JP2007185189A5 - - Google Patents
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- Publication number
- JP2007185189A5 JP2007185189A5 JP2006355330A JP2006355330A JP2007185189A5 JP 2007185189 A5 JP2007185189 A5 JP 2007185189A5 JP 2006355330 A JP2006355330 A JP 2006355330A JP 2006355330 A JP2006355330 A JP 2006355330A JP 2007185189 A5 JP2007185189 A5 JP 2007185189A5
- Authority
- JP
- Japan
- Prior art keywords
- dopaminergic neuron
- progenitor cells
- cell population
- neuron progenitor
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims 43
- 210000005064 dopaminergic neuron Anatomy 0.000 claims 40
- 210000000130 stem cell Anatomy 0.000 claims 33
- 238000000034 method Methods 0.000 claims 31
- 230000011278 mitosis Effects 0.000 claims 17
- 239000002773 nucleotide Substances 0.000 claims 14
- 125000003729 nucleotide group Chemical group 0.000 claims 14
- 239000002157 polynucleotide Substances 0.000 claims 14
- 102000040430 polynucleotide Human genes 0.000 claims 14
- 108091033319 polynucleotide Proteins 0.000 claims 14
- 230000000295 complement effect Effects 0.000 claims 10
- 210000001259 mesencephalon Anatomy 0.000 claims 9
- 230000036456 mitotic arrest Effects 0.000 claims 8
- 239000000523 sample Substances 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 230000004069 differentiation Effects 0.000 claims 6
- 230000004770 neurodegeneration Effects 0.000 claims 4
- 208000015122 neurodegenerative disease Diseases 0.000 claims 4
- 208000018737 Parkinson disease Diseases 0.000 claims 3
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 230000009744 cell cycle exit Effects 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 230000002062 proliferating effect Effects 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000035800 maturation Effects 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000002771 cell marker Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000004748 cultured cell Anatomy 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006355330A JP4717797B2 (ja) | 2004-07-22 | 2006-12-28 | Lrp4/Corinドーパミン産生ニューロン前駆細胞マーカー |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004213743 | 2004-07-22 | ||
| JP2004213743 | 2004-07-22 | ||
| JP2004315060 | 2004-10-29 | ||
| JP2004315060 | 2004-10-29 | ||
| JP2006355330A JP4717797B2 (ja) | 2004-07-22 | 2006-12-28 | Lrp4/Corinドーパミン産生ニューロン前駆細胞マーカー |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006524554A Division JP3996627B2 (ja) | 2004-07-22 | 2005-07-22 | Lrp4/Corinドーパミン産生ニューロン前駆細胞マーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007185189A JP2007185189A (ja) | 2007-07-26 |
| JP2007185189A5 true JP2007185189A5 (enExample) | 2008-09-04 |
| JP4717797B2 JP4717797B2 (ja) | 2011-07-06 |
Family
ID=38340788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006355330A Expired - Lifetime JP4717797B2 (ja) | 2004-07-22 | 2006-12-28 | Lrp4/Corinドーパミン産生ニューロン前駆細胞マーカー |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4717797B2 (enExample) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074906A2 (en) * | 2001-03-16 | 2002-09-26 | Eli Lilly And Company | Lp mammalian proteins; related reagents |
| JPWO2002103007A1 (ja) * | 2001-06-19 | 2004-09-30 | エーザイ株式会社 | Dna断片の量の均一化方法及びサブトラクション法 |
| AU2003276430A1 (en) * | 2002-06-14 | 2003-12-31 | Stowers Institute For Medical Research | Wise/sost nucleic acid sequences and amino acid sequences |
| EP1561814B1 (en) * | 2002-10-22 | 2010-12-22 | Eisai R&D Management Co., Ltd. | Gene specifically expressed in postmitotic dopaminergic neuron precursor cells |
-
2006
- 2006-12-28 JP JP2006355330A patent/JP4717797B2/ja not_active Expired - Lifetime
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