JP2007516192A - 有機ケイ素化合物およびその使用 - Google Patents

有機ケイ素化合物およびその使用 Download PDF

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Publication number
JP2007516192A
JP2007516192A JP2006518321A JP2006518321A JP2007516192A JP 2007516192 A JP2007516192 A JP 2007516192A JP 2006518321 A JP2006518321 A JP 2006518321A JP 2006518321 A JP2006518321 A JP 2006518321A JP 2007516192 A JP2007516192 A JP 2007516192A
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JP
Japan
Prior art keywords
carboxamide
furan
yloxy
sila
pyrimidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006518321A
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English (en)
Japanese (ja)
Inventor
デイヴィッド・ジョン・ミラー
グラハム・アンドリュー・ショーウェル
リチャード・コンロイ
イェエルゲン・ダイス
ラインホルト・タッケ
ダヴィッド・テッベ
Original Assignee
パラダイム・セラピューティクス・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0316090A external-priority patent/GB0316090D0/en
Priority claimed from GB0402903A external-priority patent/GB0402903D0/en
Priority claimed from GB0411071A external-priority patent/GB0411071D0/en
Application filed by パラダイム・セラピューティクス・リミテッド filed Critical パラダイム・セラピューティクス・リミテッド
Publication of JP2007516192A publication Critical patent/JP2007516192A/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicon Polymers (AREA)
JP2006518321A 2003-07-09 2004-06-18 有機ケイ素化合物およびその使用 Pending JP2007516192A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0316090A GB0316090D0 (en) 2003-07-09 2003-07-09 Compounds and their use
GB0402903A GB0402903D0 (en) 2004-02-10 2004-02-10 Compounds and their use
GB0411071A GB0411071D0 (en) 2004-05-18 2004-05-18 Compounds and their use
PCT/GB2004/002622 WO2005005443A1 (en) 2003-07-09 2004-06-18 Organosilicon compounds and their use

Publications (1)

Publication Number Publication Date
JP2007516192A true JP2007516192A (ja) 2007-06-21

Family

ID=34068755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006518321A Pending JP2007516192A (ja) 2003-07-09 2004-06-18 有機ケイ素化合物およびその使用

Country Status (13)

Country Link
US (1) US20070111967A1 (es)
EP (1) EP1648906B1 (es)
JP (1) JP2007516192A (es)
KR (1) KR20060029282A (es)
AT (1) ATE374778T1 (es)
AU (1) AU2004255913B2 (es)
BR (1) BRPI0412360A (es)
CA (1) CA2531512A1 (es)
DE (1) DE602004009313T2 (es)
DK (1) DK1648906T3 (es)
ES (1) ES2293293T3 (es)
MX (1) MXPA06000371A (es)
WO (1) WO2005005443A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015187542A1 (en) * 2014-06-02 2015-12-10 Chdi Foundation Inc. Histone deacetylase inhibitors and compositions and methods of use thereof
AU2015308987B2 (en) 2014-08-26 2021-02-18 Betanien Hospital Methods, agents and compositions for treatment of inflammatory conditions
EP3765459A1 (en) 2018-03-13 2021-01-20 Shire Human Genetic Therapies, Inc. Substituted imidazopyridines as inhibitors of plasma kallikrein and uses thereof
EP4031547B1 (en) 2019-09-18 2024-07-17 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof
EP4031245A1 (en) 2019-09-18 2022-07-27 Takeda Pharmaceutical Company Limited Heteroaryl plasma kallikrein inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0103622A3 (en) * 1998-08-20 2003-01-28 Agouron Pharmaceuticals Inc La Non-peptide gnrh agents, methods and intermediates for their preparation and medicaments containing them
JP2005538064A (ja) * 2002-06-13 2005-12-15 ファイザー・インク 非ペプチドGnRH剤、医薬組成物、およびそれらの使用方法
CA2507532A1 (en) * 2002-11-20 2004-06-03 Paradigm Therapeutics Ltd. Heterocyclic silicon compounds and their use in the treatment of diseases or conditions associated with gnrh (gonadotropin-releasing hormone)

Also Published As

Publication number Publication date
WO2005005443A1 (en) 2005-01-20
CA2531512A1 (en) 2005-01-20
DE602004009313D1 (de) 2007-11-15
EP1648906A1 (en) 2006-04-26
ATE374778T1 (de) 2007-10-15
KR20060029282A (ko) 2006-04-05
EP1648906B1 (en) 2007-10-03
BRPI0412360A (pt) 2006-09-05
US20070111967A1 (en) 2007-05-17
MXPA06000371A (es) 2006-03-28
DK1648906T3 (da) 2008-02-04
AU2004255913A1 (en) 2005-01-20
DE602004009313T2 (de) 2008-01-10
ES2293293T3 (es) 2008-03-16
AU2004255913B2 (en) 2007-10-11

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