JP2007525988A - O6−アルキルグアニン−dnaアルキルトランスフェラーゼの突然変異体 - Google Patents

O6−アルキルグアニン−dnaアルキルトランスフェラーゼの突然変異体 Download PDF

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JP2007525988A
JP2007525988A JP2007501284A JP2007501284A JP2007525988A JP 2007525988 A JP2007525988 A JP 2007525988A JP 2007501284 A JP2007501284 A JP 2007501284A JP 2007501284 A JP2007501284 A JP 2007501284A JP 2007525988 A JP2007525988 A JP 2007525988A
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JP2007525988A5 (enExample
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バルニコフ,ヤン
チドリー,クリストファー
グローネマイヤー,トーマス
ハイニス,クリスティアン
ジャッカール,ユーグ
ヨハンソン,カイ
ジュイラ,アレクサンドレ
ケップラー,アントイェ
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Ecole Polytechnique Federale de Lausanne EPFL
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Ecole Polytechnique Federale de Lausanne EPFL
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Priority claimed from EP04405123.3A external-priority patent/EP1571205A1/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1003Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007Methyltransferases (general) (2.1.1.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2007501284A 2004-03-02 2005-03-01 O6−アルキルグアニン−dnaアルキルトランスフェラーゼの突然変異体 Pending JP2007525988A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04405123.3A EP1571205A1 (en) 2004-03-02 Mutants of O6-Alkylguanine-DNA Alkyltransferase
EP04405465 2004-07-22
PCT/EP2005/050899 WO2005085431A2 (en) 2004-03-02 2005-03-01 Mutants of o6-alkylguanine-dna alkyltransferase

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JP2007525988A true JP2007525988A (ja) 2007-09-13
JP2007525988A5 JP2007525988A5 (enExample) 2008-04-17

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JP2007501284A Pending JP2007525988A (ja) 2004-03-02 2005-03-01 O6−アルキルグアニン−dnaアルキルトランスフェラーゼの突然変異体

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US (2) US7888090B2 (enExample)
EP (1) EP1720981A2 (enExample)
JP (1) JP2007525988A (enExample)
WO (1) WO2005085431A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7825096B2 (en) 2004-09-08 2010-11-02 The United States Of America As Represented By The Department Of Health And Human Services O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs
EP1978093A1 (en) * 2007-04-04 2008-10-08 Ecole Polytechnique Fédérale de Lausanne (EPFL) Method of crosslinking two objects of interest
US20100209933A1 (en) * 2007-10-29 2010-08-19 Mcreynolds Larry A Methods and Compositions for Detection and Enrichment of Target Small RNAs
US20130183696A1 (en) 2010-09-15 2013-07-18 Constance Neely Wilson Methods of use and kit for measurement of lipopolysaccharide with a time resolved fluorescence based assay
US9079963B2 (en) * 2011-11-25 2015-07-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Monoclonal antibody for the detection of SNAP/CLIP tag
US9267117B2 (en) 2012-03-15 2016-02-23 New England Biolabs, Inc. Mapping cytosine modifications
US9567632B2 (en) 2013-03-19 2017-02-14 New England Biolabs, Inc. Enrichment of target sequences
WO2016003795A1 (en) 2014-07-02 2016-01-07 New England Biolabs, Inc. Universal n-glycan binding reagent
JP2017537657A (ja) 2014-12-11 2017-12-21 ニユー・イングランド・バイオレイブス・インコーポレイテツド 標的配列の濃縮
US10934533B1 (en) 2018-10-10 2021-03-02 New England Biolabs, Inc. Variant DNA polymerases having improved properties and method for improved isothermal amplification of a target DNA
US11726081B2 (en) 2019-02-15 2023-08-15 Regents Of The University Of Minnesota Methods to identify modulators of tau protein structure
US11656221B2 (en) * 2019-06-11 2023-05-23 Regents Of The University Of Minnesota Methods to identify modulators of actin-binding proteins
WO2021163559A1 (en) 2020-02-13 2021-08-19 New England Biolabs, Inc. Variant family d dna polymerases
EP4103701A1 (en) 2020-02-13 2022-12-21 New England Biolabs, Inc. Variant family d dna polymerases
WO2021183921A1 (en) 2020-03-12 2021-09-16 New England Biolabs, Inc. A rapid diagnostic test for lamp
EP4110945A2 (en) 2020-08-21 2023-01-04 New England Biolabs, Inc. A rapid diagnostic test for lamp
WO2022250676A1 (en) 2021-05-27 2022-12-01 New England Biolabs, Inc. Dnase i variants, compositions, methods, and kits
US11993792B2 (en) 2021-05-27 2024-05-28 New England Biolabs, Inc. DNase I variants, compositions, methods, and kits
AU2022396419A1 (en) 2021-11-24 2024-05-23 New England Biolabs, Inc. Double-stranded dna deaminases
WO2023197015A1 (en) 2022-04-08 2023-10-12 New England Biolabs, Inc. Compositions and analysis of dephosphorylated oligoribonucleotides
EP4658673A1 (en) 2023-02-01 2025-12-10 New England Biolabs, Inc. Duplex-specific dnases
WO2025076551A1 (en) 2023-10-05 2025-04-10 New England Biolabs, Inc. Methyl cytosine-selective deaminases and uses thereof
WO2025137453A1 (en) 2023-12-20 2025-06-26 New England Biolabs, Inc. Compositions, methods, kits, and instruments for analyzing rna structure
GB202400129D0 (en) 2024-01-04 2024-02-21 Cambridge Entpr Ltd Nucleic acid barcodes
WO2025227034A1 (en) 2024-04-26 2025-10-30 New England Biolabs, Inc. Salt active nuclease compositions and methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013487A1 (en) * 1996-09-27 1998-04-02 Maxygen, Inc. Methods for optimization of gene therapy by recursive sequence shuffling and selection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ540410A (en) * 2001-04-10 2006-06-30 Ecole Polytech Methods using O6-alkylguanine-DNA alkyltransferases
EP1546371A1 (en) 2002-10-03 2005-06-29 Ecole Polytechnique Federale De Lausanne (Epfl) Substrates for o6-alkylguanine-dna alkyltransferase
WO2004031404A1 (en) 2002-10-03 2004-04-15 Ecole Polytechnique Federale De Lausanne (Epfl) Protein labelling with o6-alkylguanine-dna alkyltransferase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998013487A1 (en) * 1996-09-27 1998-04-02 Maxygen, Inc. Methods for optimization of gene therapy by recursive sequence shuffling and selection

Also Published As

Publication number Publication date
WO2005085431A3 (en) 2005-12-08
US20110165593A1 (en) 2011-07-07
WO2005085431A2 (en) 2005-09-15
US7888090B2 (en) 2011-02-15
EP1720981A2 (en) 2006-11-15
WO2005085431A9 (en) 2006-10-12
US20070207532A1 (en) 2007-09-06

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