JP2007537299A5 - - Google Patents

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Publication number
JP2007537299A5
JP2007537299A5 JP2007513459A JP2007513459A JP2007537299A5 JP 2007537299 A5 JP2007537299 A5 JP 2007537299A5 JP 2007513459 A JP2007513459 A JP 2007513459A JP 2007513459 A JP2007513459 A JP 2007513459A JP 2007537299 A5 JP2007537299 A5 JP 2007537299A5
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JP
Japan
Prior art keywords
antibody
drug
medicament
medicament according
allograft
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2007513459A
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English (en)
Japanese (ja)
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JP2007537299A (ja
JP5161567B2 (ja
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Publication date
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Priority claimed from PCT/US2005/017048 external-priority patent/WO2005110481A2/en
Publication of JP2007537299A publication Critical patent/JP2007537299A/ja
Publication of JP2007537299A5 publication Critical patent/JP2007537299A5/ja
Application granted granted Critical
Publication of JP5161567B2 publication Critical patent/JP5161567B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2007513459A 2004-05-14 2005-05-16 補体活性を阻害することによる同種移植片の生存の延長 Expired - Lifetime JP5161567B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57144404P 2004-05-14 2004-05-14
US60/571,444 2004-05-14
PCT/US2005/017048 WO2005110481A2 (en) 2004-05-14 2005-05-16 Prolongation of survival of an allograft by inhibiting complement activity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012246213A Division JP5590624B2 (ja) 2004-05-14 2012-11-08 補体活性を阻害することによる同種移植片の生存の延長

Publications (3)

Publication Number Publication Date
JP2007537299A JP2007537299A (ja) 2007-12-20
JP2007537299A5 true JP2007537299A5 (https=) 2008-07-03
JP5161567B2 JP5161567B2 (ja) 2013-03-13

Family

ID=35385551

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2007513459A Expired - Lifetime JP5161567B2 (ja) 2004-05-14 2005-05-16 補体活性を阻害することによる同種移植片の生存の延長
JP2012246213A Expired - Lifetime JP5590624B2 (ja) 2004-05-14 2012-11-08 補体活性を阻害することによる同種移植片の生存の延長
JP2014021907A Withdrawn JP2014080438A (ja) 2004-05-14 2014-02-07 補体活性を阻害することによる同種移植片の生存の延長

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012246213A Expired - Lifetime JP5590624B2 (ja) 2004-05-14 2012-11-08 補体活性を阻害することによる同種移植片の生存の延長
JP2014021907A Withdrawn JP2014080438A (ja) 2004-05-14 2014-02-07 補体活性を阻害することによる同種移植片の生存の延長

Country Status (14)

Country Link
US (3) US20090028850A1 (https=)
EP (4) EP3056218A1 (https=)
JP (3) JP5161567B2 (https=)
AU (1) AU2005244012C1 (https=)
CA (1) CA2566716C (https=)
DK (1) DK1755674T3 (https=)
ES (1) ES2528362T3 (https=)
HK (2) HK1222342A1 (https=)
IL (2) IL179240A (https=)
NZ (1) NZ551308A (https=)
PL (1) PL1755674T3 (https=)
PT (1) PT1755674E (https=)
SI (1) SI1755674T1 (https=)
WO (1) WO2005110481A2 (https=)

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ES2528362T3 (es) 2004-05-14 2015-02-09 Alexion Pharmaceuticals, Inc. Prolongación de la supervivencia de un aloinjerto por inhibición de la actividad del complemento
RS53864B1 (sr) * 2006-03-02 2015-08-31 Alexion Pharmaceuticals, Inc. Produžavanje preživljavanja alografta inhibiranjem aktivnosti komplementa
PL3167888T3 (pl) 2006-03-15 2024-08-26 Alexion Pharmaceuticals, Inc. Leczenie pacjentów z napadową nocną hemoglobinurią za pomocą inhibitora dopełniacza
LT3028716T (lt) 2006-10-10 2020-12-10 Regenesance B.V. Komplemento slopinimas nervų regeneracijos pagerinimui
LT2894165T (lt) * 2008-11-10 2023-03-10 Alexion Pharmaceuticals, Inc. Būdai ir kompozicijos, skirti su komplementu susijusių sutrikimų gydymui
US20110110953A1 (en) * 2009-06-29 2011-05-12 Dennis Keith Bishop Compound and method for treatment of chronic transplant rejection
JP5871798B2 (ja) * 2009-07-02 2016-03-01 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント 肝再生を刺激する方法
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
WO2011146395A2 (en) * 2010-05-17 2011-11-24 The Board Of Trustees Of The Leland Stanford Junior University Prevention of immunological rejection of transplanted stem cells by leukocyte costimulatory molecule blockade
CA2881981A1 (en) 2012-08-20 2014-02-27 Fred Hutchinson Cancer Research Center Method and compositions for cellular immunotherapy
AU2014306002B2 (en) 2013-08-07 2017-05-25 Alexion Pharmaceuticals, Inc. Atypical hemolytic uremic syndrome (aHUS) biomarker proteins
US20160184391A1 (en) 2013-08-16 2016-06-30 Alexion Pharmaceuticals, Inc. Treatment of graft rejection by administering a complement inhibitor to an organ prior to transplant
WO2016061066A1 (en) 2014-10-15 2016-04-21 Alexion Pharmaceuticals, Inc. Methods of replicating a large scale eculizumab production cell culture
US20180311299A1 (en) * 2015-05-01 2018-11-01 Alexion Pharmaceuticals, Inc. Efficacy of an anti-c5 antibody in the prevention of antibody mediated rejection in sensitized recipients of a kidney transplant
ES2984352T3 (es) 2016-06-14 2024-10-29 Regeneron Pharma Anticuerpos anti-C5 y usos de los mismos
MA51147A (fr) 2017-12-13 2021-03-24 Regeneron Pharma Associations d'anticorps anti-c5 et utilisations associées
US20190247560A1 (en) 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
GB201911931D0 (en) * 2019-08-20 2019-10-02 Univ College Cardiff Consultants Ltd Anti-C7 antibody or antibody fragment
US20210353685A1 (en) * 2020-05-14 2021-11-18 Brain Cancer Research Institute Augmentation of Cell Therapy Efficacy by Inhibition of Complement Activation Pathways
CN114532982A (zh) * 2022-01-12 2022-05-27 高谋 评价干细胞系统移植调控补体活化作用的体系
KR20250120401A (ko) * 2022-12-08 2025-08-08 주식회사 노브메타파마 이식물 및 수혜자의 생존을 연장하기 위한 조성물 및 방법

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US5135916A (en) 1989-06-12 1992-08-04 Oklahoma Medical Research Foundation Inhibition of complement mediated inflammatory response
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US20010018051A1 (en) * 1990-04-09 2001-08-30 White David James Graham Inhibition of allograft and concordant xenograft rejection
WO1992010205A1 (en) * 1990-12-06 1992-06-25 T Cell Sciences, Inc. Synergistic compositions of soluble complement receptors and compounds that inhibit complement and/or suppress immune activity
US5456909A (en) * 1992-08-07 1995-10-10 T Cell Sciences, Inc. Glycoform fractions of recombinant soluble complement receptor 1 (sCR1) having extended half-lives in vivo
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BRPI0211953B8 (pt) * 2001-08-17 2021-05-25 Genentech Inc anticorpo monoclonal ou fragmento de ligação a antígeno que se liga a c5 e c5a sem a prevenção da formação de c5b, linhagem celular, composição farmacêutica, bem como método in vitro para inibir a atividade de c5a e método de diagnóstico in vitro
AU2003209308A1 (en) * 2002-01-22 2003-09-02 Genzyme Corporation Use of tgf-beta antagonists to treat or to prevent chronic transplant rejection
WO2005025509A2 (en) * 2003-09-11 2005-03-24 Board Of Regents, The University Of Texas System Methods and materials for treating autoimmune diseases and conditions
US20050169921A1 (en) * 2004-02-03 2005-08-04 Leonard Bell Method of treating hemolytic disease
ES2528362T3 (es) 2004-05-14 2015-02-09 Alexion Pharmaceuticals, Inc. Prolongación de la supervivencia de un aloinjerto por inhibición de la actividad del complemento
EP1781267A4 (en) * 2004-05-17 2009-03-11 Combinatorx Inc METHOD AND REAGENTS FOR THE TREATMENT OF INFAMOUS DISEASES

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