JP2007512910A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007512910A5 JP2007512910A5 JP2006542715A JP2006542715A JP2007512910A5 JP 2007512910 A5 JP2007512910 A5 JP 2007512910A5 JP 2006542715 A JP2006542715 A JP 2006542715A JP 2006542715 A JP2006542715 A JP 2006542715A JP 2007512910 A5 JP2007512910 A5 JP 2007512910A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- magnetic
- kit
- cells
- magnetic field
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005291 magnetic effect Effects 0.000 claims description 374
- 239000007788 liquid Substances 0.000 claims description 90
- 238000001727 in vivo Methods 0.000 claims description 78
- 238000000576 coating method Methods 0.000 claims description 45
- 239000011248 coating agent Substances 0.000 claims description 40
- 239000000696 magnetic material Substances 0.000 claims description 40
- 210000004204 blood vessel Anatomy 0.000 claims description 32
- 239000012530 fluid Substances 0.000 claims description 22
- 230000000717 retained effect Effects 0.000 claims description 19
- 230000002792 vascular Effects 0.000 claims description 16
- 238000000338 in vitro Methods 0.000 claims description 14
- 229910052751 metal Inorganic materials 0.000 claims description 12
- 239000002184 metal Substances 0.000 claims description 12
- 150000002739 metals Chemical class 0.000 claims description 10
- 210000003709 heart valve Anatomy 0.000 claims description 9
- 229910001092 metal group alloy Inorganic materials 0.000 claims description 8
- 230000002861 ventricular Effects 0.000 claims description 8
- 238000003780 insertion Methods 0.000 claims description 5
- 230000037431 insertion Effects 0.000 claims description 5
- 239000011230 binding agent Substances 0.000 claims description 4
- 210000004027 cell Anatomy 0.000 description 204
- 238000000034 method Methods 0.000 description 83
- 239000006249 magnetic particle Substances 0.000 description 21
- 239000000463 material Substances 0.000 description 20
- 239000002245 particle Substances 0.000 description 19
- 210000002889 endothelial cell Anatomy 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 12
- 239000008280 blood Substances 0.000 description 12
- 230000008901 benefit Effects 0.000 description 10
- 238000002513 implantation Methods 0.000 description 10
- 239000003446 ligand Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- 230000027455 binding Effects 0.000 description 9
- 230000005347 demagnetization Effects 0.000 description 9
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 8
- 230000005415 magnetization Effects 0.000 description 8
- 239000012528 membrane Substances 0.000 description 8
- 108090000623 proteins and genes Proteins 0.000 description 8
- 210000000170 cell membrane Anatomy 0.000 description 7
- 229920000642 polymer Polymers 0.000 description 7
- 235000018102 proteins Nutrition 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 230000014759 maintenance of location Effects 0.000 description 5
- 239000011159 matrix material Substances 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 229910000859 α-Fe Inorganic materials 0.000 description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000005684 electric field Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229910052759 nickel Inorganic materials 0.000 description 4
- 238000010899 nucleation Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000011144 upstream manufacturing Methods 0.000 description 4
- 102000016359 Fibronectins Human genes 0.000 description 3
- 108010067306 Fibronectins Proteins 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 239000012620 biological material Substances 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 238000007385 chemical modification Methods 0.000 description 3
- 239000007943 implant Substances 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 238000002715 modification method Methods 0.000 description 3
- 229910001000 nickel titanium Inorganic materials 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 229910000938 samarium–cobalt magnet Inorganic materials 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 206010002329 Aneurysm Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 206010072810 Vascular wall hypertrophy Diseases 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 229910045601 alloy Inorganic materials 0.000 description 2
- 239000000956 alloy Substances 0.000 description 2
- 150000001412 amines Chemical group 0.000 description 2
- 230000002785 anti-thrombosis Effects 0.000 description 2
- -1 antibodies Proteins 0.000 description 2
- 239000003146 anticoagulant agent Substances 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 239000002473 artificial blood Substances 0.000 description 2
- 210000000941 bile Anatomy 0.000 description 2
- 210000000013 bile duct Anatomy 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 2
- 239000010941 cobalt Substances 0.000 description 2
- 229910017052 cobalt Inorganic materials 0.000 description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 2
- KPLQYGBQNPPQGA-UHFFFAOYSA-N cobalt samarium Chemical compound [Co].[Sm] KPLQYGBQNPPQGA-UHFFFAOYSA-N 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 238000004520 electroporation Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000005294 ferromagnetic effect Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 230000004927 fusion Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- SZVJSHCCFOBDDC-UHFFFAOYSA-N iron(II,III) oxide Inorganic materials O=[Fe]O[Fe]O[Fe]=O SZVJSHCCFOBDDC-UHFFFAOYSA-N 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000005298 paramagnetic effect Effects 0.000 description 2
- 238000009832 plasma treatment Methods 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 210000000130 stem cell Anatomy 0.000 description 2
- 239000003104 tissue culture media Substances 0.000 description 2
- 210000000626 ureter Anatomy 0.000 description 2
- IYMAXBFPHPZYIK-BQBZGAKWSA-N Arg-Gly-Asp Chemical group NC(N)=NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(O)=O IYMAXBFPHPZYIK-BQBZGAKWSA-N 0.000 description 1
- 206010003226 Arteriovenous fistula Diseases 0.000 description 1
- 208000032170 Congenital Abnormalities Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 229910052692 Dysprosium Inorganic materials 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 229930182816 L-glutamine Natural products 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- HHZHOPJRSHTPOP-UHFFFAOYSA-N [O--].[O--].[Fe++].[Sr++] Chemical compound [O--].[O--].[Fe++].[Sr++] HHZHOPJRSHTPOP-UHFFFAOYSA-N 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000009830 antibody antigen interaction Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- UTKFUXQDBUMJSX-UHFFFAOYSA-N boron neodymium Chemical compound [B].[Nd] UTKFUXQDBUMJSX-UHFFFAOYSA-N 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000002308 calcification Effects 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 150000001735 carboxylic acids Chemical class 0.000 description 1
- 230000024245 cell differentiation Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- KBQHZAAAGSGFKK-UHFFFAOYSA-N dysprosium atom Chemical compound [Dy] KBQHZAAAGSGFKK-UHFFFAOYSA-N 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 230000002121 endocytic effect Effects 0.000 description 1
- 230000012202 endocytosis Effects 0.000 description 1
- 210000001900 endoderm Anatomy 0.000 description 1
- 230000003511 endothelial effect Effects 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 230000000799 fusogenic effect Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 239000000122 growth hormone Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 102000006495 integrins Human genes 0.000 description 1
- 108010044426 integrins Proteins 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 102000006240 membrane receptors Human genes 0.000 description 1
- 108020004084 membrane receptors Proteins 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 230000009149 molecular binding Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 238000005949 ozonolysis reaction Methods 0.000 description 1
- 210000000277 pancreatic duct Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000729 poly(L-lysine) polymer Polymers 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000006557 surface reaction Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 150000003573 thiols Chemical group 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52652203P | 2003-12-03 | 2003-12-03 | |
| US60/526,522 | 2003-12-03 | ||
| PCT/US2004/040242 WO2005056073A2 (en) | 2003-12-03 | 2004-12-02 | Kits, apparatus and methods for magnetically coating medical devices with living cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007512910A JP2007512910A (ja) | 2007-05-24 |
| JP2007512910A5 true JP2007512910A5 (enExample) | 2008-01-31 |
| JP4913602B2 JP4913602B2 (ja) | 2012-04-11 |
Family
ID=34676624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006542715A Expired - Fee Related JP4913602B2 (ja) | 2003-12-03 | 2004-12-02 | 医用デバイスに生細胞を磁気的にコーティングするためのキット、装置、および方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1699501B1 (enExample) |
| JP (1) | JP4913602B2 (enExample) |
| CN (1) | CN100556469C (enExample) |
| AT (1) | ATE544477T1 (enExample) |
| WO (1) | WO2005056073A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090118817A1 (en) | 2005-06-16 | 2009-05-07 | Mayo Foundation For Medical Education And Research | Magnetic Medical Apparatus, Kits, and Methods |
| US8465453B2 (en) | 2003-12-03 | 2013-06-18 | Mayo Foundation For Medical Education And Research | Kits, apparatus and methods for magnetically coating medical devices with living cells |
| EP1734893A4 (en) * | 2004-03-19 | 2010-04-28 | Nicanor I Moldovan | SYSTEM FOR ENSURING THE COMPATIBLITY OF AN IMPLANT WITH A RECEIVER |
| WO2008057565A2 (en) * | 2006-11-06 | 2008-05-15 | Howmedica Osteonics Corp. | Artificial cushion joints and methods of making the same |
| CN101756754B (zh) * | 2009-11-05 | 2012-01-11 | 中国人民解放军第四军医大学第一附属医院 | 磁性封堵器的制备方法 |
| US8579964B2 (en) | 2010-05-05 | 2013-11-12 | Neovasc Inc. | Transcatheter mitral valve prosthesis |
| US9554897B2 (en) | 2011-04-28 | 2017-01-31 | Neovasc Tiara Inc. | Methods and apparatus for engaging a valve prosthesis with tissue |
| US9308087B2 (en) | 2011-04-28 | 2016-04-12 | Neovasc Tiara Inc. | Sequentially deployed transcatheter mitral valve prosthesis |
| GB201116879D0 (en) | 2011-09-30 | 2011-11-16 | Magnus Stent Ic | Endoprosthesis |
| US9345573B2 (en) | 2012-05-30 | 2016-05-24 | Neovasc Tiara Inc. | Methods and apparatus for loading a prosthesis onto a delivery system |
| CN103565564B (zh) * | 2012-08-02 | 2017-02-22 | 上海微创医疗器械（集团）有限公司 | 一种含磁性底层的双面涂层药物洗脱支架及其制作方法 |
| US9572665B2 (en) | 2013-04-04 | 2017-02-21 | Neovasc Tiara Inc. | Methods and apparatus for delivering a prosthetic valve to a beating heart |
| CN104174110B (zh) * | 2013-05-23 | 2017-06-27 | 微创心脉医疗科技（上海）有限公司 | 一种药物球囊及其制备方法 |
| EP3389557B1 (en) | 2015-12-15 | 2022-07-13 | Neovasc Tiara Inc. | Transseptal delivery system |
| CN113633435B (zh) | 2016-01-29 | 2024-11-29 | 内奥瓦斯克迪亚拉公司 | 用于防止流出阻塞的假体瓣膜 |
| US10327667B2 (en) * | 2016-05-13 | 2019-06-25 | Becton, Dickinson And Company | Electro-magnetic needle catheter insertion system |
| CN113893064A (zh) | 2016-11-21 | 2022-01-07 | 内奥瓦斯克迪亚拉公司 | 用于快速收回经导管心脏瓣膜递送系统的方法和系统 |
| US10765835B2 (en) * | 2017-04-05 | 2020-09-08 | Becton, Dickinson And Company | Needle magnetizer |
| WO2019036810A1 (en) | 2017-08-25 | 2019-02-28 | Neovasc Tiara Inc. | TRANSCATHETER MITRAL VALVULE PROSTHESIS WITH SEQUENTIAL DEPLOYMENT |
| CN113271890B (zh) | 2018-11-08 | 2024-08-30 | 内奥瓦斯克迪亚拉公司 | 经导管二尖瓣假体的心室展开 |
| US11998447B2 (en) | 2019-03-08 | 2024-06-04 | Neovasc Tiara Inc. | Retrievable prosthesis delivery system |
| JP7438236B2 (ja) | 2019-04-01 | 2024-02-26 | ニオバスク ティアラ インコーポレイテッド | 制御可能に展開可能な補綴弁 |
| CN113924065A (zh) | 2019-04-10 | 2022-01-11 | 内奥瓦斯克迪亚拉公司 | 具有自然血流的假体瓣膜 |
| CA3140925A1 (en) | 2019-05-20 | 2020-11-26 | Neovasc Tiara Inc. | Introducer with hemostasis mechanism |
| US11311376B2 (en) | 2019-06-20 | 2022-04-26 | Neovase Tiara Inc. | Low profile prosthetic mitral valve |
| CN114762753B (zh) * | 2021-01-13 | 2025-04-01 | 江千里 | 磁导向装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0382465A (ja) * | 1989-08-25 | 1991-04-08 | Kanegafuchi Chem Ind Co Ltd | 磁性を有する人工血管 |
| CA2074304C (en) * | 1991-08-02 | 1996-11-26 | Cyril J. Schweich, Jr. | Drug delivery catheter |
| IL119189A0 (en) * | 1996-09-03 | 1996-12-05 | Lev Shlomo | Annulus catheter |
| US6129704A (en) * | 1997-06-12 | 2000-10-10 | Schneider (Usa) Inc. | Perfusion balloon catheter having a magnetically driven impeller |
| US6689119B1 (en) * | 2000-06-02 | 2004-02-10 | Scimed Life Systems, Inc. | Self-aligning medical device |
| ES2303851T3 (es) * | 2001-01-19 | 2008-09-01 | Boston Scientific Limited | Introductor para el despliegue de protesis ramificada. |
| US6673104B2 (en) * | 2001-03-15 | 2004-01-06 | Scimed Life Systems, Inc. | Magnetic stent |
| US20030082148A1 (en) * | 2001-10-31 | 2003-05-01 | Florian Ludwig | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo |
-
2004
- 2004-12-02 JP JP2006542715A patent/JP4913602B2/ja not_active Expired - Fee Related
- 2004-12-02 CN CNB2004800362295A patent/CN100556469C/zh not_active Expired - Fee Related
- 2004-12-02 EP EP04812694A patent/EP1699501B1/en not_active Expired - Lifetime
- 2004-12-02 WO PCT/US2004/040242 patent/WO2005056073A2/en not_active Ceased
- 2004-12-02 AT AT04812694T patent/ATE544477T1/de active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4913602B2 (ja) | 医用デバイスに生細胞を磁気的にコーティングするためのキット、装置、および方法 | |
| JP2007512910A5 (enExample) | ||
| US8465453B2 (en) | Kits, apparatus and methods for magnetically coating medical devices with living cells | |
| US9468516B2 (en) | Magnetic medical apparatus, kits, and methods | |
| US8900293B2 (en) | Magnetically-controllable delivery system for therapeutic agents | |
| US20020133225A1 (en) | Methods and apparatuses for delivering a medical agent to a medical implant | |
| US20030082148A1 (en) | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo | |
| CN103228317B (zh) | 磁性靶向装置、系统及方法 | |
| AU2007240758C1 (en) | Magnetic targeting and sequestering of therapeutic formulations | |
| EP2365007B1 (en) | Magnetically controllable drug and gene delivery stents | |
| JP2010503488A (ja) | 磁化された生体内分解性の内部人工器官 | |
| JP5243552B2 (ja) | 磁気アシスト治療薬送達の方法とシステム | |
| Tefft et al. | Magnetizable stent-grafts enable endothelial cell capture | |
| US20150313995A1 (en) | Magnetic Retention of Regenerative Cells for Wound Repair | |
| CN1950109A (zh) | 用于靶向输送的包含细胞和磁性材料的组合物 | |
| US8012200B2 (en) | Endovascular magnetic method for targeted drug delivery | |
| US20100047313A1 (en) | Medical devices having a coating for electromagnetically-controlled release of therapeutic agents | |
| JP2013000222A (ja) | 凝固性磁性粒子、及びその使用方法、並びに凝固体形成システム | |
| CA2821214C (en) | Magnetically controllable drug and gene delivery stents |