JP2007522243A5 - - Google Patents
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- Publication number
- JP2007522243A5 JP2007522243A5 JP2006553327A JP2006553327A JP2007522243A5 JP 2007522243 A5 JP2007522243 A5 JP 2007522243A5 JP 2006553327 A JP2006553327 A JP 2006553327A JP 2006553327 A JP2006553327 A JP 2006553327A JP 2007522243 A5 JP2007522243 A5 JP 2007522243A5
- Authority
- JP
- Japan
- Prior art keywords
- fgfr
- composition
- fgf
- sulf1
- fgf4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091008794 FGF receptors Proteins 0.000 claims 2
- 102000052178 fibroblast growth factor receptor activity proteins Human genes 0.000 claims 2
- 102100028072 Fibroblast growth factor 4 Human genes 0.000 claims 1
- 101001060274 Homo sapiens Fibroblast growth factor 4 Proteins 0.000 claims 1
- 101150048283 SULF1 gene Proteins 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- -1 modified heparin compound Chemical class 0.000 claims 1
- 230000011664 signaling Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54444904P | 2004-02-13 | 2004-02-13 | |
| PCT/US2005/004682 WO2005079390A2 (en) | 2004-02-13 | 2005-02-11 | Inhibition of fgf signaling |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007522243A JP2007522243A (ja) | 2007-08-09 |
| JP2007522243A5 true JP2007522243A5 (https=) | 2008-03-21 |
Family
ID=34886037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006553327A Pending JP2007522243A (ja) | 2004-02-13 | 2005-02-11 | Ｆｇｆシグナリングの阻害 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7968527B2 (https=) |
| EP (1) | EP1742961A4 (https=) |
| JP (1) | JP2007522243A (https=) |
| CA (1) | CA2555417A1 (https=) |
| WO (1) | WO2005079390A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200914044A (en) * | 2007-07-12 | 2009-04-01 | Daiichi Sankyo Co Ltd | Anti human Sulf1 antibody |
| WO2009011892A2 (en) * | 2007-07-18 | 2009-01-22 | Boston Biomedical Research Institute | Use of suif proteins and heparan sulfate in gdnf-dependent neural innervation and protection |
| WO2010003023A2 (en) * | 2008-07-01 | 2010-01-07 | Zacharon Pharmaceuticals, Inc. | Heparan sulfate inhibitors |
| EP2483406A2 (en) | 2009-09-30 | 2012-08-08 | President and Fellows of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-inhibiting gene products |
| JP5784296B2 (ja) * | 2010-10-01 | 2015-09-24 | 学校法人 創価大学 | 神経細胞の製造方法及び神経細胞分化促進剤 |
| KR20150123250A (ko) | 2013-03-06 | 2015-11-03 | 제넨테크, 인크. | 암 약물 내성의 치료 및 예방 방법 |
| CN107073121A (zh) | 2014-06-13 | 2017-08-18 | 基因泰克公司 | 治疗及预防癌症药物抗性的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003503313A (ja) * | 1999-06-03 | 2003-01-28 | ジェシー エル エス オウ | 細胞増殖及び細胞死を変調する方法及び組成物 |
| US7129072B1 (en) * | 1999-08-30 | 2006-10-31 | New York University | Crystal of fibroblast growth factor receptor 1 in complex with fibroblast growth factor |
| US20030147875A1 (en) * | 2000-12-27 | 2003-08-07 | Steven Rosen | Sulfatases and methods of use thereof |
| AU2002355844A1 (en) * | 2001-08-01 | 2003-02-17 | New York University | Identification of receptor and heparin binding sites in fgf4 by structure-based mutagenesis |
-
2005
- 2005-02-11 JP JP2006553327A patent/JP2007522243A/ja active Pending
- 2005-02-11 WO PCT/US2005/004682 patent/WO2005079390A2/en not_active Ceased
- 2005-02-11 CA CA002555417A patent/CA2555417A1/en not_active Abandoned
- 2005-02-11 EP EP05713533A patent/EP1742961A4/en not_active Withdrawn
- 2005-02-11 US US11/057,390 patent/US7968527B2/en not_active Expired - Fee Related
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