JP2008303487A - Skin pruritus reducing underwear - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide underwear capable of relieving and reducing pruritus through wearing. <P>SOLUTION: The skin pruritus reducing underwear is made of a fiber material which is dyed with a turmeric extracted solution. The turmeric extracted solution is a turmeric extract subjected to fermentation treatment. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an underwear for reducing skin pruritus, and more particularly, to an underwear that can reduce skin pruritus caused by skin diseases such as atopic dermatitis and allergic dermatitis.

  Itching is an important symptom in many skin diseases, and particularly in diseases such as atopic dermatitis, scratching behavior is induced by a severe itching sensation. For this reason, it is easy to fall into a vicious circle in which the inflammation of the skin worsens and the itch becomes worse, and there are cases in which it interferes with life such as sleep disorders. In addition, the skin barrier may be destroyed by scratching behavior, and secondary diseases such as infection may occur. Therefore, suppressing itching is extremely important in the treatment of skin diseases such as atopic dermatitis.

  Steroids are generally used as therapeutic agents for skin diseases such as atopic dermatitis, but steroids have problems of side effects such as skin atrophy and capillary vasodilation. Has been done. However, a safe and effective therapeutic agent has not yet been marketed.

  Therefore, there has been a demand for means that is highly safe and that can effectively relieve pruritus caused by atopic dermatitis.

  This invention is made | formed in view of the said situation, and makes it a subject to provide the underwear which can reduce the pruritus feeling of a skin disease patient by wearing.

  As a result of intensive studies to solve the above problems, the present inventors have found that it is possible to reduce itch caused by skin diseases by wearing an undergarment dyed with a turmeric extract, and have completed the present invention. .

  That is, the present invention is an underwear for reducing skin pruritus, comprising a fiber material dyed with a turmeric extract.

  By wearing the undergarment of the present invention, itching can effectively relieve pruritus associated with skin diseases such as atopic dermatitis. Therefore, the quality of life (QOL; Quality Of) of patients such as improvement of sleep can be safely achieved. Life) can be improved and deterioration of symptoms can be prevented.

  The underwear of this invention is comprised from the fiber material dye | stained with the turmeric extract.

  Turmeric (Curcuma Longa.L) used in the present invention is a perennial herb of the family Ginger, and both turmeric (autumn turmeric) and gypsophila (spring turmeric) can be used. The turmeric extract used in the present invention can be obtained by immersing the turmeric rhizome in an appropriate solvent and extracting the turmeric extract at 60 to 100 ° C. for about 20 to 60 minutes. Turmeric rhizomes may be used as they are, but may be sliced or pulverized to an appropriate size for extraction, or dried and pulverized into powder. Of these, powder is preferable because of its high extraction efficiency. As a solvent for extracting turmeric, water, a solvent such as ethanol, propylene glycol, or the like can be used. However, water may be used due to the possibility of skin irritation caused by the remaining solvent. The amount of turmeric used for extraction is usually 1 to 10 parts, preferably 2 to 6 parts, with respect to 100 parts by mass of solvent (hereinafter simply referred to as “parts”) in the case of powder. Further, the amount of turmeric with respect to 100 parts of the fabric to be dyed is usually 70 to 120 parts, preferably 90 to 120 parts in the case of powder.

  Moreover, since turmeric can further increase the effect of reducing pruritus by fermentation treatment, it is preferable to use turmeric that has been subjected to fermentation treatment. Turmeric fermentation treatment can be performed according to a known method, for example, a method described in JP-A-2004-345986 can be used. Moreover, since fermented turmeric powder (made by Ryukyu BioResource Co., Ltd.) is commercially available as fermented turmeric powder, it can also be used.

  The fiber material constituting the fiber material used in the present invention is not particularly limited, and examples thereof include natural fibers such as cotton, hemp, silk and wool, and synthetic fibers such as rayon, but are easily dyed with a turmeric extract. From the viewpoint of sheath skin irritation, natural fibers are preferable, and organically cultivated cotton (organic cotton) is particularly preferable. Examples of the form of the fiber material include yarns, woven fabrics, knitted fabrics, non-woven fabrics, felts, and the like manufactured by a conventional method using these fibers. In addition, this fabric includes those that have been sewn in the form of underwear.

  Although it does not specifically limit as a method of dyeing | staining the said fiber material with an above-described turmeric extract, A fiber material is 60-100 degreeC in about 10-40 mass times turmeric extract with respect to a fiber material. And may be immersed for about 8 to 15 hours. Further, as a pretreatment for dyeing, it is preferable to dye the fiber material after scouring it by a conventional method to remove impurities.

  In dyeing the fiber material, a mordanting treatment can be performed. The mordanting treatment may be either pre-morning performed before dyeing or post-mordanting performed after dyeing. Examples of the mordant used for the mordant treatment include a titanium mordant, an aluminum mordant, and an acid mordant. Examples of the titanium mordant include titanium sulfate and the like, examples of the aluminum mordant include alum, aluminum oxide, and aluminum chloride. Examples of the acid mordant include citric acid, ume vinegar, and glacial acetic acid. The amount of these mordants used varies depending on the type of mordant, but is usually 5 to 40 parts, preferably 10 to 30 parts, relative to 100 parts of the fabric. In the mordanting treatment, such an amount of mordant is dissolved in about 10 to 40 times the mass of the fiber material, and the fiber material is immersed in the fiber material at 34 to 50 ° C. for about 8 to 12 hours.

  The fiber material dyed with the turmeric extract is washed with water and dried as appropriate, and when the fiber material is a thread or an unsewn fabric, knitting, weaving, sewing, etc. are performed according to a conventional method to produce an underwear. The In this specification, the underwear means a textile product that comes into direct contact with the skin, and specifically includes T-shirts, underwear, gloves, socks, pajamas, sheets, mufflers, scarves, masks, etc. Among them, T-shirts, underwear, pajamas, and the like are preferable because they are highly effective in reducing pruritus. The fiber material dye | stained with the turmeric extract should just be used for all or one part of these underwear.

  Thus, the underwear of this invention obtained can reduce the pruritus feeling accompanying a skin disease by wearing.

  EXAMPLES Next, although an Example is given and this invention is demonstrated in more detail, this invention is not restrict | limited at all by these Examples.

Example 1
Production of turmeric dyed underwear:
1 kg of cotton fabric was scoured with an aqueous solution in which 200 g of Danshade-186 (manufactured by Nittobo Co., Ltd.) was dissolved in 25 L of water, and dried for 3 hours with sun drying. 150 g of alum was dissolved in 25 L of water, and the refined fabric was immersed in this aqueous solution at 36 ° C. for 24 hours to perform a mordant treatment, followed by drying for 3 hours by drying in the sun. 1 kg of fermented turmeric powder (trade name: fermented turmeric powder; manufactured by Ryukyu BioResource) was mixed with 25 L of water and extracted at 100 ° C. for 20 minutes to obtain a turmeric extract. The mordant-treated fabric was immersed in 25 L of this boiling turmeric extract. After heating and stirring for 30 minutes, the heating was stopped and the film was immersed for 8 hours. The fabric was then washed with water, dried for 15 minutes and then shaded. This was repeated twice to obtain a turmeric dyed fabric. This fabric was sewn to produce a T-shirt.

Example 2
Itching sensation reduction effect test:
The T-shirt obtained in Example 1 was worn for 23 months by 23 patients with atopic dermatitis having the symptom level and age structure shown in Table 1 below (daily wear time of 6 to 10). time). Then, it was asked to evaluate the effect of reducing pruritus according to the following question items and evaluation criteria, and the effect of reducing pruritus of the present underwear was examined. The results are shown in Table 2.

(Evaluation methods)
Question 1: How was the sleeping comfort of turmeric dyed clothing?
Score: Standard 3: Sleep better than before 2: Sleep better than before 1: Question 2 that does not change at all: Question 1 The effect of sleepiness of turmeric dyeing has been maintained for many days Or just below?
Score: Standard 3: More than 3 weeks 2: Less than 2-3 weeks 1: Less than 1-2 weeks Question 3: How was the itch of the affected area when wearing the turmeric dyed clothing of Question 1 compared to the past? ?
Score: Standard 3: Number of scratches decreased 2: Number of scratches decreased slightly 1: No change at all: Question 4: Skin condition of affected area due to wearing turmeric dyed clothes compared to the past How was it?
Score: Standard 3: Very good 2: A little better 1: No change

  From this result, it became clear that by wearing pajamas stained with turmeric extract, itching of atopic dermatitis is alleviated and sleep is improved.

  According to the present invention, itchyness associated with skin diseases such as atopic dermatitis and allergic dermatitis can be reduced, and sleep can be improved. Therefore, the underwear of this invention is useful in order to improve the quality of life (QOL) of a skin disease patient, and to suppress the deterioration of a symptom.

Claims (6)

  An underwear for reducing skin pruritus, comprising a fiber material dyed with a turmeric extract.   The underwear for reducing skin pruritus according to claim 1, wherein the turmeric extract is a fermented turmeric extract.   The underwear for reducing skin pruritus according to claim 1 or 2, wherein the fiber material constituting the fiber material is a fiber selected from the group consisting of cotton, hemp, silk, wool and rayon.   4. The underwear for reducing skin pruritus according to any one of claims 1 to 3, wherein the fiber material is mordanted.   The underwear for reducing skin pruritus according to claim 4, wherein the mordant used for the mordant treatment is selected from the group consisting of a titanium mordant, an aluminum mordant and an acid mordant.   The underwear for reducing skin pruritus according to any one of claims 1 to 5, wherein the skin pruritus is caused by atopic dermatitis.