JP2008094756A - Powder cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a means for enhancing the absorption of an active ingredient in a powder cosmetic. <P>SOLUTION: The powder cosmetic contains (1) a covered powder covered with a water-soluble covering agent, and (2) the active ingredient. The active ingredient is one or more kinds selected from the following group B in the water-soluble polymer-covered powder: (B) glycyrrhizic acid, lysozyme, ascorbic acid, ascorbic acid phosphate, ascorbic acid glucoside, kojic acid, arbutin, 4-alkylresorcinol, tranexamic acid, tranexamic acid methyl amide and salts of the components. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to cosmetics, and more particularly to powder cosmetics.

  In powder cosmetics defined as cosmetics containing 60% by mass or more, more preferably 75% by mass or more of powders, active ingredients such as ordinary liquid cosmetics and emulsified cosmetics are dissolved. Compared with cosmetics that come into contact with the skin, the absorption of active ingredients to the skin is considered to be low, so there are few cases that contain active ingredients in anticipation of action on the skin, and the cosmetics themselves It can be said that most cases contain it to ensure stability. This is because in powder cosmetics, the contact between the active ingredient and the skin is in most cases a solid-solid contact, and the contact area is also obstructed by the presence of an overwhelming number of powders. It seems to be because. However, if the powder cosmetic is located in the outermost shell of the cosmetic film and can be used to promote percutaneous absorption of the active ingredient, it can be said to be a very preferable technique. This is because it also gives a new function to makeup cosmetics. The knowledge about the relationship between the powder and the percutaneous absorption promoting action is that the cosmetic film has a specific nuclear magnetic resonance relaxation time, and the powdered aqueous carrier dispersion cosmetic is applied on the active ingredient. The content is to promote the percutaneous absorption of the active ingredient. However, the relaxation time is case by case, and it is difficult to say that this technique is practical. (For example, see Patent Document 1)

  On the other hand, in powder cosmetics, a technique is already known in which the surface is coated with a water-soluble polymer in advance to modify the surface characteristics of the powder, for example, to suppress caking. (For example, see Patent Document 2, Patent Document 3, Patent Document 4, and Patent Document 5) However, it is quite known that such a coated powder has an action of promoting absorption of an active ingredient contained in cosmetics. It is not done.

Japanese Patent Laid-Open No. 2002-30001 JP 09-25217 A JP-A-2005-194212 JP 2002-201113 A JP 2004-137199 A

  The present invention has been made under such circumstances, and an object of the present invention is to provide means for enhancing absorption of active ingredients in powder cosmetics.

In view of such a situation, the present inventors have sought for means for enhancing the absorption of active ingredients in powder cosmetics, and as a result of intensive research efforts, they are coated with a water-soluble coating agent. It has been found that when the powder cosmetic is applied to the skin by containing the coated powder in the powder cosmetic, it has an action of promoting percutaneous absorption of the active ingredient in the powder cosmetic. It came to complete. That is, the present invention is as follows.
(1) A powder cosmetic comprising 1) a coated powder coated with a water-soluble coating agent, and 2) an active ingredient.
(2) In the water-soluble polymer-coated powder, the water-soluble coating agent used for coating is one or more selected from the following group A, and the active ingredient is group B The powder cosmetic according to (1), wherein the powder cosmetic is one or more selected from the group consisting of:
(A) Glucosyloxyethyl (meth) acrylic acid polymer or copolymer, polymethacryloyl-L-lysine, (meth) acryloyloxyethyl phosphorylcholine polymer or copolymer, sulfated trehalose, seaweed extract, seed mucilage, liquid Mucilage, fruit mucilage, cereal protein, animal peptide, mucopolysaccharide, cellulose-based water-soluble polymer, starch-based water-soluble polymer, microbial-produced viscous material, guar gum-based water-soluble polymer, alkyl-modified Good carboxyvinyl polymer, poly (meth) acrylamide, poly (meth) acrylic acid, polyethyleneimine, highly polymerized polyethylene glycol, polyvinyl alcohol, polyvinylpyrrolidone, salt of the above components (B) glycyrrhizic acid, lysozyme, ascorbic acid, phosphorus ascorbate acid Steal, ascorbic acid glucoside, kojic acid, arbutin, 4-alkylresorcinol, tranexamic acid, tranexamic acid methylamide, salt of the component (3) The water-soluble coating agent is hyaluronic acid and / or a salt thereof The powder cosmetic according to (1) or (2).
(4) The powder cosmetic according to any one of (1) to (3), wherein the active ingredient is glycyrrhizic acid and / or a salt thereof.
(5) The powder used as the base of the coated powder is selected from sericite, titanium sericite which may be coated with other metal oxides, and titanium mica. The powder cosmetic according to any one of 1) to (4).
(6) The powder cosmetic according to any one of (1) to (5), wherein the powder cosmetic is defined as a cosmetic containing 60% by mass or more of powder.

  ADVANTAGE OF THE INVENTION According to this invention, the means which raises absorption of an active ingredient can be provided in powder cosmetics.

(1) Coated powder which is an essential component of the powder cosmetic of the present invention The powder cosmetic of the present invention contains a coated powder coated with a water-soluble coating agent as an essential component. In the water-soluble polymer-coated powder, the water-soluble coating agent used for coating is preferably one or more selected from the following group A. Preferred among such Group A components are polymers or copolymers of glucosyloxyethyl (meth) acrylic acid, polymers or copolymers of polymethacryloyl-L-lysine, (meth) acryloyloxyethyl phosphorylcholine, sulfated trehalose, Hyaluronic acid and a salt thereof are selected, and hyaluronic acid and / or a salt thereof is particularly preferable.

(A) Polymers or copolymers of glucosyloxyethyl (meth) acrylic acid, polymers or copolymers of polymethacryloyl-L-lysine, (meth) acryloyloxyethyl phosphorylcholine, sulfated trehalose, alginic acid, carrageenan, agar, fercelane, etc. Seaweed extract, guar gum, quince seed, konjac mannan, tamarind gum, tara gum, dextrin, starch, locust bean gum, etc. Fruit mucilage such as quince, grain protein such as wheat protein and soy protein, animal peptide such as albumin, casein and gelatin, mucopolysaccharide such as chitosan and hyaluronic acid, microcrystalline cellulosic Cellulose-based water-soluble polymers such as cellulose, methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, carboxymethylcellulose, and cationized cellulose, and starch-based water-soluble polymers such as starch phosphate ester and sodium starch glycolate , Curdlan, xanthan gum, duran gum, cyclodextrin, dextran, pullulan, etc. Carboxyvinyl polymer, poly (meth) acrylamide, poly (meth) acrylic acid, polyethyleneimine, high polymerization Triethylene glycol, polyvinyl alcohol, polyvinyl pyrrolidone, salts of the components

  In the coated powder that is an essential component of the cosmetic of the present invention, when the powder is coated using the component of the group A to produce a coated powder, the component of the group A is the surface of the powder. It is preferable to coat the film so that it is evenly distributed. For this purpose, an aqueous carrier solution of the components of group A is prepared, and the powder is immersed in the solution, and then the aqueous carrier is volatilized and coated. Is preferred. As the aqueous carrier solution, an aqueous solution of 0.1 to 10% by mass is preferable. Of course, after mixing, a mechanochemical treatment can be applied with a pulverizer or the like, and then mixed coating is possible, but coating by an aqueous solution dipping method is preferable in terms of effect. This is because it is suitable for obtaining the uniformity of the coating. The base powder to be subjected to such coating treatment is not particularly limited as long as it is used as a cosmetic raw material. For example, talc, kaolin, sericite, mica, titanium mica, titanium sericite , Firing such as silica, alumina, calcium silicate, magnesium silicate, calcium carbonate, magnesium carbonate, titanium dioxide, zinc oxide, bengara, yellow iron oxide, black iron oxide, etc., ultramarine, bitumen or a combination of these The composite powder etc. which were combined and can be illustrated suitably. In such a coating, a preferred mass ratio of the component A to the powder is 1: 999 to 30:70, more preferably 2: 998 to 20:80. Below, the manufacture example of preferable coating powder is shown.

<Production Example 1> Production of Coated Powder 1 (Sodium Hyaluronate) Coated Powder To 500 g of 0.2% aqueous solution of sodium hyaluronate (manufactured by Kibun Food Chemifa), sericite and stearic acid coated with titanium oxide / Bengara sinter 199 g of zinc (manufactured by Miyoshi Kasei) was dispersed, poured into a tray thinly, dried at 40 ° C. for 3 days, and then pulverized with a pulverizer to prepare a coated powder 1.

<Production Example 2> Production of coated powder 2 (sodium hyaluronate) mixed coated powder 1 g of sodium hyaluronate (manufactured by Kibun Food Chemifa) and titanium oxide / Bengara sinter coated sericite / zinc stearate (manufactured by Miyoshi Kasei) 199 g was mixed with a mixer and pulverized with a pulverizer to prepare a coated powder 2.

<Production Example 3> Production of coated powder 3 (polyglucosyloxyethyl methacrylate coated powder) To 500 g of 0.2% aqueous solution of polyglucosyloxyethyl methacrylate (manufactured by Nippon Seika), anhydrous silicic acid / Bengala coated titanium sericite (Catalyst Chemical Co., Ltd.) 199 g was dispersed, poured into a tray thinly, dried at 40 ° C. for 3 days, and then pulverized with a pulverizer to prepare a coated powder 3.

<Production Example 4> Production of coated powder 4 (polyglucosyloxyethyl methacrylate mixed coated powder) 1 g of polyglucosyloxyethyl methacrylate (manufactured by Nippon Seika Co., Ltd.) and silicic acid / Bengala coated titanium sericite (manufactured by Catalytic Chemical) ) 199 g was mixed with a mixer and pulverized with a pulverizer to prepare a mixed coated powder 4.

<Manufacture example 5> Manufacture of sulfated trehalose-coated powder Disperse 199 g of sericite (manufactured by Sanshin Mining Co., Ltd.) in 500 g of 0.2% aqueous solution of sulfated trehalose (manufactured by Nippon Shokuhin Kako). After drying at 0 ° C. for 3 days, the coated powder 5 was prepared by pulverization with a pulverizer.

<Production Example 6> Production of sulfated trehalose mixed powder 1 g of sulfated trehalose (manufactured by Nippon Shokuhin Kako)) and 199 g of sericite (manufactured by Sanshin Mining) are mixed with a mixer, pulverized with a pulverizer, and mixed coated powder 6 It was created.

<Production Example 7> Production of Carboxyvinyl Polymer Coated Powder 199 g of mica titanium (manufactured by Teika) is dispersed in 500 g of a 0.2% aqueous solution of carboxyvinyl polymer (manufactured by BFGoodrich) and poured into a tray thinly at 40 ° C. for 3 days. After drying, it was pulverized with a pulverizer to prepare a coated powder 7.

<Production Example 8> Production of carboxyvinyl polymer mixed powder 1 g of carboxyvinyl polymer (manufactured by BFGoodrich)) and 199 g of mica titanium (manufactured by Teika) were mixed with a mixer and pulverized with a pulverizer to prepare a mixed coated powder 8.

(2) The active ingredient which is an essential component of the cosmetics of this invention The cosmetics of this invention contain an active ingredient as an essential component, It is characterized by the above-mentioned. The active ingredient referred to in the present invention means an ingredient that is contained in anticipation of a favorable physiological action on the skin. Specifically, the anti-inflammatory action, the whitening action, the anti-wrinkle action, the rough skin improving action, the anti-combination effect It is a component having an action such as action. Such components are more preferably water-soluble. Examples of such components include glycyrrhizic acid, lysozyme, ascorbic acid, ascorbic acid phosphate ester, ascorbic acid glucoside, kojic acid, arbutin, 4-hexylresorcinol, 4-cyclohexylresorcinol, 4-cyclopentylresorcinol, Preferable examples include 4-alkylresorcinols such as 4- (1-methylpropyl) resorcinol and 4- (1-methylbutyl) resorcinol, tranexamic acid, tranexamic acid methylamide, tacrolimus, and salts of the above components. The suitable content of such components is 0.1 to 5% by mass, more preferably 0.2 to 3% by mass. Such a component can contain only one species, or a combination of two or more species. The percutaneous absorbability can be enhanced by incorporating it in the solid powder cosmetic in the presence of the coating powder.

(3) Cosmetics of this invention The cosmetics of this invention are powder cosmetics, Comprising: The said coating powder and the said active ingredient are contained as an essential component, It is characterized by the above-mentioned. In the present invention, the powder cosmetic is a cosmetic containing 60% by mass or more, more preferably 75% by mass or more of powder, and usually takes the form of pressed powder or loose powder. The powder cosmetic of the present invention is preferably a solid powder cosmetic, and particularly preferably takes the form of a solid powder cosmetic that is pressure-molded in a metal pan.

  In the cosmetic of the present invention, in addition to the essential components, any component used in the powder-containing cosmetic can be contained. Such optional ingredients include, for example, macadamia nut oil, avocado oil, corn oil, olive oil, rapeseed oil, sesame oil, castor oil, safflower oil, cottonseed oil, jojoba oil, coconut oil, palm oil, liquid lanolin, hydrogenated coconut oil Oil, wax, oils such as beeswax, owl, hardened castor oil, beeswax, candelilla wax, carnauba wax, botarou, lanolin, reduced lanolin, hard lanolin, jojoba wax , Hydrocarbons such as microcrystalline wax; higher fatty acids such as oleic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, undecylenic acid; cetyl alcohol, stearyl alcohol, isostearyl Higher alcohols such as alcohol, behenyl alcohol, octyldodecanol, myristyl alcohol, cetostearyl alcohol; cetyl isooctanoate, isopropyl myristate, hexyldecyl isostearate, diisopropyl adipate, di-2-ethylhexyl sebacate, cetyl lactate, malic acid Diisostearyl, di-2-ethylhexanoic acid ethylene glycol, dicaprate neopentyl glycol, di-2-heptylundecanoic acid glycerin, tri-2-ethylhexanoic acid glycerin, tri-2-ethylhexanoic acid trimethylolpropane, tri Synthetic ester oils such as trimethylolpropane isostearate and pentane erythritol tetra-2-ethylhexanoate; dimethylpolysiloxane, methylphenylpoly Linear polysiloxanes such as oxane and diphenylpolysiloxane; cyclic polysiloxanes such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexanesiloxane; amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, Oil agents such as silicone oils such as modified polysiloxanes such as fluorine-modified polysiloxanes; Anionic surfactants such as fatty acid soap (sodium laurate, sodium palmitate, etc.), potassium lauryl sulfate, triethanolamine ether of alkyl sulfates; Cationic surfactants such as stearyltrimethylammonium, benzalkonium chloride, laurylamine oxide; imidazoline-based amphoteric surfactants (2-cocoyl-2-imida Zolinium hydroxide-1-carboxyethyloxy disodium salt, etc.), betaine surfactants (alkyl betaine, amide betaine, sulfobetaine, etc.), and amphoteric surfactants such as acylmethyltaurine; sorbitan fatty acid esters (sorbitan) Monostearate, sorbitan sesquioleate, etc.), glycerin fatty acids (eg, glyceryl monostearate), propylene glycol fatty acid esters (eg, propylene glycol monostearate), hardened castor oil derivatives, glycerin alkyl ethers, POE sorbitan fatty acid esters (POE sorbitan monooleate, polyoxyethylene sorbitan monostearate, etc.), POE sorbite fatty acid esters (POE-sorbitol monolaurate, etc.), POE glycerin fatty acid ester Tells (POE-glycerol monoisostearate, etc.), POE fatty acid esters (polyethylene glycol monooleate, POE distearate, etc.), POE alkyl ethers (POE2-octyldodecyl ether, etc.), POE alkylphenyl ethers (POE nonylphenyl) Ethers, etc.), Pluronic types, POE / POP alkyl ethers (POE / POP2-decyltetradecyl ether, etc.), Tetronics, POE castor oil / hardened castor oil derivatives (POE castor oil, POE hardened castor oil, etc.), Nonionic surfactants such as sucrose fatty acid ester and alkyl glucoside; polyethylene glycol, glycerin, 1,3-butylene glycol, erythritol, sorbitol, xylitol, maltitol, propylene Polyhydric alcohols such as recall, dipropylene glycol, diglycerin, isoprene glycol, 1,2-pentanediol, 2,4-hexanediol, 1,2-hexanediol, 1,2-octanediol; sodium pyrrolidonecarboxylate Moisturizing ingredients such as lactic acid and sodium lactate; surface may be treated with a surface treating agent other than water-soluble coating agent, mica, talc, kaolin, synthetic mica, calcium carbonate, magnesium carbonate, silicic anhydride (silica) ), Powders such as aluminum oxide and barium sulfate; inorganic pigments such as bengara, yellow iron oxide, black iron oxide, cobalt oxide, ultramarine, bitumen, titanium oxide, and zinc oxide, the surface of which may be treated; Pearling agents such as titanium mica, fish phosphorus foil, bismuth oxychloride, etc. whose surface may be treated; Red 202, Red 228, Red 226, Yellow 4, Blue 404, Yellow 5, Red 505, Red 230, Red 223, Orange 201, Red 213, Yellow Organic dyes such as No. 204, Yellow No. 203, Blue No. 1, Green No. 201, Purple No. 201, Red No. 204; Organic powders such as polyethylene powder, polymethyl methacrylate, nylon powder, organopolysiloxane elastomer; Paraaminobenzoic acid UV absorbers; Anthranilic acid UV absorbers; Salicylic acid UV absorbers; Cinnamic acid UV absorbers; Benzophenone UV absorbers; Sugar UV absorbers; 2- (2'-hydroxy- UV absorbers such as 5′-t-octylphenyl) benzotriazole, 4-methoxy-4′-t-butyldibenzoylmethane; Lower alcohols such as alcohol and isopropanol; vitamin B such as vitamin A or its derivative, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 or its derivative, vitamin B12, vitamin B15 or its derivative Α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E such as vitamin E acetate, vitamin D, vitamin H, pantothenic acid, pantethine, vitamins such as pyrroloquinoline quinone, etc .; antibacterial agents such as phenoxyethanol Preferred examples can be given. The cosmetic of the present invention can be produced by treating these essential components and optional components according to a conventional method.

  The powder cosmetic of the present invention can be applied to powder cosmetics for various purposes by appropriately changing the composition of these raw materials. As the types of the cosmetics of the present invention, any powder cosmetics whose application is already known can be applied without particular limitation. For example, foundations, foundation powders, finish powders, cheek colors, eye colors Suitable examples include UV protective cosmetics, water-use cakes, amphibious cakes, body powders, and the like.

  The cosmetics of the present invention will be described in more detail below with reference to examples, but it goes without saying that the cosmetics of the present invention are not limited to such examples.

  In order to confirm the effect of the present invention, dipotassium glycyrrhizinate was selected as an active ingredient, and this was mixed with the powders of Production Examples 1 to 8 and the powders of the respective substrates so as to be 2% by mass with a mixer. The permeability of the water-soluble active ingredient through the model membrane was evaluated. That is, a membrane filter (manufactured by MILLIPORE, 0.45 μm HA) was set in a Franz diffusion cell (inner diameter 22 mm) and filled with an aqueous solution of PBS (manufactured by Dainippon Pharmaceutical). A 0.1 g dipotassium glycyrrhizinate mixed sample was spread uniformly on the filter, and the receptor solution was sampled after 32 hours at 32 ° C. For detection of dipotassium glycyrrhizinate, HPLC (Waters Alliance PDA system) was used. The amount in the receptor solution relative to the amount of dipotassium glycyrrhizinate in the mixed sample was defined as the transmittance. The results are shown in Table 1. This shows that the cosmetic of the present invention is excellent in the absorption promoting action of dipotassium glycyrrhizinate. Further, it can be seen that the powder coating treatment is preferably a coating treatment in which a solution is immersed and dried and coated, rather than a mixing / mechanochemical treatment.

  In the same manner as in Example 1, coating powder 1, mixed coating powder 2 and titanium oxide / Bengara sinter coated sericite / zinc stearate are selected as powders, and ascorbic acid is selected as an active ingredient for evaluation. As a result, the coated powder 1 was 55%, the mixed coated powder 2 was 24%, and the titanium oxide / Bengara sintered material-coated sericite / zinc stearate was 6%, and the same effect was recognized.

  In the same manner as in Example 1, coated powder 1, mixed coated powder 2 and titanium oxide / Bengara sinter coated sericite / zinc stearate were selected as powders, and arbutin was selected and evaluated as an active ingredient. However, the coated powder 1 was 62%, the mixed coated powder 2 was 37%, and the titanium oxide / Bengara sintered material-coated sericite / zinc stearate was 6%, and the same effect was recognized.

  As in Example 1, as powder, coated powder 1, mixed coated powder 2 and titanium oxide / Bengara sinter coated sericite / zinc stearate are selected, and 4-cyclohexylresorcinol is selected as the active ingredient As a result, the coated powder 1 was 70%, the mixed coated powder 2 was 37%, and the titanium oxide / Bengara sinter coated sericite / zinc stearate was 12%, and the same effect was recognized. .

  According to the prescription shown below, the powder cosmetics which are the cosmetics of this invention were manufactured. In other words, the component a is mixed with a Henschel mixer, pulverized with a pulverizer equipped with a 0.9 mm round hole screen, and the component B is sprayed while mixing with a Henschel mixer, and this is equipped with a 1 mm herringbone screen. The pulverizer was pulverized, filled into a metal pan, and pressure-molded to obtain a foundation. This had a skin care effect.

  The present invention can be applied to powder cosmetics.

Claims (6)

1. A powder cosmetic comprising 1) a coated powder coated with a water-soluble coating agent, and 2) an active ingredient. In the water-soluble polymer-coated powder, the water-soluble coating agent used for coating is one or more selected from the following group A, and the active ingredient is selected from the group B. The powder cosmetic according to claim 1, wherein the powder cosmetic is one or more kinds.
(A) Glucosyloxyethyl (meth) acrylic acid polymer or copolymer, polymethacryloyl-L-lysine, (meth) acryloyloxyethyl phosphorylcholine polymer or copolymer, sulfated trehalose, seaweed extract, seed mucilage, liquid Mucilage, fruit mucilage, cereal protein, animal peptide, mucopolysaccharide, cellulose-based water-soluble polymer, starch-based water-soluble polymer, microbial-produced viscous material, guar gum-based water-soluble polymer, alkyl-modified Good carboxyvinyl polymer, poly (meth) acrylamide, poly (meth) acrylic acid, polyethyleneimine, highly polymerized polyethylene glycol, polyvinyl alcohol, polyvinylpyrrolidone, salt of the above components (B) glycyrrhizic acid, lysozyme, ascorbic acid, phosphorus ascorbate acid Ester, ascorbic acid glucoside, kojic acid, arbutin, 4-alkyl resorcinol, tranexamic acid, methylamide tranexamic acid, salts of the components The powder cosmetic according to claim 1 or 2, wherein the water-soluble coating agent is hyaluronic acid and / or a salt thereof. The powder cosmetic according to any one of claims 1 to 3, wherein the active ingredient is glycyrrhizic acid and / or a salt thereof. The powder as a base of the coated powder is selected from sericite, titanium sericite which may be coated with other metal oxides, and titanium mica. 4. The powder cosmetic according to any one of 4 above. The powder cosmetic according to any one of claims 1 to 5, wherein the powder cosmetic is defined as a cosmetic containing 60% by mass or more of powder.