JP2007506742A5 - - Google Patents

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Publication number
JP2007506742A5
JP2007506742A5 JP2006528071A JP2006528071A JP2007506742A5 JP 2007506742 A5 JP2007506742 A5 JP 2007506742A5 JP 2006528071 A JP2006528071 A JP 2006528071A JP 2006528071 A JP2006528071 A JP 2006528071A JP 2007506742 A5 JP2007506742 A5 JP 2007506742A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
methoxy
phenyl
condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006528071A
Other languages
English (en)
Japanese (ja)
Other versions
JP4719681B2 (ja
JP2007506742A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/030483 external-priority patent/WO2005030217A1/en
Publication of JP2007506742A publication Critical patent/JP2007506742A/ja
Publication of JP2007506742A5 publication Critical patent/JP2007506742A5/ja
Application granted granted Critical
Publication of JP4719681B2 publication Critical patent/JP4719681B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006528071A 2003-09-23 2004-09-17 キナゾリンカリウムチャネル阻害剤 Expired - Fee Related JP4719681B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50513903P 2003-09-23 2003-09-23
US60/505,139 2003-09-23
PCT/US2004/030483 WO2005030217A1 (en) 2003-09-23 2004-09-17 Quinazoline potassium channel inhibitors

Publications (3)

Publication Number Publication Date
JP2007506742A JP2007506742A (ja) 2007-03-22
JP2007506742A5 true JP2007506742A5 (cg-RX-API-DMAC10.html) 2007-08-02
JP4719681B2 JP4719681B2 (ja) 2011-07-06

Family

ID=34392984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006528071A Expired - Fee Related JP4719681B2 (ja) 2003-09-23 2004-09-17 キナゾリンカリウムチャネル阻害剤

Country Status (8)

Country Link
US (1) US7906521B2 (cg-RX-API-DMAC10.html)
EP (1) EP1667685B1 (cg-RX-API-DMAC10.html)
JP (1) JP4719681B2 (cg-RX-API-DMAC10.html)
CN (1) CN1856310A (cg-RX-API-DMAC10.html)
AT (1) ATE549024T1 (cg-RX-API-DMAC10.html)
AU (1) AU2004275718B2 (cg-RX-API-DMAC10.html)
CA (1) CA2539476C (cg-RX-API-DMAC10.html)
WO (1) WO2005030217A1 (cg-RX-API-DMAC10.html)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0416730D0 (en) 2004-07-27 2004-09-01 Novartis Ag Organic compounds
EP1781635B1 (en) 2004-07-29 2012-06-13 Merck Sharp & Dohme Corp. Potassium channel inhibitors
US7569589B2 (en) 2004-07-29 2009-08-04 Merck & Co., Inc. Potassium channel inhibitors
WO2006098969A2 (en) * 2005-03-09 2006-09-21 Merck & Co., Inc. Quinazolinone t-type calcium channel antagonists
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds
US8158146B2 (en) 2005-09-28 2012-04-17 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
WO2007098386A1 (en) * 2006-02-17 2007-08-30 Janssen Pharmaceutica N.V. Pyrazolylquinazolinones as potassium channel openers
DE102006019589A1 (de) * 2006-04-27 2007-10-31 Sanofi-Aventis Deutschland Gmbh Inhibitoren des TASK-1 und Task-3 Ionenkanals
WO2008112320A1 (en) * 2007-03-15 2008-09-18 The Trustees Of The University Of Pennsylvania Inhibition of ion channel function
AU2008275674A1 (en) * 2007-07-10 2009-01-15 Merck & Co., Inc. Quinazolinone T-type calcium channel antagonists
CN101654441B (zh) * 2008-08-19 2012-10-03 信谊药厂 抗凝化合物、组合物及其用途
WO2010088195A1 (en) * 2009-01-30 2010-08-05 Boehringer Ingelheim International Gmbh Azaquinazolinediones useful as chymase inhibitors
EP2473487B1 (en) 2009-09-03 2016-10-26 Bristol-Myers Squibb Company Quinazolines as potassium ion channel inhibitors
CN103130730B (zh) * 2011-11-24 2015-04-08 南开大学 喹唑啉类衍生物及其制备方法、抗hiv活性和抗tmv活性
JP6484555B2 (ja) * 2013-08-29 2019-03-13 京都薬品工業株式会社 新規芳香族化合物およびその用途
US11465978B2 (en) 2013-09-11 2022-10-11 The Administrators Of The Tulane Educational Fund Anthranilic amides and the use thereof
JOP20190086A1 (ar) 2016-10-21 2019-04-18 Novartis Ag مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1311573A (en) * 1970-04-27 1973-03-28 Hisamitsu Pharmaceutical Co Quinazolinedione derivatives
US4016166A (en) * 1973-12-14 1977-04-05 Hisamitsu Pharmaceutical Co., Inc. 1-Nitrophenylquinazoline-2,4(1H,3H)-diones
JPS6020387B2 (ja) * 1975-12-26 1985-05-21 久光製薬株式会社 新規なキナゾリン誘導体の製造法
LU74369A1 (cg-RX-API-DMAC10.html) * 1976-02-18 1977-09-12
US5155110A (en) * 1987-10-27 1992-10-13 Warner-Lambert Company Fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition
ES2132254T3 (es) * 1992-09-14 1999-08-16 Forssmann Wolf Georg Prof Dr Nueva utilizacion de inhibidores de la fosfodiesterasa iv.
US5891904A (en) * 1992-09-14 1999-04-06 Wolf-Georg Forssmann Use of inhibitors of phosphodiesterase IV
HUT76640A (en) * 1995-08-17 1997-10-28 Chinoin Gyogyszer Es Vegyeszet Compounds of pharmaceutical activity cyclic amide derivatives, pharmaceutical compositions containing them, process for producing them and their use
US6054487A (en) * 1997-03-18 2000-04-25 Basf Aktiengesellschaft Methods and compositions for modulating responsiveness to corticosteroids
US6037345A (en) * 1998-01-13 2000-03-14 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to quinazolinedione and pyridopyrimidinedione derivatives
CA2421819C (en) 2000-09-20 2010-03-09 Merck & Co., Inc. Isoquinolinone potassium channel inhibitors
WO2005117876A1 (en) * 2004-06-01 2005-12-15 University Of Virginia Patent Foundation Dual small molecule inhibitors of cancer and angiogenesis

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