AR035807A1 - Composicion farmaceutica de liberacion modificada apropiada para compuestos antiarritmicos, procedimiento para su preparacion, y uso de esta composicion para la manufactura de un medicamento para ser usado en la profilaxis o tratamiento de una arritmia - Google Patents
Composicion farmaceutica de liberacion modificada apropiada para compuestos antiarritmicos, procedimiento para su preparacion, y uso de esta composicion para la manufactura de un medicamento para ser usado en la profilaxis o tratamiento de una arritmiaInfo
- Publication number
- AR035807A1 AR035807A1 ARP020101188A ARP020101188A AR035807A1 AR 035807 A1 AR035807 A1 AR 035807A1 AR P020101188 A ARP020101188 A AR P020101188A AR P020101188 A ARP020101188 A AR P020101188A AR 035807 A1 AR035807 A1 AR 035807A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- prophylaxis
- compounds
- procedure
- manufacture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Composición farmacéutica de liberación modificada que comprende 4-({3-[7-(3,3-dimetil-2-oxobutil)-9-oxa-3,7-diazabiciclo-[3.3.1]non-3-il]propil}amino)benzonitrilo, 2-{7-[3-(4-ciano-anilino)propil]-9-oxa-3,7-diazabiciclo [3.3.1]non-3-il}etilcarbamato de ter-butilo, 2-{7-[4-(4-cianofenil)butil]-9-oxa-3,7-diazabiciclo[3.3.1]non-3-il}etilcarbamato de ter-butilo o 2-{7-[(2S)-3-(4-cianofenoxi)-2-hidroxipropil]-9-oxa-3,7-diazabiciclo[3.3-1[}etilcarbamato de ter-butilo o una sal farmacéuticamente aceptable de cualquiera de estos compuestos, en particular una composición de liberación modificada de matriz polimérica gelificante. También se dan a conocer el procedimiento para su preparación y el uso de esta composición para la manufactura de un medicamento. Las composiciones son útiles para la profilaxis y/o tratamiento de arritmias cardíacas como por ejemplo, arritmia atrial, arritmia ventricular, fibrilación atrial y palpitación atrial.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101326A SE0101326D0 (sv) | 2001-04-12 | 2001-04-12 | Pharmaceutical formulation |
| SE0101325A SE0101325D0 (sv) | 2001-04-12 | 2001-04-12 | Pharmaceutical formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR035807A1 true AR035807A1 (es) | 2004-07-14 |
Family
ID=26655442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020101188A AR035807A1 (es) | 2001-04-12 | 2002-04-02 | Composicion farmaceutica de liberacion modificada apropiada para compuestos antiarritmicos, procedimiento para su preparacion, y uso de esta composicion para la manufactura de un medicamento para ser usado en la profilaxis o tratamiento de una arritmia |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20040132798A1 (es) |
| EP (1) | EP1389211A1 (es) |
| JP (1) | JP2004525969A (es) |
| KR (1) | KR20040005917A (es) |
| CN (1) | CN1279916C (es) |
| AR (1) | AR035807A1 (es) |
| BG (1) | BG108235A (es) |
| BR (1) | BR0208830A (es) |
| CA (1) | CA2443464A1 (es) |
| CZ (1) | CZ20032759A3 (es) |
| EE (1) | EE200300506A (es) |
| HU (1) | HUP0303481A3 (es) |
| IL (1) | IL158035A0 (es) |
| IS (1) | IS6990A (es) |
| MX (1) | MXPA03009213A (es) |
| MY (1) | MY141595A (es) |
| NO (1) | NO20034528L (es) |
| NZ (1) | NZ528559A (es) |
| PL (1) | PL367182A1 (es) |
| RU (1) | RU2003129229A (es) |
| SK (1) | SK12542003A3 (es) |
| TW (1) | TWI259836B (es) |
| WO (1) | WO2002083687A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2409552A1 (en) | 2001-10-25 | 2003-04-25 | Depomed, Inc. | Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract |
| US20030091630A1 (en) * | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
| US20060134210A1 (en) * | 2004-12-22 | 2006-06-22 | Astrazeneca Ab | Solid dosage form comprising proton pump inhibitor and suspension made thereof |
| CA2595894C (en) | 2005-01-31 | 2013-09-10 | Kanji Takada | Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment |
| AU2006258293B2 (en) | 2005-06-13 | 2010-06-17 | Astrazeneca Ab | New oxabispidine compounds for the treatment of cardiac arrhythmias |
| TW200940110A (en) * | 2008-02-22 | 2009-10-01 | Astrazeneca Ab | Pharmaceutical formulation comprising oxabispidines |
| US10702485B2 (en) | 2011-07-09 | 2020-07-07 | Syntrix Biosystems Inc. | Compositions and methods for overcoming resistance to tramadol |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3732094A1 (de) * | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
| US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
| DE4402933A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
| SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
| PL350907A1 (en) * | 1999-04-09 | 2003-02-10 | Astrazeneca Ab | Adamantane derivatives |
| SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
| SE0101327D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
| SE0101329D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Pharmaceutical formulation |
-
2002
- 2002-04-01 TW TW091106494A patent/TWI259836B/zh not_active IP Right Cessation
- 2002-04-02 AR ARP020101188A patent/AR035807A1/es not_active Application Discontinuation
- 2002-04-10 MY MYPI20021315A patent/MY141595A/en unknown
- 2002-04-12 IL IL15803502A patent/IL158035A0/xx unknown
- 2002-04-12 BR BR0208830-4A patent/BR0208830A/pt not_active IP Right Cessation
- 2002-04-12 EE EEP200300506A patent/EE200300506A/xx unknown
- 2002-04-12 CA CA002443464A patent/CA2443464A1/en not_active Abandoned
- 2002-04-12 RU RU2003129229/04A patent/RU2003129229A/ru not_active Application Discontinuation
- 2002-04-12 HU HU0303481A patent/HUP0303481A3/hu unknown
- 2002-04-12 WO PCT/SE2002/000724 patent/WO2002083687A1/en not_active Application Discontinuation
- 2002-04-12 CN CNB028116348A patent/CN1279916C/zh not_active Expired - Fee Related
- 2002-04-12 JP JP2002581442A patent/JP2004525969A/ja not_active Withdrawn
- 2002-04-12 KR KR10-2003-7013419A patent/KR20040005917A/ko not_active Application Discontinuation
- 2002-04-12 SK SK1254-2003A patent/SK12542003A3/sk unknown
- 2002-04-12 MX MXPA03009213A patent/MXPA03009213A/es unknown
- 2002-04-12 PL PL02367182A patent/PL367182A1/xx unknown
- 2002-04-12 US US10/474,591 patent/US20040132798A1/en not_active Abandoned
- 2002-04-12 CZ CZ20032759A patent/CZ20032759A3/cs unknown
- 2002-04-12 EP EP02723010A patent/EP1389211A1/en not_active Withdrawn
- 2002-04-12 NZ NZ528559A patent/NZ528559A/en unknown
-
2003
- 2003-10-06 BG BG108235A patent/BG108235A/bg unknown
- 2003-10-09 NO NO20034528A patent/NO20034528L/no not_active Application Discontinuation
- 2003-10-10 IS IS6990A patent/IS6990A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0303481A2 (hu) | 2004-01-28 |
| TWI259836B (en) | 2006-08-11 |
| BR0208830A (pt) | 2004-03-09 |
| CA2443464A1 (en) | 2002-10-24 |
| NO20034528L (no) | 2003-12-08 |
| CZ20032759A3 (cs) | 2004-01-14 |
| HUP0303481A3 (en) | 2005-04-28 |
| CN1514838A (zh) | 2004-07-21 |
| CN1279916C (zh) | 2006-10-18 |
| KR20040005917A (ko) | 2004-01-16 |
| NZ528559A (en) | 2005-03-24 |
| MY141595A (en) | 2010-05-14 |
| PL367182A1 (en) | 2005-02-21 |
| MXPA03009213A (es) | 2004-01-29 |
| IL158035A0 (en) | 2004-03-28 |
| RU2003129229A (ru) | 2005-04-10 |
| SK12542003A3 (sk) | 2004-03-02 |
| US20040132798A1 (en) | 2004-07-08 |
| EP1389211A1 (en) | 2004-02-18 |
| EE200300506A (et) | 2004-02-16 |
| WO2002083687A1 (en) | 2002-10-24 |
| NO20034528D0 (no) | 2003-10-09 |
| IS6990A (is) | 2003-10-10 |
| BG108235A (bg) | 2005-04-30 |
| JP2004525969A (ja) | 2004-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |