JP2007512910A5 - - Google Patents
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- Publication number
- JP2007512910A5 JP2007512910A5 JP2006542715A JP2006542715A JP2007512910A5 JP 2007512910 A5 JP2007512910 A5 JP 2007512910A5 JP 2006542715 A JP2006542715 A JP 2006542715A JP 2006542715 A JP2006542715 A JP 2006542715A JP 2007512910 A5 JP2007512910 A5 JP 2007512910A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- magnetic
- kit
- cells
- magnetic field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005291 magnetic effect Effects 0.000 claims description 374
- 239000007788 liquid Substances 0.000 claims description 90
- 238000001727 in vivo Methods 0.000 claims description 78
- 238000000576 coating method Methods 0.000 claims description 45
- 239000011248 coating agent Substances 0.000 claims description 40
- 239000000696 magnetic material Substances 0.000 claims description 40
- 210000004204 blood vessel Anatomy 0.000 claims description 32
- 239000012530 fluid Substances 0.000 claims description 22
- 230000000717 retained effect Effects 0.000 claims description 19
- 230000002792 vascular Effects 0.000 claims description 16
- 238000000338 in vitro Methods 0.000 claims description 14
- 229910052751 metal Inorganic materials 0.000 claims description 12
- 239000002184 metal Substances 0.000 claims description 12
- 150000002739 metals Chemical class 0.000 claims description 10
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- 229910001092 metal group alloy Inorganic materials 0.000 claims description 8
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- 238000000034 method Methods 0.000 description 83
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- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 2
- KPLQYGBQNPPQGA-UHFFFAOYSA-N cobalt samarium Chemical compound [Co].[Sm] KPLQYGBQNPPQGA-UHFFFAOYSA-N 0.000 description 2
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- 229910052742 iron Inorganic materials 0.000 description 2
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 2
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- 210000004072 lung Anatomy 0.000 description 2
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- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical group NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 description 1
- 206010003226 Arteriovenous fistula Diseases 0.000 description 1
- 208000032170 Congenital Abnormalities Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 229910052692 Dysprosium Inorganic materials 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 229930182816 L-glutamine Natural products 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- HHZHOPJRSHTPOP-UHFFFAOYSA-N [O--].[O--].[Fe++].[Sr++] Chemical compound [O--].[O--].[Fe++].[Sr++] HHZHOPJRSHTPOP-UHFFFAOYSA-N 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
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- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000009830 antibody antigen interaction Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
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- 230000004071 biological effect Effects 0.000 description 1
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- 229920001400 block copolymer Polymers 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- UTKFUXQDBUMJSX-UHFFFAOYSA-N boron neodymium Chemical compound [B].[Nd] UTKFUXQDBUMJSX-UHFFFAOYSA-N 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
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- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- KBQHZAAAGSGFKK-UHFFFAOYSA-N dysprosium atom Chemical compound [Dy] KBQHZAAAGSGFKK-UHFFFAOYSA-N 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
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- 208000019622 heart disease Diseases 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 102000006495 integrins Human genes 0.000 description 1
- 108010044426 integrins Proteins 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 102000006240 membrane receptors Human genes 0.000 description 1
- 108020004084 membrane receptors Proteins 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
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- 238000012544 monitoring process Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 238000005949 ozonolysis reaction Methods 0.000 description 1
- 210000000277 pancreatic duct Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000729 poly(L-lysine) polymer Polymers 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000006557 surface reaction Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003573 thiols Chemical group 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52652203P | 2003-12-03 | 2003-12-03 | |
| US60/526,522 | 2003-12-03 | ||
| PCT/US2004/040242 WO2005056073A2 (en) | 2003-12-03 | 2004-12-02 | Kits, apparatus and methods for magnetically coating medical devices with living cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007512910A JP2007512910A (ja) | 2007-05-24 |
| JP2007512910A5 true JP2007512910A5 (enExample) | 2008-01-31 |
| JP4913602B2 JP4913602B2 (ja) | 2012-04-11 |
Family
ID=34676624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006542715A Expired - Fee Related JP4913602B2 (ja) | 2003-12-03 | 2004-12-02 | 医用デバイスに生細胞を磁気的にコーティングするためのキット、装置、および方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1699501B1 (enExample) |
| JP (1) | JP4913602B2 (enExample) |
| CN (1) | CN100556469C (enExample) |
| AT (1) | ATE544477T1 (enExample) |
| WO (1) | WO2005056073A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090118817A1 (en) | 2005-06-16 | 2009-05-07 | Mayo Foundation For Medical Education And Research | Magnetic Medical Apparatus, Kits, and Methods |
| US8465453B2 (en) | 2003-12-03 | 2013-06-18 | Mayo Foundation For Medical Education And Research | Kits, apparatus and methods for magnetically coating medical devices with living cells |
| WO2005089507A2 (en) * | 2004-03-19 | 2005-09-29 | Moldovan Nicanor I | System for providing implant compatibility with recipient |
| WO2008057565A2 (en) * | 2006-11-06 | 2008-05-15 | Howmedica Osteonics Corp. | Artificial cushion joints and methods of making the same |
| CN101756754B (zh) * | 2009-11-05 | 2012-01-11 | 中国人民解放军第四军医大学第一附属医院 | 磁性封堵器的制备方法 |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| GB201116879D0 (en) | 2011-09-30 | 2011-11-16 | Magnus Stent Ic | Endoprosthesis |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| CN103565564B (zh) * | 2012-08-02 | 2017-02-22 | 上海微创医疗器械（集团）有限公司 | 一种含磁性底层的双面涂层药物洗脱支架及其制作方法 |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| CN104174110B (zh) * | 2013-05-23 | 2017-06-27 | 微创心脉医疗科技（上海）有限公司 | 一种药物球囊及其制备方法 |
| WO2017100927A1 (en) | 2015-12-15 | 2017-06-22 | Neovasc Tiara Inc. | Transseptal delivery system |
| US10433952B2 (en) | 2016-01-29 | 2019-10-08 | Neovasc Tiara Inc. | Prosthetic valve for avoiding obstruction of outflow |
| US10327667B2 (en) * | 2016-05-13 | 2019-06-25 | Becton, Dickinson And Company | Electro-magnetic needle catheter insertion system |
| CN113893064A (zh) | 2016-11-21 | 2022-01-07 | 内奥瓦斯克迪亚拉公司 | 用于快速收回经导管心脏瓣膜递送系统的方法和系统 |
| US10765835B2 (en) * | 2017-04-05 | 2020-09-08 | Becton, Dickinson And Company | Needle magnetizer |
| US10856984B2 (en) | 2017-08-25 | 2020-12-08 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| AU2019374743B2 (en) | 2018-11-08 | 2022-03-03 | Neovasc Tiara Inc. | Ventricular deployment of a transcatheter mitral valve prosthesis |
| US11998447B2 (en) | 2019-03-08 | 2024-06-04 | Neovasc Tiara Inc. | Retrievable prosthesis delivery system |
| EP3946163B1 (en) | 2019-04-01 | 2025-08-20 | Neovasc Tiara Inc. | Controllably deployable prosthetic valve |
| US11491006B2 (en) | 2019-04-10 | 2022-11-08 | Neovasc Tiara Inc. | Prosthetic valve with natural blood flow |
| CN114025813B (zh) | 2019-05-20 | 2024-05-14 | 内奥瓦斯克迪亚拉公司 | 具有止血机构的引入器 |
| US11311376B2 (en) | 2019-06-20 | 2022-04-26 | Neovase Tiara Inc. | Low profile prosthetic mitral valve |
| CN114762753B (zh) * | 2021-01-13 | 2025-04-01 | 江千里 | 磁导向装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0382465A (ja) * | 1989-08-25 | 1991-04-08 | Kanegafuchi Chem Ind Co Ltd | 磁性を有する人工血管 |
| CA2074304C (en) * | 1991-08-02 | 1996-11-26 | Cyril J. Schweich, Jr. | Drug delivery catheter |
| IL119189A0 (en) * | 1996-09-03 | 1996-12-05 | Lev Shlomo | Annulus catheter |
| US6129704A (en) * | 1997-06-12 | 2000-10-10 | Schneider (Usa) Inc. | Perfusion balloon catheter having a magnetically driven impeller |
| US6689119B1 (en) * | 2000-06-02 | 2004-02-10 | Scimed Life Systems, Inc. | Self-aligning medical device |
| ATE387167T1 (de) * | 2001-01-19 | 2008-03-15 | Boston Scient Ltd | Vorrichtung zum einbringen einer abzweigenden prothese |
| US6673104B2 (en) * | 2001-03-15 | 2004-01-06 | Scimed Life Systems, Inc. | Magnetic stent |
| AU2002359340A1 (en) * | 2001-10-31 | 2003-05-12 | Ventrigraft Inc | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo |
-
2004
- 2004-12-02 EP EP04812694A patent/EP1699501B1/en not_active Expired - Lifetime
- 2004-12-02 CN CNB2004800362295A patent/CN100556469C/zh not_active Expired - Fee Related
- 2004-12-02 AT AT04812694T patent/ATE544477T1/de active
- 2004-12-02 WO PCT/US2004/040242 patent/WO2005056073A2/en not_active Ceased
- 2004-12-02 JP JP2006542715A patent/JP4913602B2/ja not_active Expired - Fee Related
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