JP2007210988A5 - - Google Patents

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Publication number
JP2007210988A5
JP2007210988A5 JP2006060189A JP2006060189A JP2007210988A5 JP 2007210988 A5 JP2007210988 A5 JP 2007210988A5 JP 2006060189 A JP2006060189 A JP 2006060189A JP 2006060189 A JP2006060189 A JP 2006060189A JP 2007210988 A5 JP2007210988 A5 JP 2007210988A5
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JP
Japan
Prior art keywords
ethanol
coleus
forskolin
alcohol
commercial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006060189A
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Japanese (ja)
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JP2007210988A (en
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Publication date
Application filed filed Critical
Priority to JP2006060189A priority Critical patent/JP2007210988A/en
Priority claimed from JP2006060189A external-priority patent/JP2007210988A/en
Priority to NZ552997A priority patent/NZ552997A/en
Priority to AU2007200442A priority patent/AU2007200442A1/en
Priority to NZ568652A priority patent/NZ568652A/en
Publication of JP2007210988A publication Critical patent/JP2007210988A/en
Publication of JP2007210988A5 publication Critical patent/JP2007210988A5/ja
Pending legal-status Critical Current

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Claims (10)

フォルスコリン、イソフォルスコリン又は7-デアセチルフォルスコリンを含むことを特徴とする、テストステロン、エストロゲン又はHGHの血清レベルを生理学的に増大させるための組成物。 Forskolin, iso forskolin or 7, characterized in that de-including acetyl forskolin, testosterone, compositions because physiologically increased serum levels of estrogen or HGH. テストステロン、エストロゲン又はHGHの標的組織レベルを生理学的に増大するのに使用される、請求項１記載の組成物。   The composition of claim 1 used to physiologically increase target tissue levels of testosterone, estrogen or HGH. 1-デオキシフォルスコリン、9-デオキシフォルスコリン及び1,9-ジデオキシフォルスコリンを含む、請求項１又は２記載の組成物。   The composition according to claim 1 or 2, comprising 1-deoxyforskolin, 9-deoxyforskolin and 1,9-dideoxyforskolin. 乾燥コレウス根を微粉砕し、水とアルコール、C1-C4アルコール、二塩化メチレン、トルエン、又はヘキサンの混合物から選ばれた溶媒で抽出し、抽出物を濃縮し、ヘプタン、ペンタン、ヘキサンから選ばれた無極性溶媒で沈殿させ、濾過し、水とアルコールの混合物で逆抽出し、アルコール中で結晶化することからなるイソフォルスコリンの商業的製造方法。   Finely pulverize the dried Coleus root and extract with a solvent selected from a mixture of water and alcohol, C1-C4 alcohol, methylene dichloride, toluene, or hexane, concentrate the extract, and select from heptane, pentane, hexane. A method for the commercial production of isoforskolin comprising precipitating with a non-polar solvent, filtering, back-extracting with a mixture of water and alcohol and crystallizing in alcohol. 乾燥コレウス根を微粉砕し、根粉末を45℃〜55℃の温度及び300バールの圧力で超臨界二酸化炭素及び補助溶媒エタノールで抽出し、エタノール中で結晶化することからなるイソフォルスコリンの商業的製造方法。   Isoforskolin commercial consisting of milling dried Coleus roots, extracting the root powder with supercritical carbon dioxide and co-solvent ethanol at a temperature of 45 ° C to 55 ° C and pressure of 300 bar and crystallizing in ethanol Manufacturing method. 乾燥コレウス根を微粉砕し、根粉末を45℃〜55℃の温度及び300バールの圧力で超臨界二酸化炭素及び補助溶媒エタノールで抽出し、リパーゼ酵素で加水分解し、エタノール中で結晶化することからなる7-デアセチルフォルスコリンの商業的製造方法。   Grinding dried Coleus roots, extracting the root powder with supercritical carbon dioxide and co-solvent ethanol at a temperature of 45 ° C to 55 ° C and a pressure of 300 bar, hydrolyzing with lipase enzyme and crystallizing in ethanol A process for the commercial production of 7-deacetylforskolin, comprising: 精油を除去するための乾燥コレウス根の商業的超臨界又は亜臨界抽出方法。   Commercial supercritical or subcritical extraction method of dried Coleus roots to remove essential oils. 臨界温度以下で110バールから400バールまでの範囲の圧力下で超臨界ガス中に存在する種々の量のエタノールを含む超臨界二酸化炭素による商業的方法。   Commercial process with supercritical carbon dioxide containing various amounts of ethanol present in supercritical gas under pressures ranging from 110 bar to 400 bar below the critical temperature. 組成物が約10mg〜約100mgの毎日の用量で投与される形態である、請求項１から３のいずれか１項記載の組成物。   4. The composition of any one of claims 1 to 3, wherein the composition is in a form that is administered at a daily dose of about 10 mg to about 100 mg. 約１％〜約100％のフォルスコリンを含む、請求項１から３のいずれか１項記載の組成物。   4. A composition according to any one of claims 1 to 3, comprising from about 1% to about 100% forskolin.
JP2006060189A 2006-02-07 2006-02-07 Composition for physiologically increasing male and female hormone by diterpene forskolin and its derivative Pending JP2007210988A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2006060189A JP2007210988A (en) 2006-02-07 2006-02-07 Composition for physiologically increasing male and female hormone by diterpene forskolin and its derivative
NZ552997A NZ552997A (en) 2006-02-07 2007-02-02 Composition for physiological increase of male and female hormones with diterpene forskolin and its derivatives
AU2007200442A AU2007200442A1 (en) 2006-02-07 2007-02-02 Composition for physiological increase of male and female hormones with diterpene forskolin and its derivatives
NZ568652A NZ568652A (en) 2006-02-07 2007-02-02 Commercial process for making forskolin and its derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006060189A JP2007210988A (en) 2006-02-07 2006-02-07 Composition for physiologically increasing male and female hormone by diterpene forskolin and its derivative

Publications (2)

Publication Number Publication Date
JP2007210988A JP2007210988A (en) 2007-08-23
JP2007210988A5 true JP2007210988A5 (en) 2009-03-26

Family

ID=38456616

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006060189A Pending JP2007210988A (en) 2006-02-07 2006-02-07 Composition for physiologically increasing male and female hormone by diterpene forskolin and its derivative

Country Status (3)

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JP (1) JP2007210988A (en)
AU (1) AU2007200442A1 (en)
NZ (2) NZ552997A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101656834B1 (en) * 2009-07-17 2016-09-13 한국생명공학연구원 A composition for preventing and treating bone disease comprising colforsin daropate
CN101843366B (en) * 2010-04-29 2012-01-04 云南省玉溪市溶剂厂有限公司 Tobacco plasticizer containing isoforskolin and preparation method thereof
CN105693684B (en) * 2016-01-22 2018-10-09 昆明医科大学 A kind of preparation method of isoforskolin
CN107929785A (en) * 2017-12-16 2018-04-20 蒋央芳 A kind of essential oil and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06133731A (en) * 1992-10-23 1994-05-17 Zenetsukusu Kk Diet food
JPH1042829A (en) * 1996-07-30 1998-02-17 Zenetsukusu Kk Health food
JPH11313637A (en) * 1998-05-07 1999-11-16 Sanpo Kk New food using coleus forskohlii root
JP4432069B2 (en) * 2002-09-03 2010-03-17 ビーエイチエヌ株式会社 Obesity inhibitor
US6960300B2 (en) * 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications

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