JP2007529471A - 新規のｎ−（アルコキシアルキル）カルバモイル置換された６−フェニル−ベンゾナフチリジン誘導体及びｐｄｅ３／４インヒビターとしてのそれらの使用 - Google Patents

新規のｎ−（アルコキシアルキル）カルバモイル置換された６−フェニル−ベンゾナフチリジン誘導体及びｐｄｅ３／４インヒビターとしてのそれらの使用 Download PDF

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Publication number
JP2007529471A
JP2007529471A JP2007503345A JP2007503345A JP2007529471A JP 2007529471 A JP2007529471 A JP 2007529471A JP 2007503345 A JP2007503345 A JP 2007503345A JP 2007503345 A JP2007503345 A JP 2007503345A JP 2007529471 A JP2007529471 A JP 2007529471A
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Japan
Prior art keywords
alkyl
alkoxy
methyl
formula
hydrogen
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Withdrawn
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JP2007503345A
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English (en)
Japanese (ja)
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JP2007529471A5 (enExample
Inventor
フロッケルツィ ディーター
カウツ ウルリッヒ
アルミン　ハッツェルマン
バルズィヒ ヨハネス
デーゲンハルト　マルクス
ハンス−ペーター　クライ
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Takeda GmbH
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Altana Pharma AG
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Publication date
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Publication of JP2007529471A publication Critical patent/JP2007529471A/ja
Publication of JP2007529471A5 publication Critical patent/JP2007529471A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2007503345A 2004-03-17 2005-03-16 新規のｎ−（アルコキシアルキル）カルバモイル置換された６−フェニル−ベンゾナフチリジン誘導体及びｐｄｅ３／４インヒビターとしてのそれらの使用 Withdrawn JP2007529471A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04101101 2004-03-17
EP04101111 2004-03-18
PCT/EP2005/051204 WO2005090345A1 (en) 2004-03-17 2005-03-16 Novel n- (alkoxyalkyl) carbamoyl - substituted 6-phenyl-benzonaphthyridine derivatives and their use as pde3/4 inhibitors

Publications (2)

Publication Number Publication Date
JP2007529471A true JP2007529471A (ja) 2007-10-25
JP2007529471A5 JP2007529471A5 (enExample) 2008-05-08

Family

ID=34962090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007503345A Withdrawn JP2007529471A (ja) 2004-03-17 2005-03-16 新規のｎ−（アルコキシアルキル）カルバモイル置換された６−フェニル−ベンゾナフチリジン誘導体及びｐｄｅ３／４インヒビターとしてのそれらの使用

Country Status (6)

Country Link
US (1) US7671068B2 (enExample)
EP (1) EP1732925A1 (enExample)
JP (1) JP2007529471A (enExample)
AU (1) AU2005223386A1 (enExample)
CA (1) CA2559200A1 (enExample)
WO (1) WO2005090345A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017527569A (ja) * 2014-09-03 2017-09-21 シー４エックス・ディスカヴァリー・リミテッド オレキシン−１受容体の阻害剤としての治療用化合物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
US20100041662A1 (en) 2006-10-30 2010-02-18 Sandrine Ferrand Heterocyclic compounds as antiinflammatory agents
WO2009087224A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
JP5959541B2 (ja) 2011-02-25 2016-08-02 ノバルティス アーゲー Ｔｒｋ阻害剤としてのピラゾロ［１，５−ａ］ピリジン
GB201601703D0 (en) 2016-01-29 2016-03-16 C4X Discovery Ltd Therapeutic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE234300T1 (de) 1996-11-11 2003-03-15 Altana Pharma Ag Benzonaphthyridine als bronchialtherapeutika
WO1998040382A1 (en) 1997-03-07 1998-09-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
DE59904535D1 (de) 1998-05-05 2003-04-17 Altana Pharma Ag Neue Benzonaphtyridin-N-oxide
US6436952B1 (en) 1998-08-31 2002-08-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine-N-oxides comprising a PDE3 and PDE4 inhibiting activity
PT1377574E (pt) 2001-02-21 2005-05-31 Byk Gulden Lomberg Chem Fab 6-fenilbenzonaftiridinas
JP2005537313A (ja) 2002-08-17 2005-12-08 アルタナ　ファルマ　アクチエンゲゼルシャフト 新規のベンゾナフチリジン

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017527569A (ja) * 2014-09-03 2017-09-21 シー４エックス・ディスカヴァリー・リミテッド オレキシン−１受容体の阻害剤としての治療用化合物

Also Published As

Publication number Publication date
WO2005090345A1 (en) 2005-09-29
US20070208051A1 (en) 2007-09-06
CA2559200A1 (en) 2005-09-29
AU2005223386A1 (en) 2005-09-29
EP1732925A1 (en) 2006-12-20
US7671068B2 (en) 2010-03-02

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