JP2008154589A5 - - Google Patents
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- Publication number
- JP2008154589A5 JP2008154589A5 JP2008000091A JP2008000091A JP2008154589A5 JP 2008154589 A5 JP2008154589 A5 JP 2008154589A5 JP 2008000091 A JP2008000091 A JP 2008000091A JP 2008000091 A JP2008000091 A JP 2008000091A JP 2008154589 A5 JP2008154589 A5 JP 2008154589A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- pharmaceutical composition
- cancer
- nmb
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 16
- 206010028980 Neoplasm Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 4
- 230000002159 abnormal effect Effects 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 208000008839 Kidney Neoplasms Diseases 0.000 claims 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 206010038389 Renal cancer Diseases 0.000 claims 2
- 201000007455 central nervous system cancer Diseases 0.000 claims 2
- 201000010982 kidney cancer Diseases 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25426800P | 2000-12-08 | 2000-12-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002548191A Division JP2005516579A (ja) | 2000-12-08 | 2001-12-10 | 障害に関連する結節硬化複合症の検出法および処置法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008154589A JP2008154589A (ja) | 2008-07-10 |
| JP2008154589A5 true JP2008154589A5 (cg-RX-API-DMAC7.html) | 2009-05-07 |
Family
ID=22963608
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002548191A Pending JP2005516579A (ja) | 2000-12-08 | 2001-12-10 | 障害に関連する結節硬化複合症の検出法および処置法 |
| JP2008000091A Pending JP2008154589A (ja) | 2000-12-08 | 2008-01-04 | 結節性硬化症複合体関連障害の検出法および処置法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002548191A Pending JP2005516579A (ja) | 2000-12-08 | 2001-12-10 | 障害に関連する結節硬化複合症の検出法および処置法 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20030124534A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1385993B8 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2005516579A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE506075T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002226079A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2431861A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60144493D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK1385993T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2002046475A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030211488A1 (en) | 2002-05-07 | 2003-11-13 | Northwestern University | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection |
| CA2439440A1 (en) * | 2002-09-05 | 2004-03-05 | Emory University | Treatment of tuberous sclerosis associated neoplasms |
| EP1522857A1 (en) * | 2003-10-09 | 2005-04-13 | Universiteit Maastricht | Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2 |
| NZ549040A (en) | 2004-02-17 | 2009-07-31 | Schering Corp | Use for interleukin-33 (IL33) and the IL-33 receptor complex |
| DK1827492T3 (da) | 2004-11-30 | 2010-11-22 | Curagen Corp | Antistoffer rettet mod GPNMB og anvendelser deraf |
| US20120252877A1 (en) * | 2009-08-14 | 2012-10-04 | Theramind Research, Llc | Methods and compositions for treatment of tuberous sclerosis complex |
| US9925202B2 (en) | 2013-03-04 | 2018-03-27 | Brigham And Women's Hospital, Inc. | Treatment of lymphangioleiomyomatosis |
| US20160129030A1 (en) * | 2013-06-14 | 2016-05-12 | The Brigham And Women's Hospital, Inc. | Treatment of mtor hyperactive related diseases and disorders |
| WO2023178250A1 (en) * | 2022-03-17 | 2023-09-21 | SpringWorks Therapeutics Inc. | Treatment of tuberous sclerosis with mirdametinib |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US5225539A (en) * | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| JP2874751B2 (ja) | 1986-04-09 | 1999-03-24 | ジェンザイム・コーポレーション | 希望する蛋白質をミルク中へ分泌する遺伝子移植動物 |
| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| JP3715314B2 (ja) * | 1993-12-24 | 2005-11-09 | ユニバーシティ オブ ウェールズ カレッジ オブ メディスン | 結節硬化症２遺伝子及びその利用 |
| US5871697A (en) * | 1995-10-24 | 1999-02-16 | Curagen Corporation | Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing |
| WO1997018454A2 (en) * | 1995-11-16 | 1997-05-22 | Baylor College Of Medicine | Method for identifying metastatic sequences |
| US20020147143A1 (en) | 1998-03-18 | 2002-10-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| EP2028190A1 (en) | 1999-04-02 | 2009-02-25 | Corixa Corporation | Compounds and methods for therapy and diagnosis of lung cancer |
| US6620615B1 (en) * | 1999-04-23 | 2003-09-16 | Curagen Corporation | G-protein coupled receptor—encoding nucleic acids |
| AU2001273150A1 (en) | 2000-07-20 | 2002-02-05 | Genentech Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| WO2002062947A2 (en) | 2000-10-20 | 2002-08-15 | University Of Medicine And Dentistry New Jersey Medical School | Hematopoietic growth factor inducible neurokinin-1 gene |
| AU2002304814A1 (en) | 2001-03-14 | 2002-11-05 | Hybrigenics | Protein-protein interactions in adipocytes |
| AU2002309583A1 (en) | 2001-04-18 | 2002-11-05 | Protein Desing Labs, Inc. | Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer |
-
2001
- 2001-12-10 AU AU2002226079A patent/AU2002226079A1/en not_active Abandoned
- 2001-12-10 DK DK01995497.3T patent/DK1385993T3/da active
- 2001-12-10 AT AT01995497T patent/ATE506075T1/de not_active IP Right Cessation
- 2001-12-10 EP EP01995497A patent/EP1385993B8/en not_active Expired - Lifetime
- 2001-12-10 CA CA002431861A patent/CA2431861A1/en not_active Abandoned
- 2001-12-10 WO PCT/US2001/047839 patent/WO2002046475A2/en not_active Ceased
- 2001-12-10 DE DE60144493T patent/DE60144493D1/de not_active Expired - Lifetime
- 2001-12-10 US US10/016,253 patent/US20030124534A1/en not_active Abandoned
- 2001-12-10 JP JP2002548191A patent/JP2005516579A/ja active Pending
-
2004
- 2004-11-16 US US10/991,173 patent/US20050181391A1/en not_active Abandoned
-
2008
- 2008-01-04 JP JP2008000091A patent/JP2008154589A/ja active Pending
- 2008-04-02 US US12/080,362 patent/US20080292624A1/en not_active Abandoned
-
2012
- 2012-05-02 US US13/462,300 patent/US9051615B2/en not_active Expired - Fee Related
-
2015
- 2015-05-07 US US14/706,105 patent/US20150232948A1/en not_active Abandoned
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