JP2007532544A5 - - Google Patents
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- Publication number
- JP2007532544A5 JP2007532544A5 JP2007507367A JP2007507367A JP2007532544A5 JP 2007532544 A5 JP2007532544 A5 JP 2007532544A5 JP 2007507367 A JP2007507367 A JP 2007507367A JP 2007507367 A JP2007507367 A JP 2007507367A JP 2007532544 A5 JP2007532544 A5 JP 2007532544A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- amount
- alkylamine
- component
- multipurpose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000243 solution Substances 0.000 claims description 83
- 150000003973 alkyl amines Chemical class 0.000 claims description 35
- 230000000845 anti-microbial effect Effects 0.000 claims description 21
- 239000002736 nonionic surfactant Substances 0.000 claims description 19
- 125000000217 alkyl group Chemical group 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 14
- FJLUATLTXUNBOT-UHFFFAOYSA-N 1-Hexadecylamine Chemical compound CCCCCCCCCCCCCCCCN FJLUATLTXUNBOT-UHFFFAOYSA-N 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 13
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 12
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 239000000872 buffer Substances 0.000 claims description 9
- 239000004599 antimicrobial Substances 0.000 claims description 8
- PLZVEHJLHYMBBY-UHFFFAOYSA-N Tetradecylamine Chemical compound CCCCCCCCCCCCCCN PLZVEHJLHYMBBY-UHFFFAOYSA-N 0.000 claims description 7
- 229920001400 block copolymer Polymers 0.000 claims description 7
- 230000001939 inductive effect Effects 0.000 claims description 7
- 229960003080 taurine Drugs 0.000 claims description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 5
- 239000001913 cellulose Substances 0.000 claims description 5
- 229920002678 cellulose Polymers 0.000 claims description 5
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- -1 poly (oxyethylene) Polymers 0.000 claims description 4
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 2
- 239000001103 potassium chloride Substances 0.000 claims description 2
- 235000011164 potassium chloride Nutrition 0.000 claims description 2
- 239000011780 sodium chloride Substances 0.000 claims description 2
- 230000003472 neutralizing effect Effects 0.000 claims 3
- 238000004140 cleaning Methods 0.000 claims 1
- 238000000034 method Methods 0.000 description 11
- 239000000126 substance Substances 0.000 description 9
- 239000004094 surface-active agent Substances 0.000 description 9
- 229940123208 Biguanide Drugs 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- 210000000170 cell membrane Anatomy 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 229920001090 Polyaminopropyl biguanide Polymers 0.000 description 2
- 239000007983 Tris buffer Substances 0.000 description 2
- LFVVNPBBFUSSHL-UHFFFAOYSA-N alexidine Chemical class CCCCC(CC)CNC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NCC(CC)CCCC LFVVNPBBFUSSHL-UHFFFAOYSA-N 0.000 description 2
- 229950010221 alexidine Drugs 0.000 description 2
- 125000000656 azaniumyl group Chemical group [H][N+]([H])([H])[*] 0.000 description 2
- 150000004283 biguanides Chemical class 0.000 description 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 description 2
- 229940093424 polyaminopropyl biguanide Drugs 0.000 description 2
- RXGSAYBOEDPICZ-UHFFFAOYSA-N 2-[6-[[amino-(diaminomethylideneamino)methylidene]amino]hexyl]-1-(diaminomethylidene)guanidine Chemical compound NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)N RXGSAYBOEDPICZ-UHFFFAOYSA-N 0.000 description 1
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 description 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical class C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 239000004155 Chlorine dioxide Substances 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229920002413 Polyhexanide Polymers 0.000 description 1
- 229920000289 Polyquaternium Polymers 0.000 description 1
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 1
- 229960001716 benzalkonium Drugs 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 239000006172 buffering agent Substances 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 235000019398 chlorine dioxide Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 239000000411 inducer Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/820,354 US7157412B2 (en) | 2004-04-07 | 2004-04-07 | Alkylamine as an antimicrobial agent in ophthalmic compositions |
| US10/820,354 | 2004-04-07 | ||
| PCT/US2005/010698 WO2005099779A1 (en) | 2004-04-07 | 2005-03-30 | Alkylamine as an antimicrobial agent in ophthalmic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007532544A JP2007532544A (ja) | 2007-11-15 |
| JP2007532544A5 true JP2007532544A5 (https=) | 2008-05-15 |
| JP4989459B2 JP4989459B2 (ja) | 2012-08-01 |
Family
ID=34965139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007507367A Expired - Fee Related JP4989459B2 (ja) | 2004-04-07 | 2005-03-30 | 眼科用組成物における抗微生物剤としてのアルキルアミン |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7157412B2 (https=) |
| EP (1) | EP1732617B1 (https=) |
| JP (1) | JP4989459B2 (https=) |
| CN (1) | CN100512884C (https=) |
| AU (1) | AU2005232566C1 (https=) |
| BR (1) | BRPI0509651A (https=) |
| CA (1) | CA2562267C (https=) |
| ES (1) | ES2304864B1 (https=) |
| WO (1) | WO2005099779A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2602411C (en) | 2005-03-23 | 2015-02-24 | Oculus Innovative Sciences, Inc. | Method of treating second and third degree burns using oxidative reductive potential water solution |
| CA2637178C (en) | 2006-01-20 | 2018-09-04 | Oculus Innovative Sciences, Inc. | Methods of preventing or treating sinusitis with oxidative reductive potential water solution |
| US20070264226A1 (en) * | 2006-05-10 | 2007-11-15 | Karagoezian Hampar L | Synergistically enhanced disinfecting solutions |
| US20080214421A1 (en) * | 2007-02-19 | 2008-09-04 | Fang Zhao | Contact lens care composition |
| TWI607705B (zh) * | 2008-05-26 | 2017-12-11 | 大幸藥品股份有限公司 | 忌避劑、刺咬忌避劑及節肢動物媒介病預防劑 |
| WO2010148004A1 (en) * | 2009-06-15 | 2010-12-23 | Oculus Innovative Sciences, Inc. | Solution containing hypochlorous acid and methods of using same |
| US8335127B2 (en) * | 2009-08-12 | 2012-12-18 | Pgs Geophysical As | Method for generating spread spectrum driver signals for a seismic vibrator array using multiple biphase modulation operations in each driver signal chip |
| CN103719142B (zh) * | 2012-10-10 | 2015-09-16 | 俞致健 | 一种消毒剂及其制备方法与应用 |
| CN108700676B (zh) * | 2016-02-22 | 2021-01-01 | 库柏维景国际控股公司 | 润滑性改进的硅酮水凝胶隐形眼镜 |
| US10925894B2 (en) * | 2017-05-05 | 2021-02-23 | Gregory J. PAMEL | Composition containing chlorine dioxide and methods for using same |
| GB201813229D0 (en) | 2018-08-14 | 2018-09-26 | Ocutec Ltd | Formulation |
| CN115282349A (zh) * | 2022-07-05 | 2022-11-04 | 复旦大学附属眼耳鼻喉科医院 | 一种有利于改善孟加拉玫瑰红-绿光角膜胶原交联技术中cct降低的角膜交联试剂 |
| US20240166971A1 (en) * | 2022-10-26 | 2024-05-23 | Bausch + Lomb Ireland Limited | Contact lens treating solution |
| CN117230437B (zh) * | 2023-08-09 | 2025-12-02 | 山东科技大学 | 镁合金基材表面edta辅助低温水浴mao/ldh杂化涂层的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3542970A1 (de) * | 1985-12-05 | 1987-06-11 | Benckiser Gmbh Joh A | Fluessige sanitaerreinigungs- und entkalkungsmittel und verfahren zu deren herstellung |
| AU6667894A (en) * | 1993-04-28 | 1994-11-21 | Alcon Laboratories, Inc. | Diamines as antimicrobial agents and use thereof in ophthalmic composition |
| US5935518A (en) | 1996-01-29 | 1999-08-10 | Bausch & Lomb Incorporated | Swimming pool treatment |
| JP3706216B2 (ja) * | 1996-12-05 | 2005-10-12 | 株式会社トーメー | コンタクトレンズ用剤 |
| PT948357E (pt) * | 1996-12-13 | 2002-10-31 | Alcon Lab Inc | Utilizacao de amino alcoois de baixo peso molecular em composicoes oftalmicas |
| US6063745A (en) * | 1997-11-26 | 2000-05-16 | Allergan | Mutli-purpose contact lens care compositions |
| US6162371A (en) * | 1997-12-22 | 2000-12-19 | S. C. Johnson & Son, Inc. | Stabilized acidic chlorine bleach composition and method of use |
| JPH11281937A (ja) * | 1998-03-27 | 1999-10-15 | Menicon Co Ltd | コンタクトレンズ用剤 |
| EP0982394A1 (en) * | 1998-08-27 | 2000-03-01 | The Procter & Gamble Company | Liquid neutral or alkaline hard-surface cleaning composition |
| EP1214883B1 (en) | 1999-09-20 | 2003-11-26 | Menicon Co., Ltd. | Liquid preparation for contact lenses |
| DE60118179D1 (de) | 2000-06-02 | 2006-05-11 | Arch Chem Inc | Behandlung von zirkulierenden wassersystemen |
| US20030153475A1 (en) | 2001-12-20 | 2003-08-14 | Zhenze Hu | Composition for treating contact lenses |
| US20040120916A1 (en) | 2002-12-23 | 2004-06-24 | Advanced Medical Optics, Inc. | Contact lens care compositions, methods of use and preparation which protect ocular tissue membrane integrity |
| US20050095215A1 (en) * | 2003-11-03 | 2005-05-05 | Popp Karl F. | Antimicrobial shampoo compositions |
-
2004
- 2004-04-07 US US10/820,354 patent/US7157412B2/en not_active Expired - Lifetime
-
2005
- 2005-03-30 WO PCT/US2005/010698 patent/WO2005099779A1/en not_active Ceased
- 2005-03-30 JP JP2007507367A patent/JP4989459B2/ja not_active Expired - Fee Related
- 2005-03-30 CA CA2562267A patent/CA2562267C/en not_active Expired - Fee Related
- 2005-03-30 CN CNB2005800096802A patent/CN100512884C/zh not_active Expired - Fee Related
- 2005-03-30 EP EP05733007.8A patent/EP1732617B1/en not_active Expired - Lifetime
- 2005-03-30 AU AU2005232566A patent/AU2005232566C1/en not_active Ceased
- 2005-03-30 BR BRPI0509651-0A patent/BRPI0509651A/pt not_active Application Discontinuation
- 2005-03-31 ES ES200650069A patent/ES2304864B1/es not_active Expired - Fee Related
-
2006
- 2006-09-25 US US11/534,990 patent/US7488706B2/en not_active Expired - Lifetime
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