JP2007510889A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007510889A5 JP2007510889A5 JP2006534165A JP2006534165A JP2007510889A5 JP 2007510889 A5 JP2007510889 A5 JP 2007510889A5 JP 2006534165 A JP2006534165 A JP 2006534165A JP 2006534165 A JP2006534165 A JP 2006534165A JP 2007510889 A5 JP2007510889 A5 JP 2007510889A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- acrylamide
- substrate
- methacrylamide
- biomolecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 N-substituted acrylamide Chemical class 0.000 claims 77
- 239000000203 mixture Substances 0.000 claims 60
- 229920000642 polymer Polymers 0.000 claims 59
- 239000000758 substrate Substances 0.000 claims 33
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 12
- 239000000178 monomer Substances 0.000 claims 12
- 150000003140 primary amides Chemical class 0.000 claims 12
- 125000000524 functional group Chemical group 0.000 claims 11
- 239000011248 coating agent Substances 0.000 claims 10
- 238000000576 coating method Methods 0.000 claims 10
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 8
- 125000000217 alkyl group Chemical group 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 238000002493 microarray Methods 0.000 claims 8
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical class CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 claims 4
- WUIJTQZXUURFQU-UHFFFAOYSA-N 1-methylsulfonylethene Chemical compound CS(=O)(=O)C=C WUIJTQZXUURFQU-UHFFFAOYSA-N 0.000 claims 4
- FTALTLPZDVFJSS-UHFFFAOYSA-N 2-(2-ethoxyethoxy)ethyl prop-2-enoate Chemical compound CCOCCOCCOC(=O)C=C FTALTLPZDVFJSS-UHFFFAOYSA-N 0.000 claims 4
- XWRBMHSLXKNRJX-UHFFFAOYSA-N 2-ethenyl-1-oxidopyridin-1-ium Chemical compound [O-][N+]1=CC=CC=C1C=C XWRBMHSLXKNRJX-UHFFFAOYSA-N 0.000 claims 4
- MXRGSJAOLKBZLU-UHFFFAOYSA-N 3-ethenylazepan-2-one Chemical compound C=CC1CCCCNC1=O MXRGSJAOLKBZLU-UHFFFAOYSA-N 0.000 claims 4
- KWOLFJPFCHCOCG-UHFFFAOYSA-N Acetophenone Chemical compound CC(=O)C1=CC=CC=C1 KWOLFJPFCHCOCG-UHFFFAOYSA-N 0.000 claims 4
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 claims 4
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 4
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 4
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 claims 4
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 claims 4
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical group CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 claims 4
- PNLUGRYDUHRLOF-UHFFFAOYSA-N n-ethenyl-n-methylacetamide Chemical compound C=CN(C)C(C)=O PNLUGRYDUHRLOF-UHFFFAOYSA-N 0.000 claims 4
- 229920001451 polypropylene glycol Polymers 0.000 claims 4
- 150000003961 organosilicon compounds Chemical class 0.000 claims 3
- XLPJNCYCZORXHG-UHFFFAOYSA-N 1-morpholin-4-ylprop-2-en-1-one Chemical compound C=CC(=O)N1CCOCC1 XLPJNCYCZORXHG-UHFFFAOYSA-N 0.000 claims 2
- AKVUWTYSNLGBJY-UHFFFAOYSA-N 2-methyl-1-morpholin-4-ylprop-2-en-1-one Chemical compound CC(=C)C(=O)N1CCOCC1 AKVUWTYSNLGBJY-UHFFFAOYSA-N 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 2
- 150000001299 aldehydes Chemical class 0.000 claims 2
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 claims 2
- 150000004056 anthraquinones Chemical class 0.000 claims 2
- RJGDLRCDCYRQOQ-UHFFFAOYSA-N anthrone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3CC2=C1 RJGDLRCDCYRQOQ-UHFFFAOYSA-N 0.000 claims 2
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 claims 2
- 239000012965 benzophenone Substances 0.000 claims 2
- 150000002118 epoxides Chemical class 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 230000003100 immobilizing effect Effects 0.000 claims 2
- 150000002540 isothiocyanates Chemical class 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- WFKDPJRCBCBQNT-UHFFFAOYSA-N n,2-dimethylprop-2-enamide Chemical compound CNC(=O)C(C)=C WFKDPJRCBCBQNT-UHFFFAOYSA-N 0.000 claims 2
- QRWZCJXEAOZAAW-UHFFFAOYSA-N n,n,2-trimethylprop-2-enamide Chemical compound CN(C)C(=O)C(C)=C QRWZCJXEAOZAAW-UHFFFAOYSA-N 0.000 claims 2
- JMCVCHBBHPFWBF-UHFFFAOYSA-N n,n-diethyl-2-methylprop-2-enamide Chemical compound CCN(CC)C(=O)C(C)=C JMCVCHBBHPFWBF-UHFFFAOYSA-N 0.000 claims 2
- OVHHHVAVHBHXAK-UHFFFAOYSA-N n,n-diethylprop-2-enamide Chemical compound CCN(CC)C(=O)C=C OVHHHVAVHBHXAK-UHFFFAOYSA-N 0.000 claims 2
- OHLHOLGYGRKZMU-UHFFFAOYSA-N n-benzylprop-2-enamide Chemical compound C=CC(=O)NCC1=CC=CC=C1 OHLHOLGYGRKZMU-UHFFFAOYSA-N 0.000 claims 2
- PMJFVKWBSWWAKT-UHFFFAOYSA-N n-cyclohexylprop-2-enamide Chemical compound C=CC(=O)NC1CCCCC1 PMJFVKWBSWWAKT-UHFFFAOYSA-N 0.000 claims 2
- ZIWDVJPPVMGJGR-UHFFFAOYSA-N n-ethyl-2-methylprop-2-enamide Chemical compound CCNC(=O)C(C)=C ZIWDVJPPVMGJGR-UHFFFAOYSA-N 0.000 claims 2
- AWGZKFQMWZYCHF-UHFFFAOYSA-N n-octylprop-2-enamide Chemical compound CCCCCCCCNC(=O)C=C AWGZKFQMWZYCHF-UHFFFAOYSA-N 0.000 claims 2
- BPCNEKWROYSOLT-UHFFFAOYSA-N n-phenylprop-2-enamide Chemical compound C=CC(=O)NC1=CC=CC=C1 BPCNEKWROYSOLT-UHFFFAOYSA-N 0.000 claims 2
- QNILTEGFHQSKFF-UHFFFAOYSA-N n-propan-2-ylprop-2-enamide Chemical compound CC(C)NC(=O)C=C QNILTEGFHQSKFF-UHFFFAOYSA-N 0.000 claims 2
- 239000004033 plastic Substances 0.000 claims 2
- 229920003023 plastic Polymers 0.000 claims 2
- 239000010703 silicon Substances 0.000 claims 2
- 229910052710 silicon Inorganic materials 0.000 claims 2
- 229910052990 silicon hydride Inorganic materials 0.000 claims 2
- 125000003277 amino group Chemical group 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 1
- 239000002023 wood Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/677,022 | 2003-10-01 | ||
| US10/677,022 US7309593B2 (en) | 2003-10-01 | 2003-10-01 | Attachment of molecules to surfaces |
| PCT/US2004/032443 WO2005033158A2 (en) | 2003-10-01 | 2004-09-30 | Attachment of molecules to surfaces |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007510889A JP2007510889A (ja) | 2007-04-26 |
| JP2007510889A5 true JP2007510889A5 (enExample) | 2007-11-01 |
| JP4741499B2 JP4741499B2 (ja) | 2011-08-03 |
Family
ID=34393654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006534165A Expired - Lifetime JP4741499B2 (ja) | 2003-10-01 | 2004-09-30 | 表面への分子の結合 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7309593B2 (enExample) |
| EP (1) | EP1668050B1 (enExample) |
| JP (1) | JP4741499B2 (enExample) |
| AT (1) | ATE448258T1 (enExample) |
| AU (1) | AU2004278408B2 (enExample) |
| CA (1) | CA2536303C (enExample) |
| DE (1) | DE602004024095D1 (enExample) |
| WO (1) | WO2005033158A2 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6433154B1 (en) * | 1997-06-12 | 2002-08-13 | Bristol-Myers Squibb Company | Functional receptor/kinase chimera in yeast cells |
| AU2001261625B2 (en) * | 2000-05-16 | 2006-04-06 | Regents Of The University Of Minnesota | High mass throughput particle generation using multiple nozzle spraying |
| US7247338B2 (en) * | 2001-05-16 | 2007-07-24 | Regents Of The University Of Minnesota | Coating medical devices |
| EP1615034A4 (en) * | 2003-03-31 | 2010-11-24 | Rikagaku Kenkyusho | FIXING AGENTS, METHOD FOR FIXING A SUBSTANCE USING SAID AGENTS, AND SUBSTRATE HAVING A SUBSTANCE FIXED WITH SAID AGENTS |
| US7309593B2 (en) * | 2003-10-01 | 2007-12-18 | Surmodics, Inc. | Attachment of molecules to surfaces |
| EP2168975A3 (en) | 2004-05-24 | 2012-01-11 | Genvault Corporation | Method of stably storing biomolecules in recoverable form |
| WO2006014680A1 (en) * | 2004-07-19 | 2006-02-09 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| US7935479B2 (en) | 2004-07-19 | 2011-05-03 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| US7846676B2 (en) * | 2004-07-19 | 2010-12-07 | Cell Biosciences, Inc. | Methods and devices for analyte detection |
| JP2008536128A (ja) | 2005-04-09 | 2008-09-04 | セル バイオサイエンシズ，インコーポレイテッド | 自動化微小体積アッセイシステム |
| US8945361B2 (en) | 2005-09-20 | 2015-02-03 | ProteinSimple | Electrophoresis standards, methods and kits |
| US8117902B2 (en) * | 2005-11-03 | 2012-02-21 | University Of Massachusetts | Nanopatterned surfaces and related methods for selective adhesion, sensing and separation |
| CN1962155A (zh) * | 2005-11-10 | 2007-05-16 | 鸿富锦精密工业（深圳）有限公司 | 一种二氧化碳激光焊接装置 |
| CA2637883C (en) | 2006-01-31 | 2015-07-07 | Regents Of The University Of Minnesota | Electrospray coating of objects |
| WO2007089883A2 (en) * | 2006-01-31 | 2007-08-09 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
| US9108217B2 (en) | 2006-01-31 | 2015-08-18 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
| US20080017512A1 (en) * | 2006-07-24 | 2008-01-24 | Bordunov Andrei V | Coatings for capillaries capable of capturing analytes |
| US9040816B2 (en) * | 2006-12-08 | 2015-05-26 | Nanocopoeia, Inc. | Methods and apparatus for forming photovoltaic cells using electrospray |
| JP5423965B2 (ja) * | 2007-05-30 | 2014-02-19 | Ｊｓｒ株式会社 | 非特異吸着防止剤 |
| WO2009005718A1 (en) * | 2007-06-28 | 2009-01-08 | Surmodics, Inc. | Polypeptide microparticles having sustained release characteristics, methods and uses |
| US20100209957A1 (en) * | 2008-06-20 | 2010-08-19 | Genvault Corporation | Biosample storage devices and methods of use thereof |
| US8382858B2 (en) | 2008-06-25 | 2013-02-26 | University Of Massachusetts | Nanoparticle-textured surfaces and related methods for selective adhesion, sensing and separation |
| JP2012501681A (ja) | 2008-09-12 | 2012-01-26 | ジェンボールト コーポレイション | 生体分子の貯蔵および安定化のためのマトリックスおよび媒体 |
| EP2424581B1 (en) | 2009-04-28 | 2017-03-01 | SurModics, Inc. | Devices and methods for delivery of bioactive agents |
| US20110144373A1 (en) * | 2009-12-10 | 2011-06-16 | Surmodics, Inc. | Water-soluble degradable photo-crosslinker |
| US10315987B2 (en) | 2010-12-13 | 2019-06-11 | Surmodics, Inc. | Photo-crosslinker |
| US9861814B2 (en) | 2010-12-23 | 2018-01-09 | Medtronic, Inc. | Medical electrical lead having biological surface and methods of making and using same |
| CA2827435C (en) | 2011-02-15 | 2018-11-27 | Eli Lilly And Company | Methods for controlling pain in canines using a transdermal solution of fentanyl |
| US10213529B2 (en) | 2011-05-20 | 2019-02-26 | Surmodics, Inc. | Delivery of coated hydrophobic active agent particles |
| US9861727B2 (en) | 2011-05-20 | 2018-01-09 | Surmodics, Inc. | Delivery of hydrophobic active agent particles |
| US9757497B2 (en) | 2011-05-20 | 2017-09-12 | Surmodics, Inc. | Delivery of coated hydrophobic active agent particles |
| US9108195B2 (en) * | 2011-06-24 | 2015-08-18 | The Regents Of The University Of California | Microfluidic devices and methods for separating and detecting constituents in a fluid sample |
| EP2814857A1 (en) * | 2012-02-17 | 2014-12-24 | NVS Technologies Inc. | Polymer scaffolds for assay applications |
| US9012022B2 (en) * | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| EP2906607A2 (en) * | 2012-10-12 | 2015-08-19 | NVS Technologies Inc. | Polymers having orthogonal reactive groups and uses thereof |
| US11246963B2 (en) | 2012-11-05 | 2022-02-15 | Surmodics, Inc. | Compositions and methods for delivery of hydrophobic active agents |
| WO2014071387A1 (en) | 2012-11-05 | 2014-05-08 | Surmodics, Inc. | Composition and method for delivery of hydrophobic active agents |
| US10267795B2 (en) | 2013-03-07 | 2019-04-23 | The Regents Of The University Of California | Electrophoretic separation devices and methods for using the same |
| KR20150135353A (ko) * | 2013-03-14 | 2015-12-02 | 엔브이에스 테크놀로지스 인코포레이티드 | 생체 분자를 격리시키기 위한 표면 산화 및 관련 방법 |
| CN120114655A (zh) | 2015-01-29 | 2025-06-10 | 苏尔莫迪克斯公司 | 疏水性活性剂颗粒的递送 |
| US10478546B2 (en) | 2015-09-15 | 2019-11-19 | Surmodics, Inc. | Hemodialysis catheter sleeve |
| US10377928B2 (en) | 2015-12-10 | 2019-08-13 | Ppg Industries Ohio, Inc. | Structural adhesive compositions |
| US20170281914A1 (en) | 2016-03-31 | 2017-10-05 | Surmodics, Inc. | Localized treatment of tissues through transcatheter delivery of active agents |
| US10918835B2 (en) | 2016-03-31 | 2021-02-16 | Surmodics, Inc. | Delivery system for active agent coated balloon |
| US10806904B2 (en) | 2016-03-31 | 2020-10-20 | Surmodics, Inc. | Two-part insertion tool and methods |
| US10391292B2 (en) | 2016-06-15 | 2019-08-27 | Surmodics, Inc. | Hemostasis sealing device with constriction ring |
| AU2017325722B2 (en) | 2016-09-16 | 2023-11-30 | Surmodics, Inc. | Lubricious insertion tools for medical devices and methods for using |
| US10758719B2 (en) | 2016-12-15 | 2020-09-01 | Surmodics, Inc. | Low-friction sealing devices |
| US10898446B2 (en) | 2016-12-20 | 2021-01-26 | Surmodics, Inc. | Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces |
| US12226552B2 (en) | 2019-09-30 | 2025-02-18 | Surmodics, Inc. | Active agent depots formed in situ |
| TWI899211B (zh) | 2020-04-17 | 2025-10-01 | 小利蘭史丹佛大學董事會 | 用於生物醫藥調配物之聚合物賦形劑 |
| US12624392B2 (en) | 2020-12-30 | 2026-05-12 | 10X Genomics, Inc. | Molecular array generation using photoresist |
| WO2022147139A1 (en) | 2020-12-30 | 2022-07-07 | 10X Genomics, Inc. | Methods and compositions for light-controlled surface patterning using a polymer |
| US20220228201A1 (en) | 2020-12-30 | 2022-07-21 | 10X Genomics, Inc. | Molecular arrays and methods for generating and using the arrays |
| EP4346879A4 (en) * | 2021-05-24 | 2025-04-09 | Peri-Ness Technologies Ltd | Therapeutic regimen with dnase |
| EP4514346A1 (en) | 2022-04-25 | 2025-03-05 | SurModics, Inc. | Medical device coatings with microcrystalline active agents |
| US12144862B2 (en) | 2022-05-23 | 2024-11-19 | The Board Of Trustees Of The Leland Stanford Junior University | Antibody biopharmaceutical formulations including polymer excipients |
| ES3005088T3 (en) | 2022-06-29 | 2025-03-13 | 10X Genomics Inc | High definition molecular array feature generation using photoresist |
| US20240060127A1 (en) | 2022-06-29 | 2024-02-22 | 10X Genomics, Inc. | Methods and systems for light-controlled surface patterning using photomasks |
| WO2024006799A1 (en) | 2022-06-29 | 2024-01-04 | 10X Genomics, Inc. | Covalent attachment of splint oligonucleotides for molecular array generation using ligation |
| CN122070292A (zh) * | 2023-10-24 | 2026-05-19 | 普罗美加公司 | 用于分离核酸的聚合物、组合物和方法 |
| WO2025101377A1 (en) | 2023-11-09 | 2025-05-15 | 10X Genomics, Inc. | Matrix-assisted spatial analysis of biological samples |
| DE102023136339A1 (de) | 2023-12-21 | 2025-06-26 | Schott Technical Glass Solutions Gmbh | Verfahren und Beschichtungssystem zur Immobilisierung von Biomolekülen |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5073484A (en) | 1982-03-09 | 1991-12-17 | Bio-Metric Systems, Inc. | Quantitative analysis apparatus and method |
| US4973493A (en) | 1982-09-29 | 1990-11-27 | Bio-Metric Systems, Inc. | Method of improving the biocompatibility of solid surfaces |
| US4722906A (en) | 1982-09-29 | 1988-02-02 | Bio-Metric Systems, Inc. | Binding reagents and methods |
| US5512329A (en) | 1982-09-29 | 1996-04-30 | Bsi Corporation | Substrate surface preparation |
| US5217492A (en) | 1982-09-29 | 1993-06-08 | Bio-Metric Systems, Inc. | Biomolecule attachment to hydrophobic surfaces |
| US5002582A (en) | 1982-09-29 | 1991-03-26 | Bio-Metric Systems, Inc. | Preparation of polymeric surfaces via covalently attaching polymers |
| US4542102A (en) | 1983-07-05 | 1985-09-17 | Molecular Diagnostics, Inc. | Coupling of nucleic acids to solid support by photochemical methods |
| US4582860A (en) | 1983-12-15 | 1986-04-15 | Rohm And Haas Company | Oxirane resins for enzyme immobilization |
| US4979959A (en) | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
| DK0484472T3 (da) | 1990-04-12 | 1997-08-11 | Max Dolder | Fremgangsmåde til lysinduceret immobilisering af biomolekyler på kemisk "inerte" overflader |
| FR2679255B1 (fr) | 1991-07-17 | 1993-10-22 | Bio Merieux | Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation. |
| JP3455217B2 (ja) | 1992-02-13 | 2003-10-14 | バイオ−メトリック システムズ インコーポレイテッド | 架橋マトリックス中の化学種の固定 |
| US5512474A (en) | 1992-05-29 | 1996-04-30 | Bsi Corporation | Cell culture support containing a cell adhesion factor and a positively-charged molecule |
| US5414075A (en) | 1992-11-06 | 1995-05-09 | Bsi Corporation | Restrained multifunctional reagent for surface modification |
| WO1994017447A1 (en) | 1993-01-21 | 1994-08-04 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Chemical functionalization of surfaces |
| US5610287A (en) | 1993-12-06 | 1997-03-11 | Molecular Tool, Inc. | Method for immobilizing nucleic acid molecules |
| US5643580A (en) | 1994-10-17 | 1997-07-01 | Surface Genesis, Inc. | Biocompatible coating, medical device using the same and methods |
| US5707818A (en) | 1994-12-13 | 1998-01-13 | Bsi Corporation | Device and method for simultaneously performing multiple competitive immunoassays |
| CA2222136C (en) | 1995-05-26 | 2005-04-05 | Bsi Corporation | Method and implantable article for promoting endothelialization |
| US5783502A (en) | 1995-06-07 | 1998-07-21 | Bsi Corporation | Virus inactivating coatings |
| DE19533682A1 (de) | 1995-09-12 | 1997-03-13 | Biotronik Mess & Therapieg | Verfahren zum Anlagern und Immobilisieren von Heparin auf anorganischen Substratoberflächen von kardiovaskulären Implantanten |
| US5714360A (en) | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| US5942555A (en) | 1996-03-21 | 1999-08-24 | Surmodics, Inc. | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom |
| WO1997046313A1 (en) | 1996-06-07 | 1997-12-11 | Eos Biotechnology, Inc. | Immobilised linear oligonucleotide arrays |
| US5981734A (en) | 1997-07-17 | 1999-11-09 | University Of Chicago | Methods for immobilizing nucleic acids on a gel substrate |
| US6465178B2 (en) | 1997-09-30 | 2002-10-15 | Surmodics, Inc. | Target molecule attachment to surfaces |
| US5858653A (en) | 1997-09-30 | 1999-01-12 | Surmodics, Inc. | Reagent and method for attaching target molecules to a surface |
| DE19804518C2 (de) | 1998-02-05 | 2000-10-05 | Roehm Gmbh | Verfahren zur Herstellung von perlförmigen Mischpolymerisaten auf Acrylatbasis, danach hergestellte Trägerpolymermaterialien und deren Verwendung |
| US6410044B1 (en) | 1998-03-19 | 2002-06-25 | Surmodics, Inc. | Crosslinkable macromers |
| US6376619B1 (en) | 1998-04-13 | 2002-04-23 | 3M Innovative Properties Company | High density, miniaturized arrays and methods of manufacturing same |
| AU3628999A (en) | 1998-05-08 | 1999-11-29 | Kyowa Medex Co., Ltd. | Method for quantitating specific gene sequence and quantitating reagent |
| US6254634B1 (en) | 1998-06-10 | 2001-07-03 | Surmodics, Inc. | Coating compositions |
| CN1144824C (zh) * | 1999-07-01 | 2004-04-07 | 旭化成株式会社 | 低分子量甲醛聚合物和含有它的组合物 |
| DE60027309T2 (de) | 1999-07-02 | 2006-08-31 | Symyx Technologies, Inc., Santa Clara | Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen |
| US6250044B1 (en) * | 2000-01-13 | 2001-06-26 | Kohler Co. | Shower door bar with recessed grip |
| US6410643B1 (en) * | 2000-03-09 | 2002-06-25 | Surmodics, Inc. | Solid phase synthesis method and reagent |
| ATE402198T1 (de) | 2002-11-29 | 2008-08-15 | Marcella Chiari | Verfahren zur immobilisierung biologischer moleküle an feste oberflächen |
| US7820158B2 (en) | 2003-04-10 | 2010-10-26 | Surmodics, Inc. | Ligand-coupled initiator polymers and methods of use |
| US7309593B2 (en) * | 2003-10-01 | 2007-12-18 | Surmodics, Inc. | Attachment of molecules to surfaces |
-
2003
- 2003-10-01 US US10/677,022 patent/US7309593B2/en not_active Expired - Lifetime
-
2004
- 2004-09-30 EP EP04789464A patent/EP1668050B1/en not_active Expired - Lifetime
- 2004-09-30 AT AT04789464T patent/ATE448258T1/de not_active IP Right Cessation
- 2004-09-30 JP JP2006534165A patent/JP4741499B2/ja not_active Expired - Lifetime
- 2004-09-30 DE DE200460024095 patent/DE602004024095D1/de not_active Expired - Lifetime
- 2004-09-30 WO PCT/US2004/032443 patent/WO2005033158A2/en not_active Ceased
- 2004-09-30 AU AU2004278408A patent/AU2004278408B2/en not_active Expired
- 2004-09-30 CA CA 2536303 patent/CA2536303C/en not_active Expired - Lifetime
-
2007
- 2007-09-14 US US11/901,033 patent/US7829317B2/en not_active Expired - Lifetime
-
2010
- 2010-09-09 US US12/878,236 patent/US8129159B2/en not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4741499B2 (ja) | 表面への分子の結合 | |
| US6815078B2 (en) | Substrate for protein microarray containing functionalized polymer | |
| Zhou et al. | Recent developments in PDMS surface modification for microfluidic devices | |
| EP1974214B1 (en) | Supports for assaying analytes and methods of making and using thereof | |
| EP2713158A1 (en) | Coatings for capillaries capable of capturing analytes | |
| US20030008413A1 (en) | Methods of making and using substrate surfaces having covalently bound polyelectrolyte films | |
| WO2001067129A3 (en) | Epoxide polymer surfaces | |
| WO2007100356A3 (en) | A microfluidic interface for highly parallel addressing of sensing arrays | |
| JP2009518649A5 (enExample) | ||
| JP2005249572A5 (enExample) | ||
| DE60041255D1 (de) | Polyionische beschichtungen für analytische und sensor-vorrichtungen | |
| JP2002544508A5 (enExample) | ||
| JP2005526259A (ja) | 導電性マイクロプレート | |
| WO2005029095A1 (ja) | バイオチップ | |
| ATE532066T1 (de) | Oberflächenimmobilisierter polyelektrolyt mit mehreren, zur kovalenten bindung an biomoleküle fähigen funktionellen gruppen | |
| WO2003020978B1 (en) | Method for manufacturing hydrogel biochip by using star-like polyethylene glycol derivative having epoxy group | |
| US6797393B2 (en) | Method for making biochip substrate | |
| JP2006522936A (ja) | 改良複合体の微小配列スライド | |
| EP2556095A1 (en) | Silane copolymers and uses thereof | |
| US20080293592A1 (en) | Method For Covalently Immobilising Biomolecules on Organic Surfaces | |
| JP4811355B2 (ja) | バイオデバイスおよびその製造方法、並びにバイオセンサー | |
| JP2006515417A (ja) | 選択的で位置合わせ不要な表面上の分子パターニング | |
| US20060111517A1 (en) | Recognition layers made of hydrogel based on polyacrylamide for use in biosensor technology | |
| US20070154888A1 (en) | Method for the covalent immobilization of probe biomolecules on organic surfaces | |
| CN1826528A (zh) | 用于蛋白质生物芯片的明胶基基质 |