JP2008075221A - Skin-protecting finishing agent for washing, and method for imparting skin-protection property by using the agent - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a skin-protecting finishing agent capable of sufficiently imparting a textile product with skin-protecting properties such as chapping prevention and stimulation prevention effects without deteriorating the quality of the textile product in the washing of the textile product and provide a method for imparting skin-protecting property. <P>SOLUTION: The skin-protecting finishing agent for washing contains a coated ellagic acid particle produced by coating the surface of an ellagic acid particle with a hydrolyzed protein. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a skin protective finish for laundry and a method for imparting skin protection using the same. More specifically, the present invention is a skin protective finish for washing that can be added to the rinsing stage when washing textiles such as clothing and underwear to impart skin protection such as rough skin prevention and skin irritation prevention to the textile material. The present invention relates to an agent and a method for imparting skin protection using the agent.

  Textile products such as clothes and underwear become rough and hard when worn or washed. For this reason, laundry finishes are used in general households for the purpose of imparting flexibility and antistatic properties. Conventionally, many of the laundry finishes have used tertiary or quaternary ammonium salt type cationic surfactants such as dialkyldimethylammonium chloride and imidazoline. For example, Patent Document 1 listed below discloses the use of dialiphatic dimethylammonium chloride or dialiphatic alkylimidazolium methosulfate as a softener component.

  In recent years, with increasing interest in sanitary functional processing, development of functional finishes with functions such as antibacterial, deodorant, and skin care has been actively promoted. For example, the following Patent Document 2 discloses a stagnation-free laundry finish in which porous particles are impregnated with an extract from mugwort and cypress in order to impart stagnation-preventing properties. In order to impart an antibacterial function, a laundry finish containing animal bone powder is described in Patent Document 4 below, and an antibacterial finish that adds ε-polylysine and grapefruit seed extract to a rinsing bath to impart an antibacterial function is described below. Patent Document 5 discloses a deodorant antibacterial finish for laundry containing a plant extract extracted from a group of plants such as aloe and perilla to impart deodorant antibacterial properties.

  By the way, it is known that many cationic surfactants blended as a softener component induce skin disorders such as skin irritation, dermatitis, skin sensitization, allergic reaction, and rough skin. The cationic surfactant can be used as a softener component in the functional finishes of Patent Documents 2 to 5 as well as the fiber softener as described in Patent Document 1 described above. -5 does not describe a method for preventing the occurrence of the above skin disorders. Therefore, the addition of a function capable of sufficiently suppressing skin damage is required for the laundry finish.

  Techniques for preventing the occurrence of skin damage caused by surfactants have been studied so far. For example, Patent Document 6 listed below includes gallic acid and its derivatives, tannic acid, and ellagic acid and its derivatives. A rough skin-preventing fiber material has been proposed in which one or more of these are fixed to a fiber material.

JP 58-109682 A JP-A-8-49172 Japanese Patent Laid-Open No. 9-59877 JP-A-11-61639 JP 2002-212877 A JP 2002-293737 A

  However, according to the study by the present inventors, the component described in Patent Document 6 can suppress skin damage caused by a cationic surfactant such as benzalkonium chloride and is useful for preventing rough skin. If the composition is applied to a fiber, it may cause problems such as coloring of the fiber due to the influence of the pH of the fabric, the metal content of the fabric, etc. It has been found that it may be difficult to obtain the effect of suppressing the above.

  As a method for protecting the active ingredient from the external environment, the use of microcapsules can be considered, but in order to effectively release the core substance and to effectively express the function of the core substance, the wall material is appropriately selected. There is a need. For example, Japanese Patent Application Laid-Open No. 2004-113975 discloses a technique using a polymer of a monomer mixture containing a monomer having a phosphorylcholine-like group as a wall material of a microcapsule encapsulating a physiologically active substance such as ellagic acid. Has been. However, the above method has a problem that the process of microencapsulation is complicated and the texture of the fiber product to which the microcapsules enclosing the physiologically active substance are fixed becomes hard, and is applied as a finishing agent for washing. Is not necessarily enough.

  The present invention has been made in view of the above-mentioned problems of the prior art. When washing a textile product, the textile product provides skin protection such as prevention of rough skin and prevention of skin irritation without impairing the quality of the textile product. An object of the present invention is to provide a skin protective finish for washing and a method for imparting skin protection, which can be sufficiently applied to the skin.

  As a result of intensive studies to solve the above-mentioned object, the present inventors have added a finishing agent for washing containing coated ellagic acid particles in which the surface of ellagic acid particles is coated with hydrolyzed protein in the washing rinse stage. As a result, the textile product after washing has high hyaluronidase activity inhibitory property, and even when used in combination with a cationic surfactant, it is sufficiently low in skin irritation and sufficiently reduces discoloration of the fiber. As a result, the present invention has been completed.

  That is, the skin protective finish for laundry of the present invention contains coated ellagic acid particles formed by coating the surface of ellagic acid particles with a hydrolyzed protein.

  According to the skin protective finish for washing of the present invention, by containing the coated ellagic acid particles, discoloration of the textile product after washing can be sufficiently reduced, and the rough skin is prevented without impairing the quality of the product. Skin protection such as prevention of skin irritation and skin can be sufficiently imparted to textile products. Such effects can be easily and sufficiently obtained even in a general household washing machine by adding the skin protective finish for washing of the present invention to the rinsing water in the washing rinsing stage.

  In the skin protective finish for laundry of the present invention, the hydrolyzed protein preferably has a weight average molecular weight of 8,000 to 800,000. In this case, the surface of the ellagic acid particles is satisfactorily coated, and the color of the textile after washing can be reduced, and sufficient skin protection can be more reliably obtained.

  The skin protective finish for laundry of the present invention preferably further comprises a soft component. In this case, the action of alleviating the chemical stimulus of the soft component by the coated ellagic acid and the action of reducing the physical stimulus by the soft component can be combined to alleviate the stimulating action of the textile product. Skin irritation can be achieved.

  Further, the present invention is a method for imparting skin protection to a textile product when the textile product is washed, and the textile product is rinsed with rinsing water containing the laundry skin protective finish of the present invention. There is provided a method for imparting skin protection, comprising a step.

  According to the method for imparting skin protection of the present invention, discoloration of a textile product after washing can be sufficiently reduced, and skin protection such as prevention of rough skin and prevention of skin irritation can be applied to the textile product without impairing the quality of the product. It can be given enough.

  According to the present invention, it is possible to sufficiently reduce discoloration of a textile product after washing, and to impart sufficient skin protection such as rough skin prevention and skin irritation prevention to the textile product without impairing the quality of the product. It is possible to provide a skin protective finish for laundry and a method for imparting skin protection.

  Hereinafter, the skin protective finish for washing of the present invention and the method for imparting skin protection using the same will be described in detail according to preferred embodiments thereof.

  The skin protective finish for laundry of the present invention comprises coated ellagic acid particles formed by coating the surface of ellagic acid particles with hydrolyzed protein.

  The ellagic acid particles used in the present invention may be synthesized by a conventional method, or a commercially available product may be obtained. The average particle size of the ellagic acid particles is preferably from 0.1 to 100 μm, more preferably from 0.2 to 10 μm.

  Examples of the hydrolyzed protein used in the present invention include hydrolyzed keratin, hydrolyzed collagen, hydrolyzed casein, hydrolyzed yeast protein, hydrolyzed wheat, hydrolyzed conchiolin, hydrolyzed silk, hydrolyzed vegetable protein, and soy protein hydrolyzed. Products, and their esterified products and acetylated products. The hydrolyzed protein usually contains a small amount of a product degraded to the amino acid level. In the present invention, such hydrolyzed protein can also be used.

  The hydrolyzed protein used in the present invention preferably has a weight average molecular weight of 8,000 to 800,000, more preferably 30,000 to 700,000, and 80,000 to 600,000. Is particularly preferred. Here, the weight average molecular weight means a molecular weight determined by gel filtration chromatography using a protein having a known molecular weight as a measurement standard substance. That is, the hydrolyzed protein used in the present invention has a weight average molecular weight of 0.05 M phosphate buffer containing Superdex 200HR 10/30 (manufactured by GE Healthcare Biosciences) as a column and 0.15 M NaCl as an eluent. The gel filtration chromatography “HLC-8120GPC system” (manufactured by Tosoh Corporation) using pH 7.0 was measured under conditions of a flow rate of 0.25 mL / min and a temperature of 25 ° C., and Gel Filtration Calibration Kit LMW And Gel Filtration Calibration Kit HMW (manufactured by GE Healthcare Bioscience Co., Ltd.). When the weight average molecular weight of the hydrolyzed protein is within the above range, it becomes easy to form a coating layer that sufficiently covers the surface of the ellagic acid particles, and it is possible to reduce coloration on the textile after washing, Safe skin protection can be obtained more reliably.

  The method for producing the coated ellagic acid particles contained in the laundry skin protective finish of the present invention is not particularly limited. For example, the coated ellagic acid particles can be obtained by the following method. First, ellagic acid particles, an aqueous solution of the above hydrolyzed protein, and a dispersant as necessary are mixed, and then a pH adjuster is added to the mixture to add water below the isoelectric point of the hydrolyzed protein. By insolubilizing the degraded protein, coated ellagic acid particles in which the surface of the ellagic acid particles is coated with the hydrolyzed protein are obtained as an aqueous dispersion.

  According to said method, since it becomes possible to coat | cover the surface of an ellagic acid particle with a hydrolyzed protein more uniformly by insolubilizing a hydrolyzed protein below the isoelectric point of a hydrolyzed protein, it is preferable.

  Examples of the pH adjuster include formic acid, acetic acid, lactic acid, malic acid, and citric acid.

  Examples of the dispersant include alkyl sulfate ester salt, polyoxyethylene alkyl ether sulfate ester salt, alkylbenzene sulfonate salt, alkyl diphenyl ether disulfonate salt, alkyl naphthalene sulfonate salt, fatty acid salt, dialkyl sulfosuccinate salt, and alkyl phosphate ester. Salts, anionic surfactants such as polyoxyethylene alkylphenyl phosphate salts; polyoxyethylene alkylphenyl ether, polyoxyethylene alkyl ether, polyoxyethylene fatty acid ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxy Alkylene alkyl ether, polyoxyethylene derivative, glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, polyoxyethylene Nonionic surfactants such as alkylamines, alkyl alkanolamides, or acetylene alcohols, acetylene glycols and their ethylene oxide adducts; cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, alkylbenzylammonium chloride, and alkylamine salts Agents: Water-soluble polymers such as polyvinyl alcohol, methylcellulose, carboxymethylcellulose, gum arabic, polyvinylpyrrolidone, polyacrylate, carrageenan, pectin, casein, gelatin, starch, and hyaluronic acid.

  Moreover, as means for dispersing the particles, a dispersing machine such as a homomixer, a ball mill, or a sand grinder can be used as necessary.

  The amount of the hydrolyzed protein that coats the surface of the ellagic acid particles is not particularly limited, but is preferably 10 to 1000 parts by mass and more preferably 20 to 200 parts by mass with respect to 100 parts by mass of the ellagic acid particles. When the amount of hydrolyzed protein is within the above range, it becomes easy to form a coating layer that sufficiently covers the surface of the ellagic acid particles, and it is possible to reduce the coloration of the textile after washing and to provide sufficient skin protection. Sex can be obtained more reliably.

  The average particle size of the coated ellagic acid particles is preferably 0.1 to 100 μm, and more preferably 0.2 to 10 μm. When the average particle diameter of the coated ellagic acid particles is within the above range, the coated ellagic acid particles can be more uniformly attached to the fibers.

  The coated ellagic acid particles have an average particle diameter of D1 (μm) and the average particle diameter of the coated ellagic acid particles after coating with hydrolyzed protein is D2 (μm). What exists in the range of 001-50.0 is preferable, and what exists in the range of 1.01-5.0 is more preferable. The skin-protecting finish for laundry containing the above-mentioned coated ellagic acid particles can lessen the coloration of the textile after washing, and more reliably obtain sufficient skin protection.

  From the viewpoint of skin protection, the content of the coated ellagic acid particles contained in the laundry skin protective finish of the present invention is preferably 0.001 to 10.0% by mass, and 0.01 to 1.0% by mass. Is more preferable.

  In the skin protective finish for laundry of the present invention, it is preferable to further contain a soft component. Examples of such a flexible component include N-alkylnitrilotriacetic acid, N-alkyldimethylbetaine, α-trimethylammonio fatty acid, N-alkyl β-aminopropionic acid sodium salt, N-alkyl β-iminodipropionic acid. Salt, N-alkyloxymethyl-N, N-diethylbetaine, N-alkyl-N, N-diaminoethylglycine hydrochloride, 2-alkylimidazoline derivative, N-alkylsulfobetaine, N-alkylhydroxysulfobetaine, N -Amphoteric surfactants such as alkyl taurine salt and lecithin; primary amine, acylaminoethyl diethylamine formate, acylaminoethyl diethylamine acetate, acylaminoethyl diethylamine lactate, N-alkyl polyalkylene polyamine salt, fatty acid polyethylene polyol Amide, alkyltrimethylammonium salt, dialkyldimethylammonium salt, alkyldimethylbenzylammonium salt, alkylpyridium salt, acylaminoethylmethyldiethylammonium salt, acylaminopropyldimethylbenzylammonium salt, acylaminopropylmethylhydroxyethylammonium salt, acylamino Ethylpyridinium salt, diacylaminoethylammonium salt, diacyloxyethylmethylhydroxyethylammonium salt, alkyloxymethylpyridium salt, alkylimidazoline, 1-hydroxyethyl-2-alkylimidazolone, 1-acylaminoethyl-2- Alkyl imidazolium salt, alkyl polyoxyethylene amine, N-alkylaminopropylamine, N-alkylamino B pills polyamines, and the like cationic surface active agents such as fatty acid triethanolamine ester. It is preferable to further contain such a soft component because physical irritation to the skin can be reduced.

  In the skin protective finish for laundry of the present invention, the above-mentioned soft component may be used alone or in combination of two or more. Although the compounding quantity of such a soft component is not specifically limited, It is preferable that it is 100-2000 mass parts with respect to 100 mass parts of covering ellagic acid particles, and it is more preferable that it is 100-800 mass parts. When the blending amount of the soft ingredient is within the above range, the action of mitigating the chemical stimulus of the soft ingredient by the coated ellagic acid and the action of mitigating the physical stimulus by the soft ingredient are combined, and the stimulating action of the textile product is comprehensive. Therefore, a higher level of low skin irritation can be achieved.

  The laundry skin protective finish of the present invention contains a viscosity adjuster, a fragrance, a pigment, an antioxidant, a discoloration inhibitor, a chelating agent, an antiseptic, an ultraviolet absorber and the like as long as the skin protection is not impaired. Can do.

  Next, the method for imparting skin protection according to the present invention will be described.

  The skin protection imparting method of the present invention is a method of imparting skin protection to a textile product when washing the textile product, wherein the fiber is rinsed with rinse water containing the laundry skin protecting finish of the present invention. Rinsing the product. More specifically, for example, by adding the aforementioned skin protective finish for washing to the rinsing water in the washing and rinsing step, skin protection can be imparted to the textile.

  Examples of the textile product imparting skin protection include products such as clothing, underwear, foundations, stockings, socks, gloves, sheets, pillow covers, bed covers, and the like that come into direct contact with the skin.

  Although the addition amount of the skin protective finish for laundry of the present invention is not particularly limited, it is usually preferably added to 0.00001 to 5.0% by mass with respect to the textile product in the rinsing bath. It is more preferable to add it so that it may become 0.0001-3.0 mass%. If the addition amount of the skin protective finish for washing applied to the textile product is within the above range, coloring to the textile product after washing can be reduced and sufficient skin protection can be obtained more reliably. .

  EXAMPLES Hereinafter, although an Example and a comparative example are given and this invention is demonstrated further in detail, this invention is not limited at all by these examples.

(Preparation Example 1) (Preparation of hydrolyzed protein-coated ellagic acid particles)
To 43 parts by weight of water, 1 part by weight of ellagic acid (average particle size 0.5 μm), 50 parts by weight of a 15% by weight aqueous solution of hydrolyzed keratin (weight average molecular weight 100,000), and 1 part by weight of dioleyldimethylammonium chloride The mixture was mixed and sonicated for 5 minutes using BRANSON 2200 (manufactured by Yamato Scientific Co., Ltd.). Next, this mixed solution was dispersed using a disperser “Homomixer Mark II” (manufactured by Tokushu Kika). p. At m, 5 parts by weight of 50% aqueous acetic acid solution was gradually added as a pH adjuster to disperse the hydrolyzed protein while insolubilizing it. After completion of the addition of the pH adjuster, the mixture was further dispersed for 10 minutes to obtain an aqueous dispersion of hydrolyzed protein-coated ellagic acid particles.

  About the obtained aqueous dispersion, when the average particle diameter of the dispersion was measured using a laser diffraction particle size distribution analyzer “SALD-1000” (manufactured by Shimadzu Corporation), the average particle diameter was 0.7 μm. there were. Further, when the dispersion was observed at a magnification of 6000 using an electron microscope “scanning electron microscope S-2400” (manufactured by HORIBA), it was confirmed that the ellagic acid particles were coated with the hydrolyzed protein.

(Preparation Examples 2 to 7) (Preparation of hydrolyzed protein-coated ellagic acid particles)
Preparation example as in Preparation Example 1 except that the blending amount of ellagic acid, the type and blending amount of hydrolyzed protein, dispersant and pH adjuster, and the blending amount of water are as shown in Table 1 or 2. Two to seven hydrolyzed protein-coated ellagic acid particle aqueous dispersions were obtained.

  When each of the obtained aqueous dispersions was observed with an electron microscope in the same manner as described above, it was confirmed that the ellagic acid particles were coated with the hydrolyzed protein in any of the aqueous dispersions. Further, the average particle size of the dispersion was measured in the same manner as described above, and the results are shown in Tables 1 and 2.

(Comparative adjustment example 1)
The amount of ellagic acid, the type and amount of hydrolyzed protein and dispersant, and the amount of water shown in Table 2, except that the hydrolyzed protein was not insolubilized without using a pH adjuster. In the same manner as in Example 1, an aqueous dispersion of Comparative Adjustment Example 1 was obtained. The obtained aqueous dispersion was observed with an electron microscope in the same manner as described above, and it was confirmed that the ellagic acid particles were not coated with the hydrolyzed protein. Further, the average particle size of the dispersion was measured in the same manner as described above, and the results are shown in Table 2.

(Comparison adjustment example 2)
Without using hydrolyzed proteins and pH adjusters, ellagic acid, LA9EO and water were mixed and dispersed in the same amounts as shown in Table 2 to obtain an aqueous dispersion of Comparative Adjustment Example 2. It was. Further, the average particle size of the dispersion was measured in the same manner as described above, and the results are shown in Table 2.

In addition, the following were used for each component in Tables 1 and 2.
“Keratin”: A 15% by mass aqueous solution of hydrolyzed keratin [weight average molecular weight 100,000, kerazole, manufactured by Croda Japan Co., Ltd.].
“Wheat A”: 20% by weight aqueous solution of hydrolyzed wheat protein [weight average molecular weight 250,000, tritisol, manufactured by Claude Japan Co., Ltd.].
“Wheat B”: A 10% by mass aqueous solution of hydroxypropylpolysiloxane hydrolyzed wheat protein [weight average molecular weight 500,000, Crodason W, manufactured by Croda Japan Co., Ltd.].
“Wheat C”: 20% by mass aqueous solution of hydrolyzed wheat protein [weight average molecular weight 2,500, clopeptide W, manufactured by Croda Japan Co., Ltd.].
“Silk A”: 20% by mass aqueous solution of hydrolyzed silk [weight average molecular weight 10,000, crosilk 10,000, manufactured by Croda Japan Co., Ltd.].
“Silk B”: A 10% by mass aqueous solution of hydrolyzed silk [weight average molecular weight 35,000, Silken G (registered trademark) Soluble KE (manufactured by Ichimaru Falcos Co., Ltd.) was concentrated and adjusted to 10% by mass].
“OMAC”: Dioleyldimethylammonium chloride.
“LA9EO”: lauryl alcohol ethylene oxide 9 mol adduct.

<Preparation of laundry finish>

(Example 1)
5 parts by mass of the aqueous dispersion obtained in Preparation Example 1 and 95.0 parts by mass of water were uniformly mixed to obtain a skin protective finish for laundry of Example 1.

(Examples 2 to 8)
In the amounts shown in Table 3 or 4, an aqueous dispersion, a soft component, salt and water were uniformly mixed to obtain skin protective finishes for laundry of Examples 2 to 8, respectively.

(Comparative Examples 1 and 2)
In the amounts shown in Table 34, the aqueous dispersion, soft component, salt and water were uniformly mixed to obtain the skin protective finishes for washing of Comparative Examples 1 and 2, respectively.

(Comparative Examples 3 and 4)
With the blending amounts shown in Table 4, the softening ingredients, salt and water were uniformly mixed to obtain the laundry finishing agents of Comparative Examples 3 and 4, respectively.

In addition, the following were used for each component in Tables 3 and 4.
“OMAC”: Dioleyldimethylammonium chloride.
“OIDM”: dimethyl sulfate quaternized product of oleylimidazoline.

<Laundry of textile products>
Using the finishing agents of Examples 1 to 8 and Comparative Examples 1 to 4 obtained above, the textile products were washed under the following conditions, then dehydrated, and air-dried to finish the treated textile products. It was.

Washing machine: Household automatic washing machine Aizuma (registered trademark) [Matsushita Electric Co., Ltd.]
Textile products (laundry): 1000 parts by weight of cotton knit fluorescent fabric with a basis weight of 130 g / m ² Detergent: Attack (registered trademark) [manufactured by Kao Corporation] 25 parts by weight Washing conditions: Bath ratio 1: 20 × 20 ℃ × 10 minutes rinsing condition: bath ratio 1: 20 × 20 ° C. × 5 minutes Finishing agent addition time: Finishing agent addition amount during rinsing: 1.0% by mass with respect to the fiber product

  About the processed fiber product processed using the finishing agent obtained in Examples 1-8 and Comparative Examples 1-4, the coloring degree was evaluated by the following method. The results obtained are shown in Tables 3 and 4.

[Evaluation of coloring degree]
About the obtained processed fiber product, Hunter whiteness was measured using the spectrocolorimeter (MINOLTA CM-3700d), and the coloring degree was evaluated.

  As is clear from the results shown in Tables 3 and 4, according to the skin protective finishes for washing of Examples 1 to 8 containing coated ellagic acid particles in which ellagic acid particles were coated with hydrolyzed protein, Even when it was added at 1.0% by mass with respect to the textile product during the rinsing, it was confirmed that the coloring of the textile product after washing can be sufficiently reduced.

<Granting skin protection to textile products>
Example 9
5 parts by weight of the aqueous dispersion obtained in Preparation Example 1, 10 parts by weight of dioleyldimethylammonium chloride as a soft component, 0.1 part by weight of sodium chloride and 84.9 parts by weight of water are uniformly mixed to provide skin protection for washing. A finish was obtained. Next, after using this skin protective finish for washing, the textile product was washed under the following conditions, then dehydrated and air-dried to obtain a treated textile product.

Washing machine: Household automatic washing machine Aizuma (registered trademark) [Matsushita Electric Co., Ltd.]
Textile products (laundry): 1000 parts by weight of cotton knit fluorescent fabric with a basis weight of 130 g / m ² Detergent: Attack (registered trademark) [manufactured by Kao Corporation] 25 parts by weight Washing conditions: Bath ratio 1: 20 × 20 ℃ × 10 minutes rinsing condition: bath ratio 1: 20 × 20 ° C. × 5 minutes Finishing agent addition time: Finishing agent addition amount during rinsing: 0.2% by mass with respect to the fiber product

(Example 10)
A skin protective finish for washing in the same manner as in Example 9, except that the aqueous dispersion obtained in Preparation Example 3 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. Got. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Example 11)
A skin protective finish for washing in the same manner as in Example 9, except that the aqueous dispersion obtained in Preparation Example 4 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. Got. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

Example 12
A skin-protective finish for washing in the same manner as in Example 9, except that the aqueous dispersion obtained in Preparation Example 5 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. Got. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Example 13)
A skin-protective finish for washing in the same manner as in Example 9, except that the aqueous dispersion obtained in Preparation Example 6 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. Got. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Example 14)
A skin-protective finish for washing in the same manner as in Example 9 except that the aqueous dispersion obtained in Preparation Example 7 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. Got. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Comparative Example 5)
Skin protective finish for washing in the same manner as in Example 9 except that the aqueous dispersion obtained in Comparative Preparation Example 1 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. An agent was obtained. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Comparative Example 6)
Skin protective finish for washing in the same manner as in Example 9 except that the aqueous dispersion obtained in Comparative Preparation Example 2 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 9. An agent was obtained. Next, a treated fiber product was obtained in the same manner as in Example 9 using this washing skin protective finish.

(Comparative Example 7)
A laundry finish was obtained in the same manner as in Example 9 except that the aqueous dispersion obtained in Preparation Example 1 used in Example 9 was not used. Next, a treated fiber product was obtained in the same manner as in Example 9 using this laundry finish.

  The treated fiber products of Examples 9 to 14 and Comparative Examples 5 to 7 obtained above were evaluated for hyaluronidase activity inhibition by the following method. The results obtained are shown in Table 5.

[Evaluation of hyaluronidase activity inhibition]
10 parts by mass of the treated fiber product thus obtained was subjected to Soxhlet extraction with methanol for 3 hours, and then methanol was distilled off from this extract. Next, 5 ml of methanol was added to the distillate to make a solution, and this solution was passed through a column packed with an ion exchange resin (DOWEX 50WX2 50-100, manufactured by Muromachi Technos) to remove the cation component, The methanol in the passing liquid was distilled off, and 10 ml of methanol was added to the distillate to prepare a test sample. Using this test sample, hyaluronidase activity inhibition was evaluated by the following procedure.

  0.2 ml of an enzyme solution prepared by dissolving bovine testicular-derived hyaluronidase in a 0.02M phosphate buffer having a pH of 6.9 to give 10 U / ml, 0.05 ml of the test sample, and 0.15 ml of distilled water Were mixed and incubated at 37 ° C. for 10 minutes, and then immediately ice-cooled. Next, a solution 0 prepared by dissolving sodium hyaluronate (from microorganisms, Sigma) in 0.3 M phosphate buffer having a pH of 5.3 to a sodium hyaluronate concentration of 0.4 mg / ml was added to this mixture. 1 ml was added and incubated at 37 ° C. for 40 minutes. Next, 2.5 ml of an albumin solution prepared so as to be 7.8 mM acetic acid, 40 mM sodium acetate, bovine serum-derived albumin 0.1% by mass, pH 3.75 is added to the solution after incubation, and 5 ml at room temperature. After standing for a minute, this was used as a sample solution, the absorbance at 650 nm was measured, and the hyaluronidase activity inhibition rate was determined by the following formula (1). In addition, methanol was used instead of the test sample as a control solution, methanol was used instead of the test sample as a control solution blank, and distilled water was used instead of the enzyme solution. The higher the hyaluronidase activity inhibition rate, the higher the rough skin prevention effect on the skin.

Hyaluronidase activity inhibition rate (%) = (C ₁ −B ₁ ) / (A ₁ −B ₁ ) × 100
... (1)
[In formula (1), _{A 1} represents the absorbance at 650nm of control solution, _{B 1} represents the absorbance at 650nm of control solution blanks, _{C 1} represents the absorbance at 650nm of the sample solution. ]

  As is clear from the results shown in Table 5, according to the skin protective finishes for washing of Examples 9 to 14 containing coated ellagic acid particles obtained by coating ellagic acid particles with hydrolyzed protein, It was confirmed that a textile product having a sufficiently high hyaluronidase activity inhibitory property was obtained after washing even when it was added at 0.2% by mass with respect to the textile product at the time of rinsing.

(Example 15)
2 parts by weight of the aqueous dispersion obtained in Preparation Example 1, 10 parts by weight of dioleyldimethylammonium chloride as a soft component, 0.1 part by weight of sodium chloride and 87.9 parts by weight of water are uniformly mixed to provide skin protection for washing. A finish was obtained. Next, using this skin protective finish for washing, the textile product was washed under the following conditions, then dehydrated and air-dried to obtain a treated textile product.

Washing machine: Household automatic washing machine Aizuma (registered trademark) [Matsushita Electric Co., Ltd.]
Textile products (laundry): 1000 parts by weight of cotton knit fluorescent fabric with a basis weight of 130 g / m ² Detergent: Attack (registered trademark) [manufactured by Kao Corporation] 25 parts by weight Washing conditions: Bath ratio 1: 20 × 20 ℃ × 10 minutes rinsing condition: bath ratio 1: 20 × 20 ° C. × 5 minutes Finishing agent addition time: Finishing agent addition amount during rinsing: 0.03% by mass with respect to the fiber product

(Example 16)
Skin-protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Preparation Example 3 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. Got. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Example 17)
A skin protective finish for washing in the same manner as in Example 15, except that the aqueous dispersion obtained in Preparation Example 4 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. Got. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Example 18)
A skin-protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Preparation Example 5 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. Got. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Example 19)
A skin protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Preparation Example 6 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. Got. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Example 20)
A skin-protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Preparation Example 7 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. Got. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Comparative Example 8)
Skin protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Comparative Preparation Example 1 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. An agent was obtained. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Comparative Example 9)
Skin protective finish for washing in the same manner as in Example 15 except that the aqueous dispersion obtained in Comparative Preparation Example 2 was used instead of the aqueous dispersion obtained in Preparation Example 1 used in Example 15. An agent was obtained. Next, a treated fiber product was obtained in the same manner as in Example 15 by using this washing skin protective finish.

(Comparative Example 10)
A laundry finish was obtained in the same manner as in Example 15 except that the aqueous dispersion obtained in Preparation Example 1 used in Example 15 was not used. Next, a treated fiber product was obtained in the same manner as in Example 15 using this washing finish.

  About the processed fiber products of Examples 15-20 and Comparative Examples 8-10 obtained above, skin irritation was evaluated by the following method. The results obtained are shown in Table 6.

[Evaluation of skin irritation using cultured skin model]
The obtained treated fiber product was punched with a 7 mm punch in accordance with JIS L1918: 2005, and this was pasted on the surface of the cultured skin [Vitrolife-Skin, manufactured by Gunze Co., Ltd.]. The cells were cultured for 48 hours in a 37 ° C., 5% CO ₂ incubator. Next, the treated fiber product was removed from the cultured skin after culturing, and this cultured skin was washed with 0.01 M phosphate buffered saline, and then the concentration was 0.5 mg / mL MTT (3- (4 bromide). 5-dimethyl-2-thiazolyl) -2,5-diphenyl-2H-tetrazolim) was placed in a 1 ml solution and subjected to a reductase reaction at 37 ° C. in a 5% CO ₂ incubator for 3 hours. After the reaction, it was washed again with phosphate buffered saline, the center of the cultured skin was punched out with a 6 mm punch, and the disc-shaped cultured skin was used as a test specimen. This test specimen was extracted in 1 mL of isopropyl alcohol for 3 hours, the absorbance at 570 nm of the extract was measured, the cell viability was determined by the following formula (2), and skin irritation was evaluated. In addition, as a control test piece, the cultured skin on which the untreated fiber product was affixed was processed in the same procedure as described above and punched into a disk shape. Higher cell viability means less irritation to the skin.

Cell viability (%) = (A ₂ −C ₂ ) / (B ₂ −C ₂ ) × 100 (2)
[In formula (2), A ₂ represents the absorbance at 570 nm of the liquid extracted from the test specimen, B ₂ represents the absorbance at 570 nm of the liquid extracted from the control test specimen, and C ₂ represents the absorbance at 570 nm of the extraction solvent. Absorbance is shown. ]

  As is clear from the results shown in Table 6, according to the skin protective finishes for washing of Examples 15 to 20 containing coated ellagic acid particles in which ellagic acid particles were coated with hydrolyzed protein, Even when it was added so that it might be 0.03 mass% with respect to a textile product at the time of rinsing, it was confirmed that the textile product with low irritation | stimulation with respect to skin is obtained after washing.

  As described above, according to the skin protective finish for laundry of the present invention, excellent skin protection such as prevention of rough skin and prevention of skin irritation can be imparted to a textile product after washing. In addition, according to the skin protective finish for laundry of the present invention, even when added to the rinsing water when washing and rinsing the textile, the discoloration of the textile after washing can be sufficiently reduced. It is possible to sufficiently prevent the product quality from being impaired.

  Therefore, when washing textile products such as clothing, underwear, foundations, stockings, socks, gloves, sheets, pillow covers, bed covers, etc. that come in direct contact with the skin, the skin protective finish for washing of the present invention should be used. Thus, discoloration of the textile product after washing is sufficiently small, and skin protection such as prevention of rough skin and prevention of skin irritation can be sufficiently imparted to the textile product without impairing the quality of the product.

Claims (3)

A skin-protective finish for washing, comprising coated ellagic acid particles obtained by coating the surface of ellagic acid particles with a hydrolyzed protein. 2. The skin protective finish for laundry according to claim 1, wherein the hydrolyzed protein has a weight average molecular weight of 8000 to 800,000. A method of imparting skin protection to a textile product when washing the textile product,
A method for imparting skin protection, comprising the step of rinsing the textile product with rinsing water containing the laundry skin protective finish according to claim 1.