JP2008501656A - β−アミロイド（Ａβ４０及びＡβ４２）生成阻害のためのモノアミン神経伝達物質再取り込み阻害剤 - Google Patents
β−アミロイド（Ａβ４０及びＡβ４２）生成阻害のためのモノアミン神経伝達物質再取り込み阻害剤 Download PDFInfo
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- JP2008501656A JP2008501656A JP2007513821A JP2007513821A JP2008501656A JP 2008501656 A JP2008501656 A JP 2008501656A JP 2007513821 A JP2007513821 A JP 2007513821A JP 2007513821 A JP2007513821 A JP 2007513821A JP 2008501656 A JP2008501656 A JP 2008501656A
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- Prior art keywords
- tropane
- treatment
- prevention
- reuptake inhibitor
- alkyl
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04013242 | 2004-06-04 | ||
| PCT/EP2005/005748 WO2005117874A1 (en) | 2004-06-04 | 2005-05-28 | MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITOR FOR THE INHIBITION OF BETA-AMYLOID (Aß40 AND Aß42) -GENERATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008501656A true JP2008501656A (ja) | 2008-01-24 |
| JP2008501656A5 JP2008501656A5 (enExample) | 2008-06-19 |
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| JP2007513821A Abandoned JP2008501656A (ja) | 2004-06-04 | 2005-05-28 | β−アミロイド（Ａβ４０及びＡβ４２）生成阻害のためのモノアミン神経伝達物質再取り込み阻害剤 |
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| Country | Link |
|---|---|
| US (1) | US20050277664A1 (enExample) |
| EP (1) | EP1755602A1 (enExample) |
| JP (1) | JP2008501656A (enExample) |
| WO (1) | WO2005117874A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2019534295A (ja) * | 2016-11-08 | 2019-11-28 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | フェノキシトリアゾール |
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| ATE519486T1 (de) * | 2003-10-16 | 2011-08-15 | Neurosearch As | Pharmazeutische zusammensetzung mit einem monoamin-neurotransmitter-wiederaufnahmehemmer und einem acetylcholinesterase-hemmer |
| CA2554617A1 (en) * | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an n-methyl-d-aspartate (nmda) receptors antagonist |
| WO2005070427A1 (en) * | 2004-01-22 | 2005-08-04 | Neurosearch A/S | Compounds for the sustained reduction of body weight |
| WO2007028769A1 (en) * | 2005-09-05 | 2007-03-15 | Neurosearch A/S | Monoamine neurotransmitter re-uptake inhibitor for neuroprotection |
| GB2447191B (en) | 2005-12-22 | 2011-08-03 | Es Cell Int Pte Ltd | Direct differentiation of cardiomyocytes from human embryonic stem cells |
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| US2957693A (en) * | 1956-12-03 | 1960-10-25 | Arthur C Ross | Electrical robot dueler |
| US4934937A (en) * | 1988-12-14 | 1990-06-19 | Tommy Judd | Combat training system and apparatus |
| US5320358A (en) * | 1993-04-27 | 1994-06-14 | Rpb, Inc. | Shooting game having programmable targets and course for use therewith |
| US5599187A (en) * | 1994-12-21 | 1997-02-04 | Mesiano; Dominick N. | Firearm use training device and method |
| US5676548A (en) * | 1995-11-21 | 1997-10-14 | Mcalpin; Jim L. | Apparatus for target practice |
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| US20040106643A1 (en) * | 2001-05-23 | 2004-06-03 | Gouliaev Alex Haarh | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| US7250425B2 (en) * | 2003-02-12 | 2007-07-31 | Neurosearch A/S | 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| ATE519486T1 (de) * | 2003-10-16 | 2011-08-15 | Neurosearch As | Pharmazeutische zusammensetzung mit einem monoamin-neurotransmitter-wiederaufnahmehemmer und einem acetylcholinesterase-hemmer |
| CA2554617A1 (en) * | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an n-methyl-d-aspartate (nmda) receptors antagonist |
| WO2005070428A1 (en) * | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and a dopamine agonist |
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2005
- 2005-05-28 WO PCT/EP2005/005748 patent/WO2005117874A1/en not_active Ceased
- 2005-05-28 EP EP05754244A patent/EP1755602A1/en not_active Withdrawn
- 2005-05-28 JP JP2007513821A patent/JP2008501656A/ja not_active Abandoned
- 2005-06-03 US US11/144,481 patent/US20050277664A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019534295A (ja) * | 2016-11-08 | 2019-11-28 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | フェノキシトリアゾール |
| JP7132218B2 (ja) | 2016-11-08 | 2022-09-06 | エフ．ホフマン－ラ ロシュ アーゲー | フェノキシトリアゾール |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005117874A1 (en) | 2005-12-15 |
| EP1755602A1 (en) | 2007-02-28 |
| US20050277664A1 (en) | 2005-12-15 |
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