JP2008012213A - Endoscope apparatus for magnified observation - Google Patents

Endoscope apparatus for magnified observation Download PDF

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JP2008012213A
JP2008012213A JP2006188997A JP2006188997A JP2008012213A JP 2008012213 A JP2008012213 A JP 2008012213A JP 2006188997 A JP2006188997 A JP 2006188997A JP 2006188997 A JP2006188997 A JP 2006188997A JP 2008012213 A JP2008012213 A JP 2008012213A
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observation
observation window
window
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normal
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JP4981373B2 (en
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Nobuyuki Saida
信行 斉田
Kohei Iketani
浩平 池谷
Akihiro Takahashi
昭博 高橋
Shinsuke Okada
慎介 岡田
Yoshinobu Numazawa
吉延 沼澤
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Pentax Corp
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Pentax Corp
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Abstract

<P>PROBLEM TO BE SOLVED: To provide an endoscope apparatus for magnified observations for reliably verifying a site subjected to a microscopic magnifying observation by a normal observation image. <P>SOLUTION: In the endoscope apparatus for magnified observations where an observation window 12 for normal observations for loading an observation image of a subject from a position at a distance from the subject and an observation window 14 for magnified observations for taking in a magnified observation image of the subject by abutting on or approaching very closely to a subject's surface are arranged at a distal end 2 of an insertion portion 1, an observation light axis X in front of the observation window 12 is tilted forward of the observation window 14. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

この発明は、被写体の観察像をその被写体との間に距離をおいた位置から取り込むための通常観察用観察窓と、被写体の表面に当接又は極近接されて被写体の顕微鏡的拡大観察像を取り込むための拡大観察用観察窓とが挿入部の先端に併設された拡大観察用内視鏡に関する。   The present invention provides a normal observation observation window for capturing an observation image of a subject from a position at a distance from the subject, and a microscopic enlarged observation image of the subject in contact with or in close proximity to the surface of the subject. The present invention relates to a magnifying observation endoscope in which an observing window for magnifying observation for capturing is provided at the tip of an insertion portion.

体内の管腔臓器内を内視鏡で視覚的に観察して病変等の有無を検査する手技が広く一般に行われている。しかし、そのような内視鏡検査で病変を見つけても、その病変が癌であるか否か等の診断を行うのは困難な場合が多い。   A technique for inspecting the presence or absence of a lesion by visually observing the inside of a luminal organ in the body with an endoscope is widely performed. However, even if a lesion is found by such endoscopy, it is often difficult to make a diagnosis as to whether or not the lesion is cancer.

そこで、内視鏡検査で怪しいと思われた部分については生検鉗子等を用いて組織採取が行われるが、癌でも何でもない場合が大半であるにもかかわらず、単なる検査のために体内の管腔壁の粘膜を損傷させて出血させてしまうことになる。   Therefore, tissues that are considered suspicious by endoscopy are collected using biopsy forceps, etc., but in most cases it is not cancer or anything. It damages the mucous membrane of the lumen wall and causes bleeding.

そこで近年は、例えば共焦点内視鏡等のように1mmに満たない範囲の顕微鏡的拡大像を得ることができる拡大観察用内視鏡が開発され、生検組織を採取することなく、内視鏡による直接観察だけで癌であるか否かの診断を行えるようになってきている(例えば、特許文献1、2、3)。
特開2004−344201 特開2005−80769 特開2005−640
Therefore, in recent years, an endoscope for magnifying observation that can obtain a microscopic magnified image in a range of less than 1 mm, such as a confocal endoscope, has been developed, and an endoscope can be obtained without collecting a biopsy tissue. It has become possible to diagnose whether or not it is cancer only by direct observation with a mirror (for example, Patent Documents 1, 2, and 3).
JP 2004-344201 A JP-A-2005-80769 JP-A-2005-640

顕微鏡的拡大観察像を得ることしかできない単機能の拡大観察用内視鏡では、広い範囲をくまなく観察してその中から怪しい部分を見つけるいわゆるスクリーニング検査を行うことができない。   With a single-function magnifying observation endoscope that can only obtain a microscopic magnified observation image, it is impossible to perform a so-called screening test in which a wide range is observed to find a suspicious part.

そこで、拡大観察用内視鏡には、被写体の観察像をその被写体との間に距離をおいた位置から取り込むための通常観察用観察窓と、被写体の表面に当接又は極近接されて被写体の拡大観察像を取り込むための拡大観察用観察窓とが併設されて、通常観察用観察窓からのスクリーニング検査で異常が疑われる部分を見つけたら、その部位に対して拡大観察用観察窓からの顕微鏡的拡大観察を行うようにしている。   Therefore, the magnifying observation endoscope has a normal observation observation window for capturing an observation image of the subject from a position at a distance from the subject, and the subject in contact with or in close proximity to the surface of the subject. And a magnified observation window for capturing a magnified observation image of the normal observation window. Microscopic observation is performed.

しかし、そのような通常観察用観察窓からの観察と拡大観察用観察窓からの観察との間には視差(パララックス)があるので、通常観察から拡大観察に切り換える際には、通常観察用観察窓からのスクリーニング検査で見つけた異常部分に拡大観察用観察窓を誘導する必要がある。   However, since there is a parallax between the observation from the observation window for normal observation and the observation from the observation window for magnification observation, when switching from normal observation to magnification observation, it is for normal observation. It is necessary to guide the observation window for magnification observation to the abnormal part found by the screening examination from the observation window.

ところが、拡大観察用観察窓を通して得られる顕微鏡的拡大像は細胞レベルのものでスクリーニング検査像とは全く様相が異なるものなので、顕微鏡的拡大観察を行おうとする被写体が実際にスクリーニング検査で異常が疑われた部位なのかどうかはっきりと判断できない問題が生じていた。   However, the microscopic magnified image obtained through the observation window for magnifying observation is at the cellular level and is completely different from the screening examination image. There was a problem in which it was not possible to determine clearly whether the site was broken.

そこで本発明は、顕微鏡的拡大観察の対象部位を通常観察像により確実に確認することができる拡大観察用内視鏡を提供することを目的とする。   Therefore, an object of the present invention is to provide an endoscope for magnification observation that can surely confirm a target site for microscopic magnification observation by a normal observation image.

上記の目的を達成するため、本発明の拡大観察用内視鏡は、挿入部の先端に、被写体の観察像を被写体との間に距離をおいた位置から取り込むための通常観察用観察窓と、被写体の表面に当接又は極近接されて被写体の拡大観察像を取り込むための拡大観察用観察窓とが配置された拡大観察用内視鏡において、通常観察用観察窓から前方の観察光軸を拡大観察用観察窓の前方方向に向けて傾けたものである。   In order to achieve the above object, the endoscope for magnification observation according to the present invention includes an observation window for normal observation for capturing an observation image of a subject from a position at a distance from the subject at the distal end of the insertion portion. In the magnifying observation endoscope in which the magnifying observation observation window for capturing the magnified observation image of the subject in contact with or in close proximity to the surface of the subject is arranged, the observation optical axis in front of the normal observation observation window Is tilted toward the front of the observation window for magnification observation.

なお、拡大観察用観察窓が挿入部の先端部分の軸線に対して垂直の向きに配置され、通常観察用観察窓が拡大観察用観察窓の前方位置に向けて挿入部の先端部分の軸線に対して斜め向きに配置されていてもよい。   The observation window for magnification observation is arranged in a direction perpendicular to the axis of the distal end portion of the insertion portion, and the observation window for normal observation is aligned with the axis of the distal end portion of the insertion portion toward the front position of the observation window for magnification observation. On the other hand, it may be arranged obliquely.

また、拡大観察用観察窓が通常観察用観察窓より前方に出っ張った突出部の先端に配置されていて、通常観察用観察窓と拡大観察用観察窓との間に位置する突出部の壁が透明に形成されていてもよい。   In addition, the observation window for magnification observation is arranged at the tip of the protrusion protruding forward from the observation window for normal observation, and the wall of the protrusion located between the observation window for normal observation and the observation window for magnification observation is It may be formed transparently.

本発明によれば、通常観察用観察窓から前方の観察光軸を拡大観察用観察窓の前方方向に向けて傾けたことにより、拡大観察用観察窓のすぐ前方部分を通常観察用観察窓からの観察画面中に含ませることができるので、通常観察用観察窓からのスクリーニング検査で異常が疑われた部分に対して拡大観察用観察窓からの拡大観察を行う際に、通常観察用観察窓からの観察により、目的部位を見失うことなく拡大観察用観察窓の直前位置に誘導することができ、顕微鏡的拡大観察を、スクリーニング検査で異常が疑われた部位に対して確実に行うことができる。   According to the present invention, the front observation optical axis from the normal observation observation window is tilted toward the front direction of the magnification observation observation window, so that the portion immediately in front of the magnification observation observation window is removed from the normal observation observation window. The observation window for normal observation is used when performing a magnified observation from the observation window for magnification observation on a part suspected of being abnormal in the screening examination from the observation window for normal observation. Can be guided to the position immediately before the observation window for magnified observation without losing sight of the target site, and the microscopic magnified observation can be reliably performed on the site suspected of being abnormal in the screening test. .

挿入部の先端に、被写体の観察像を被写体との間に距離をおいた位置から取り込むための通常観察用観察窓と、被写体の表面に当接又は極近接されて被写体の拡大観察像を取り込むための拡大観察用観察窓とが配置された拡大観察用内視鏡において、通常観察用観察窓から前方の観察光軸を拡大観察用観察窓の前方方向に向けて傾ける。   At the tip of the insertion section, a normal observation observation window for capturing an observation image of the subject from a position spaced from the subject, and an enlarged observation image of the subject in contact with or in close proximity to the surface of the subject In the magnifying observation endoscope in which the magnifying observation observation window is arranged, the observation optical axis in front of the normal observing observation window is tilted toward the front direction of the magnifying observation observation window.

図面を参照して本発明の実施例を説明する。
図2は、本発明の拡大観察用内視鏡の全体構成を略示しており、体内に挿入される可撓性の挿入部1の最先端部に、観察窓や照明窓等が配置された先端部本体2が連結され、挿入部1の基端には、各種操作部材が配置された操作部3が連結されている。
Embodiments of the present invention will be described with reference to the drawings.
FIG. 2 schematically shows the overall configuration of the endoscope for magnification observation according to the present invention, in which an observation window, an illumination window, and the like are arranged at the most distal end portion of the flexible insertion portion 1 to be inserted into the body. The distal end portion body 2 is connected, and the operation portion 3 in which various operation members are arranged is connected to the proximal end of the insertion portion 1.

操作部3から延出するコードの先端には、内視鏡の外部に配置されたビデオプロセッサ5と共焦点像プロセッサ6とに分かれて接続される第1のコネクタ7と第2のコネクタ8とが設けられている。   A first connector 7 and a second connector 8 which are connected to a video processor 5 and a confocal image processor 6 which are arranged outside the endoscope are connected to the tip of a cord extending from the operation unit 3. Is provided.

9は、ビデオプロセッサ5から出力される映像信号による通常観察画像を表示するためのメインモニタ、10は、共焦点像プロセッサ6から出力される映像信号による顕微鏡的拡大観察画像を表示するための拡大像モニタである。   9 is a main monitor for displaying a normal observation image by a video signal output from the video processor 5, and 10 is an enlargement for displaying a microscopic enlarged observation image by a video signal output from the confocal image processor 6. It is an image monitor.

図3は、挿入部1の最先端部分の斜視図であり、先端部本体2の先端には、照明光を放射するための照明窓11と、その照明窓11から放射された照明光により照明された被写体の観察像を被写体との間に距離をおいた位置から取り込むための通常観察用観察窓12とが、斜め前方に向けて並んで配置されている。13は処置具突出口である。なお、送気送水ノズル等の図示は省略されている。   FIG. 3 is a perspective view of the most distal portion of the insertion portion 1. The distal end of the distal end portion main body 2 is illuminated with an illumination window 11 for radiating illumination light and illumination light emitted from the illumination window 11. A normal observation observation window 12 for taking the observed image of the subject taken from a position at a distance from the subject is arranged side by side obliquely forward. Reference numeral 13 denotes a treatment instrument protrusion. In addition, illustration of an air supply / water supply nozzle etc. is abbreviate | omitted.

14は、被写体の表面に当接又は極近接されてその被写体の顕微鏡的拡大観察像を取り込むための拡大観察用観察窓であり、先端部本体2の先端面から前方に突出した突出部2aの先端面に前方に向けて配置されている。   Reference numeral 14 denotes an observation window for magnifying observation that is brought into contact with or in close proximity to the surface of the subject and captures a microscopic magnified observation image of the subject. The magnifying observation window 14 protrudes forward from the tip surface of the tip body 2. It arrange | positions toward the front end surface toward the front.

図1は挿入部1の最先端部分の側面断面図であり、拡大観察用観察窓14は、先端部本体2の軸線に対して垂直の向きに配置されていて、その拡大観察用観察窓14内には共焦点光学系25が配置され、その奥に配置された光学単ファイバ26(シングルモードファイバ)の先端面26aの位置と拡大観察用観察窓14の外表面位置(又は、それよりごく僅かに前方の位置)とが共焦点の位置関係になるようにセットされている。   FIG. 1 is a side cross-sectional view of the most distal portion of the insertion portion 1, and the magnification observation observation window 14 is arranged in a direction perpendicular to the axis of the distal end portion main body 2, and the magnification observation observation window 14. A confocal optical system 25 is arranged inside, and the position of the distal end surface 26a of the optical single fiber 26 (single mode fiber) arranged in the back of the confocal optical system 25 and the position of the outer surface of the observation window 14 for magnification observation (or much more). It is set so that it is in a confocal positional relationship with a slightly forward position.

光学単ファイバ26の先端面26aは、例えば電磁力等を用いた走査機構27により共焦点光学系25の光軸に対して垂直な平面上で2次元的に走査され、光学単ファイバ26内を伝送されてきてその先端面26aから射出されたレーザ光が拡大観察用観察窓14の外表面付近の被写体で焦点を結んでそこから反射されると、その反射光が光学単ファイバ26の先端面26aに焦点を結ぶ。体内の粘膜面に蛍光色素が散布されている場合には、レーザ光により励起された蛍光が被写体になる。   The distal end surface 26a of the optical single fiber 26 is scanned two-dimensionally on a plane perpendicular to the optical axis of the confocal optical system 25 by a scanning mechanism 27 using, for example, electromagnetic force, and the inside of the optical single fiber 26 is scanned. When the laser beam transmitted and emitted from the distal end surface 26a is focused on and reflected from a subject near the outer surface of the observation window 14 for magnification observation, the reflected light is reflected from the distal end surface of the optical single fiber 26. Focus on 26a. When a fluorescent dye is dispersed on the mucosal surface of the body, the fluorescence excited by the laser beam becomes the subject.

したがって、光学単ファイバ26内を通って基端側に戻される反射光をその先端面26aの走査運動に対応する位置に表示させることにより、拡大観察用観察窓14の表面付近の被写体の1mm以下程度の領域(例えば0.5mmの領域)の鮮明な顕微鏡的拡大観察像を得ることができる。ただし、拡大観察用観察窓14内の光学系が、光学単ファイバ26の先端面26aをピンホールの代用とする共焦点光学系25を用いていない、いわゆる通常の拡大観察光学系により顕微鏡的拡大観察を行えるようにしたものであっても差し支えない。   Therefore, the reflected light that returns to the base end side through the optical single fiber 26 is displayed at a position corresponding to the scanning motion of the distal end surface 26a, so that the subject near the surface of the observation window 14 for magnified observation is 1 mm or less. It is possible to obtain a clear microscopic magnified observation image of a certain region (for example, a region of 0.5 mm). However, the optical system in the observation window for magnifying observation 14 does not use the confocal optical system 25 in which the tip surface 26a of the optical single fiber 26 is used as a substitute for a pinhole. It does not matter if it can be observed.

通常観察用観察窓12は拡大観察用観察窓14の前方位置に向けて先端部本体2の軸線対して斜め向きに配置されていて、通常観察用観察窓12の観察光軸Xが、図3にも示されるように、拡大観察用観察窓14の前方方向に向けて傾いた状態になっている。Zは、通常観察用観察窓12から真っ直ぐ前方方向(先端部本体2の軸線と平行方向)を示している。   The observation window for normal observation 12 is disposed obliquely with respect to the axis of the tip body 2 toward the front position of the observation window for magnification observation 14, and the observation optical axis X of the observation window for normal observation 12 is shown in FIG. As shown also in FIG. 2, it is in a state of being inclined toward the front direction of the observation window 14 for magnification observation. Z indicates a forward direction (a direction parallel to the axis of the tip portion main body 2) straight from the observation window 12 for normal observation.

図1に示されるように、そのような通常観察用観察窓12内には、広い視野角(例えば100°〜140°程度)を得るための対物光学系21が配置されて、その対物光学系21による被写体の投影位置に固体撮像素子22の撮像面が配置されている。23は、固体撮像素子22で得られた撮像信号を伝送するための信号ケーブルである。   As shown in FIG. 1, an objective optical system 21 for obtaining a wide viewing angle (for example, about 100 ° to 140 °) is arranged in the observation window 12 for normal observation. The imaging surface of the solid-state imaging device 22 is arranged at the projection position of the subject by 21. Reference numeral 23 denotes a signal cable for transmitting an imaging signal obtained by the solid-state imaging device 22.

対物光学系21には光軸を偏角させるための偏角プリズム21pが含まれており、通常観察用観察窓12から前方に向かう観察光軸Xが、通常観察用観察窓12より前方では先端部本体2の軸線と平行な方向(図3に示されるZ方向)に対して例えば30°程度斜めに傾けられている。   The objective optical system 21 includes a declination prism 21p for deflecting the optical axis, and the observation optical axis X heading forward from the normal observation observation window 12 is the tip at the front of the normal observation observation window 12. For example, it is inclined at about 30 ° with respect to a direction parallel to the axis of the main part 2 (Z direction shown in FIG. 3).

その結果、通常観察用観察窓12を通して得られる通常観察の領域は、図1に示されるように、通常観察用観察窓12の真っ直ぐ前方方向Zを含むと同時に、拡大観察用観察窓14が設けられている突出部2aの側壁部分を含んでいる。   As a result, the normal observation region obtained through the normal observation observation window 12 includes a straight forward direction Z of the normal observation observation window 12 as shown in FIG. The side wall portion of the protruding portion 2a is included.

そして、この実施例においては、通常観察用観察窓12からの観察領域に含まれる先端部本体2の突出部2aの壁が透明なプラスチック材によって形成されている(透明壁部15)。なお、図3にはその外観が図示されている。その結果、その突出部2aの部分が不透明であれば遮られることになる拡大観察用観察窓14のすぐ前方位置にある被写体を、通常観察用観察窓12からの通常観察で観察することができる。   In this embodiment, the wall of the protruding portion 2a of the tip body 2 included in the observation region from the normal observation window 12 is formed of a transparent plastic material (transparent wall portion 15). In addition, the external appearance is illustrated in FIG. As a result, the subject located immediately in front of the observation window for magnification observation 14 that is blocked if the protruding portion 2a is opaque can be observed by normal observation from the observation window for normal observation 12. .

このようにして、通常観察用観察窓12を通しての通常観察により、挿入部1の先端から遠い前方領域のスクリーニング検査を行うことができると同時に、拡大観察用観察窓14のすぐ前方部分がその観察画面中に含まれるので、通常観察用観察窓12からのスクリーニング検査で異常が疑われる部分を見つけて、その部分に対して拡大観察用観察窓14からの拡大観察を行う場合には、通常観察用観察窓12からの観察により、目的部位を見失うことなく拡大観察用観察窓14の直前位置に誘導することができ、顕微鏡的拡大観察を、スクリーニング検査で異常が疑われた部位に対して確実に行うことができる。   In this way, a normal examination through the observation window for normal observation 12 enables a screening examination of the front region far from the distal end of the insertion portion 1, and at the same time, the portion immediately in front of the observation window for magnification observation 14 is observed. Since it is included in the screen, when a portion suspected of being abnormal is found in the screening examination from the observation window for normal observation 12 and magnified observation from the observation window for magnification observation 14 is performed on that portion, normal observation is performed. By observing from the observation window 12 for observation, it is possible to guide to the position immediately before the observation window 14 for magnification observation without losing sight of the target part, and the microscopic magnification observation is surely performed on the part suspected of being abnormal in the screening examination. Can be done.

本発明の実施例の拡大観察用内視鏡の挿入部の先端部分の側面断面図である。It is side surface sectional drawing of the front-end | tip part of the insertion part of the endoscope for magnification observation of the Example of this invention. 本発明の実施例の拡大観察用内視鏡の全体構成を示す略示図である。It is a schematic diagram showing the whole composition of the endoscope for magnification observation of the example of the present invention. 本発明の実施例の拡大観察用内視鏡の挿入部の先端部分の斜視図である。It is a perspective view of the front-end | tip part of the insertion part of the endoscope for magnification observation of the Example of this invention.

符号の説明Explanation of symbols

1 挿入部
2 先端部本体
2a 突出部
12 通常観察用観察窓
14 拡大観察用観察窓
15 透明壁部
21 対物光学系
21p 偏角プリズム
22 固体撮像素子
25 共焦点光学系
26 光学単ファイバ
26a 先端面
X 観察光軸
Z 前方方向
DESCRIPTION OF SYMBOLS 1 Insertion part 2 Front-end | tip part main body 2a Protrusion part 12 Observation window for normal observation 14 Observation window for expansion observation 15 Transparent wall part 21 Objective optical system 21p Deflection prism 22 Solid-state image sensor 25 Confocal optical system 26 Optical single fiber 26a Tip surface X Observation optical axis Z Forward direction

Claims (3)

挿入部の先端に、被写体の観察像を上記被写体との間に距離をおいた位置から取り込むための通常観察用観察窓と、上記被写体の表面に当接又は極近接されて上記被写体の拡大観察像を取り込むための拡大観察用観察窓とが配置された拡大観察用内視鏡において、
上記通常観察用観察窓から前方の観察光軸を上記拡大観察用観察窓の前方方向に向けて傾けたことを特徴とする拡大観察用内視鏡。
A normal observation observation window for capturing an observation image of the subject from a position at a distance from the subject at the distal end of the insertion portion, and an enlarged observation of the subject in contact with or in close proximity to the surface of the subject In an endoscope for magnification observation in which an observation window for magnification observation for capturing an image is arranged,
An endoscope for magnification observation, wherein an observation optical axis in front of the observation window for normal observation is tilted toward the front direction of the observation window for magnification observation.
上記拡大観察用観察窓が上記挿入部の先端部分の軸線に対して垂直の向きに配置され、上記通常観察用観察窓が上記拡大観察用観察窓の前方位置に向けて上記挿入部の先端部分の軸線に対して斜め向きに配置されている請求項1記載の拡大観察用内視鏡。   The observation window for magnified observation is arranged in a direction perpendicular to the axis of the distal end portion of the insertion portion, and the distal end portion of the insertion portion is directed toward the front position of the observation window for magnification observation. The endoscope for magnifying observation according to claim 1, wherein the endoscope is disposed obliquely with respect to the axis. 上記拡大観察用観察窓が上記通常観察用観察窓より前方に出っ張った突出部の先端に配置されていて、上記通常観察用観察窓と上記拡大観察用観察窓との間に位置する上記突出部の壁が透明に形成されている請求項1又は2記載の拡大観察用内視鏡。   The enlarged observation window is disposed at the tip of a protruding part protruding forward from the normal observation window, and is located between the normal observation window and the enlarged observation window. The endoscope for magnifying observation according to claim 1 or 2, wherein said wall is formed transparent.
JP2006188997A 2006-07-10 2006-07-10 Magnifying endoscope Expired - Fee Related JP4981373B2 (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009233244A (en) * 2008-03-28 2009-10-15 Fujinon Corp Optical unit for probe and its assembling method
JP2012090741A (en) * 2010-10-26 2012-05-17 Fujifilm Corp Endoscope device

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09122068A (en) * 1995-10-31 1997-05-13 Olympus Optical Co Ltd Endoscope apparatus
JP2001275953A (en) * 2000-03-30 2001-10-09 Asahi Optical Co Ltd Multiview endoscope
JP2003290128A (en) * 2002-03-29 2003-10-14 Olympus Optical Co Ltd Sentinel lymph node-detecting method
JP2004166913A (en) * 2002-11-19 2004-06-17 Olympus Corp Optical observation probe and endoscope observation instrument
JP2004350848A (en) * 2003-05-28 2004-12-16 Olympus Corp Endoscopic device
JP2005118133A (en) * 2003-10-14 2005-05-12 Olympus Corp Ultrasonic endoscope, observation probe, and endoscopic observation apparatus

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09122068A (en) * 1995-10-31 1997-05-13 Olympus Optical Co Ltd Endoscope apparatus
JP2001275953A (en) * 2000-03-30 2001-10-09 Asahi Optical Co Ltd Multiview endoscope
JP2003290128A (en) * 2002-03-29 2003-10-14 Olympus Optical Co Ltd Sentinel lymph node-detecting method
JP2004166913A (en) * 2002-11-19 2004-06-17 Olympus Corp Optical observation probe and endoscope observation instrument
JP2004350848A (en) * 2003-05-28 2004-12-16 Olympus Corp Endoscopic device
JP2005118133A (en) * 2003-10-14 2005-05-12 Olympus Corp Ultrasonic endoscope, observation probe, and endoscopic observation apparatus

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009233244A (en) * 2008-03-28 2009-10-15 Fujinon Corp Optical unit for probe and its assembling method
JP2012090741A (en) * 2010-10-26 2012-05-17 Fujifilm Corp Endoscope device

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