JP2007504268A5 - - Google Patents
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- JP2007504268A5 JP2007504268A5 JP2006526176A JP2006526176A JP2007504268A5 JP 2007504268 A5 JP2007504268 A5 JP 2007504268A5 JP 2006526176 A JP2006526176 A JP 2006526176A JP 2006526176 A JP2006526176 A JP 2006526176A JP 2007504268 A5 JP2007504268 A5 JP 2007504268A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition
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- igg
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000203 mixture Substances 0.000 claims 13
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 238000009472 formulation Methods 0.000 claims 7
- 229940027941 immunoglobulin g Drugs 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 2
- 239000000499 gel Substances 0.000 claims 2
- 239000002674 ointment Substances 0.000 claims 2
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 239000003125 aqueous solvent Substances 0.000 claims 1
- 210000005178 buccal mucosa Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000008309 hydrophilic cream Substances 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 239000007937 lozenge Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 238000011200 topical administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Claims (13)
- a)HSV-中和抗体水準に基づくスクリーニングがなされていない供血者から得られるプールされたヒト血漿から調製された免疫グロブリンG(IgG)の有効量；
b)局所調剤における使用に適した少なくとも1種の製薬学的に許容可能な賦形剤
を含んでなる、哺乳動物のヘルペス疾患の処置または予防における局所投与のための製薬学的組成物。 - 皮膚または他の影響を受けた領域からの吸収を促進する少なくとも1種の物質をさらに含んでなる請求項1の製薬学的組成物。
- IgGの有効量が組成物の約0.05重量%〜約35重量%である請求項1の製薬学的組成物。
- IgGの有効量が組成物の約3重量%〜約16重量%である請求項1の製薬学的組成物。
- 組成物がパラフィン系軟膏、水-混和性軟膏、水中油型クリームおよびゲル剤よりなる群から選ばれる調剤として調製される請求項1の製薬学的組成物。
- 組成物が眼用に適した調剤として調製される請求項1の製薬学的組成物。
- IgGの有効量が水性溶媒中に溶解または懸濁される請求項6の製薬学的組
成物。 - 調剤がIgGの持続的輸送または睡眠中の使用に適合したものである請求項6の製薬学的組成物。
- 組成物が頬粘膜への適用に適した調剤として調製される請求項1の製薬学的組成物。
- 調剤がロゼンジ剤である請求項9の製薬学的組成物。
- 組成物が膣用に適した調剤として調製される請求項1の製薬学的組成物。
- 調剤が膣挿入に適した投与形態である請求項11の製薬学的組成物。
- 投与形態が坐剤、ゲル剤または錠剤である請求項12の製薬学的組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/656,781 US6984492B2 (en) | 2003-09-05 | 2003-09-05 | Methods and compositions for treating herpes infections |
| PCT/US2004/028559 WO2005025617A2 (en) | 2003-09-05 | 2004-09-02 | Methods and compositions for treating herpes infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007504268A JP2007504268A (ja) | 2007-03-01 |
| JP2007504268A5 true JP2007504268A5 (ja) | 2007-10-18 |
Family
ID=34226428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006526176A Withdrawn JP2007504268A (ja) | 2003-09-05 | 2004-09-02 | ヘルペス感染症を処置するための方法および組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6984492B2 (ja) |
| EP (1) | EP1663309A2 (ja) |
| JP (1) | JP2007504268A (ja) |
| KR (1) | KR20060107509A (ja) |
| CN (1) | CN1845756A (ja) |
| AU (1) | AU2004272001A1 (ja) |
| BR (1) | BRPI0414139A (ja) |
| CA (1) | CA2537360A1 (ja) |
| IL (1) | IL173805A0 (ja) |
| NO (1) | NO20061184L (ja) |
| NZ (1) | NZ546303A (ja) |
| WO (2) | WO2005023303A1 (ja) |
| ZA (1) | ZA200602738B (ja) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2248825T3 (pl) * | 2009-05-04 | 2013-04-30 | Ribovax Biotechnologies Sa | Fragmenty przeciwciała wiążące antygen do zastosowania w leczeniu i diagnozowaniu chorób oczu |
| US20130172536A1 (en) * | 2011-08-16 | 2013-07-04 | Shenzhen Weiguang Biological Products Co.,Ltd. | Intravenous Cytomegalovirus Human Immune Globulin and Manufacturing Method Thereof |
| US10829543B2 (en) | 2012-10-29 | 2020-11-10 | The University Of North Carolina At Chapel Hill | Compositions and methods for inhibiting pathogen infection |
| WO2014070786A1 (en) * | 2012-10-29 | 2014-05-08 | The University Of North Carolina At Chapel Hill | Compositions and methods for inhibiting pathogen infection |
| CN110938604B (zh) * | 2014-03-03 | 2024-04-05 | 阿尔伯特爱因斯坦医学院 | 重组单纯疱疹病毒2(hsv-2)疫苗载体 |
| US10918712B2 (en) | 2014-03-03 | 2021-02-16 | Albert Einstein College Of Medicine | Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors |
| NZ726168A (en) * | 2014-06-26 | 2022-05-27 | Heidelberg Immunotherapeutics Gmbh | Topical application for an anti-hsv antibody |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| CN105532575A (zh) * | 2016-01-14 | 2016-05-04 | 中国科学院昆明动物研究所 | 一种单纯疱疹病毒感染树鼩动物模型的构建、评估方法及其应用 |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617379A (en) * | 1983-06-14 | 1986-10-14 | Miles Laboratories, Inc. | High titer cytomegalovirus immune serum globulin |
| US4665159A (en) * | 1985-11-07 | 1987-05-12 | Miles Laboratories, Inc. | High titer varicella-zoster immune globulin for intravenous administration |
| US4717564A (en) * | 1985-11-07 | 1988-01-05 | Miles Laboratories, Inc. | High titer varicella-zoster immune globulin for intravenous administration |
| US5258177A (en) * | 1991-12-10 | 1993-11-02 | Alpha Therapeutic Corporation | IgA preparation and process of making the same |
| RU2051054C1 (ru) | 1992-04-14 | 1995-12-27 | Московский научно-исследовательский институт эпидемиологии и микробиологии им.Г.Н.Габричевского | Способ получения препарата противогерпетического иммуноглобулина человека |
| CA2153661A1 (en) * | 1993-01-12 | 1994-07-21 | Anthony George Gristina | Methods and compositions for the direct concentrated delivery of passive immunity |
| US5681565A (en) * | 1993-01-12 | 1997-10-28 | Medical Sciences Research Institute | Methods and compositions for passive immunotherapy |
| WO1998046240A1 (en) * | 1997-04-15 | 1998-10-22 | Advanced Viral Research Corp. | Topical treatment of skin diseases and eye afflictions |
| US5886154A (en) * | 1997-06-20 | 1999-03-23 | Lebing; Wytold R. | Chromatographic method for high yield purification and viral inactivation of antibodies |
-
2003
- 2003-09-05 US US10/656,781 patent/US6984492B2/en not_active Expired - Fee Related
-
2004
- 2004-08-24 WO PCT/EP2004/009434 patent/WO2005023303A1/en active Application Filing
- 2004-09-01 BR BRPI0414139-3A patent/BRPI0414139A/pt not_active Application Discontinuation
- 2004-09-02 WO PCT/US2004/028559 patent/WO2005025617A2/en active Application Filing
- 2004-09-02 EP EP04782951A patent/EP1663309A2/en not_active Withdrawn
- 2004-09-02 KR KR1020067004565A patent/KR20060107509A/ko not_active Application Discontinuation
- 2004-09-02 CA CA002537360A patent/CA2537360A1/en not_active Abandoned
- 2004-09-02 CN CNA2004800253052A patent/CN1845756A/zh active Pending
- 2004-09-02 NZ NZ546303A patent/NZ546303A/en not_active IP Right Cessation
- 2004-09-02 AU AU2004272001A patent/AU2004272001A1/en not_active Abandoned
- 2004-09-02 JP JP2006526176A patent/JP2007504268A/ja not_active Withdrawn
-
2006
- 2006-02-19 IL IL173805A patent/IL173805A0/en unknown
- 2006-03-03 US US11/367,772 patent/US20060198848A1/en not_active Abandoned
- 2006-03-14 NO NO20061184A patent/NO20061184L/no not_active Application Discontinuation
- 2006-04-03 ZA ZA200602738A patent/ZA200602738B/xx unknown
-
2009
- 2009-03-19 US US12/407,188 patent/US20090232798A1/en not_active Abandoned
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