JP2007506084A - ナノ粒子コンジュゲート及びその製造方法 - Google Patents

ナノ粒子コンジュゲート及びその製造方法 Download PDF

Info

Publication number
JP2007506084A
JP2007506084A JP2006526693A JP2006526693A JP2007506084A JP 2007506084 A JP2007506084 A JP 2007506084A JP 2006526693 A JP2006526693 A JP 2006526693A JP 2006526693 A JP2006526693 A JP 2006526693A JP 2007506084 A JP2007506084 A JP 2007506084A
Authority
JP
Japan
Prior art keywords
nanoparticles
peptide
nanoparticle
nanoparticle conjugate
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006526693A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007506084A5 (enExample
Inventor
デイビッド ガース ファーニグ
ジェン チー キム サン
ジョン アーサー スミス
リチャード クリストファー ドティ
ラファエル レヴィー
Original Assignee
ザ・ユニバーシティ・オブ・リバプール
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ・ユニバーシティ・オブ・リバプール filed Critical ザ・ユニバーシティ・オブ・リバプール
Publication of JP2007506084A publication Critical patent/JP2007506084A/ja
Publication of JP2007506084A5 publication Critical patent/JP2007506084A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/588Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with semiconductor nanocrystal label, e.g. quantum dots

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Peptides Or Proteins (AREA)
JP2006526693A 2003-09-19 2004-09-20 ナノ粒子コンジュゲート及びその製造方法 Pending JP2007506084A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0321937.5A GB0321937D0 (en) 2003-09-19 2003-09-19 Nanoparticle conjugates and method of production thereof
PCT/GB2004/003986 WO2005029076A2 (en) 2003-09-19 2004-09-20 Nanoparticle conjugates and method of production thereof

Publications (2)

Publication Number Publication Date
JP2007506084A true JP2007506084A (ja) 2007-03-15
JP2007506084A5 JP2007506084A5 (enExample) 2007-10-25

Family

ID=29266267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006526693A Pending JP2007506084A (ja) 2003-09-19 2004-09-20 ナノ粒子コンジュゲート及びその製造方法

Country Status (7)

Country Link
US (1) US20070054337A1 (enExample)
EP (1) EP1664776A2 (enExample)
JP (1) JP2007506084A (enExample)
AU (1) AU2004274694A1 (enExample)
CA (1) CA2539501A1 (enExample)
GB (1) GB0321937D0 (enExample)
WO (1) WO2005029076A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009529004A (ja) * 2006-02-27 2009-08-13 インダストリー−アカデミック コーポレーション ファウンデーション,ヨンセイ ユニバーシティ 相転移リガンドでコートされた水溶性磁性または水溶性金属酸化物ナノ粒子とその製造方法及び用途
JP2015521198A (ja) * 2012-05-29 2015-07-27 ザ ユニバーシティ オブ バーミンガム 付着したdna修復阻害剤及び核局在化シグナル要素を含むナノパーティクル

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9434770B2 (en) * 2004-10-07 2016-09-06 Tapas K Das Gupta Modified cupredoxin derived peptides
JP5059312B2 (ja) * 2005-09-16 2012-10-24 Hoya株式会社 高分散性リン酸カルシウム系化合物ナノ粒子及びその製造方法
KR20090059148A (ko) 2006-09-11 2009-06-10 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 쿠프레독신 유래된 펩티드의 변형 및 이의 이용 방법
JP5746469B2 (ja) 2006-10-04 2015-07-08 ブルックヘブン サイエンス アソシエイツ Dnaによって導かれたナノ粒子凝集
WO2008134586A1 (en) * 2007-04-27 2008-11-06 The Regents Of The University Of California Site-specific conjugation of ligands to nanoparticles
WO2009002837A1 (en) * 2007-06-26 2008-12-31 Massachusetts Institute Of Technology Controlled modification of semiconductor nanocrystals
CN101113457B (zh) * 2007-07-04 2010-05-19 中国科学院长春应用化学研究所 富精氨酸寡肽-金纳米粒子细胞传输载体合成方法
EP2240782A2 (en) * 2008-02-04 2010-10-20 Ulive Enterprises Limited Nanoparticle conjugates
US8729012B2 (en) * 2008-06-02 2014-05-20 Brookhaven Science Associates, Llc Controllable assembly and disassembly of nanoparticle systems via protein and DNA agents
KR101014246B1 (ko) * 2008-07-03 2011-02-16 포항공과대학교 산학협력단 페하 민감성 금속 나노 입자 및 이의 제조 방법.
US20100261185A1 (en) 2009-03-27 2010-10-14 Life Technologies Corporation Labeled enzyme compositions, methods and systems
WO2011011631A2 (en) * 2009-07-22 2011-01-27 Samuel Zalipsky Nucleic acid delivery vehicles
WO2011031478A1 (en) * 2009-08-27 2011-03-17 Brown University Fe3o4-m(au-like)-nanoparticles for antibody-conserving target-specific platin delivery
US8378075B2 (en) * 2009-10-27 2013-02-19 The United States Of America, As Represented By The Secretary Of The Navy Covalent attachment of peptides and biological molecules to luminescent semiconductor nanocrystals
US9114107B2 (en) 2010-10-05 2015-08-25 Drexel University Compositions for inhibiting virus entry and promoting virolysis, and methods thereof
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
DK3489685T3 (da) 2011-11-21 2023-12-04 Zoetis Services Llc Signalforstærkning i sidestrømning og tilsvarende immunoassays
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
CN102896325B (zh) * 2012-10-12 2014-04-16 江南大学 一种基于无机小分子盐的金纳米棒手性自组装材料制备方法
CN103058133B (zh) * 2013-01-30 2014-01-08 江南大学 一种基于非手性小分子组装手性纳米材料的制备方法
US9234078B2 (en) 2013-03-21 2016-01-12 The Regents Of The University Of Michigan Conjugated gold nanoparticles
US9233138B2 (en) 2013-10-22 2016-01-12 Drexel University Compositions for promoting HIV-1 virolysis and methods using same
SG10201912301XA (en) 2013-11-04 2020-02-27 Uti Lp Methods and compositions for sustained immunotherapy
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
US12011480B2 (en) 2015-05-06 2024-06-18 Uti Limited Partnership Nanoparticle compositions for sustained therapy
JP6944438B2 (ja) 2015-08-04 2021-10-06 ゾエティス サービシズ リミテッド ライアビリティ カンパニー 溶液ベースのプラズモン特異的結合パートナーアッセイにおけるシグナル増幅
WO2018094213A1 (en) * 2016-11-18 2018-05-24 Kansas State University Research Foundation Microfluidics-based nanobiosensors and devices
KR102654470B1 (ko) 2017-01-30 2024-04-05 조에티스 서비시즈 엘엘씨 용액-기반 플라스몬 특이적-결합 파트너 검정 및 금속성 나노구조체
CN111741746A (zh) 2017-11-29 2020-10-02 乌第有限合伙公司 治疗自身免疫性疾病的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086881A (en) * 1998-05-15 2000-07-11 Children's Medical Center Corp. Spatially aligned conjugated composition having a thioether bond linkage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6121425A (en) * 1994-07-29 2000-09-19 Nanoprobes, Inc. Metal-lipid molecules
US6368877B1 (en) * 1997-06-25 2002-04-09 Massachusetts Institute Of Technology Self-assembling peptide surfaces for cell patterning and interactions
US6953656B2 (en) * 2000-07-14 2005-10-11 Massachusetts Institute Of Technology Direct, externally imposed control of polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086881A (en) * 1998-05-15 2000-07-11 Children's Medical Center Corp. Spatially aligned conjugated composition having a thioether bond linkage

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009529004A (ja) * 2006-02-27 2009-08-13 インダストリー−アカデミック コーポレーション ファウンデーション,ヨンセイ ユニバーシティ 相転移リガンドでコートされた水溶性磁性または水溶性金属酸化物ナノ粒子とその製造方法及び用途
JP2015521198A (ja) * 2012-05-29 2015-07-27 ザ ユニバーシティ オブ バーミンガム 付着したdna修復阻害剤及び核局在化シグナル要素を含むナノパーティクル

Also Published As

Publication number Publication date
AU2004274694A1 (en) 2005-03-31
US20070054337A1 (en) 2007-03-08
CA2539501A1 (en) 2005-03-31
GB0321937D0 (en) 2003-10-22
WO2005029076A2 (en) 2005-03-31
EP1664776A2 (en) 2006-06-07
WO2005029076A3 (en) 2005-09-15

Similar Documents

Publication Publication Date Title
JP2007506084A (ja) ナノ粒子コンジュゲート及びその製造方法
CN102066941B (zh) 用于生物传感器的新型Au/Ag核-壳复合材料
US20110165647A1 (en) Nanoparticle conjugates
US7253277B2 (en) Nanoparticle polyanion conjugates and methods of use thereof in detecting analytes
CN102559170B (zh) 一种鲁米诺发光功能化的纳米银及其制备方法和应用
US20120202218A1 (en) Detection method and device based on nanoparticle aggregation
CN104316698A (zh) 固定有抗原的免疫荧光载片的制备方法和由该方法制备的免疫荧光载片
JP2011505580A (ja) バイオプローブと、その製造方法、それを利用した分析装置及び分析方法
Wang et al. Epitope imprinted polymer nanoparticles containing fluorescent quantum dots for specific recognition of human serum albumin
Yang et al. A novel platform for high sensitivity determination of PbP2a based on gold nanoparticles composited graphitized mesoporous carbon and doxorubicin loaded hollow gold nanospheres
JP2006508095A (ja) 粒子の生物活性化
KR20040083095A (ko) 페라이트 결합 유기 물질 및 이의 제조 방법
Qiao et al. Antibody and DNA dual-labeled gold nanoparticles: Stability and reactivity
Woolley et al. From particle to platelet: optimization of a stable, high brightness fluorescent nanoparticle based cell detection platform
Cháfer-Pericás et al. Functionalized inorganic nanoparticles used as labels in solid-phase immunoassays
JP4335526B2 (ja) コロイド構造体および非コロイド構造体による結合スピーシーズの検出
US20180003709A1 (en) Heterodimeric core-shell nanoparticle in which raman-active molecules are located at a binding portion of a nanoparticle heterodimer, use thereof, and method for preparing same
Powell et al. Giant platinum clusters: 2-nm covalent metal cluster labels
Hainfeld et al. Nanoparticle molecular labels
JP2010002393A (ja) 標的物質の検出方法
Brayner Current Approaches in Natural BiopolymerNanoparticle Hybrid Functional Materials: From Drug Delivery to Bio-Detection Applications
Elbayomy Modification and Application of Gold Nanorods in Surface Enhanced Raman Scattering Based Assays
Liu Developing Novel Interface and Signal Amplification Strategies for Study of Biological Interactions by Surface Plasmon Resonance (SPR) and SPRimaing
HK1158309B (en) Novel au / ag core-shell composite useful for biosensor

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070905

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070905

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091118

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100414