JP2007517636A5 - - Google Patents
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- Publication number
- JP2007517636A5 JP2007517636A5 JP2006549651A JP2006549651A JP2007517636A5 JP 2007517636 A5 JP2007517636 A5 JP 2007517636A5 JP 2006549651 A JP2006549651 A JP 2006549651A JP 2006549651 A JP2006549651 A JP 2006549651A JP 2007517636 A5 JP2007517636 A5 JP 2007517636A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- mouthpiece
- dose
- cartridge
- ribbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 26
- 229940079593 drug Drugs 0.000 claims 24
- 239000000843 powder Substances 0.000 claims 6
- 210000000214 mouth Anatomy 0.000 claims 5
- 238000012377 drug delivery Methods 0.000 claims 4
- 239000013583 drug formulation Substances 0.000 claims 4
- 238000010304 firing Methods 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 230000001960 triggered effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53726604P | 2004-01-16 | 2004-01-16 | |
| PCT/US2005/001351 WO2005072803A1 (en) | 2004-01-16 | 2005-01-18 | Sublingual drug delivery device |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007517636A JP2007517636A (ja) | 2007-07-05 |
| JP2007517636A5 true JP2007517636A5 (https=) | 2007-08-16 |
| JP4601627B2 JP4601627B2 (ja) | 2010-12-22 |
Family
ID=34825920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006549651A Expired - Fee Related JP4601627B2 (ja) | 2004-01-16 | 2005-01-18 | 舌下薬物送達デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7658721B2 (https=) |
| EP (1) | EP1711220A1 (https=) |
| JP (1) | JP4601627B2 (https=) |
| AU (1) | AU2005209199B2 (https=) |
| CA (1) | CA2553392A1 (https=) |
| WO (1) | WO2005072803A1 (https=) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US7080644B2 (en) * | 2000-06-28 | 2006-07-25 | Microdose Technologies, Inc. | Packaging and delivery of pharmaceuticals and drugs |
| WO2003080149A2 (en) | 2002-03-20 | 2003-10-02 | Mannkind Corporation | Inhalation apparatus |
| MXPA06009516A (es) | 2004-02-24 | 2007-03-26 | Microdose Technologies Inc | Inhalador con sensor de flujo direccional. |
| PL1786784T3 (pl) | 2004-08-20 | 2011-04-29 | Mannkind Corp | Kataliza syntezy diketopiperazyn |
| KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
| US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
| US8357114B2 (en) | 2006-01-06 | 2013-01-22 | Acelrx Pharmaceuticals, Inc. | Drug dispensing device with flexible push rod |
| WO2008085764A1 (en) * | 2007-01-05 | 2008-07-17 | Acelrx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
| US8252329B2 (en) | 2007-01-05 | 2012-08-28 | Acelrx Pharmaceuticals, Inc. | Bioadhesive drug formulations for oral transmucosal delivery |
| US8202535B2 (en) | 2006-01-06 | 2012-06-19 | Acelrx Pharmaceuticals, Inc. | Small-volume oral transmucosal dosage forms |
| US8865743B2 (en) | 2006-01-06 | 2014-10-21 | Acelrx Pharmaceuticals, Inc. | Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain |
| IN2015DN00888A (https=) | 2006-02-22 | 2015-07-10 | Mannkind Corp | |
| ATE497397T1 (de) * | 2006-07-15 | 2011-02-15 | Novo Nordisk As | Medizinisches abgabeystem mit drehbarem verschlüsselungselement |
| EP2121086B2 (en) | 2006-11-21 | 2015-12-23 | Novo Nordisk A/S | Medical delivery system comprising locking ring with l-shaped grooves |
| US8415390B2 (en) | 2008-05-30 | 2013-04-09 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| US9119777B2 (en) | 2008-05-30 | 2015-09-01 | Microdose Therapeutx, Inc. | Methods and compositions for administration of oxybutynin |
| WO2009007068A1 (en) | 2007-07-06 | 2009-01-15 | Boehringer Ingelheim International Gmbh | Inhaler |
| US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
| DE102007056263A1 (de) | 2007-11-22 | 2009-05-28 | Siegfried Generics International Ag | Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz |
| US8371294B2 (en) * | 2008-02-29 | 2013-02-12 | Microdose Therapeutx, Inc. | Method and apparatus for driving a transducer of an inhalation device |
| ES2929343T3 (es) | 2008-06-13 | 2022-11-28 | Mannkind Corp | Inhalador de polvo seco accionado por aspiración para la administración de fármacos |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| KR101628410B1 (ko) | 2008-06-20 | 2016-06-08 | 맨카인드 코포레이션 | 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법 |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| EP2399638B1 (en) | 2009-02-23 | 2014-01-22 | Japan Tobacco, Inc. | Non-heating type flavor inhaler |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| US8548623B2 (en) | 2009-03-18 | 2013-10-01 | Acelrx Pharmaceuticals, Inc. | Storage and dispensing devices for administration of oral transmucosal dosage forms |
| FR2943538B1 (fr) | 2009-03-27 | 2011-05-20 | Adocia | Formulation a action rapide d'insuline recombinante humaine |
| US9018190B2 (en) | 2009-03-27 | 2015-04-28 | Adocia | Functionalized oligosaccharides |
| US20100286587A1 (en) * | 2009-05-07 | 2010-11-11 | Yossi Gross | Sublingual electrical drug delivery |
| US8985101B2 (en) | 2009-05-21 | 2015-03-24 | Microdose Therapeutx, Inc. | Method and device for clamping a blister within a dry powder inhaler |
| AU2010249402B2 (en) * | 2009-05-21 | 2014-08-21 | Microdose Therapeutx, Inc. | Rotary cassette system for dry powder inhaler |
| CN104721825B (zh) | 2009-06-12 | 2019-04-12 | 曼金德公司 | 具有确定比表面积的二酮哌嗪颗粒 |
| US20110000481A1 (en) * | 2009-07-01 | 2011-01-06 | Anand Gumaste | Nebulizer for infants and respiratory compromised patients |
| WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| CN105381524A (zh) | 2010-01-05 | 2016-03-09 | 微剂量治疗技术公司 | 吸入设备和方法 |
| IL223742A (en) | 2010-06-21 | 2016-06-30 | Mannkind Corp | A dry powder inhaler and preparation for it |
| AU2012236150B2 (en) | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| ITBO20110289A1 (it) * | 2011-05-20 | 2012-11-21 | Health Robotics Srl | Scatola di contenimento di una sacca per prodotti farmaceutici |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| US20130231281A1 (en) | 2011-11-02 | 2013-09-05 | Adocia | Rapid acting insulin formulation comprising an oligosaccharide |
| CN104619369B (zh) | 2012-07-12 | 2018-01-30 | 曼金德公司 | 干粉药物输送系统和方法 |
| US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
| CN104902922B (zh) | 2012-11-13 | 2017-12-12 | 阿道恰公司 | 包含经取代阴离子化合物的速效胰岛素制剂 |
| AU2014228415B2 (en) | 2013-03-15 | 2018-08-09 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US9795678B2 (en) | 2014-05-14 | 2017-10-24 | Adocia | Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound |
| FR3020947B1 (fr) | 2014-05-14 | 2018-08-31 | Adocia | Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| NZ732808A (en) | 2014-12-23 | 2021-12-24 | Acelrx Pharmaceuticals Inc | Systems, devices and methods for dispensing oral transmucosal dosage forms |
| CN113143769A (zh) | 2015-10-30 | 2021-07-23 | 阿塞尔Rx制药有限公司 | 用于分配口腔经粘膜剂型的设备和方法 |
| FR3043557B1 (fr) | 2015-11-16 | 2019-05-31 | Adocia | Composition a action rapide d'insuline comprenant un citrate substitue |
| US10238821B2 (en) | 2016-10-11 | 2019-03-26 | Microdose Therapeutx, Inc. | Inhaler and methods of use thereof |
| CN110621259B (zh) * | 2017-03-09 | 2021-11-02 | 马辛宾科夫斯基N-实验室 | 口腔内扫描装置、这种装置的操作方法以及扫描器系统 |
| CN112237666B (zh) * | 2019-07-17 | 2022-06-17 | 东莞市爱的仕机电设备有限公司 | 一种雾化器及雾化器用的舌下喷嘴 |
| US11607508B1 (en) | 2020-12-23 | 2023-03-21 | Stat Capsule Inc. | Device for sublingual application of a therapeutic dose of medication in fractions |
| US20240277950A1 (en) * | 2023-02-20 | 2024-08-22 | Win Htay Fang | Reliable compact inhalation device for asthma and chronic obstructive pulmonary disease |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE247684C (https=) | ||||
| GB1479283A (en) * | 1973-07-23 | 1977-07-13 | Bespak Industries Ltd | Inhaler for powdered medicament |
| US4211769A (en) * | 1977-08-24 | 1980-07-08 | Takeda Chemical Industries, Ltd. | Preparations for vaginal administration |
| US4196196A (en) * | 1978-06-19 | 1980-04-01 | Tiholiz Ivan C | Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states |
| DK147437A (en) | 1980-02-11 | 1900-01-01 | Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof | |
| DE3942145A1 (de) | 1989-12-20 | 1991-06-27 | Boehringer Mannheim Gmbh | T-pa-solubilisierung |
| AU653026B2 (en) * | 1991-06-07 | 1994-09-15 | Teikoku Seiyaku Kabushiki Kaisha | Physiologically active polypeptide-containing pharmaceutical composition |
| DE4142238A1 (de) | 1991-12-20 | 1993-06-24 | Boehringer Ingelheim Kg | Pulverinhalator mit pulvertraeger aus regelmaessigen mikrostrukturen |
| US5819726A (en) * | 1993-01-29 | 1998-10-13 | Aradigm Corporation | Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease |
| US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5441060A (en) * | 1993-02-08 | 1995-08-15 | Duke University | Dry powder delivery system |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| WO1996010996A1 (en) | 1993-07-21 | 1996-04-18 | The University Of Kentucky Research Foundation | A multicompartment hard capsule with control release properties |
| US5534488A (en) * | 1993-08-13 | 1996-07-09 | Eli Lilly And Company | Insulin formulation |
| US5388572A (en) | 1993-10-26 | 1995-02-14 | Tenax Corporation (A Connecticut Corp.) | Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same |
| US5461031A (en) * | 1994-06-16 | 1995-10-24 | Eli Lilly And Company | Monomeric insulin analog formulations |
| US5474978A (en) * | 1994-06-16 | 1995-12-12 | Eli Lilly And Company | Insulin analog formulations |
| NZ293163A (en) * | 1994-09-21 | 1998-09-24 | Inhale Therapeutic Syst | Inhalation medicament disperser, aerosol from high pressure gas entrainment of fluidised powder drawn from receptacle feed tube |
| US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
| US5849322A (en) * | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
| US5912014A (en) | 1996-03-15 | 1999-06-15 | Unigene Laboratories, Inc. | Oral salmon calcitonin pharmaceutical products |
| AUPO066096A0 (en) | 1996-06-26 | 1996-07-18 | Peptide Delivery Systems Pty Ltd | Oral delivery of peptides |
| DE19647947A1 (de) * | 1996-11-20 | 1998-05-28 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| JP2001518916A (ja) | 1997-03-20 | 2001-10-16 | ノボ ノルディスク アクティーゼルスカブ | 結晶インスリンを含有する肺投与のための治療用粉末調合物 |
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| US6310038B1 (en) * | 1997-03-20 | 2001-10-30 | Novo Nordisk A/S | Pulmonary insulin crystals |
| US5898028A (en) * | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
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| CN1141974C (zh) * | 2000-06-07 | 2004-03-17 | 张昊 | 结肠定位释放的口服生物制剂 |
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| JP4943838B2 (ja) * | 2003-04-09 | 2012-05-30 | ネクター セラピューティクス | 空気入口シールドを備えたエアゾール化装置 |
| US20050203001A1 (en) * | 2004-03-05 | 2005-09-15 | Emisphere Technologies, Inc. | Oral insulin therapies and protocol |
| US7192919B2 (en) * | 2004-01-07 | 2007-03-20 | Stelios Tzannis | Sustained release compositions for delivery of pharmaceutical proteins |
| JP2009512709A (ja) | 2005-10-20 | 2009-03-26 | エムディーアールエヌエー,インコーポレイテッド | 速効型インスリンの経鼻投与 |
| US8093207B2 (en) * | 2005-12-09 | 2012-01-10 | Unigene Laboratories, Inc. | Fast-acting oral peptide pharmaceutical products |
-
2005
- 2005-01-18 US US11/037,737 patent/US7658721B2/en not_active Expired - Fee Related
- 2005-01-18 WO PCT/US2005/001351 patent/WO2005072803A1/en not_active Ceased
- 2005-01-18 EP EP05705773A patent/EP1711220A1/en not_active Withdrawn
- 2005-01-18 AU AU2005209199A patent/AU2005209199B2/en not_active Ceased
- 2005-01-18 CA CA002553392A patent/CA2553392A1/en not_active Abandoned
- 2005-01-18 JP JP2006549651A patent/JP4601627B2/ja not_active Expired - Fee Related
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