC(C)(C)CC(O)C8(C)CCC67C)C4(C)CO)C(O)C(O)C1O JFHRJMPZZYINAI-UHFFFAOYSA-N 0.000 claims 1
- UZUYQJHHUUDLDJ-UHFFFAOYSA-N Soyasaponin III Natural products CC1(C)CC(O)C2(C)CCC3(C)C(=CCC4C5(C)CCC(OC6OC(CO)C(O)C(O)C6OC7OC(CO)C(O)C(O)C7O)C(C)(CO)C5CCC34C)C2C1 UZUYQJHHUUDLDJ-UHFFFAOYSA-N 0.000 claims 1
- 208000011341 adult acute respiratory distress syndrome Diseases 0.000 claims 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 claims 1
- 208000006778 allergic bronchopulmonary aspergillosis Diseases 0.000 claims 1
- 201000009267 bronchiectasis Diseases 0.000 claims 1
- 201000009580 eosinophilic pneumonia Diseases 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
- 201000003453 lung abscess Diseases 0.000 claims 1
- 238000009115 maintenance therapy Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 208000024696 nocturnal asthma Diseases 0.000 claims 1
- 230000002685 pulmonary effect Effects 0.000 claims 1
- 201000004193 respiratory failure Diseases 0.000 claims 1
- 230000002441 reversible effect Effects 0.000 claims 1
- PTDAHAWQAGSZDD-IOVCITQVSA-N soyasaponin I Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@H]2[C@@H](O[C@@H]([C@@H](O)[C@@H]2O)C(O)=O)O[C@@H]2[C@]([C@H]3[C@]([C@@H]4[C@@]([C@@]5(CC[C@@]6(C)[C@H](O)CC(C)(C)C[C@H]6C5=CC4)C)(C)CC3)(C)CC2)(C)CO)O[C@H](CO)[C@H](O)[C@@H]1O PTDAHAWQAGSZDD-IOVCITQVSA-N 0.000 claims 1
- OKIHRVKXRCAJFQ-AHBDIROXSA-N soyasaponin III Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@H]1O[C@H]1CC[C@]2(C)[C@H]3CC=C4[C@@]([C@@]3(CC[C@H]2[C@]1(CO)C)C)(C)CC[C@@]1(C)[C@H](O)CC(C[C@H]14)(C)C)C(O)=O)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O OKIHRVKXRCAJFQ-AHBDIROXSA-N 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57882804P | 2004-06-14 | 2004-06-14 | |
| US60729204P | 2004-09-07 | 2004-09-07 | |
| PCT/US2005/021209 WO2005123072A1 (en) | 2004-06-14 | 2005-06-14 | Methods and compositions for the treatment of pulmonary diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008502699A JP2008502699A (ja) | 2008-01-31 |
| JP2008502699A5 true JP2008502699A5 (enExample) | 2008-07-31 |
Family
ID=35509446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007516702A Abandoned JP2008502699A (ja) | 2004-06-14 | 2005-06-14 | 肺疾患治療方法、及びそのための組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080293788A1 (enExample) |
| EP (1) | EP1765331A4 (enExample) |
| JP (1) | JP2008502699A (enExample) |
| WO (1) | WO2005123072A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100015061A1 (en) * | 2006-01-06 | 2010-01-21 | Boehringer Ingeheim International GmnH | Pharmaceutical Compositions Based on Anticholinergics and Andolast |
| WO2008014814A1 (en) * | 2006-07-31 | 2008-02-07 | Rottapharm S.P.A. | Combination andolast/glucocorticoids |
| WO2009123241A1 (ja) | 2008-03-31 | 2009-10-08 | 株式会社レナサイエンス | プラスミノーゲンアクチベーターインヒビター－１阻害剤 |
| BRPI1013392A2 (pt) * | 2009-03-31 | 2016-03-29 | Renascience Co Ltd | inibidor do inibidor-1 do ativador do plasminogênio |
| JP2013056925A (ja) * | 2012-11-21 | 2013-03-28 | Rottapharm Spa | アンドラスト／グルココルチコイドの併用 |
| WO2014171464A1 (ja) | 2013-04-15 | 2014-10-23 | 株式会社レナサイエンス | Ｐａｉ－１阻害剤の新規用途 |
| GB202006074D0 (en) * | 2020-04-24 | 2020-06-10 | Vicore Pharma Ab | New composition |
| GB202006079D0 (en) | 2020-04-24 | 2020-06-10 | Vicore Pharma Ab | New composition |
| KR20240148359A (ko) | 2022-02-10 | 2024-10-11 | 바이코어 파마 아베 | 특발성 폐섬유증 치료를 위한 불록시부티드의 용도 |
| GB202201723D0 (en) * | 2022-02-10 | 2022-03-30 | Vicore Pharma Ab | New use |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2085468T3 (es) * | 1990-01-05 | 1996-06-01 | Sepracor Inc | Albuterol r(-) opticamente puro para tratar el asma. |
| US5200422A (en) * | 1990-09-24 | 1993-04-06 | Neurosearch A/S | Benzimidazole derivatives, their preparation and use |
| US5637470A (en) * | 1994-05-13 | 1997-06-10 | Merck & Co., Inc. | Screening array using cells expressing recombinant α and β subunits of the mammalian large-conductance (maxi-K) potassium channel |
| DE69722610T2 (de) * | 1997-08-08 | 2004-04-29 | Rotta Research Laboratorium S.P.A., Monza | Neue Inhalationspräparate enthaltend CR 2039 (Andolast) |
| CA2341488A1 (en) * | 1998-08-26 | 2000-03-09 | Smithkline Beecham Corporation | Therapies for treating pulmonary diseases |
| US6656461B1 (en) * | 2000-02-29 | 2003-12-02 | The Trustees Of Columbia University In The City Of New York | Therapeutic treatment of chronic obstructive pulmonary disease |
| GB0012261D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel process |
| US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| US7713964B2 (en) * | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
| TWI271402B (en) * | 2002-10-15 | 2007-01-21 | Tanabe Seiyaku Co | Large conductance calcium-activated K channel opener |
-
2005
- 2005-06-14 WO PCT/US2005/021209 patent/WO2005123072A1/en not_active Ceased
- 2005-06-14 US US11/629,687 patent/US20080293788A1/en not_active Abandoned
- 2005-06-14 JP JP2007516702A patent/JP2008502699A/ja not_active Abandoned
- 2005-06-14 EP EP05761013A patent/EP1765331A4/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Clarke et al. | Therapeutic aerosols 2--Drugs available by the inhaled route | |
| TWI278324B (en) | Dry powder for use in the preparation of medicament for the treatment of chronic obstructive pulmonary disease | |
| HRP20130052T1 (hr) | Lijeäśenje respiratorne bolesti | |
| ES2309705T3 (es) | Nueva combinacion de anticolinergico y beta-mimeticos para el tratamiento de enfermedades respiratorias. | |
| TWI758617B (zh) | 包含格隆銨鹽及茚達特羅鹽的氣霧劑藥物組合物、其製備方法與用途 | |
| JP2013224331A5 (enExample) | ||
| JP2014518268A5 (enExample) | ||
| JPH0648958A (ja) | 吸入による非ステロイド系抗炎症剤の抗反応抗喘息活性 | |
| RU2019100425A (ru) | Новая доза и препаративная форма | |
| JP2008536546A5 (enExample) | ||
| KR20110091505A (ko) | Ｃｏｐｄ 및 기타 폐질환의 치료 방법 | |
| US9861647B2 (en) | Calcium glycerophosphate for treating and preventing respiratory diseases or conditions | |
| JP2010508365A5 (enExample) | ||
| JP2008513444A (ja) | リドカイン及び他の局所麻酔剤の標的運搬並びに咳そう及び咳の発作の処置のための方法 | |
| WO2006065722A2 (en) | Compositions and methods for pulmonary conditions | |
| JP2020516689A5 (enExample) | ||
| JP2008502698A5 (enExample) | ||
| HRP20120286T1 (hr) | Kombinacija antikolinergika i inhibitora fosfodiesteraze tip 4 za liječenje respiratornih bolesti | |
| JP2022526367A5 (enExample) | ||
| CA2701388C (en) | Calcium glycerophosphate for treating and preventing respiratory diseases or conditions | |
| CN108472375A (zh) | 中重度流感的治疗方法 | |
| JP2013522295A5 (enExample) | ||
| KR20130140672A (ko) | 기침 치료용 카보네이트 유도체 | |
| WO2010009288A1 (en) | Compositions and uses of antiviral active pharmaceutical agents | |
| WO2007046113A3 (en) | Novel pharmaceutical composition comprising alkaloid and process thereof |