JP2007054072A5 - - Google Patents
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- Publication number
- JP2007054072A5 JP2007054072A5 JP2006258117A JP2006258117A JP2007054072A5 JP 2007054072 A5 JP2007054072 A5 JP 2007054072A5 JP 2006258117 A JP2006258117 A JP 2006258117A JP 2006258117 A JP2006258117 A JP 2006258117A JP 2007054072 A5 JP2007054072 A5 JP 2007054072A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- amino acid
- nucleotide sequence
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 90
- 229920001184 polypeptide Polymers 0.000 claims 89
- 102000004196 processed proteins & peptides Human genes 0.000 claims 89
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 33
- 125000003275 alpha amino acid group Chemical group 0.000 claims 33
- 239000002773 nucleotide Substances 0.000 claims 31
- 125000003729 nucleotide group Chemical group 0.000 claims 31
- 239000012634 fragment Substances 0.000 claims 24
- 238000000034 method Methods 0.000 claims 21
- 230000000694 effects Effects 0.000 claims 20
- 239000011230 binding agent Substances 0.000 claims 18
- 102000039446 nucleic acids Human genes 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 18
- 101150043652 secs-1 gene Proteins 0.000 claims 16
- 210000004027 cell Anatomy 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 230000000295 complement effect Effects 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- 210000004899 c-terminal region Anatomy 0.000 claims 4
- 238000012217 deletion Methods 0.000 claims 4
- 230000037430 deletion Effects 0.000 claims 4
- 238000003780 insertion Methods 0.000 claims 4
- 230000037431 insertion Effects 0.000 claims 4
- 230000001575 pathological effect Effects 0.000 claims 4
- 238000006467 substitution reaction Methods 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 239000012528 membrane Substances 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 2
- 238000012986 modification Methods 0.000 claims 2
- 230000004048 modification Effects 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 239000013603 viral vector Substances 0.000 claims 2
- 229920003169 water-soluble polymer Polymers 0.000 claims 2
- 206010006895 Cachexia Diseases 0.000 claims 1
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 1
- 229920002307 Dextran Polymers 0.000 claims 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- 206010018366 Glomerulonephritis acute Diseases 0.000 claims 1
- 208000037147 Hypercalcaemia Diseases 0.000 claims 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 206010031243 Osteogenesis imperfecta Diseases 0.000 claims 1
- 208000001132 Osteoporosis Diseases 0.000 claims 1
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 1
- 231100000851 acute glomerulonephritis Toxicity 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000001668 ameliorated effect Effects 0.000 claims 1
- 230000003302 anti-idiotype Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 208000018706 hematopoietic system disease Diseases 0.000 claims 1
- 229920001519 homopolymer Polymers 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 230000000148 hypercalcaemia Effects 0.000 claims 1
- 208000030915 hypercalcemia disease Diseases 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 claims 1
- 201000008383 nephritis Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 208000002865 osteopetrosis Diseases 0.000 claims 1
- 208000028169 periodontal disease Diseases 0.000 claims 1
- 229920000191 poly(N-vinyl pyrrolidone) Polymers 0.000 claims 1
- 229920001583 poly(oxyethylated polyols) Polymers 0.000 claims 1
- 229920001451 polypropylene glycol Polymers 0.000 claims 1
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59908700A | 2000-06-21 | 2000-06-21 | |
| US09/724,000 US7329729B1 (en) | 2000-06-21 | 2000-11-28 | Secreted epithelial colon stromal-1 molecules and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002504645A Division JP2004503220A (ja) | 2000-06-21 | 2000-11-28 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008309136A Division JP2009148256A (ja) | 2000-06-21 | 2008-12-03 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007054072A JP2007054072A (ja) | 2007-03-08 |
| JP2007054072A5 true JP2007054072A5 (enExample) | 2008-01-17 |
Family
ID=24398156
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002504645A Withdrawn JP2004503220A (ja) | 2000-06-21 | 2000-11-28 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
| JP2006258117A Pending JP2007054072A (ja) | 2000-06-21 | 2006-09-22 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
| JP2008309136A Pending JP2009148256A (ja) | 2000-06-21 | 2008-12-03 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002504645A Withdrawn JP2004503220A (ja) | 2000-06-21 | 2000-11-28 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008309136A Pending JP2009148256A (ja) | 2000-06-21 | 2008-12-03 | 分泌型結腸上皮間質性−１ポリペプチド、これをコードする核酸、およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7329729B1 (enExample) |
| EP (1) | EP1294871A1 (enExample) |
| JP (3) | JP2004503220A (enExample) |
| AU (2) | AU2001219323A1 (enExample) |
| CA (1) | CA2414228A1 (enExample) |
| MX (1) | MXPA02012717A (enExample) |
| WO (1) | WO2001098497A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2500438A3 (en) * | 2002-09-25 | 2012-11-28 | Genentech, Inc. | Novel compositions and methods for the treatment of psoriasis |
| ATE332703T1 (de) | 2003-02-21 | 2006-08-15 | Univ Arizona | Verwendung von hsp20 zur förderung der wundheilung und / oder zur reduzierung von narbenbildung |
| WO2015069459A1 (en) * | 2013-11-05 | 2015-05-14 | Novartis Ag | Organic compounds |
| CN119074895A (zh) * | 2023-11-06 | 2024-12-06 | 中南大学湘雅二医院 | 一类多肽在制备治疗肥胖及其合并症的药物、食品或保健品中的用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001021658A1 (en) * | 1999-09-24 | 2001-03-29 | Human Genome Sciences, Inc. | 32 human secreted proteins |
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030004311A1 (en) * | 1997-06-18 | 2003-01-02 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US20030022239A1 (en) * | 1997-06-18 | 2003-01-30 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| IL128131A0 (en) | 1999-01-19 | 1999-11-30 | Compugen Ltd | Novel nucleic acid and amino acid sequences |
| WO2000043509A2 (en) * | 1999-01-19 | 2000-07-27 | Smithkline Beecham Biologicals S.A. | Polynucleotides and their applications in diagnostics |
| CA2405550A1 (en) * | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US20030069180A1 (en) * | 2000-06-09 | 2003-04-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| US20020160382A1 (en) * | 2000-10-11 | 2002-10-31 | Lasek Amy W. | Genes expressed in colon cancer |
| US20030101002A1 (en) * | 2000-11-01 | 2003-05-29 | Bartha Gabor T. | Methods for analyzing gene expression patterns |
-
2000
- 2000-11-28 EP EP00982269A patent/EP1294871A1/en not_active Withdrawn
- 2000-11-28 CA CA002414228A patent/CA2414228A1/en not_active Abandoned
- 2000-11-28 MX MXPA02012717A patent/MXPA02012717A/es not_active Application Discontinuation
- 2000-11-28 JP JP2002504645A patent/JP2004503220A/ja not_active Withdrawn
- 2000-11-28 AU AU2001219323A patent/AU2001219323A1/en not_active Abandoned
- 2000-11-28 US US09/724,000 patent/US7329729B1/en not_active Expired - Fee Related
- 2000-11-28 WO PCT/US2000/032479 patent/WO2001098497A1/en not_active Ceased
-
2006
- 2006-02-28 US US11/364,871 patent/US7629144B2/en not_active Expired - Fee Related
- 2006-03-03 AU AU2006200916A patent/AU2006200916B2/en not_active Ceased
- 2006-09-22 JP JP2006258117A patent/JP2007054072A/ja active Pending
-
2007
- 2007-12-06 US US11/951,797 patent/US20110151579A1/en not_active Abandoned
-
2008
- 2008-12-03 JP JP2008309136A patent/JP2009148256A/ja active Pending
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