JP2007155441A - 微小流体装置 - Google Patents
微小流体装置 Download PDFInfo
- Publication number
- JP2007155441A JP2007155441A JP2005349571A JP2005349571A JP2007155441A JP 2007155441 A JP2007155441 A JP 2007155441A JP 2005349571 A JP2005349571 A JP 2005349571A JP 2005349571 A JP2005349571 A JP 2005349571A JP 2007155441 A JP2007155441 A JP 2007155441A
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- microchannel
- microfluidic device
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0825—Test strips
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2076—Utilizing diverse fluids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2224—Structure of body of device
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/2931—Diverse fluid containing pressure systems
- Y10T137/3003—Fluid separating traps or vents
- Y10T137/3021—Discriminating outlet for liquid
Abstract
【解決手段】微小流体が流れる略一定の高さの微小流路16が内部に形成され、その微小流路内に柱状体12cなどが形成されることによって微小流体の一部に幅が狭い部分が形成された微小流体装置10において、微小流路を上方に拡張する拡張凹部14cを、幅が狭い部分の上流側に形成し、必要に応じて、拡張凹部に対向する微小流路の底面の部分に、微小流路の長手方向に略平行に延びる複数の隆起部を形成する。
【選択図】図5
Description
12 下側プレート部材
12a 微細溝
12b 拡幅部
12c 柱状体
12d 隆起部
14 上側プレート部材
14a 貫通孔(注入口)
14b 貫通孔(排出口)
14c 拡張凹部
16 微小流路
18 気泡
Claims (10)
- 微小流体が流れる微小流路が内部に形成された微小流体装置において、前記微小流路内の気泡を捕捉して前記微小流路内の所定の領域に気泡が到達するのを防止する気泡捕捉部として、前記微小流路を上方に拡張する拡張凹部を、前記所定の領域の上流側に形成したことを特徴とする、微小流体装置。
- 前記拡張凹部が、前記微小流路を略鉛直方向上方に拡張していることを特徴とする、請求項1に記載の微小流体装置。
- 前記拡張凹部が、前記微小流路の長手方向に略垂直な横方向に延びていることを特徴とする、請求項1または2に記載の微小流体装置。
- 前記微小流路の高さが、前記拡張凹部以外の部分において略一定の高さであることを特徴とする、請求項1乃至3のいずれかに記載の微小流体装置。
- 前記微小流路内の前記所定の領域に、前記気泡の通過を妨げる程度に幅が狭い部分が形成されていることを特徴とする、請求項1乃至4のいずれかに記載の微小流体装置。
- 前記幅が狭い部分が、前記微小流路の内部に設けられた柱状体によって形成されていることを特徴とする、請求項5に記載の微小流体装置。
- 前記微小流路の高さが、前記拡張凹部の下流側の前記拡張凹部に隣接する部分において前記幅が狭い部分の幅以下であることを特徴とする、請求項5または6に記載の微小流体装置。
- 前記拡張凹部に対向する前記微小流路の底面の部分に、前記微小流路の長手方向に略平行に延びる複数の隆起部が形成されていることを特徴とする、請求項1乃至7のいずれかに記載の微小流体装置。
- 前記複数の隆起部の上面が、前記微小流路の上流側から下流側に向かって前記微小流路の底面を徐々に隆起させるように傾斜して形成されていることを特徴とする、請求項8に記載の微小流体装置。
- 前記複数の隆起部の間隔が、前記幅が狭い部分の幅以下であることを特徴とする、請求項9に記載の微小流体装置。
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005349571A JP4685611B2 (ja) | 2005-12-02 | 2005-12-02 | 微小流体装置 |
DK06024533T DK1792655T3 (da) | 2005-12-02 | 2006-11-27 | Mikrofluidisk indretning indeholdende en boblefælde |
DE200660003613 DE602006003613D1 (de) | 2005-12-02 | 2006-11-27 | Mikrofluidische Vorrichtung enthaltend eine Blasenfalle |
EP20060024533 EP1792655B1 (en) | 2005-12-02 | 2006-11-27 | Microfluidic device comprising a bubble trap |
AT06024533T ATE413921T1 (de) | 2005-12-02 | 2006-11-27 | Mikrofluidische vorrichtung enthaltend eine blasenfalle |
US11/605,593 US7686029B2 (en) | 2005-12-02 | 2006-11-28 | Microfluidic device for trapping air bubbles |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005349571A JP4685611B2 (ja) | 2005-12-02 | 2005-12-02 | 微小流体装置 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2007155441A true JP2007155441A (ja) | 2007-06-21 |
JP2007155441A5 JP2007155441A5 (ja) | 2008-11-27 |
JP4685611B2 JP4685611B2 (ja) | 2011-05-18 |
Family
ID=37820649
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005349571A Expired - Fee Related JP4685611B2 (ja) | 2005-12-02 | 2005-12-02 | 微小流体装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US7686029B2 (ja) |
EP (1) | EP1792655B1 (ja) |
JP (1) | JP4685611B2 (ja) |
AT (1) | ATE413921T1 (ja) |
DE (1) | DE602006003613D1 (ja) |
DK (1) | DK1792655T3 (ja) |
Cited By (11)
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WO2007125642A1 (ja) * | 2006-04-05 | 2007-11-08 | Nikkiso Co., Ltd. | 混合器、混合装置及び医療成分測定ユニット |
JP2009097912A (ja) * | 2007-10-15 | 2009-05-07 | Rohm Co Ltd | 血液検査用マイクロチップ |
WO2009060695A1 (ja) * | 2007-11-09 | 2009-05-14 | Konica Minolta Medical & Graphic, Inc. | マイクロチップ検査装置 |
JP2009109232A (ja) * | 2007-10-26 | 2009-05-21 | Josho Gakuen | 固液分離機能を有する装置及びその製造方法 |
WO2011078115A1 (ja) * | 2009-12-25 | 2011-06-30 | 学校法人常翔学園 | 固液分離機能を有する装置、μ-TASデバイス及び固液分離方法 |
US8367424B2 (en) | 2007-10-15 | 2013-02-05 | Rohm Co., Ltd. | Microchip and method of using the same |
JP2014126517A (ja) * | 2012-12-27 | 2014-07-07 | Rohm Co Ltd | マイクロチップ |
CN105699613A (zh) * | 2015-07-02 | 2016-06-22 | 清华大学深圳研究生院 | 水质监测系统 |
JP2017075910A (ja) * | 2015-10-16 | 2017-04-20 | ウシオ電機株式会社 | 吸光度測定装置および吸光度測定方法 |
JP2018049026A (ja) * | 2014-10-14 | 2018-03-29 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | オープンセル発泡体を用いた血液サンプルの管理 |
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---|---|---|---|---|
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US20080038713A1 (en) * | 2005-11-02 | 2008-02-14 | Affymetrix, Inc. | System and Method for Biological Assay |
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US9211378B2 (en) | 2010-10-22 | 2015-12-15 | Cequr Sa | Methods and systems for dosing a medicament |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5170570A (en) * | 1974-12-16 | 1976-06-18 | Keiji Inochi | Ekitaikara kihoo bunrisuru kihobunriki |
JPS5248174A (en) * | 1975-10-15 | 1977-04-16 | Sanyo Electric Co Ltd | Gas-liquid separator |
JPH09257748A (ja) * | 1996-03-21 | 1997-10-03 | Technol Res Assoc Of Medical & Welfare Apparatus | 液体回路 |
JP2001518614A (ja) * | 1997-09-26 | 2001-10-16 | ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 移動ミクロ弁 |
JP2003294613A (ja) * | 2002-03-29 | 2003-10-15 | Japan Science & Technology Corp | 表面プラズモン共鳴センサ |
JP2004093558A (ja) * | 2002-07-12 | 2004-03-25 | Mitsubishi Chemicals Corp | 分析用チップ、分析用チップユニット及び分析装置ならびに分析用チップの作製方法 |
US20040228764A1 (en) * | 2003-05-13 | 2004-11-18 | Ambri Ltd. | Sampling system |
WO2005022169A1 (ja) * | 2003-09-01 | 2005-03-10 | Nec Corporation | チップ |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6368871B1 (en) * | 1997-08-13 | 2002-04-09 | Cepheid | Non-planar microstructures for manipulation of fluid samples |
JP2002001102A (ja) | 2000-06-20 | 2002-01-08 | Kanagawa Acad Of Sci & Technol | マイクロチャンネル構造 |
JP4736199B2 (ja) | 2001-02-13 | 2011-07-27 | 大日本印刷株式会社 | フィルター |
EP1258720B1 (en) * | 2001-05-15 | 2007-07-18 | Sysmex Corporation | Measuring unit and rotary valve for use therein |
JP3775305B2 (ja) | 2002-01-31 | 2006-05-17 | コニカミノルタホールディングス株式会社 | 液体混合機構及び液体混合方法 |
US7118676B2 (en) * | 2003-09-04 | 2006-10-10 | Arryx, Inc. | Multiple laminar flow-based particle and cellular separation with laser steering |
CN102620959B (zh) * | 2002-12-26 | 2015-12-16 | 梅索磅秤技术有限公司 | 检定盒及其使用方法 |
JP4252913B2 (ja) | 2004-02-25 | 2009-04-08 | 株式会社日立製作所 | エンジンの制御装置 |
DE202004011272U1 (de) | 2004-07-17 | 2004-09-09 | Tecan Trading Ag | Vorrichtung zum Bereitstellen einer Hybridisierkammer und zum Beeinflussen von Luftblasen in derselben |
WO2006132666A1 (en) * | 2005-06-06 | 2006-12-14 | Decision Biomarkers, Inc. | Assays based on liquid flow over arrays |
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2005
- 2005-12-02 JP JP2005349571A patent/JP4685611B2/ja not_active Expired - Fee Related
-
2006
- 2006-11-27 DE DE200660003613 patent/DE602006003613D1/de active Active
- 2006-11-27 EP EP20060024533 patent/EP1792655B1/en not_active Not-in-force
- 2006-11-27 AT AT06024533T patent/ATE413921T1/de not_active IP Right Cessation
- 2006-11-27 DK DK06024533T patent/DK1792655T3/da active
- 2006-11-28 US US11/605,593 patent/US7686029B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5170570A (en) * | 1974-12-16 | 1976-06-18 | Keiji Inochi | Ekitaikara kihoo bunrisuru kihobunriki |
JPS5248174A (en) * | 1975-10-15 | 1977-04-16 | Sanyo Electric Co Ltd | Gas-liquid separator |
JPH09257748A (ja) * | 1996-03-21 | 1997-10-03 | Technol Res Assoc Of Medical & Welfare Apparatus | 液体回路 |
JP2001518614A (ja) * | 1997-09-26 | 2001-10-16 | ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、ミシガン | 移動ミクロ弁 |
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Also Published As
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EP1792655B1 (en) | 2008-11-12 |
JP4685611B2 (ja) | 2011-05-18 |
ATE413921T1 (de) | 2008-11-15 |
US20070125434A1 (en) | 2007-06-07 |
DE602006003613D1 (de) | 2008-12-24 |
EP1792655A1 (en) | 2007-06-06 |
DK1792655T3 (da) | 2009-03-09 |
US7686029B2 (en) | 2010-03-30 |
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