JP2007513873A5 - - Google Patents
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- Publication number
- JP2007513873A5 JP2007513873A5 JP2006536183A JP2006536183A JP2007513873A5 JP 2007513873 A5 JP2007513873 A5 JP 2007513873A5 JP 2006536183 A JP2006536183 A JP 2006536183A JP 2006536183 A JP2006536183 A JP 2006536183A JP 2007513873 A5 JP2007513873 A5 JP 2007513873A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- agent
- antibody
- expression
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 28
- 102000004196 processed proteins & peptides Human genes 0.000 claims 28
- 108090000765 processed proteins & peptides Proteins 0.000 claims 28
- 239000003795 chemical substances by application Substances 0.000 claims 17
- 238000000034 method Methods 0.000 claims 14
- 102100035350 CUB domain-containing protein 1 Human genes 0.000 claims 13
- 101000737742 Homo sapiens CUB domain-containing protein 1 Proteins 0.000 claims 13
- 230000000694 effects Effects 0.000 claims 11
- 206010033128 Ovarian cancer Diseases 0.000 claims 9
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 239000003153 chemical reaction reagent Substances 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 239000012634 fragment Substances 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 4
- 239000003183 carcinogenic agent Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000012216 screening Methods 0.000 claims 3
- 230000001225 therapeutic effect Effects 0.000 claims 3
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 230000003013 cytotoxicity Effects 0.000 claims 2
- 231100000135 cytotoxicity Toxicity 0.000 claims 2
- 238000012217 deletion Methods 0.000 claims 2
- 230000037430 deletion Effects 0.000 claims 2
- 239000012636 effector Substances 0.000 claims 2
- 238000003780 insertion Methods 0.000 claims 2
- 230000037431 insertion Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 230000004075 alteration Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 238000012360 testing method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0324656.8 | 2003-10-22 | ||
| GB0324656A GB0324656D0 (en) | 2003-10-22 | 2003-10-22 | A protein involved in ovarian cancer |
| PCT/GB2004/004502 WO2005042102A1 (en) | 2003-10-22 | 2004-10-22 | A protein involved in ovarian cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007513873A JP2007513873A (ja) | 2007-05-31 |
| JP2007513873A5 true JP2007513873A5 (enExample) | 2007-10-18 |
| JP4764344B2 JP4764344B2 (ja) | 2011-08-31 |
Family
ID=29595617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006536183A Expired - Fee Related JP4764344B2 (ja) | 2003-10-22 | 2004-10-22 | 卵巣癌に関与するタンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20070009543A1 (enExample) |
| EP (1) | EP1677875B1 (enExample) |
| JP (1) | JP4764344B2 (enExample) |
| AT (1) | ATE470478T1 (enExample) |
| AU (1) | AU2004285339B2 (enExample) |
| CA (1) | CA2541846A1 (enExample) |
| DE (1) | DE602004027647D1 (enExample) |
| ES (1) | ES2347249T3 (enExample) |
| GB (1) | GB0324656D0 (enExample) |
| PL (1) | PL1677875T3 (enExample) |
| WO (1) | WO2005042102A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080008719A1 (en) * | 2004-07-10 | 2008-01-10 | Bowdish Katherine S | Methods and compositions for the treatment of prostate cancer |
| AU2007210124A1 (en) * | 2006-01-26 | 2007-08-09 | The Trustees Of The University Of Pennsylvania | Tumor vasculature markers and methods of use thereof |
| US20130136689A1 (en) * | 2007-06-05 | 2013-05-30 | Christian Rohlff | Proteins |
| US8664358B2 (en) | 2007-06-29 | 2014-03-04 | Vermillion, Inc. | Predictive markers for ovarian cancer |
| TWI412375B (zh) | 2009-08-28 | 2013-10-21 | Roche Glycart Ag | 人類化抗ｃｄｃｐ１抗體 |
| TW201113037A (en) | 2009-08-28 | 2011-04-16 | Hoffmann La Roche | Antibodies against CDCP1 for the treatment of cancer |
| US9312572B2 (en) | 2013-03-13 | 2016-04-12 | Fluidic, Inc. | Synergistic additives for electrochemical cells with electrodeposited fuel |
| WO2015082446A1 (en) | 2013-12-02 | 2015-06-11 | F. Hoffmann-La Roche Ag | Treatment of cancer using an anti-cdcp1 antibody and a taxane |
| CN110234348B (zh) | 2016-12-16 | 2024-06-25 | 蓝鳍生物医药公司 | 抗-含cub结构域蛋白1(cdcp1)抗体、抗体药物缀合物及其使用方法 |
| US11424484B2 (en) | 2019-01-24 | 2022-08-23 | Octet Scientific, Inc. | Zinc battery electrolyte additive |
| AU2020377402A1 (en) * | 2019-11-06 | 2022-06-23 | Commonwealth Scientific And Industrial Research Organisation | Binding proteins to CUB domain-containing protein (CDCP1) |
| AU2020413304B2 (en) | 2019-12-27 | 2025-07-17 | Chiome Bioscience Inc. | Anti-CDCP1 antibody |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000006698A1 (en) | 1998-07-30 | 2000-02-10 | Human Genome Sciences, Inc. | 98 human secreted proteins |
| US7442776B2 (en) * | 1999-10-08 | 2008-10-28 | Young David S F | Cancerous disease modifying antibodies |
| US20020142003A1 (en) * | 2000-07-07 | 2002-10-03 | Norbert Schweifer | Tumor-associated antigen (B345) |
| EP1301533A1 (de) | 2000-07-07 | 2003-04-16 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Tumorassoziiertes antigen (b345), gekennzeichnet durch eine aminosäuresequenz wie in seq. id. no. 4 |
| US6783969B1 (en) | 2001-03-05 | 2004-08-31 | Nuvelo, Inc. | Cathepsin V-like polypeptides |
| AU2004213568A1 (en) * | 2003-02-19 | 2004-09-02 | Novartis Ag | Glycoprotein antigen SIMA135 expressed in metastatic human tumor cells |
-
2003
- 2003-10-22 GB GB0324656A patent/GB0324656D0/en not_active Ceased
-
2004
- 2004-10-22 CA CA 2541846 patent/CA2541846A1/en not_active Abandoned
- 2004-10-22 AT AT04769011T patent/ATE470478T1/de active
- 2004-10-22 JP JP2006536183A patent/JP4764344B2/ja not_active Expired - Fee Related
- 2004-10-22 US US10/575,311 patent/US20070009543A1/en not_active Abandoned
- 2004-10-22 PL PL04769011T patent/PL1677875T3/pl unknown
- 2004-10-22 AU AU2004285339A patent/AU2004285339B2/en not_active Ceased
- 2004-10-22 DE DE200460027647 patent/DE602004027647D1/de not_active Expired - Lifetime
- 2004-10-22 ES ES04769011T patent/ES2347249T3/es not_active Expired - Lifetime
- 2004-10-22 EP EP20040769011 patent/EP1677875B1/en not_active Revoked
- 2004-10-22 WO PCT/GB2004/004502 patent/WO2005042102A1/en not_active Ceased
-
2009
- 2009-10-14 US US12/587,870 patent/US8263071B2/en not_active Expired - Fee Related
-
2012
- 2012-08-03 US US13/566,011 patent/US9120860B2/en not_active Expired - Fee Related
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