JP2007508527A5 - - Google Patents

Download PDF

Info

Publication number
JP2007508527A5
JP2007508527A5 JP2006530040A JP2006530040A JP2007508527A5 JP 2007508527 A5 JP2007508527 A5 JP 2007508527A5 JP 2006530040 A JP2006530040 A JP 2006530040A JP 2006530040 A JP2006530040 A JP 2006530040A JP 2007508527 A5 JP2007508527 A5 JP 2007508527A5
Authority
JP
Japan
Prior art keywords
organ damage
end organ
marker
level
risk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006530040A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007508527A (ja
JP4840744B2 (ja
Filing date
Publication date
Priority claimed from EP03078161A external-priority patent/EP1522857A1/en
Application filed filed Critical
Publication of JP2007508527A publication Critical patent/JP2007508527A/ja
Publication of JP2007508527A5 publication Critical patent/JP2007508527A5/ja
Application granted granted Critical
Publication of JP4840744B2 publication Critical patent/JP4840744B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006530040A 2003-10-09 2004-09-27 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法 Expired - Fee Related JP4840744B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03078161.1 2003-10-09
EP03078161A EP1522857A1 (en) 2003-10-09 2003-10-09 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
PCT/EP2004/010879 WO2005040817A1 (en) 2003-10-09 2004-09-27 Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010167334A Division JP2010279378A (ja) 2003-10-09 2010-07-26 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2011088342A Division JP5580774B2 (ja) 2003-10-09 2011-04-12 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法

Publications (3)

Publication Number Publication Date
JP2007508527A JP2007508527A (ja) 2007-04-05
JP2007508527A5 true JP2007508527A5 (cg-RX-API-DMAC7.html) 2007-08-02
JP4840744B2 JP4840744B2 (ja) 2011-12-21

Family

ID=34306912

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2006530040A Expired - Fee Related JP4840744B2 (ja) 2003-10-09 2004-09-27 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2010167334A Withdrawn JP2010279378A (ja) 2003-10-09 2010-07-26 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2011088342A Expired - Lifetime JP5580774B2 (ja) 2003-10-09 2011-04-12 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2014021394A Expired - Lifetime JP5789009B2 (ja) 2003-10-09 2014-02-06 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2015081540A Pending JP2015171365A (ja) 2003-10-09 2015-04-13 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2010167334A Withdrawn JP2010279378A (ja) 2003-10-09 2010-07-26 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2011088342A Expired - Lifetime JP5580774B2 (ja) 2003-10-09 2011-04-12 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2014021394A Expired - Lifetime JP5789009B2 (ja) 2003-10-09 2014-02-06 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法
JP2015081540A Pending JP2015171365A (ja) 2003-10-09 2015-04-13 ガレクチン−3またはトロンボスポンジン−2のレベルを定量することによって心不全を発症する危険性がある対象を同定する方法

Country Status (14)

Country Link
US (5) US7888137B2 (cg-RX-API-DMAC7.html)
EP (4) EP1522857A1 (cg-RX-API-DMAC7.html)
JP (5) JP4840744B2 (cg-RX-API-DMAC7.html)
CN (2) CN1879022B (cg-RX-API-DMAC7.html)
AT (1) ATE532073T1 (cg-RX-API-DMAC7.html)
AU (2) AU2004284496C1 (cg-RX-API-DMAC7.html)
CA (2) CA2542033C (cg-RX-API-DMAC7.html)
CY (2) CY1112359T1 (cg-RX-API-DMAC7.html)
DK (2) DK1682907T3 (cg-RX-API-DMAC7.html)
ES (2) ES2530567T3 (cg-RX-API-DMAC7.html)
PL (2) PL2317324T3 (cg-RX-API-DMAC7.html)
PT (2) PT2317324E (cg-RX-API-DMAC7.html)
SI (2) SI1682907T1 (cg-RX-API-DMAC7.html)
WO (1) WO2005040817A1 (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1522857A1 (en) * 2003-10-09 2005-04-13 Universiteit Maastricht Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
JP2010504089A (ja) * 2006-09-25 2010-02-12 ユニフェルジテイト・マーストリヒト 心不全を発生させる危険がある被検者を診断および/または処置するための手段および方法
EP2109688A4 (en) * 2007-01-23 2010-02-17 Univ Virginia GALECTIN-3 BINDING PROTEIN AS BIOMARKER FOR HEART CIRCULATION DISEASES
JP2010539493A (ja) * 2007-09-17 2010-12-16 ビージー メディシン, インコーポレイテッド ペルオキシソーム−増殖因子−活性化因子−レセプター−γアゴニストもしくはチアゾリジンジオンで処置されたか処置される可能性のある患者における欝血性心リスクの評価
EP3971570A3 (en) * 2008-10-29 2022-11-09 BG Medicine, Inc. Galectin-3 immunoassay
MX2012002371A (es) * 2009-08-25 2012-06-08 Bg Medicine Inc Galectina-3 y terapia de resincronizacion cardiaca.
US20120029003A1 (en) * 2010-07-02 2012-02-02 Bg Medicine, Inc. Galectin-3 and statin therapy
US8703433B2 (en) * 2010-10-18 2014-04-22 Hideaki Hara Marker for amyotrophic lateral sclerosis, and use thereof
EP2460890A1 (en) * 2010-12-01 2012-06-06 Max-Delbrück-Centrum für Molekulare Medizin (MDC) Gpnmb/Osteoactivin as a drug target and biomarker in cardiac diseases
EP2671080A1 (en) * 2011-01-31 2013-12-11 BG Medicine, Inc. Use of galectin-3 for detecting and prognosing heart failure after acute coronary syndrome
ES2897419T3 (es) 2011-03-17 2022-03-01 Critical Care Diagnostics Inc Procedimientos de predicción del riesgo de un resultado clínico adverso
AR086543A1 (es) * 2011-05-25 2014-01-08 Bg Medicine Inc Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica
BR112014012823A2 (pt) * 2011-12-08 2015-09-29 Isaac Eliaz redução dos níveis de galectina-3 por meio de plasmaferese
ES2742291T3 (es) * 2012-09-27 2020-02-13 Siemens Healthcare Diagnostics Inc Cistatina C y Galectina-3 como biomarcadores para la hipertensión arterial pulmonar
JP6366598B2 (ja) * 2012-11-15 2018-08-01 タフツ ユニバーシティー ガレクチンタンパク質阻害剤を用いて被験体の眼の血管新生または繊維症を処置し、調節し、または、予防する方法、組成物、およびキット
WO2016113719A1 (en) 2015-01-18 2016-07-21 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin d values in ratio with pth as a prognostic biomarker
US10688565B2 (en) * 2015-05-28 2020-06-23 Kyocera Corporation Cutting tool
CN112553335A (zh) * 2020-12-17 2021-03-26 核工业总医院 肾细胞癌生物标志物及其应用

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4704692A (en) * 1986-09-02 1987-11-03 Ladner Robert C Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US5091513A (en) * 1987-05-21 1992-02-25 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
US5132405A (en) * 1987-05-21 1992-07-21 Creative Biomolecules, Inc. Biosynthetic antibody binding sites
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US20010051350A1 (en) * 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
BE1010935A7 (nl) * 1997-02-19 1999-03-02 Delanghe Joris Richard Siegfri Fenotypering van humaan haptoglobine in serum of plasma door middel van quantitatieve agglutinatie met streptococcus antigenen.
AU7590198A (en) * 1997-06-10 1998-12-30 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
US20060166276A1 (en) * 1997-09-05 2006-07-27 Lung Health Diagnostics Pty Ltd Method of diagnosis and agents useful for same
IL134880A0 (en) * 1997-09-05 2001-05-20 Univ Southern Australia A method of diagnosis
ATE298423T1 (de) * 1997-10-24 2005-07-15 Shionogi & Co Verfahren zur inhibierung des abbaus von natriuretischen peptiden und verbesserte methode zum bestimmen der natriuretischen peptide
ATE332144T1 (de) * 1998-04-02 2006-07-15 Genentech Inc Behandlung von herzhypertrophie
RU2218568C2 (ru) * 1999-01-29 2003-12-10 Роше Диагностикс Гмбх Способ обнаружения n-концевого про-мнп
JP2003504088A (ja) * 1999-02-19 2003-02-04 ザ ユニヴァーシティー オブ アイオワ リサーチ ファンデーション 黄斑変性に関する診断および治療
JP2003507076A (ja) * 1999-08-20 2003-02-25 ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システム 心臓の遺伝子発現の調節におけるhdac4およびhdac5
AU2001236589A1 (en) 2000-02-04 2001-08-14 Aeomica, Inc. Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes
AU2001251351A1 (en) 2000-04-05 2001-10-23 Incyte Genomics, Inc. Genes expressed in foam cell differentiation
KR100395254B1 (ko) * 2000-10-30 2003-08-21 (주)자리타 바이오텍 종양 발생 예측 키트
WO2002038794A2 (en) * 2000-11-09 2002-05-16 The Brigham And Women's Hospital, Inc. Cardiovascular disease diagnostic and therapeutic targets
WO2002039122A2 (en) * 2000-11-09 2002-05-16 Vitivity, Inc. Methods for the identification and the treatment of cardiovascular disease
CA2431861A1 (en) * 2000-12-08 2002-06-13 Curagen Corporation Method of detecting and treating tuberous sclerosis complex associated disorders
JP4035562B2 (ja) * 2001-01-31 2008-01-23 国立大学法人富山大学 ガレクチン−3誘導能を利用した物質のスクリーニング方法、肝の状態の診断方法およびこれらの方法を利用したキット
CA2441086A1 (en) 2001-03-19 2002-09-26 Wisconsin Alumni Research Foundation Identification of gene expression alterations underlying the aging process in mammals
US20060019235A1 (en) 2001-07-02 2006-01-26 The Board Of Trustees Of The Leland Stanford Junior University Molecular and functional profiling using a cellular microarray
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
US20030099958A1 (en) * 2001-09-05 2003-05-29 Vitivity, Inc. Diagnosis and treatment of vascular disease
GB0124145D0 (en) 2001-10-08 2001-11-28 Bayer Ag Genes and proteins for prevention,prediction,prognosis and therapy of cardiovascular disease
US20060141493A1 (en) 2001-11-09 2006-06-29 Duke University Office Of Science And Technology Atherosclerotic phenotype determinative genes and methods for using the same
WO2003095667A2 (en) * 2002-05-13 2003-11-20 Arexis Ab Autoimmune conditions and nadph oxidase defects
AU2003290537A1 (en) 2002-10-24 2004-05-13 Duke University Binary prediction tree modeling with many predictors and its uses in clinical and genomic applications
US7611839B2 (en) 2002-11-21 2009-11-03 Wyeth Methods for diagnosing RCC and other solid tumors
EP1431399A1 (en) * 2002-12-20 2004-06-23 Clinigenetics Methods and composition for identifying therapeutic agents of atherosclerotic plaque lesions
US6889083B2 (en) * 2003-04-21 2005-05-03 Medtronic, Inc. Atrial tracking recovery to restore cardiac resynchronization therapy in dual chamber tracking modes
WO2005020784A2 (en) 2003-05-23 2005-03-10 Mount Sinai School Of Medicine Of New York University Surrogate cell gene expression signatures for evaluating the physical state of a subject
US20060257946A1 (en) 2003-06-06 2006-11-16 Ciphergen Biosystems, Inc Serum biomarkers in ischaemic heart disease
US20050106100A1 (en) 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
EP1560025A3 (en) * 2003-10-03 2011-09-07 F. Hoffmann-La Roche AG Specific markers for diabetes
EP1522857A1 (en) * 2003-10-09 2005-04-13 Universiteit Maastricht Method for identifying a subject at risk of developing heart failure by determining the level of galectin-3 or thrombospondin-2
DE10347436B4 (de) * 2003-10-13 2007-08-02 Johann Wolfgang Goethe-Universität Frankfurt am Main In vitro Verfahren zur Diagnose der kardiovaskulären Funktionalität von Blut-abgeleiteter zirkulierender Vorläuferzellen (BDP)
US20060019890A1 (en) 2004-01-15 2006-01-26 Kapoun Ann M Method for treating cardiac remodeling following myocardial injury
WO2006026074A2 (en) 2004-08-04 2006-03-09 Duke University Atherosclerotic phenotype determinative genes and methods for using the same
US20090258002A1 (en) 2005-02-01 2009-10-15 Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services Biomarkers for Tissue Status
WO2006102497A2 (en) 2005-03-22 2006-09-28 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for diagnosis, monitoring and development of therapeutics for treatment of atherosclerotic disease
US7632634B2 (en) 2005-04-15 2009-12-15 University Of Maryland Biotechnology Institute Method and assay for early diagnosis of prostate cancer
US9592970B2 (en) * 2008-07-17 2017-03-14 Toby D. Henderson Robotic gantry with end effector for product lifting
EP3971570A3 (en) * 2008-10-29 2022-11-09 BG Medicine, Inc. Galectin-3 immunoassay
MX2012002371A (es) * 2009-08-25 2012-06-08 Bg Medicine Inc Galectina-3 y terapia de resincronizacion cardiaca.

Similar Documents

Publication Publication Date Title
JP2007508527A5 (cg-RX-API-DMAC7.html)
US10132809B2 (en) Differential expression of protein markers for the diagnosis and treatment of eosinophilic esophagitis
WO2004046729A3 (en) Bodily fluid markers of tissue hypoxia
JP6941324B2 (ja) 新規な肝硬変または肝線維症のマーカー
EP2287618A3 (en) Method for diagnosing neuro-degenerative disease
JP2011177182A5 (cg-RX-API-DMAC7.html)
EP1849002A4 (en) Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin
DK1342794T3 (da) Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker
PE20121029A1 (es) Marcadores de riesgo para enfermedad cardiovascular
JP2012509477A5 (cg-RX-API-DMAC7.html)
ATE531820T1 (de) Gesundheitszustandstest
JP2009524829A5 (cg-RX-API-DMAC7.html)
ATE447715T1 (de) Automatische glykofingerabdruck-strategie
JP2009515556A5 (cg-RX-API-DMAC7.html)
JP2009511905A5 (cg-RX-API-DMAC7.html)
WO2007132120A3 (fr) Procede et methodes de detection de la maladie d'alzheimer
JP2010509576A5 (cg-RX-API-DMAC7.html)
EP2653869A3 (fr) Procédé de diagnostic d'une vascularite
JP2010538252A5 (cg-RX-API-DMAC7.html)
JP2006508326A5 (cg-RX-API-DMAC7.html)
JP2012507268A5 (cg-RX-API-DMAC7.html)
FR2930036B1 (fr) Procede de diagnostic d'une hypertension arterielle pulmonaire.
JP2008547006A5 (cg-RX-API-DMAC7.html)
WO2005118403A3 (en) Methods for detecting gene expression in peripheral blood cells and uses thereof
JP2007536913A5 (cg-RX-API-DMAC7.html)